| 19 May 26 | r05      | Audax ItalianoAudax Italian | 2 - 0 | Barracas CentralBarracas Cent |
| 19 May 26 | r05 | Montevideo City TorqueMontevideo Ci | 4 - 1 | Deportivo RiestraDeportivo Rie |
| 20 May 26 | r05 | São PauloSão Paulo | 1 - 1 | MillonariosMillonarios |
| 20 May 26 | r05 | América de CaliAmérica de Ca | 1 - 1 | TigreTigre |
| 20 May 26 | r05 | Deportivo CuencaDeportivo Cue | 2 - 2 | RecoletaRecoleta |
| 20 May 26 | r05 | SantosSantos | 2 - 2 | San LorenzoSan Lorenzo |
| 20 May 26 | r05 | Club OlimpiaClub Olimpia | 3 - 1 | Vasco da GamaVasco da Gama |
| 20 May 26 | r05 | Boston RiverBoston River | 3 - 2 | O'HigginsO'Higgins |
| 21 May 26 | r05 | GrêmioGrêmio | 2 - 0 | PalestinoPalestino |
| 21 May 26 | r05 | Independiente PetroleroIndependiente | 0 - 3 | BotafogoBotafogo |
| 21 May 26 | r05 | River PlateRiver Plate | 1 - 1 | BragantinoBragantino |
| 21 May 26 | r05 | Atlético MineiroAtlético Mine | 2 - 0 | CiencianoCienciano |
| 21 May 26 | r05 | Academia Puerto CabelloAcademia Puer | 1 - 1 | Juventud Las PiedrasJuventud Las |
| 22 May 26 | r05 | Racing ClubRacing Club | 2 - 2 | CaracasCaracas |
| 22 May 26 | r05 | BloomingBlooming | 0 - 2 | CaraboboCarabobo |
| 22 May 26 | r05 | MacaráMacará | 0 - 0 | Alianza AtléticoAlianza Atlét |
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