| 02 Mar 22 | r01  | FK OlimpikFK Olimpik | 0 - 0 | SurkhonSurkhon |
| 02 Mar 22 | r01 | NeftchiNeftchi | 1 - 0 | Kokand-1912Kokand-1912 |
| 03 Mar 22 | r01 | Dinamo SamarqandDinamo Samarq | 0 - 2 | PakhtakorPakhtakor |
| 03 Mar 22 | r01 | BunyodkorBunyodkor | 0 - 0 | SogdianaSogdiana |
| 03 Mar 22 | r01 | NavbahorNavbahor | 0 - 0 | NasafNasaf |
| 04 Mar 22 | r01 | QizilqumQizilqum | 2 - 0 | LokomotivLokomotiv |
| 04 Mar 22 | r01 | MetalourgMetalourg | 1 - 0 | OlmaliqOlmaliq |
| |
| 09 Mar 22 | r02 | NasafNasaf | 1 - 1 | MetalourgMetalourg |
| 09 Mar 22 | r02 | Kokand-1912Kokand-1912 | 1 - 0 | FK OlimpikFK Olimpik |
| 10 Mar 22 | r02 | SurkhonSurkhon | 1 - 2 | NavbahorNavbahor |
| 10 Mar 22 | r02 | PakhtakorPakhtakor | 1 - 0 | NeftchiNeftchi |
| 10 Mar 22 | r02 | QizilqumQizilqum | 3 - 1 | BunyodkorBunyodkor |
| 11 Mar 22 | r02 | LokomotivLokomotiv | 2 - 1 | OlmaliqOlmaliq |
| 11 Mar 22 | r02 | SogdianaSogdiana | 1 - 0 | Dinamo SamarqandDinamo Samarq |
| |
| 16 Mar 22 | r03 | FK OlimpikFK Olimpik | 1 - 1 | PakhtakorPakhtakor |
| 16 Mar 22 | r03 | MetalourgMetalourg | 0 - 0 | SurkhonSurkhon |
| 17 Mar 22 | r03 | Dinamo SamarqandDinamo Samarq | 0 - 0 | QizilqumQizilqum |
| 17 Mar 22 | r03 | NavbahorNavbahor | 2 - 0 | Kokand-1912Kokand-1912 |
| 18 Mar 22 | r03 | BunyodkorBunyodkor | 2 - 1 | LokomotivLokomotiv |
| 18 Mar 22 | r03 | NeftchiNeftchi | 1 - 2 | SogdianaSogdiana |
| |
| 31 Mar 22 | r04 | Kokand-1912Kokand-1912 | 1 - 0 | MetalourgMetalourg |
| 31 Mar 22 | r04 | BunyodkorBunyodkor | 2 - 1 | Dinamo SamarqandDinamo Samarq |
| 01 Apr 22 | r04 | QizilqumQizilqum | 3 - 0 | NeftchiNeftchi |
| 01 Apr 22 | r04 | SurkhonSurkhon | 1 - 2 | OlmaliqOlmaliq |
| 01 Apr 22 | r04 | PakhtakorPakhtakor | 1 - 0 | NavbahorNavbahor |
| 02 Apr 22 | r04 | LokomotivLokomotiv | 0 - 1 | NasafNasaf |
| 02 Apr 22 | r04 | SogdianaSogdiana | 1 - 1 | FK OlimpikFK Olimpik |
| |
| 25 Apr 22 | r05 | NeftchiNeftchi | 1 - 3 | BunyodkorBunyodkor |
| 25 Apr 22 | r05 | Dinamo SamarqandDinamo Samarq | 3 - 1 | LokomotivLokomotiv |
| 26 Apr 22 | r05 | NavbahorNavbahor | 1 - 2 | SogdianaSogdiana |
| 26 Apr 22 | r05 | FK OlimpikFK Olimpik | 0 - 1 | QizilqumQizilqum |
| 27 Apr 22 | r05 | OlmaliqOlmaliq | 3 - 0 | Kokand-1912Kokand-1912 |
| |
| 30 Apr 22 | r06 | BunyodkorBunyodkor | 1 - 5 | FK OlimpikFK Olimpik |
| 30 Apr 22 | r06 | Dinamo SamarqandDinamo Samarq | 1 - 1 | NeftchiNeftchi |
| 01 May 22 | r06 | LokomotivLokomotiv | 2 - 0 | SurkhonSurkhon |
| 01 May 22 | r06 | QizilqumQizilqum | 1 - 2 | NavbahorNavbahor |
| 01 May 22 | r06 | SogdianaSogdiana | 2 - 0 | MetalourgMetalourg |
| 02 May 22 | r06 | Kokand-1912Kokand-1912 | 0 - 1 | NasafNasaf |
| 02 May 22 | r06 | PakhtakorPakhtakor | 0 - 0 | OlmaliqOlmaliq |
| |
| 05 May 22 | r07 | NeftchiNeftchi | 0 - 1 | LokomotivLokomotiv |
| 05 May 22 | r07 | FK OlimpikFK Olimpik | 1 - 1 | Dinamo SamarqandDinamo Samarq |
| 06 May 22 | r07 | SurkhonSurkhon | 1 - 0 | Kokand-1912Kokand-1912 |
| 06 May 22 | r07 | MetalourgMetalourg | 1 - 1 | QizilqumQizilqum |
| 06 May 22 | r07 | NavbahorNavbahor | 2 - 1 | BunyodkorBunyodkor |
| 07 May 22 | r07 | OlmaliqOlmaliq | 3 - 2 | SogdianaSogdiana |
| 07 May 22 | r07 | NasafNasaf | 0 - 0 | PakhtakorPakhtakor |
| |
| 10 May 22 | r08 | BunyodkorBunyodkor | 1 - 1 | MetalourgMetalourg |
| 10 May 22 | r08 | NeftchiNeftchi | 0 - 0 | FK OlimpikFK Olimpik |
| 11 May 22 | r08 | LokomotivLokomotiv | 1 - 2 | Kokand-1912Kokand-1912 |
| 11 May 22 | r08 | QizilqumQizilqum | 1 - 4 | OlmaliqOlmaliq |
| 11 May 22 | r08 | Dinamo SamarqandDinamo Samarq | 0 - 1 | NavbahorNavbahor |
| 12 May 22 | r08 | PakhtakorPakhtakor | 2 - 2 | SurkhonSurkhon |
| 12 May 22 | r08 | SogdianaSogdiana | 1 - 2 | NasafNasaf |
| |
| 16 May 22 | r09 | FK OlimpikFK Olimpik | 0 - 3 | LokomotivLokomotiv |
| 16 May 22 | r09 | OlmaliqOlmaliq | 0 - 0 | BunyodkorBunyodkor |
| 17 May 22 | r09 | NavbahorNavbahor | 0 - 0 | NeftchiNeftchi |
| 17 May 22 | r09 | NasafNasaf | 5 - 0 | QizilqumQizilqum |
| 17 May 22 | r09 | MetalourgMetalourg | 2 - 1 | Dinamo SamarqandDinamo Samarq |
| 18 May 22 | r09 | SurkhonSurkhon | 2 - 4 | SogdianaSogdiana |
| 18 May 22 | r09 | Kokand-1912Kokand-1912 | 1 - 1 | PakhtakorPakhtakor |
| |
| 22 May 22 | r10 | NeftchiNeftchi | 3 - 0 | MetalourgMetalourg |
| 23 May 22 | r10 | LokomotivLokomotiv | 0 - 2 | PakhtakorPakhtakor |
| 23 May 22 | r10 | QizilqumQizilqum | 2 - 0 | SurkhonSurkhon |
| 23 May 22 | r10 | Dinamo SamarqandDinamo Samarq | 1 - 2 | OlmaliqOlmaliq |
| 24 May 22 | r10 | SogdianaSogdiana | 3 - 0 | Kokand-1912Kokand-1912 |
| 24 May 22 | r10 | BunyodkorBunyodkor | 1 - 4 | NasafNasaf |
| |
| 27 May 22 | r11 | NavbahorNavbahor | 2 - 0 | LokomotivLokomotiv |
| 27 May 22 | r11 | OlmaliqOlmaliq | 3 - 1 | NeftchiNeftchi |
| 28 May 22 | r11 | Kokand-1912Kokand-1912 | 1 - 3 | QizilqumQizilqum |
| 29 May 22 | r11 | SurkhonSurkhon | 1 - 0 | BunyodkorBunyodkor |
| |
| 17 Jun 22 | r12 | LokomotivLokomotiv | 0 - 1 | SogdianaSogdiana |
| 18 Jun 22 | r12 | Dinamo SamarqandDinamo Samarq | 1 - 3 | SurkhonSurkhon |
| 21 Jun 22 | r12 | NavbahorNavbahor | 0 - 0 | MetalourgMetalourg |
| 21 Jun 22 | r12 | BunyodkorBunyodkor | 1 - 1 | Kokand-1912Kokand-1912 |
| 22 Jun 22 | r12 | FK OlimpikFK Olimpik | 1 - 0 | OlmaliqOlmaliq |
| 22 Jun 22 | r12 | NeftchiNeftchi | 1 - 1 | NasafNasaf |
| 23 Jun 22 | r12 | QizilqumQizilqum | 0 - 2 | PakhtakorPakhtakor |
| |
| 26 Jun 22 | r11 | MetalourgMetalourg | 0 - 0 | FK OlimpikFK Olimpik |
| |
| 26 Jun 22 | r03 | OlmaliqOlmaliq | 2 - 2 | NasafNasaf |
| |
| 28 Jun 22 | r13 | Kokand-1912Kokand-1912 | 1 - 1 | Dinamo SamarqandDinamo Samarq |
| 29 Jun 22 | r13 | SurkhonSurkhon | 1 - 1 | NeftchiNeftchi |
| 29 Jun 22 | r13 | PakhtakorPakhtakor | 2 - 3 | BunyodkorBunyodkor |
| 30 Jun 22 | r13 | MetalourgMetalourg | 1 - 1 | LokomotivLokomotiv |
| 30 Jun 22 | r13 | NasafNasaf | 2 - 2 | FK OlimpikFK Olimpik |
| 01 Jul 22 | r13 | OlmaliqOlmaliq | 1 - 2 | NavbahorNavbahor |
| |
| 04 Jul 22 | r05 | MetalourgMetalourg | 0 - 2 | PakhtakorPakhtakor |
| 04 Jul 22 | r05 | NasafNasaf | 2 - 0 | SurkhonSurkhon |
| |
| 05 Jul 22 | r13 | SogdianaSogdiana | 0 - 3 | QizilqumQizilqum |
| |
| 05 Jul 22 | r10 | FK OlimpikFK Olimpik | 1 - 1 | NavbahorNavbahor |
| |
| 01 Aug 22 | r14 | SurkhonSurkhon | 0 - 5 | FK OlimpikFK Olimpik |
| 01 Aug 22 | r14 | PakhtakorPakhtakor | 3 - 2 | Dinamo SamarqandDinamo Samarq |
| 01 Aug 22 | r14 | SogdianaSogdiana | 2 - 0 | BunyodkorBunyodkor |
| 02 Aug 22 | r14 | Kokand-1912Kokand-1912 | 3 - 3 | NeftchiNeftchi |
| 02 Aug 22 | r14 | NasafNasaf | 0 - 1 | NavbahorNavbahor |
| 03 Aug 22 | r14 | OlmaliqOlmaliq | 0 - 1 | MetalourgMetalourg |
| 03 Aug 22 | r14 | LokomotivLokomotiv | 1 - 0 | QizilqumQizilqum |
| |
| 06 Aug 22 | r11 | PakhtakorPakhtakor | 2 - 2 | SogdianaSogdiana |
| 07 Aug 22 | r11 | Dinamo SamarqandDinamo Samarq | 0 - 4 | NasafNasaf |
| 07 Aug 22 | r11 | NasafNasaf | 0 - 4 | Dinamo SamarqandDinamo Samarq |
| |
| 10 Aug 22 | r15 | OlmaliqOlmaliq | 4 - 0 | LokomotivLokomotiv |
Team 2022 Schedules
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