Season Description
The 2021–22 EPCR Challenge Cup was the eighth edition of the EPCR Challenge Cup, an annual second-tier rugby union competition for professional clubs. Including the predecessor competition, the original European Challenge Cup, this was the 26th edition of European club rugby's second-tier competition.
Due to the COVID-19 pandemic, the tournament format was changed for the previous season. A similar format remained for this season, however, the number of teams was increased from 14 to 15 and an additional six will join from the Champions Cup.
The tournament commenced in December 2021, and concluded with the final on 27 May 2022 at Stade Vélodrome in Marseille, France.
Lyon, who are in their first European final, won the Challenge Cup by defeating Toulon making it their first European title. It is also their first major title since their Champion de France title in 1933.
Event List
|
| | 06 May |
QF  | GloucesterGloucester | 15 - 44 | SaracensSaracens |
| 07 May |
QF  | EdinburghEdinburgh | 30 - 34 | WaspsWasps |
| 07 May |
QF  | Lyon OULyon OU | 35 - 27 | GlasgowGlasgow |
| 08 May |
QF  | RC ToulonnaisRC Toulonnais | 19 - 18 | London IrishLondon Irish |
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