| 29 Jul 21 | r01    | CS HeredianoCS Herediano | 0 - 1 | GuadalupeGuadalupe |
| |
| 01 Aug 21 | r02 | GuadalupeGuadalupe | 1 - 1 | AD San CarlosAD San Carlos |
| |
| 07 Aug 21 | r03 | GuanacastecaGuanacasteca | 0 - 1 | GuadalupeGuadalupe |
| |
| 11 Aug 21 | r04 | GuadalupeGuadalupe | 1 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 15 Aug 21 | r05 | Pérez ZeledónPérez Zeledón | 1 - 1 | GuadalupeGuadalupe |
| |
| 18 Aug 21 | r06 | GuadalupeGuadalupe | 2 - 2 | Sporting San JoseSporting San |
| |
| 25 Aug 21 | r07 | CartaginésCartaginés | 0 - 1 | GuadalupeGuadalupe |
| |
| 28 Aug 21 | r08 | JicaralJicaral | 0 - 0 | GuadalupeGuadalupe |
| |
| 07 Sep 21 | r09 | GuadalupeGuadalupe | 0 - 2 | GreciaGrecia |
| |
| 12 Sep 21 | r10 | GuadalupeGuadalupe | 2 - 4 | AlajuelenseAlajuelense |
| |
| 17 Sep 21 | r11 | Santos de GuápilesSantos de Guá | 2 - 2 | GuadalupeGuadalupe |
| |
| 19 Sep 21 | r12 | GuadalupeGuadalupe | 0 - 2 | CS HeredianoCS Herediano |
| |
| 26 Sep 21 | r13 | AD San CarlosAD San Carlos | 4 - 2 | GuadalupeGuadalupe |
| |
| 01 Oct 21 | r14 | GuadalupeGuadalupe | 1 - 1 | GuanacastecaGuanacasteca |
| |
| 15 Oct 21 | r15 | Deportivo SaprissaDeportivo Sap | 4 - 0 | GuadalupeGuadalupe |
| |
| 18 Oct 21 | r16 | GuadalupeGuadalupe | 0 - 1 | Pérez ZeledónPérez Zeledón |
| |
| 23 Oct 21 | r17 | Sporting San JoseSporting San | 2 - 0 | GuadalupeGuadalupe |
| |
| 27 Oct 21 | r18 | GuadalupeGuadalupe | 1 - 1 | CartaginésCartaginés |
| |
| 30 Oct 21 | r19 | GuadalupeGuadalupe | 2 - 0 | JicaralJicaral |
| |
| 21 Nov 21 | r20 | GreciaGrecia | 0 - 0 | GuadalupeGuadalupe |
| |
| 25 Nov 21 | r21  | AlajuelenseAlajuelense | 1 - 0 | GuadalupeGuadalupe |
| |
| 28 Nov 21 | r22 | GuadalupeGuadalupe | 0 - 5 | Santos de GuápilesSantos de Guá |
| |
| 13 Jan 22 | r01 | GuadalupeGuadalupe | 3 - 2 | CartaginésCartaginés |
| |
| 16 Jan 22 | r02 | AlajuelenseAlajuelense | 1 - 0 | GuadalupeGuadalupe |
| |
| 21 Jan 22 | r03 | Sporting San JoseSporting San | 2 - 2 | GuadalupeGuadalupe |
| |
| 04 Feb 22 | r04 | GuadalupeGuadalupe | 3 - 1 | AD San CarlosAD San Carlos |
| |
| 09 Feb 22 | r05 | GuadalupeGuadalupe | 3 - 1 | GreciaGrecia |
| |
| 12 Feb 22 | r06 | JicaralJicaral | 2 - 0 | GuadalupeGuadalupe |
| |
| 19 Feb 22 | r07 | GuadalupeGuadalupe | 4 - 1 | Santos de GuápilesSantos de Guá |
| |
| 27 Feb 22 | r08 | Deportivo SaprissaDeportivo Sap | 2 - 1 | GuadalupeGuadalupe |
| |
| 02 Mar 22 | r09 | Pérez ZeledónPérez Zeledón | 0 - 1 | GuadalupeGuadalupe |
| |
| 05 Mar 22 | r10 | GuadalupeGuadalupe | 1 - 1 | CS HeredianoCS Herediano |
| |
| 01 Apr 22 | r11 | GuanacastecaGuanacasteca | 1 - 2 | GuadalupeGuadalupe |
| |
| 08 Apr 22 | r12 | CartaginésCartaginés | 4 - 1 | GuadalupeGuadalupe |
| |
| 11 Apr 22 | r13 | GuadalupeGuadalupe | 0 - 2 | AlajuelenseAlajuelense |
| |
| 17 Apr 22 | r14 | GuadalupeGuadalupe | 4 - 2 | Sporting San JoseSporting San |
| |
| 20 Apr 22 | r15 | AD San CarlosAD San Carlos | 2 - 1 | GuadalupeGuadalupe |
| |
| 24 Apr 22 | r16 | GreciaGrecia | 3 - 2 | GuadalupeGuadalupe |
| |
| 28 Apr 22 | r17 | GuadalupeGuadalupe | 1 - 0 | JicaralJicaral |
| |
| 01 May 22 | r18 | Santos de GuápilesSantos de Guá | 6 - 0 | GuadalupeGuadalupe |
| |
| 05 May 22 | r19 | GuadalupeGuadalupe | 1 - 2 | Deportivo SaprissaDeportivo Sap |
| |
| 08 May 22 | r20 | GuadalupeGuadalupe | 2 - 2 | Pérez ZeledónPérez Zeledón |
| |
| 13 May 22 | r21 | CS HeredianoCS Herediano | 0 - 0 | GuadalupeGuadalupe |
| |
| 15 May 22 | r22 | GuadalupeGuadalupe | 0 - 0 | GuanacastecaGuanacasteca |
Team 2021-2022 Schedules
AD San Carlos
Alajuelense
Cartaginés
Deportivo Saprissa
Guadalupe
Herediano
Municipal Liberia
Pérez Zeledón
Puntarenas
Sporting San Jose
League Table
List
Poster
= Banner Image 
= Fanart Image