| 28 Nov 20 | r00  | APRAPR | 2 - 1 | GOR MahiaGOR Mahia |
| 28 Nov 20 | r00 | Forest RangersForest Ranger | 0 - 0 | BouenguidiBouenguidi |
| 28 Nov 20 | r00 | VipersVipers | 0 - 1 | Al-Hilal OmdurmanAl-Hilal Omdu |
| 28 Nov 20 | r00 | Jwaneng GalaxyJwaneng Galax | 4 - 0 | ZilimadjouZilimadjou |
| 28 Nov 20 | r00 | Costa do SolCosta do Sol | 1 - 2 | FC PlatinumFC Platinum |
| 28 Nov 20 | r00 | Les Buffles du BorgouLes Buffles d | 1 - 1 | MC AlgerMC Alger |
| 28 Nov 20 | r00 | MlandegeMlandege | 0 - 5 | CS SfaxienCS Sfaxien |
| 28 Nov 20 | r00 | Al-Ahly BenghaziAl-Ahly Bengh | 0 - 0 | Mekelle 70 EndertaMekelle 70 En |
| 29 Nov 20 | r00 | Young BuffaloesYoung Buffalo | 0 - 0 | Le Messager NgoziLe Messager N |
| 29 Nov 20 | r00 | PWD BamendaPWD Bamenda | 0 - 1 | Kaizer ChiefsKaizer Chiefs |
| 29 Nov 20 | r00 | BantuBantu | 0 - 1 | NkanaNkana |
| 29 Nov 20 | r00 | AS OtohôAS Otohô | 1 - 1 | Al-MerrikhAl-Merrikh |
| 29 Nov 20 | r00 | AkonanguiAkonangui | 0 - 1 | Atlético PetróleosAtlético Petr |
| 29 Nov 20 | r00 | Plateau UnitedPlateau Unite | 0 - 1 | Simba SCSimba SC |
| 29 Nov 20 | r00 | GazelleGazelle | P - P | Garde Républicaine DjibouGarde Républi |
| 29 Nov 20 | r00 | CR BelouizdadCR Belouizdad | 2 - 0 | Al-Nasr SCSCAl-Nasr SCSC |
| 29 Nov 20 | r00 | RahimoRahimo | 0 - 1 | EnyimbaEnyimba |
| 29 Nov 20 | r00 | NouadhibouNouadhibou | 1 - 1 | Asante KotokoAsante Kotoko |
| 29 Nov 20 | r00 | AS SONIDEPAS SONIDEP | 2 - 0 | Mogadishu CityMogadishu Cit |
| 29 Nov 20 | r00 | RC AbidjanRC Abidjan | 1 - 0 | ASC KaraASC Kara |
| 29 Nov 20 | r00 | Ashanti Golden BoysAshanti Golde | 1 - 2 | Stade MalienStade Malien |
| 29 Nov 20 | r00 | Gambia Armed Forces FCGambia Armed | 1 - 1 | TeunguethTeungueth |
| 04 Dec 20 | r00 | Al-MerrikhAl-Merrikh | 2 - 0 | AS OtohôAS Otohô |
| 04 Dec 20 | r00 | Garde Républicaine DjibouGarde Républi | 0 - 0 | GazelleGazelle |
| 05 Dec 20 | r00 | GOR MahiaGOR Mahia | 3 - 1 | APRAPR |
| 05 Dec 20 | r00 | FC PlatinumFC Platinum | 2 - 0 | Costa do SolCosta do Sol |
| 05 Dec 20 | r00 | Mekelle 70 EndertaMekelle 70 En | 0 - 0 | Al-Ahly BenghaziAl-Ahly Bengh |
| 05 Dec 20 | r00 | NkanaNkana | 0 - 0 | BantuBantu |
| 05 Dec 20 | r00 | Simba SCSimba SC | 0 - 0 | Plateau UnitedPlateau Unite |
| 05 Dec 20 | r00 | CS SfaxienCS Sfaxien | 3 - 1 | MlandegeMlandege |
| 05 Dec 20 | r00 | Mogadishu CityMogadishu Cit | 0 - 2 | AS SONIDEPAS SONIDEP |
| 05 Dec 20 | r00 | BouenguidiBouenguidi | 2 - 0 | Forest RangersForest Ranger |
| 05 Dec 20 | r00 | Atlético PetróleosAtlético Petr | 2 - 2 | AkonanguiAkonangui |
| 05 Dec 20 | r00 | Stade MalienStade Malien | 2 - 0 | Ashanti Golden BoysAshanti Golde |
| 05 Dec 20 | r00 | Kaizer ChiefsKaizer Chiefs | 0 - 0 | PWD BamendaPWD Bamenda |
| 06 Dec 20 | r00 | ZilimadjouZilimadjou | 1 - 1 | Jwaneng GalaxyJwaneng Galax |
| 06 Dec 20 | r00 | Al-Hilal OmdurmanAl-Hilal Omdu | 1 - 0 | VipersVipers |
| 06 Dec 20 | r00 | Le Messager NgoziLe Messager N | 1 - 1 | Young BuffaloesYoung Buffalo |
| 06 Dec 20 | r00 | EnyimbaEnyimba | 1 - 1 | RahimoRahimo |
| 06 Dec 20 | r00 | Asante KotokoAsante Kotoko | 2 - 0 | NouadhibouNouadhibou |
| 06 Dec 20 | r00 | ASC KaraASC Kara | 2 - 1 | RC AbidjanRC Abidjan |
| 06 Dec 20 | r00 | Al-Nasr SCSCAl-Nasr SCSC | 0 - 2 | CR BelouizdadCR Belouizdad |
| 06 Dec 20 | r00 | TeunguethTeungueth | 2 - 0 | Gambia Armed Forces FCGambia Armed |
| 19 Dec 20 | r00 | MC AlgerMC Alger | 5 - 1 | Les Buffles du BorgouLes Buffles d |
| 19 Dec 20 | r00 | MC AlgerMC Alger | 5 - 1 | Les Buffles du BorgouLes Buffles d |
| 22 Dec 20 | r00 | Young BuffaloesYoung Buffalo | 2 - 2 | Vita ClubVita Club |
| 22 Dec 20 | r00 | Jwaneng GalaxyJwaneng Galax | 0 - 2 | Mamelodi SundownsMamelodi Sund |
| 22 Dec 20 | r00 | TeunguethTeungueth | 0 - 0 | Raja CasablancaRaja Casablan |
| 23 Dec 20 | r00 | GazelleGazelle | 0 - 0 | Zamalek SCZamalek SC |
| 23 Dec 20 | r00 | Al-MerrikhAl-Merrikh | 3 - 0 | EnyimbaEnyimba |
| 23 Dec 20 | r00 | FC PlatinumFC Platinum | 1 - 0 | Simba SCSimba SC |
| 23 Dec 20 | r00 | NkanaNkana | 1 - 1 | Atlético PetróleosAtlético Petr |
| 23 Dec 20 | r00 | AS SONIDEPAS SONIDEP | 0 - 1 | Al Ahly SCAl Ahly SC |
| 23 Dec 20 | r00 | BouenguidiBouenguidi | 1 - 2 | TP MazembeTP Mazembe |
| 23 Dec 20 | r00 | Asante KotokoAsante Kotoko | 0 - 1 | Al-Hilal OmdurmanAl-Hilal Omdu |
| 23 Dec 20 | r00 | Stade MalienStade Malien | 1 - 0 | Wydad CasablancaWydad Casabla |
| 23 Dec 20 | r00 | Kaizer ChiefsKaizer Chiefs | 0 - 0 | Primeiro de AgostoPrimeiro de A |
| 23 Dec 20 | r00 | Al-Ahly BenghaziAl-Ahly Bengh | 0 - 0 | Espérance de TunisEspérance de |
| 23 Dec 20 | r00 | RC AbidjanRC Abidjan | 1 - 1 | Horoya ACHoroya AC |
| 26 Dec 20 | r00 | CR BelouizdadCR Belouizdad | 6 - 0 | GOR MahiaGOR Mahia |
| 28 Dec 20 | r00 | MC AlgerMC Alger | 2 - 0 | CS SfaxienCS Sfaxien |
| 05 Jan 21 | r00 | Zamalek SCZamalek SC | 0 - 0 | GazelleGazelle |
| 05 Jan 21 | r00 | Primeiro de AgostoPrimeiro de A | 0 - 1 | Kaizer ChiefsKaizer Chiefs |
| 05 Jan 21 | r00 | Mamelodi SundownsMamelodi Sund | 3 - 1 | Jwaneng GalaxyJwaneng Galax |
| 05 Jan 21 | r00 | Al Ahly SCAl Ahly SC | 4 - 0 | AS SONIDEPAS SONIDEP |
| 05 Jan 21 | r00 | Raja CasablancaRaja Casablan | 0 - 0 | TeunguethTeungueth |
| 06 Jan 21 | r00 | GOR MahiaGOR Mahia | 1 - 2 | CR BelouizdadCR Belouizdad |
| 06 Jan 21 | r00 | Al-Hilal OmdurmanAl-Hilal Omdu | 2 - 0 | Asante KotokoAsante Kotoko |
| 06 Jan 21 | r00 | TP MazembeTP Mazembe | 2 - 1 | BouenguidiBouenguidi |
| 06 Jan 21 | r00 | CS SfaxienCS Sfaxien | 1 - 0 | MC AlgerMC Alger |
| 06 Jan 21 | r00 | Simba SCSimba SC | 4 - 0 | FC PlatinumFC Platinum |
| 06 Jan 21 | r00 | Espérance de TunisEspérance de | 3 - 2 | Al-Ahly BenghaziAl-Ahly Bengh |
| 06 Jan 21 | r00 | EnyimbaEnyimba | 2 - 1 | Al-MerrikhAl-Merrikh |
| 06 Jan 21 | r00 | Vita ClubVita Club | 4 - 1 | Young BuffaloesYoung Buffalo |
| 06 Jan 21 | r00 | Wydad CasablancaWydad Casabla | 3 - 0 | Stade MalienStade Malien |
| 06 Jan 21 | r00 | Atlético PetróleosAtlético Petr | 1 - 0 | NkanaNkana |
| 06 Jan 21 | r00 | Horoya ACHoroya AC | 1 - 0 | RC AbidjanRC Abidjan |
| |
| 12 Feb 21 | r01   | Vita ClubVita Club | 0 - 1 | Simba SCSimba SC |
| 12 Feb 21 | r01 | Zamalek SCZamalek SC | 0 - 0 | MC AlgerMC Alger |
| 13 Feb 21 | r01 | TP MazembeTP Mazembe | 0 - 0 | CR BelouizdadCR Belouizdad |
| 13 Feb 21 | r01 | Espérance de TunisEspérance de | 2 - 1 | TeunguethTeungueth |
| 13 Feb 21 | r01 | Mamelodi SundownsMamelodi Sund | 2 - 0 | Al-Hilal OmdurmanAl-Hilal Omdu |
| 13 Feb 21 | r01 | Horoya ACHoroya AC | 2 - 0 | Atlético PetróleosAtlético Petr |
| 16 Feb 21 | r01 | Al Ahly SCAl Ahly SC | 3 - 0 | Al-MerrikhAl-Merrikh |
| |
| 23 Feb 21 | r02 | Simba SCSimba SC | 1 - 0 | Al Ahly SCAl Ahly SC |
| 23 Feb 21 | r02 | Al-MerrikhAl-Merrikh | 1 - 4 | Vita ClubVita Club |
| 23 Feb 21 | r02 | Atlético PetróleosAtlético Petr | 0 - 1 | Wydad CasablancaWydad Casabla |
| 23 Feb 21 | r02 | Kaizer ChiefsKaizer Chiefs | 0 - 0 | Horoya ACHoroya AC |
| 23 Feb 21 | r02 | TeunguethTeungueth | 0 - 0 | Zamalek SCZamalek SC |
| 23 Feb 21 | r02 | MC AlgerMC Alger | 1 - 1 | Espérance de TunisEspérance de |
| 24 Feb 21 | r02 | Al-Hilal OmdurmanAl-Hilal Omdu | 0 - 0 | TP MazembeTP Mazembe |
| 28 Feb 21 | r02 | CR BelouizdadCR Belouizdad | 1 - 5 | Mamelodi SundownsMamelodi Sund |
| |
| 28 Feb 21 | r01 | Wydad CasablancaWydad Casabla | 4 - 0 | Kaizer ChiefsKaizer Chiefs |
| |
| 05 Mar 21 | r03 | CR BelouizdadCR Belouizdad | 1 - 1 | Al-Hilal OmdurmanAl-Hilal Omdu |
| 06 Mar 21 | r03 | Al-MerrikhAl-Merrikh | 0 - 0 | Simba SCSimba SC |
| 06 Mar 21 | r03 | TP MazembeTP Mazembe | 1 - 2 | Mamelodi SundownsMamelodi Sund |
| 06 Mar 21 | r03 | Kaizer ChiefsKaizer Chiefs | 2 - 0 | Atlético PetróleosAtlético Petr |
| 06 Mar 21 | r03 | TeunguethTeungueth | 0 - 1 | MC AlgerMC Alger |
| 06 Mar 21 | r03 | Espérance de TunisEspérance de | 3 - 1 | Zamalek SCZamalek SC |
| 06 Mar 21 | r03 | Al Ahly SCAl Ahly SC | 2 - 2 | Vita ClubVita Club |
Team 2020-2021 Schedules
AS FAN
ASAS
ASC Kara
Associação Black Bulls
Côte d'Or
East End Lions
Elgeco Plus
Fundación Bata
Jamus
Lioli
Mangasport
Mlandege
Silver Strikers
Simba SC
Stade Malien
Tempête Mocaf
Zilimadjou
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