| 14 Aug 21 | r01  | Larkhall AthleticLarkhall Athl | 3 - 1 | SlimbridgeSlimbridge |
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| 16 Aug 21 | r02 | SholingSholing | 0 - 0 | Larkhall AthleticLarkhall Athl |
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| 28 Aug 21 | r03 | Larkhall AthleticLarkhall Athl | 2 - 2 | Bristol Manor FarmBristol Manor |
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| 30 Aug 21 | r04 | Paulton RoversPaulton Rover | 0 - 0 | Larkhall AthleticLarkhall Athl |
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| 11 Sep 21 | r05 | Mangotsfield UnitedMangotsfield | 1 - 4 | Larkhall AthleticLarkhall Athl |
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| 25 Sep 21 | r06 | Larkhall AthleticLarkhall Athl | 3 - 3 | Cinderford TownCinderford To |
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| 02 Oct 21 | r09 | Larkhall AthleticLarkhall Athl | 9 - 1 | Barnstaple TownBarnstaple To |
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| 16 Oct 21 | r10 | Willand RoversWilland Rover | 1 - 0 | Larkhall AthleticLarkhall Athl |
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| 23 Oct 21 | r11 | Larkhall AthleticLarkhall Athl | 1 - 0 | Highworth TownHighworth Tow |
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| 26 Oct 21 | r08 | Lymington TownLymington Tow | 1 - 1 | Larkhall AthleticLarkhall Athl |
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| 06 Nov 21 | r13 | BidefordBideford | 1 - 0 | Larkhall AthleticLarkhall Athl |
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| 17 Nov 21 | r15 | Larkhall AthleticLarkhall Athl | 0 - 3 | SholingSholing |
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| 20 Nov 21 | r16 | SlimbridgeSlimbridge | 2 - 3 | Larkhall AthleticLarkhall Athl |
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| 24 Nov 21 | r14 | Larkhall AthleticLarkhall Athl | 3 - 3 | Evesham UnitedEvesham Unite |
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| 04 Dec 21 | r18 | Larkhall AthleticLarkhall Athl | 1 - 2 | AFC TottonAFC Totton |
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| 11 Dec 21 | r19 | Winchester CityWinchester Ci | 2 - 4 | Larkhall AthleticLarkhall Athl |
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| 27 Dec 21 | r21 | Larkhall AthleticLarkhall Athl | 2 - 1 | Paulton RoversPaulton Rover |
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| 11 Jan 22 | r17 | CirencesterCirencester | 1 - 1 | Larkhall AthleticLarkhall Athl |
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| 29 Jan 22 | r26 | Larkhall AthleticLarkhall Athl | 1 - 1 | Lymington TownLymington Tow |
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| 05 Feb 22 | r27 | Barnstaple TownBarnstaple To | 2 - 1 | Larkhall AthleticLarkhall Athl |
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| 12 Feb 22 | r28 | Larkhall AthleticLarkhall Athl | 1 - 0 | Willand RoversWilland Rover |
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| 26 Feb 22 | r30 | Larkhall AthleticLarkhall Athl | 0 - 1 | Plymouth ParkwayPlymouth Park |
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| 05 Mar 22 | r31 | AFC TottonAFC Totton | 1 - 2 | Larkhall AthleticLarkhall Athl |
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| 09 Mar 22 | r29 | Highworth TownHighworth Tow | 0 - 0 | Larkhall AthleticLarkhall Athl |
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| 12 Mar 22 | r20 | Larkhall AthleticLarkhall Athl | 0 - 0 | Frome TownFrome Town |
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| 15 Mar 22 | r23 | Cinderford TownCinderford To | 1 - 0 | Larkhall AthleticLarkhall Athl |
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| 19 Mar 22 | r32 | Larkhall AthleticLarkhall Athl | 0 - 3 | CirencesterCirencester |
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| 26 Mar 22 | r33 | Frome TownFrome Town | 1 - 1 | Larkhall AthleticLarkhall Athl |
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| 29 Mar 22 | r12 | Plymouth ParkwayPlymouth Park | 1 - 0 | Larkhall AthleticLarkhall Athl |
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| 02 Apr 22 | r34 | Larkhall AthleticLarkhall Athl | 0 - 2 | Winchester CityWinchester Ci |
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| 05 Apr 22 | r22 | Melksham TownMelksham Town | 0 - 0 | Larkhall AthleticLarkhall Athl |
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| 09 Apr 22 | r35 | Larkhall AthleticLarkhall Athl | 0 - 1 | BidefordBideford |
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| 13 Apr 22 | r24 | Larkhall AthleticLarkhall Athl | 0 - 2 | Mangotsfield UnitedMangotsfield |
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| 16 Apr 22 | r36 | Bristol Manor FarmBristol Manor | 3 - 0 | Larkhall AthleticLarkhall Athl |
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| 18 Apr 22 | r37 | Larkhall AthleticLarkhall Athl | 0 - 2 | Melksham TownMelksham Town |
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| 23 Apr 22 | r38 | Evesham UnitedEvesham Unite | 2 - 0 | Larkhall AthleticLarkhall Athl |
Team 2021-2022 Schedules
Bashley
Bideford
Bishop's Cleeve
Bristol Manor Farm
Brixham
Didcot Town
Exmouth Town
Falmouth Town
Frome Town
Hartpury University
Larkhall Athletic
Malvern Town
Melksham Town
Mousehole
Portishead Town
Shaftesbury
Sporting Club Inkberrow
Swindon Supermarine
Tavistock
Westbury United
Willand Rovers
Winchester City
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