| 28 Feb 21 | r01    | Tokyo VerdyTokyo Verdy | 3 - 0 | Ehime FCEhime FC |
| |
| 07 Mar 21 | r02 | Ehime FCEhime FC | 1 - 1 | JEF United ChibaJEF United Ch |
| |
| 13 Mar 21 | r03 | V-Varen NagasakiV-Varen Nagas | 1 - 1 | Ehime FCEhime FC |
| |
| 21 Mar 21 | r04 | Ehime FCEhime FC | 0 - 1 | Ventforet KofuVentforet Kof |
| |
| 28 Mar 21 | r05 | Tochigi SCTochigi SC | 2 - 1 | Ehime FCEhime FC |
| |
| 04 Apr 21 | r06 | Ehime FCEhime FC | 1 - 2 | Thespakusatsu GunmaThespakusatsu |
| |
| 11 Apr 21 | r07 | Ehime FCEhime FC | 2 - 2 | Fagiano OkayamaFagiano Okaya |
| |
| 17 Apr 21 | r08 | Omiya ArdijaOmiya Ardija | 0 - 1 | Ehime FCEhime FC |
| |
| 21 Apr 21 | r09 | Ehime FCEhime FC | 3 - 1 | Matsumoto YamagaMatsumoto Yam |
| |
| 24 Apr 21 | r10 | Ehime FCEhime FC | 0 - 2 | Albirex NiigataAlbirex Niiga |
| |
| 01 May 21 | r11 | Kyoto SangaKyoto Sanga | 3 - 2 | Ehime FCEhime FC |
| |
| 05 May 21 | r12 | Ehime FCEhime FC | 0 - 0 | Júbilo IwataJúbilo Iwata |
| |
| 08 May 21 | r13 | Ehime FCEhime FC | 1 - 1 | FC RyukyuFC Ryukyu |
| |
| 16 May 21 | r14 | Montedio YamagataMontedio Yama | 1 - 0 | Ehime FCEhime FC |
| |
| 27 May 21 | r15 | SagamiharaSagamihara | 0 - 1 | Ehime FCEhime FC |
| |
| 30 May 21 | r16 | Ehime FCEhime FC | 0 - 5 | Mito HollyHockMito HollyHoc |
| |
| 05 Jun 21 | r17 | Renofa YamaguchiRenofa Yamagu | 2 - 2 | Ehime FCEhime FC |
| |
| 13 Jun 21 | r18 | Ehime FCEhime FC | 1 - 3 | Zweigen KanazawaZweigen Kanaz |
| |
| 20 Jun 21 | r19 | Giravanz KitakyushuGiravanz Kita | 0 - 2 | Ehime FCEhime FC |
| |
| 27 Jun 21 | r20 | Machida ZelviaMachida Zelvi | 5 - 0 | Ehime FCEhime FC |
| |
| 04 Jul 21 | r21 | Ehime FCEhime FC | 1 - 3 | Blaublitz AkitaBlaublitz Aki |
| |
| 11 Jul 21 | r22 | Ventforet KofuVentforet Kof | 1 - 0 | Ehime FCEhime FC |
| |
| 18 Jul 21 | r23 | Ehime FCEhime FC | 2 - 2 | Tokyo VerdyTokyo Verdy |
| |
| 09 Aug 21 | r24 | Thespakusatsu GunmaThespakusatsu | 1 - 1 | Ehime FCEhime FC |
| |
| 15 Aug 21 | r25 | Ehime FCEhime FC | 2 - 2 | Giravanz KitakyushuGiravanz Kita |
| |
| 22 Aug 21 | r26 | Matsumoto YamagaMatsumoto Yam | 0 - 1 | Ehime FCEhime FC |
| |
| 29 Aug 21 | r27 | Ehime FCEhime FC | 0 - 1 | Tochigi SCTochigi SC |
| |
| 05 Sep 21 | r28 | Fagiano OkayamaFagiano Okaya | 0 - 0 | Ehime FCEhime FC |
| |
| 12 Sep 21 | r29 | Ehime FCEhime FC | 3 - 3 | Omiya ArdijaOmiya Ardija |
| |
| 18 Sep 21 | r30  | JEF United ChibaJEF United Ch | 1 - 0 | Ehime FCEhime FC |
| |
| 25 Sep 21 | r31 | Ehime FCEhime FC | 0 - 4 | Montedio YamagataMontedio Yama |
| |
| 02 Oct 21 | r32 | Blaublitz AkitaBlaublitz Aki | 0 - 2 | Ehime FCEhime FC |
| |
| 10 Oct 21 | r33 | Ehime FCEhime FC | 0 - 2 | V-Varen NagasakiV-Varen Nagas |
| |
| 16 Oct 21 | r34 | FC RyukyuFC Ryukyu | 0 - 1 | Ehime FCEhime FC |
| |
| 23 Oct 21 | r35 | Júbilo IwataJúbilo Iwata | 2 - 2 | Ehime FCEhime FC |
| |
| 30 Oct 21 | r36 | Ehime FCEhime FC | 0 - 1 | Kyoto SangaKyoto Sanga |
| |
| 03 Nov 21 | r37 | Zweigen KanazawaZweigen Kanaz | 2 - 1 | Ehime FCEhime FC |
| |
| 07 Nov 21 | r38 | Ehime FCEhime FC | 0 - 0 | Machida ZelviaMachida Zelvi |
| |
| 13 Nov 21 | r39 | Albirex NiigataAlbirex Niiga | 2 - 0 | Ehime FCEhime FC |
| |
| 21 Nov 21 | r40 | Ehime FCEhime FC | 1 - 2 | SagamiharaSagamihara |
| |
| 28 Nov 21 | r41 | Mito HollyHockMito HollyHoc | 2 - 1 | Ehime FCEhime FC |
| |
| 05 Dec 21 | r42 | Ehime FCEhime FC | 1 - 1 | Renofa YamaguchiRenofa Yamagu |
Team 2021 Schedules
Blaublitz Akita
Ehime FC
Fujieda MYFC
Hokkaido Consadole Sapporo
Imabari
Iwaki
JEF United Chiba
Júbilo Iwata
Kataller Toyama
Mito HollyHock
Montedio Yamagata
Oita Trinita
RB Omiya Ardija
Renofa Yamaguchi
Roasso Kumamoto
Sagan Tosu
Tokushima Vortis
V-Varen Nagasaki
Vegalta Sendai
Ventforet Kofu
League Table
List
Poster
= Banner Image 
= Fanart Image 
= Timeline Details