| 21 Sep 20 | r00  | BC Gries OberhoffenBC Gries Ober | 77 - 85 | Gravelines-DunkerqueGravelines-Du |
| 22 Sep 20 | r00 | Paris BasketballParis Basketb | 76 - 85 | Saint-Quentin Basket-BallSaint-Quentin |
| 22 Sep 20 | r00 | ADA BloisADA Blois | 95 - 61 | JSA Bordeaux BasketJSA Bordeaux |
| 22 Sep 20 | r00 | Union Tours Basket MétropUnion Tours B | 83 - 81 | Pau-Lacq-OrthezPau-Lacq-Orth |
| 22 Sep 20 | r00 | ALM Évreux BasketALM Évreux Ba | 79 - 93 | Orléans Loiret BasketOrléans Loire |
| 22 Sep 20 | r00 | BC OrchiesBC Orchies | 0 - 20 | SouffelweyersheimSouffelweyers |
| 22 Sep 20 | r00 | UJAP Quimper 29UJAP Quimper | 20 - 0 | Boulogne-sur-MerBoulogne-sur- |
| 22 Sep 20 | r00 | Élan ChalonÉlan Chalon | 65 - 81 | Fos Provence BasketFos Provence |
| 23 Sep 20 | r00 | Chorale Roanne BasketChorale Roann | 77 - 58 | Antibes SharksAntibes Shark |
| 23 Sep 20 | r00 | Saint-Chamond BasketSaint-Chamond | 73 - 82 | Saint-Vallier Basket DrômSaint-Vallier |
| 23 Sep 20 | r00 | Lille Métropole BCLille Métropo | 75 - 55 | SLUC Nancy BasketSLUC Nancy Ba |
| 13 Oct 20 | r00 | Saint-Vallier Basket DrômSaint-Vallier | 77 - 89 | Boulazac Basket DordogneBoulazac Bask |
| 13 Oct 20 | r00 | Châlons-ReimsChâlons-Reims | 78 - 67 | Saint-Quentin Basket-BallSaint-Quentin |
| 13 Oct 20 | r00 | STB Le HavreSTB Le Havre | 80 - 77 | RouenRouen |
| 13 Oct 20 | r00 | Lille Métropole BCLille Métropo | 69 - 81 | Denain Voltaire BasketDenain Voltai |
| 13 Oct 20 | r00 | Fos Provence BasketFos Provence | 0 - 20 | Chorale Roanne BasketChorale Roann |
| 13 Oct 20 | r00 | Poitiers Basket 86Poitiers Bask | 63 - 86 | ADA BloisADA Blois |
| 13 Oct 20 | r00 | UJAP Quimper 29UJAP Quimper | - | Hermine Nantes BasketHermine Nante |
| 13 Oct 20 | r00 | Étoile Angers BasketÉtoile Angers | 68 - 90 | Orléans Loiret BasketOrléans Loire |
| 14 Oct 20 | r00 | SouffelweyersheimSouffelweyers | 79 - 81 | Gravelines-DunkerqueGravelines-Du |
| 13 Nov 20 | r00 | Le Mans Sarthe BasketLe Mans Sarth | 110 - 54 | Union Tours Basket MétropUnion Tours B |
| 17 Nov 20 | r00 | Chorale Roanne BasketChorale Roann | 93 - 70 | JA Vichy-Clermont MétropoJA Vichy-Cler |
| 20 Nov 20 | r00 | ESSM Le PortelESSM Le Porte | 90 - 92 | ADA BloisADA Blois |
| 21 Nov 20 | r00 | Denain Voltaire BasketDenain Voltai | 100 - 107 | Gravelines-DunkerqueGravelines-Du |
| 08 Dec 20 | r00 | Orléans Loiret BasketOrléans Loire | 90 - 81 | Boulazac Basket DordogneBoulazac Bask |
| 08 Jan 21 | r00 | LimogesLimoges | 99 - 69 | STB Le HavreSTB Le Havre |
| 09 Jan 21 | r00 | CholetCholet | 78 - 82 | StrasbourgStrasbourg |
| 09 Jan 21 | r00 | Chorale Roanne BasketChorale Roann | 74 - 96 | Le Mans Sarthe BasketLe Mans Sarth |
| 09 Jan 21 | r00 | DijonDijon | 79 - 65 | NanterreNanterre |
| 09 Jan 21 | r00 | Orléans Loiret BasketOrléans Loire | 83 - 76 | AS Monaco BasketAS Monaco Bas |
| 10 Jan 21 | r00 | Gravelines-DunkerqueGravelines-Du | 104 - 100 | Châlons-ReimsChâlons-Reims |
| 10 Jan 21 | r00 | Lyon-VilleurbanneLyon-Villeurb | 86 - 77 | Bourg-en-BresseBourg-en-Bres |
| 20 Mar 21 | r00 | DijonDijon | 83 - 63 | StrasbourgStrasbourg |
| 20 Mar 21 | r00 | Le Mans Sarthe BasketLe Mans Sarth | 78 - 84 | Orléans Loiret BasketOrléans Loire |
| 21 Mar 21 | r00 | LimogesLimoges | 72 - 65 | Gravelines-DunkerqueGravelines-Du |
| 06 Apr 21 | r00 | DijonDijon | 107 - 74 | Orléans Loiret BasketOrléans Loire |
| 15 Apr 21 | r00 | Lyon-VilleurbanneLyon-Villeurb | 84 - 82 | LimogesLimoges |
| 24 Apr 21 | r00 | DijonDijon | 61 - 77 | Lyon-VilleurbanneLyon-Villeurb |
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