| 28 Jul 21 | r01    | Deportivo SaprissaDeportivo Sap | 3 - 0 | Santos de GuápilesSantos de Guá |
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| 31 Jul 21 | r02 | Pérez ZeledónPérez Zeledón | 0 - 3 | Deportivo SaprissaDeportivo Sap |
| |
| 09 Aug 21 | r03 | Deportivo SaprissaDeportivo Sap | 2 - 3 | CS HeredianoCS Herediano |
| |
| 11 Aug 21 | r04 | GuadalupeGuadalupe | 1 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 14 Aug 21 | r05 | Deportivo SaprissaDeportivo Sap | 1 - 0 | GreciaGrecia |
| |
| 18 Aug 21 | r06 | CartaginésCartaginés | 1 - 0 | Deportivo SaprissaDeportivo Sap |
| |
| 25 Aug 21 | r07  | Deportivo SaprissaDeportivo Sap | 4 - 0 | JicaralJicaral |
| |
| 29 Aug 21 | r08 | Deportivo SaprissaDeportivo Sap | 4 - 2 | AlajuelenseAlajuelense |
| |
| 08 Sep 21 | r09 | Sporting San JoseSporting San | 4 - 0 | Deportivo SaprissaDeportivo Sap |
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| 13 Sep 21 | r10 | AD San CarlosAD San Carlos | 1 - 0 | Deportivo SaprissaDeportivo Sap |
| |
| 17 Sep 21 | r11 | Deportivo SaprissaDeportivo Sap | 1 - 1 | GuanacastecaGuanacasteca |
| |
| 20 Sep 21 | r12 | Santos de GuápilesSantos de Guá | 3 - 3 | Deportivo SaprissaDeportivo Sap |
| |
| 27 Sep 21 | r13 | Deportivo SaprissaDeportivo Sap | 3 - 0 | Pérez ZeledónPérez Zeledón |
| |
| 04 Oct 21 | r14 | CS HeredianoCS Herediano | 2 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 15 Oct 21 | r15 | Deportivo SaprissaDeportivo Sap | 4 - 0 | GuadalupeGuadalupe |
| |
| 17 Oct 21 | r16 | GreciaGrecia | 1 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 24 Oct 21 | r17 | Deportivo SaprissaDeportivo Sap | 1 - 1 | CartaginésCartaginés |
| |
| 27 Oct 21 | r18 | JicaralJicaral | 0 - 0 | Deportivo SaprissaDeportivo Sap |
| |
| 31 Oct 21 | r19 | AlajuelenseAlajuelense | 0 - 0 | Deportivo SaprissaDeportivo Sap |
| |
| 21 Nov 21 | r20 | Deportivo SaprissaDeportivo Sap | 5 - 1 | Sporting San JoseSporting San |
| |
| 24 Nov 21 | r21 | Deportivo SaprissaDeportivo Sap | 3 - 0 | AD San CarlosAD San Carlos |
| |
| 28 Nov 21 | r22 | GuanacastecaGuanacasteca | 1 - 0 | Deportivo SaprissaDeportivo Sap |
| |
| 02 Dec 21 | r00 | Deportivo SaprissaDeportivo Sap | 3 - 0 | CS HeredianoCS Herediano |
| 06 Dec 21 | r00 | CS HeredianoCS Herediano | 1 - 0 | Deportivo SaprissaDeportivo Sap |
| 10 Dec 21 | r00 | Deportivo SaprissaDeportivo Sap | 2 - 1 | AlajuelenseAlajuelense |
| 12 Dec 21 | r00 | AlajuelenseAlajuelense | 0 - 0 | Deportivo SaprissaDeportivo Sap |
| |
| 17 Dec 21 | Final | Deportivo SaprissaDeportivo Sap | 0 - 1 | CS HeredianoCS Herediano |
| 19 Dec 21 | Final | CS HeredianoCS Herediano | 3 - 2 | Deportivo SaprissaDeportivo Sap |
| |
| 16 Jan 22 | r02 | Deportivo SaprissaDeportivo Sap | 1 - 2 | AD San CarlosAD San Carlos |
| |
| 23 Jan 22 | r03 | Deportivo SaprissaDeportivo Sap | 2 - 4 | CartaginésCartaginés |
| |
| 04 Feb 22 | r04 | CS HeredianoCS Herediano | 1 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 09 Feb 22 | r05 | Deportivo SaprissaDeportivo Sap | 1 - 2 | Santos de GuápilesSantos de Guá |
| |
| 13 Feb 22 | r06 | AlajuelenseAlajuelense | 0 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 20 Feb 22 | r07 | Pérez ZeledónPérez Zeledón | 0 - 0 | Deportivo SaprissaDeportivo Sap |
| |
| 27 Feb 22 | r08 | Deportivo SaprissaDeportivo Sap | 2 - 1 | GuadalupeGuadalupe |
| |
| 02 Mar 22 | r09 | JicaralJicaral | 1 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 06 Mar 22 | r10 | Sporting San JoseSporting San | 0 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 13 Mar 22 | r01 | GuanacastecaGuanacasteca | 1 - 2 | Deportivo SaprissaDeportivo Sap |
| |
| 02 Apr 22 | r11 | Deportivo SaprissaDeportivo Sap | 0 - 1 | GreciaGrecia |
| |
| 07 Apr 22 | r12 | Deportivo SaprissaDeportivo Sap | 2 - 2 | GuanacastecaGuanacasteca |
| |
| 10 Apr 22 | r13 | AD San CarlosAD San Carlos | 4 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 17 Apr 22 | r14 | CartaginésCartaginés | 3 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 21 Apr 22 | r15 | Deportivo SaprissaDeportivo Sap | 0 - 1 | CS HeredianoCS Herediano |
| |
| 24 Apr 22 | r16 | Santos de GuápilesSantos de Guá | 2 - 1 | Deportivo SaprissaDeportivo Sap |
| |
| 28 Apr 22 | r17 | Deportivo SaprissaDeportivo Sap | 2 - 0 | AlajuelenseAlajuelense |
| |
| 01 May 22 | r18 | Deportivo SaprissaDeportivo Sap | 2 - 1 | Pérez ZeledónPérez Zeledón |
| |
| 05 May 22 | r19 | GuadalupeGuadalupe | 1 - 2 | Deportivo SaprissaDeportivo Sap |
| |
| 08 May 22 | r20 | Deportivo SaprissaDeportivo Sap | 3 - 1 | JicaralJicaral |
| |
| 12 May 22 | r21 | Deportivo SaprissaDeportivo Sap | 1 - 0 | Sporting San JoseSporting San |
| |
| 16 May 22 | r22 | GreciaGrecia | 2 - 3 | Deportivo SaprissaDeportivo Sap |
| |
| 20 Jun 22 | r00 | Deportivo SaprissaDeportivo Sap | 1 - 1 | AlajuelenseAlajuelense |
| 23 Jun 22 | r00 | AlajuelenseAlajuelense | 3 - 1 | Deportivo SaprissaDeportivo Sap |
Team 2021-2022 Schedules
AD San Carlos
Alajuelense
Cartaginés
Deportivo Saprissa
Guadalupe
Herediano
Municipal Liberia
Pérez Zeledón
Puntarenas
Sporting San Jose
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