| 13 Aug 21 |
r01    | KMSK DeinzeKMSK Deinze | 1 - 1 | Lierse KempenzonenLierse Kempen |
|
| |
| 22 Aug 21 |
r02 | Lierse KempenzonenLierse Kempen | 2 - 0 | VirtonVirton |
|
| |
| 28 Aug 21 |
r03 | WesterloWesterlo | 3 - 2 | Lierse KempenzonenLierse Kempen |
|
| |
| 12 Sep 21 |
r04 | Lierse KempenzonenLierse Kempen | 4 - 1 | MolenbeekMolenbeek |
|
| |
| 19 Sep 21 |
r05 | Lommel SKLommel SK | 3 - 1 | Lierse KempenzonenLierse Kempen |
|
| |
| 24 Sep 21 |
r06 | Lierse KempenzonenLierse Kempen | 2 - 1 | Waasland-BeverenWaasland-Beve |
|
| |
| 02 Oct 21 |
r07 | Lierse KempenzonenLierse Kempen | 2 - 2 | Mouscron-PeruwelzMouscron-Peru |
|
| |
| 16 Oct 21 |
r08 | VirtonVirton | 2 - 1 | Lierse KempenzonenLierse Kempen |
|
| |
| 23 Oct 21 |
r09 | Lierse KempenzonenLierse Kempen | 2 - 2 | KMSK DeinzeKMSK Deinze |
|
| |
| 30 Oct 21 |
r10 | Waasland-BeverenWaasland-Beve | 1 - 3 | Lierse KempenzonenLierse Kempen |
|
| |
| 07 Nov 21 |
r11 | MolenbeekMolenbeek | 3 - 3 | Lierse KempenzonenLierse Kempen |
|
| |
| 20 Nov 21 |
r12 | Lierse KempenzonenLierse Kempen | 1 - 5 | WesterloWesterlo |
|
| |
| 28 Nov 21 |
r13 | Mouscron-PeruwelzMouscron-Peru | 2 - 1 | Lierse KempenzonenLierse Kempen |
|
| |
| 05 Dec 21 |
r14 | Lierse KempenzonenLierse Kempen | 2 - 2 | Lommel SKLommel SK |
|
| |
| 12 Dec 21 |
r15 | VirtonVirton | 2 - 2 | Lierse KempenzonenLierse Kempen |
|
| |
| 19 Dec 21 |
r16 | Lierse KempenzonenLierse Kempen | 0 - 1 | MolenbeekMolenbeek |
|
| |
| 23 Jan 22 |
r17 | Mouscron-PeruwelzMouscron-Peru | 0 - 0 | Lierse KempenzonenLierse Kempen |
|
| |
| 28 Jan 22 |
r18 | Lommel SKLommel SK | 0 - 1 | Lierse KempenzonenLierse Kempen |
|
| |
| 04 Feb 22 |
r19 | Lierse KempenzonenLierse Kempen | 1 - 1 | KMSK DeinzeKMSK Deinze |
|
| |
| 11 Feb 22 |
r20 | Waasland-BeverenWaasland-Beve | 0 - 1 | Lierse KempenzonenLierse Kempen |
|
| |
| 27 Feb 22 |
r22 | MolenbeekMolenbeek | 3 - 1 | Lierse KempenzonenLierse Kempen |
|
| |
| 05 Mar 22 |
r23 | Lierse KempenzonenLierse Kempen | 0 - 2 | Lommel SKLommel SK |
|
| |
| 13 Mar 22 |
r24 | Lierse KempenzonenLierse Kempen | 0 - 1 | Mouscron-PeruwelzMouscron-Peru |
|
| |
| 16 Mar 22 |
r21 | Lierse KempenzonenLierse Kempen | 1 - 0 | WesterloWesterlo |
|
| |
| 20 Mar 22 |
r25 | WesterloWesterlo | 2 - 0 | Lierse KempenzonenLierse Kempen |
|
| |
| 01 Apr 22 |
r26 | Lierse KempenzonenLierse Kempen | 2 - 0 | Waasland-BeverenWaasland-Beve |
|
| |
| 09 Apr 22 |
r27 | KMSK DeinzeKMSK Deinze | 1 - 2 | Lierse KempenzonenLierse Kempen |
|
| |
| 17 Apr 22 |
r28 | Lierse KempenzonenLierse Kempen | 1 - 1 | VirtonVirton |
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