| 17 Oct 21 | r01  | Uganda Police FCUganda Police | 0 - 2 | VipersVipers |
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| 22 Oct 21 | r02 | BUL Jinja FCBUL Jinja FC | 2 - 1 | Uganda Police FCUganda Police |
| |
| 26 Oct 21 | r03 | Uganda Police FCUganda Police | 0 - 1 | Wakiso GiantsWakiso Giants |
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| 29 Oct 21 | r04 | SC VillaSC Villa | 1 - 0 | Uganda Police FCUganda Police |
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| 02 Nov 21 | r05 | Uganda Police FCUganda Police | 1 - 2 | ExpressExpress |
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| 20 Nov 21 | r06 | OnduparakaOnduparaka | 1 - 0 | Uganda Police FCUganda Police |
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| 26 Nov 21 | r07 | Uganda Police FCUganda Police | 0 - 0 | Mbarara CityMbarara City |
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| 30 Nov 21 | r08 | URAURA | 0 - 0 | Uganda Police FCUganda Police |
| |
| 07 Dec 21 | r09 | Uganda Police FCUganda Police | 2 - 2 | GaddafiGaddafi |
| |
| 10 Dec 21 | r10 | Kampala Capital City AuthKampala Capit | 3 - 1 | Uganda Police FCUganda Police |
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| 18 Dec 21 | r11 | Uganda Police FCUganda Police | 3 - 1 | Busoga UnitedBusoga United |
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| 21 Dec 21 | r12 | Tooro UnitedTooro United | 1 - 3 | Uganda Police FCUganda Police |
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| 29 Dec 21 | r13 | Uganda Police FCUganda Police | 5 - 0 | Bright StarsBright Stars |
| |
| 04 Jan 22 | r14 | UPDFUPDF | 0 - 1 | Uganda Police FCUganda Police |
| |
| 09 Jan 22 | r15 | Uganda Police FCUganda Police | 0 - 0 | Arua HillArua Hill |
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| 05 Feb 22 | r16 | Arua HillArua Hill | 2 - 0 | Uganda Police FCUganda Police |
| |
| 10 Feb 22 | r17 | Uganda Police FCUganda Police | 2 - 2 | UPDFUPDF |
| |
| 15 Feb 22 | r18 | Bright StarsBright Stars | 1 - 1 | Uganda Police FCUganda Police |
| |
| 01 Mar 22 | r19 | Uganda Police FCUganda Police | 4 - 2 | Tooro UnitedTooro United |
| |
| 11 Mar 22 | r20 | Busoga UnitedBusoga United | 0 - 0 | Uganda Police FCUganda Police |
| |
| 15 Mar 22 | r30 | Uganda Police FCUganda Police | 1 - 1 | Kampala Capital City AuthKampala Capit |
| |
| 26 Mar 22 | r21 | GaddafiGaddafi | 0 - 0 | Uganda Police FCUganda Police |
| |
| 29 Mar 22 | r26 | ExpressExpress | 2 - 1 | Uganda Police FCUganda Police |
| |
| 08 Apr 22 | r23 | Uganda Police FCUganda Police | 1 - 4 | OnduparakaOnduparaka |
| |
| 12 Apr 22 | r28 | Mbarara CityMbarara City | 3 - 0 | Uganda Police FCUganda Police |
| |
| 22 Apr 22 | r27 | Uganda Police FCUganda Police | 0 - 2 | URAURA |
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| 02 May 22 | r25 | Uganda Police FCUganda Police | 0 - 0 | SC VillaSC Villa |
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| 07 May 22 | r24 | Wakiso GiantsWakiso Giants | 1 - 3 | Uganda Police FCUganda Police |
| |
| 14 May 22 | r29 | Uganda Police FCUganda Police | 2 - 5 | BUL Jinja FCBUL Jinja FC |
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| 21 May 22 | r22 | VipersVipers | 5 - 0 | Uganda Police FCUganda Police |
Team 2021-2022 Schedules
Buhimba Saints
BUL Jinja
Calvary
Express
Gaddafi
Kampala Capital City Authority
Kitara
Lugazi
Maroons
Mbarara City
NEC FC
SC Villa
Uganda Police
UPDF
URA
Vipers
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