| 10 Oct 20 | r01   | JocoroJocoro | 1 - 0 | FirpoFirpo |
| 10 Oct 20 | r01 | ChalatenangoChalatenango | 3 - 1 | Atlético MarteAtlético Mart |
| 10 Oct 20 | r01 | CD ÁguilaCD Águila | 2 - 1 | LimeñoLimeño |
| 11 Oct 20 | r01 | Isidro MetapánIsidro Metapá | 3 - 1 | FASFAS |
| 11 Oct 20 | r01 | Once DeportivoOnce Deportiv | 4 - 1 | SonsonateSonsonate |
| 11 Oct 20 | r01 | Alianza FCAlianza FC | 3 - 0 | Santa Tecla FCSanta Tecla F |
| |
| 17 Oct 20 | r02 | LimeñoLimeño | 0 - 0 | FirpoFirpo |
| 17 Oct 20 | r02 | FASFAS | 0 - 2 | SonsonateSonsonate |
| 17 Oct 20 | r02 | CD ÁguilaCD Águila | 2 - 0 | JocoroJocoro |
| 18 Oct 20 | r02 | ChalatenangoChalatenango | 0 - 3 | Alianza FCAlianza FC |
| 18 Oct 20 | r02 | Isidro MetapánIsidro Metapá | 6 - 0 | Once DeportivoOnce Deportiv |
| 18 Oct 20 | r02 | Atlético MarteAtlético Mart | 1 - 1 | Santa Tecla FCSanta Tecla F |
| |
| 24 Oct 20 | r03 | SonsonateSonsonate | 1 - 1 | Isidro MetapánIsidro Metapá |
| 25 Oct 20 | r03 | Santa Tecla FCSanta Tecla F | 1 - 1 | ChalatenangoChalatenango |
| 25 Oct 20 | r03 | JocoroJocoro | 5 - 1 | LimeñoLimeño |
| 25 Oct 20 | r03 | Once DeportivoOnce Deportiv | 0 - 0 | FASFAS |
| 25 Oct 20 | r03 | Alianza FCAlianza FC | 1 - 0 | Atlético MarteAtlético Mart |
| |
| 01 Nov 20 | r04 | SonsonateSonsonate | 0 - 1 | Once DeportivoOnce Deportiv |
| 01 Nov 20 | r04 | Santa Tecla FCSanta Tecla F | 1 - 3 | Alianza FCAlianza FC |
| 01 Nov 20 | r04 | LimeñoLimeño | 1 - 0 | CD ÁguilaCD Águila |
| 01 Nov 20 | r04 | FASFAS | 4 - 0 | Isidro MetapánIsidro Metapá |
| 01 Nov 20 | r04 | Atlético MarteAtlético Mart | 3 - 2 | ChalatenangoChalatenango |
| 01 Nov 20 | r04 | FirpoFirpo | 0 - 1 | JocoroJocoro |
| |
| 05 Nov 20 | r03 | FirpoFirpo | 2 - 1 | CD ÁguilaCD Águila |
| |
| 07 Nov 20 | r05 | JocoroJocoro | 2 - 1 | CD ÁguilaCD Águila |
| 07 Nov 20 | r05 | Santa Tecla FCSanta Tecla F | 2 - 1 | Atlético MarteAtlético Mart |
| 08 Nov 20 | r05 | SonsonateSonsonate | 0 - 3 | FASFAS |
| 08 Nov 20 | r05 | Once DeportivoOnce Deportiv | 3 - 1 | Isidro MetapánIsidro Metapá |
| 08 Nov 20 | r05 | FirpoFirpo | 1 - 0 | LimeñoLimeño |
| 08 Nov 20 | r05 | Alianza FCAlianza FC | 1 - 1 | ChalatenangoChalatenango |
| |
| 13 Nov 20 | r06 | CD ÁguilaCD Águila | 1 - 2 | FirpoFirpo |
| 15 Nov 20 | r06 | ChalatenangoChalatenango | 1 - 1 | Santa Tecla FCSanta Tecla F |
| 15 Nov 20 | r06 | Isidro MetapánIsidro Metapá | 2 - 0 | SonsonateSonsonate |
| 15 Nov 20 | r06 | LimeñoLimeño | 4 - 0 | JocoroJocoro |
| 15 Nov 20 | r06 | Atlético MarteAtlético Mart | 1 - 3 | Alianza FCAlianza FC |
| 15 Nov 20 | r06 | FASFAS | 1 - 0 | Once DeportivoOnce Deportiv |
| |
| 21 Nov 20 | r01 | JocoroJocoro | 0 - 0 | CD ÁguilaCD Águila |
| 22 Nov 20 | r01 | SonsonateSonsonate | 1 - 1 | Isidro MetapánIsidro Metapá |
| 22 Nov 20 | r01 | Atlético MarteAtlético Mart | 3 - 5 | Alianza FCAlianza FC |
| 22 Nov 20 | r01 | FASFAS | 0 - 0 | ChalatenangoChalatenango |
| 22 Nov 20 | r01 | FirpoFirpo | 0 - 0 | LimeñoLimeño |
| 22 Nov 20 | r01 | Once DeportivoOnce Deportiv | 2 - 0 | Santa Tecla FCSanta Tecla F |
| |
| 25 Nov 20 | r02 | LimeñoLimeño | 1 - 0 | Once DeportivoOnce Deportiv |
| 25 Nov 20 | r02 | FASFAS | 2 - 0 | FirpoFirpo |
| 26 Nov 20 | r02 | ChalatenangoChalatenango | 0 - 0 | Santa Tecla FCSanta Tecla F |
| 26 Nov 20 | r02 | SonsonateSonsonate | 2 - 2 | Atlético MarteAtlético Mart |
| 26 Nov 20 | r02 | Alianza FCAlianza FC | 4 - 1 | JocoroJocoro |
| 26 Nov 20 | r02 | Isidro MetapánIsidro Metapá | 0 - 1 | CD ÁguilaCD Águila |
| |
| 28 Nov 20 | r03 | CD ÁguilaCD Águila | 1 - 0 | Alianza FCAlianza FC |
| 28 Nov 20 | r03 | Santa Tecla FCSanta Tecla F | 1 - 2 | LimeñoLimeño |
| 29 Nov 20 | r03 | JocoroJocoro | 0 - 0 | SonsonateSonsonate |
| 29 Nov 20 | r03 | Atlético MarteAtlético Mart | 1 - 1 | Isidro MetapánIsidro Metapá |
| 29 Nov 20 | r03 | FirpoFirpo | 0 - 0 | ChalatenangoChalatenango |
| 29 Nov 20 | r03 | Once DeportivoOnce Deportiv | 4 - 2 | FASFAS |
| |
| 06 Dec 20 | r04 | ChalatenangoChalatenango | 3 - 3 | LimeñoLimeño |
| 06 Dec 20 | r04 | SonsonateSonsonate | 0 - 0 | CD ÁguilaCD Águila |
| 06 Dec 20 | r04 | Isidro MetapánIsidro Metapá | 1 - 1 | Alianza FCAlianza FC |
| 06 Dec 20 | r04 | Atlético MarteAtlético Mart | 2 - 1 | JocoroJocoro |
| 06 Dec 20 | r04 | FASFAS | 1 - 1 | Santa Tecla FCSanta Tecla F |
| 06 Dec 20 | r04 | FirpoFirpo | 0 - 1 | Once DeportivoOnce Deportiv |
| |
| 12 Dec 20 | r05 | JocoroJocoro | 3 - 1 | Isidro MetapánIsidro Metapá |
| 12 Dec 20 | r05 | CD ÁguilaCD Águila | 2 - 2 | Atlético MarteAtlético Mart |
| 12 Dec 20 | r05 | Santa Tecla FCSanta Tecla F | 0 - 2 | FirpoFirpo |
| 13 Dec 20 | r05 | Alianza FCAlianza FC | 2 - 1 | SonsonateSonsonate |
| 13 Dec 20 | r05 | Once DeportivoOnce Deportiv | 1 - 0 | ChalatenangoChalatenango |
| 13 Dec 20 | r05 | LimeñoLimeño | 2 - 3 | FASFAS |
| |
| 19 Dec 20 | r06 | CD ÁguilaCD Águila | 2 - 1 | JocoroJocoro |
| 19 Dec 20 | r06 | LimeñoLimeño | 1 - 2 | FirpoFirpo |
| 19 Dec 20 | r06 | Santa Tecla FCSanta Tecla F | 1 - 1 | Once DeportivoOnce Deportiv |
| 20 Dec 20 | r06 | ChalatenangoChalatenango | 1 - 2 | FASFAS |
| 20 Dec 20 | r06 | Alianza FCAlianza FC | 1 - 0 | Atlético MarteAtlético Mart |
| 20 Dec 20 | r06 | Isidro MetapánIsidro Metapá | 2 - 3 | SonsonateSonsonate |
| |
| 23 Dec 20 | r07 | FirpoFirpo | 1 - 2 | FASFAS |
| 23 Dec 20 | r07 | CD ÁguilaCD Águila | 3 - 1 | Isidro MetapánIsidro Metapá |
| 23 Dec 20 | r07 | JocoroJocoro | 1 - 0 | Alianza FCAlianza FC |
| 23 Dec 20 | r07 | Atlético MarteAtlético Mart | 1 - 1 | SonsonateSonsonate |
| 23 Dec 20 | r07 | Once DeportivoOnce Deportiv | 0 - 1 | LimeñoLimeño |
| 24 Dec 20 | r07 | Santa Tecla FCSanta Tecla F | 3 - 1 | ChalatenangoChalatenango |
| |
| 27 Dec 20 | r08 | ChalatenangoChalatenango | 1 - 2 | FirpoFirpo |
| 27 Dec 20 | r08 | SonsonateSonsonate | 1 - 1 | JocoroJocoro |
| 27 Dec 20 | r08 | Alianza FCAlianza FC | 1 - 2 | CD ÁguilaCD Águila |
| 27 Dec 20 | r08 | Isidro MetapánIsidro Metapá | 3 - 2 | Atlético MarteAtlético Mart |
| 27 Dec 20 | r08 | LimeñoLimeño | 3 - 0 | Santa Tecla FCSanta Tecla F |
| 27 Dec 20 | r08 | FASFAS | 0 - 1 | Once DeportivoOnce Deportiv |
| |
| 03 Jan 21 | r09 | Alianza FCAlianza FC | 1 - 0 | Isidro MetapánIsidro Metapá |
| 03 Jan 21 | r09 | CD ÁguilaCD Águila | 1 - 1 | SonsonateSonsonate |
| 03 Jan 21 | r09 | JocoroJocoro | 2 - 2 | Atlético MarteAtlético Mart |
| 03 Jan 21 | r09 | LimeñoLimeño | 2 - 1 | ChalatenangoChalatenango |
| 03 Jan 21 | r09 | Santa Tecla FCSanta Tecla F | 0 - 2 | FASFAS |
| 03 Jan 21 | r09 | Once DeportivoOnce Deportiv | 1 - 1 | FirpoFirpo |
| |
| 09 Jan 21 | r10 | Isidro MetapánIsidro Metapá | 0 - 0 | JocoroJocoro |
| 09 Jan 21 | r10 | Atlético MarteAtlético Mart | 0 - 3 | CD ÁguilaCD Águila |
| 09 Jan 21 | r10 | SonsonateSonsonate | 2 - 3 | Alianza FCAlianza FC |
| 09 Jan 21 | r10 | ChalatenangoChalatenango | 2 - 1 | Once DeportivoOnce Deportiv |
| 09 Jan 21 | r10 | FirpoFirpo | 0 - 3 | Santa Tecla FCSanta Tecla F |
| 09 Jan 21 | r10 | FASFAS | 1 - 0 | LimeñoLimeño |
| |
| 13 Jan 21 | QF | FirpoFirpo | 0 - 2 | CD ÁguilaCD Águila |
| 13 Jan 21 | QF | Once DeportivoOnce Deportiv | 1 - 2 | Alianza FCAlianza FC |
| 14 Jan 21 | QF | JocoroJocoro | 0 - 0 | LimeñoLimeño |
| 15 Jan 21 | QF | SonsonateSonsonate | 0 - 1 | FASFAS |
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