| 03 Mar 26 | Qualifier    | Independiente PetroleroIndependiente | 0 - 0 | GuabiráGuabirá |
| 03 Mar 26 | Qualifier   | Montevideo City TorqueMontevideo Ci | 1 - 0 | Defensor SportingDefensor Spor |
| 04 Mar 26 | Qualifier | CobresalCobresal | 1 - 1 | Audax ItalianoAudax Italian |
| 04 Mar 26 | Qualifier | Academia Puerto CabelloAcademia Puer | 0 - 0 | MonagasMonagas |
| 04 Mar 26 | Qualifier | Alianza AtléticoAlianza Atlét | 2 - 0 | Deportivo GarcilasoDeportivo Gar |
| 04 Mar 26 | Qualifier | BloomingBlooming | 3 - 0 | San Antonio Bulo BuloSan Antonio B |
| 04 Mar 26 | Qualifier | CaracasCaracas | 0 - 0 | MetropolitanosMetropolitano |
| 05 Mar 26 | Qualifier | Atlético NacionalAtlético Naci | 1 - 3 | MillonariosMillonarios |
| 05 Mar 26 | Qualifier | Sportivo TrinidenseSportivo Trin | 0 - 1 | Club OlimpiaClub Olimpia |
| 05 Mar 26 | Qualifier | Universidad de ChileUniversidad d | 1 - 2 | PalestinoPalestino |
| 05 Mar 26 | Qualifier | Deportivo CuencaDeportivo Cue | 3 - 0 | Libertad FCLibertad FC |
| 05 Mar 26 | Qualifier | Boston RiverBoston River | 1 - 0 | Racing MontevideoRacing Montev |
| 05 Mar 26 | Qualifier | Club NacionalClub Nacional | 1 - 1 | RecoletaRecoleta |
| 06 Mar 26 | Qualifier | América de CaliAmérica de Ca | 2 - 1 | Atlético BucaramangaAtlético Buca |
| 06 Mar 26 | Qualifier | CiencianoCienciano | 1 - 1 | MelgarMelgar |
| 06 Mar 26 | Qualifier | OrenseOrense | 0 - 1 | MacaráMacará |
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