| 15 Feb 22 | r01  | Fernández VialFernández Via | 0 - 1 | Rangers de TalcaRangers de Ta |
| 15 Feb 22 | r01 | Deportes Santa CruzDeportes Sant | 1 - 1 | Deportes TemucoDeportes Temu |
| 16 Feb 22 | r01 | MagallanesMagallanes | 2 - 0 | Deportes Puerto MonttDeportes Puer |
| 16 Feb 22 | r01 | CobreloaCobreloa | 2 - 1 | San Luis de QuillotaSan Luis de Q |
| 17 Feb 22 | r01 | Deportes MelipillaDeportes Meli | 0 - 2 | Universidad de ConcepciónUniversidad d |
| |
| 21 Feb 22 | r02 | Deportes TemucoDeportes Temu | 1 - 0 | Santiago WanderersSantiago Wand |
| 22 Feb 22 | r02 | Santiago MorningSantiago Morn | 2 - 1 | Deportes Santa CruzDeportes Sant |
| 22 Feb 22 | r02 | San Luis de QuillotaSan Luis de Q | 0 - 2 | MagallanesMagallanes |
| 23 Feb 22 | r02 | RecoletaRecoleta | 0 - 0 | Fernández VialFernández Via |
| 23 Feb 22 | r02 | Rangers de TalcaRangers de Ta | 1 - 0 | Deportes MelipillaDeportes Meli |
| 25 Feb 22 | r02 | Universidad de ConcepciónUniversidad d | 0 - 2 | CobreloaCobreloa |
| |
| 27 Feb 22 | r03 | Deportes IquiqueDeportes Iqui | 1 - 0 | Deportes TemucoDeportes Temu |
| 01 Mar 22 | r03 | Deportes Santa CruzDeportes Sant | 1 - 2 | MagallanesMagallanes |
| 01 Mar 22 | r03 | Santiago WanderersSantiago Wand | 2 - 2 | Santiago MorningSantiago Morn |
| 02 Mar 22 | r03 | Deportes MelipillaDeportes Meli | 1 - 1 | Deportes Puerto MonttDeportes Puer |
| 02 Mar 22 | r03 | Unión San FelipeUnión San Fel | 1 - 0 | Rangers de TalcaRangers de Ta |
| 03 Mar 22 | r03 | BarnecheaBarnechea | 3 - 1 | San Luis de QuillotaSan Luis de Q |
| 03 Mar 22 | r03 | Universidad de ConcepciónUniversidad d | 0 - 0 | RecoletaRecoleta |
| |
| 07 Mar 22 | r04 | Fernández VialFernández Via | 1 - 0 | Deportes Santa CruzDeportes Sant |
| 08 Mar 22 | r04 | Santiago MorningSantiago Morn | 1 - 1 | Unión San FelipeUnión San Fel |
| 08 Mar 22 | r04 | Deportes Puerto MonttDeportes Puer | 0 - 0 | Deportes IquiqueDeportes Iqui |
| 08 Mar 22 | r04 | Rangers de TalcaRangers de Ta | 1 - 2 | CobreloaCobreloa |
| 09 Mar 22 | r04 | MagallanesMagallanes | 1 - 0 | Universidad de ConcepciónUniversidad d |
| 09 Mar 22 | r04 | San Luis de QuillotaSan Luis de Q | 1 - 1 | Santiago WanderersSantiago Wand |
| 09 Mar 22 | r04 | Deportes CopiapóDeportes Copi | 1 - 1 | BarnecheaBarnechea |
| 11 Mar 22 | r04 | RecoletaRecoleta | 1 - 2 | Deportes MelipillaDeportes Meli |
| |
| 14 Mar 22 | r05 | Deportes TemucoDeportes Temu | 1 - 1 | Fernández VialFernández Via |
| 15 Mar 22 | r05 | Universidad de ConcepciónUniversidad d | 1 - 1 | Deportes Puerto MonttDeportes Puer |
| 15 Mar 22 | r05 | Deportes IquiqueDeportes Iqui | 1 - 1 | MagallanesMagallanes |
| 16 Mar 22 | r05 | Deportes MelipillaDeportes Meli | 2 - 1 | Deportes CopiapóDeportes Copi |
| 16 Mar 22 | r05 | BarnecheaBarnechea | 1 - 1 | RecoletaRecoleta |
| 16 Mar 22 | r05 | San Luis de QuillotaSan Luis de Q | 1 - 2 | Santiago MorningSantiago Morn |
| 16 Mar 22 | r05 | Santiago WanderersSantiago Wand | 1 - 3 | Rangers de TalcaRangers de Ta |
| |
| 22 Mar 22 | r06 | Santiago MorningSantiago Morn | 1 - 0 | Deportes IquiqueDeportes Iqui |
| 22 Mar 22 | r06 | Fernández VialFernández Via | 0 - 0 | Santiago WanderersSantiago Wand |
| 22 Mar 22 | r06 | Deportes CopiapóDeportes Copi | 2 - 1 | Universidad de ConcepciónUniversidad d |
| 22 Mar 22 | r06 | Deportes Puerto MonttDeportes Puer | 3 - 0 | Deportes TemucoDeportes Temu |
| 23 Mar 22 | r06 | MagallanesMagallanes | 2 - 1 | CobreloaCobreloa |
| 23 Mar 22 | r06 | Rangers de TalcaRangers de Ta | 2 - 3 | San Luis de QuillotaSan Luis de Q |
| 23 Mar 22 | r06 | Deportes Santa CruzDeportes Sant | 1 - 1 | BarnecheaBarnechea |
| 23 Mar 22 | r06 | Unión San FelipeUnión San Fel | 1 - 0 | Deportes MelipillaDeportes Meli |
| |
| 02 Apr 22 | r07 | CobreloaCobreloa | 2 - 1 | Deportes Puerto MonttDeportes Puer |
| 03 Apr 22 | r07 | Santiago WanderersSantiago Wand | 0 - 2 | MagallanesMagallanes |
| 03 Apr 22 | r07 | Deportes IquiqueDeportes Iqui | 2 - 2 | Deportes Santa CruzDeportes Sant |
| 04 Apr 22 | r07 | San Luis de QuillotaSan Luis de Q | 0 - 0 | Deportes CopiapóDeportes Copi |
| 04 Apr 22 | r07 | RecoletaRecoleta | 1 - 2 | Rangers de TalcaRangers de Ta |
| 04 Apr 22 | r07 | BarnecheaBarnechea | 0 - 1 | Unión San FelipeUnión San Fel |
| 04 Apr 22 | r07 | Universidad de ConcepciónUniversidad d | 2 - 2 | Fernández VialFernández Via |
| 05 Apr 22 | r07 | Deportes TemucoDeportes Temu | 2 - 1 | Santiago MorningSantiago Morn |
| |
| 08 Apr 22 | r08 | Fernández VialFernández Via | 0 - 0 | Deportes IquiqueDeportes Iqui |
| 08 Apr 22 | r08 | Deportes Puerto MonttDeportes Puer | 1 - 0 | RecoletaRecoleta |
| 09 Apr 22 | r08 | Deportes MelipillaDeportes Meli | 0 - 0 | CobreloaCobreloa |
| 09 Apr 22 | r08 | Deportes CopiapóDeportes Copi | 1 - 1 | Santiago WanderersSantiago Wand |
| 09 Apr 22 | r08 | MagallanesMagallanes | 4 - 0 | BarnecheaBarnechea |
| 11 Apr 22 | r08 | Deportes Santa CruzDeportes Sant | 0 - 0 | Universidad de ConcepciónUniversidad d |
| 12 Apr 22 | r08 | Unión San FelipeUnión San Fel | 2 - 0 | San Luis de QuillotaSan Luis de Q |
| 12 Apr 22 | r08 | Rangers de TalcaRangers de Ta | 3 - 2 | Deportes TemucoDeportes Temu |
| |
| 15 Apr 22 | r09 | Santiago MorningSantiago Morn | 1 - 1 | Fernández VialFernández Via |
| 16 Apr 22 | r09 | RecoletaRecoleta | 3 - 1 | Deportes CopiapóDeportes Copi |
| 16 Apr 22 | r09 | Universidad de ConcepciónUniversidad d | 1 - 3 | Unión San FelipeUnión San Fel |
| 16 Apr 22 | r09 | Deportes TemucoDeportes Temu | 2 - 4 | MagallanesMagallanes |
| 16 Apr 22 | r09 | BarnecheaBarnechea | 1 - 1 | Rangers de TalcaRangers de Ta |
| 16 Apr 22 | r09 | Santiago WanderersSantiago Wand | 2 - 0 | Deportes Puerto MonttDeportes Puer |
| 17 Apr 22 | r09 | Deportes IquiqueDeportes Iqui | 2 - 0 | CobreloaCobreloa |
| 18 Apr 22 | r09 | San Luis de QuillotaSan Luis de Q | 2 - 1 | Deportes MelipillaDeportes Meli |
| |
| 19 Apr 22 | r10 | Deportes CopiapóDeportes Copi | 1 - 0 | Deportes IquiqueDeportes Iqui |
| 20 Apr 22 | r10 | RecoletaRecoleta | 1 - 1 | Santiago MorningSantiago Morn |
| 20 Apr 22 | r10  | Deportes MelipillaDeportes Meli | 2 - 0 | Santiago WanderersSantiago Wand |
| 21 Apr 22 | r10 | CobreloaCobreloa | 3 - 2 | BarnecheaBarnechea |
| 21 Apr 22 | r10 | Rangers de TalcaRangers de Ta | 2 - 1 | Deportes Santa CruzDeportes Sant |
| 21 Apr 22 | r10 | MagallanesMagallanes | 2 - 1 | Fernández VialFernández Via |
| 21 Apr 22 | r10 | Deportes Puerto MonttDeportes Puer | 1 - 1 | San Luis de QuillotaSan Luis de Q |
| 22 Apr 22 | r10 | Unión San FelipeUnión San Fel | 0 - 0 | Deportes TemucoDeportes Temu |
| |
| 24 Apr 22 | r11 | CobreloaCobreloa | 3 - 0 | RecoletaRecoleta |
| 24 Apr 22 | r11 | Deportes IquiqueDeportes Iqui | 0 - 2 | Rangers de TalcaRangers de Ta |
| 25 Apr 22 | r11 | Santiago MorningSantiago Morn | 2 - 3 | MagallanesMagallanes |
| 25 Apr 22 | r11 | BarnecheaBarnechea | 1 - 1 | Universidad de ConcepciónUniversidad d |
| 25 Apr 22 | r11 | Deportes TemucoDeportes Temu | 1 - 1 | Deportes MelipillaDeportes Meli |
| 25 Apr 22 | r11 | Fernández VialFernández Via | 2 - 2 | Deportes Puerto MonttDeportes Puer |
| 26 Apr 22 | r11 | Deportes Santa CruzDeportes Sant | 2 - 2 | Deportes CopiapóDeportes Copi |
| |
| 29 Apr 22 | r12 | Unión San FelipeUnión San Fel | 1 - 1 | CobreloaCobreloa |
| 29 Apr 22 | r12 | Deportes MelipillaDeportes Meli | 2 - 1 | BarnecheaBarnechea |
| 30 Apr 22 | r12 | Universidad de ConcepciónUniversidad d | 2 - 2 | Deportes IquiqueDeportes Iqui |
| 30 Apr 22 | r12 | San Luis de QuillotaSan Luis de Q | 1 - 1 | Deportes TemucoDeportes Temu |
| 30 Apr 22 | r12 | Deportes Puerto MonttDeportes Puer | 3 - 0 | Deportes Santa CruzDeportes Sant |
| 30 Apr 22 | r12 | Deportes CopiapóDeportes Copi | 4 - 0 | Fernández VialFernández Via |
| 30 Apr 22 | r12 | Rangers de TalcaRangers de Ta | 2 - 3 | Santiago MorningSantiago Morn |
| 01 May 22 | r12 | RecoletaRecoleta | 1 - 2 | Santiago WanderersSantiago Wand |
| |
| 06 May 22 | r13 | Santiago WanderersSantiago Wand | 1 - 3 | BarnecheaBarnechea |
| 06 May 22 | r13 | Deportes TemucoDeportes Temu | 1 - 0 | Universidad de ConcepciónUniversidad d |
| 07 May 22 | r13 | Deportes IquiqueDeportes Iqui | 1 - 1 | San Luis de QuillotaSan Luis de Q |
| 07 May 22 | r13 | Rangers de TalcaRangers de Ta | 0 - 1 | Deportes CopiapóDeportes Copi |
| 07 May 22 | r13 | Santiago MorningSantiago Morn | 0 - 0 | Deportes Puerto MonttDeportes Puer |
| 08 May 22 | r13 | Deportes Santa CruzDeportes Sant | 1 - 0 | RecoletaRecoleta |
| 08 May 22 | r13 | MagallanesMagallanes | 1 - 0 | Unión San FelipeUnión San Fel |
| 08 May 22 | r13 | Fernández VialFernández Via | 1 - 1 | Deportes MelipillaDeportes Meli |
| |
| 11 May 22 | r14 | BarnecheaBarnechea | 6 - 2 | Deportes IquiqueDeportes Iqui |
| 11 May 22 | r14 | RecoletaRecoleta | 2 - 1 | Deportes TemucoDeportes Temu |
| 12 May 22 | r14 | Deportes CopiapóDeportes Copi | 2 - 1 | Santiago MorningSantiago Morn |
| 12 May 22 | r14 | Universidad de ConcepciónUniversidad d | 0 - 1 | Rangers de TalcaRangers de Ta |
Team 2022 Schedules
Cobreloa
Curicó Unido
Deportes Antofagasta
Deportes Copiapó
Deportes Iquique
Deportes Puerto Montt
Deportes Recoleta
Deportes Santa Cruz
Deportes Temuco
Magallanes
Rangers de Talca
San Luis de Quillota
San Marcos de Arica
Santiago Wanderers
Unión Española
Unión San Felipe
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