| 01 Apr 21 |
r03        | Collingwood Football ClubCollingwood F | 72 - 73 | Brisbane LionsBrisbane Lion |
| 02 Apr 21 |
r03        | North Melbourne Football North Melbour | 39 - 167 | Western BulldogsWestern Bulld |
| 02 Apr 21 |
r03        | Adelaide Football ClubAdelaide Foot | 95 - 85 | Gold Coast Football ClubGold Coast Fo |
| 03 Apr 21 |
r03        | Richmond Football ClubRichmond Foot | 72 - 117 | Sydney SwansSydney Swans |
| 03 Apr 21 |
r03        | Essendon Football ClubEssendon Foot | 143 - 68 | St Kilda Football ClubSt Kilda Foot |
| 03 Apr 21 |
r03        | West Coast EaglesWest Coast Ea | 108 - 71 | Port Adelaide Football ClPort Adelaide |
| 04 Apr 21 |
r03        | Carlton Football ClubCarlton Footb | 109 - 64 | Fremantle Football ClubFremantle Foo |
| 04 Apr 21 |
r03        | Greater Western Sydney GiGreater Weste | 68 - 102 | Melbourne Football ClubMelbourne Foo |
| 05 Apr 21 |
r03        | Geelong Football ClubGeelong Footb | 69 - 64 | Hawthorn Football ClubHawthorn Foot |