| 18 Apr 22 | r04     | PakhtakorPakhtakor | 0 - 3 | Al-Duhail SCAl-Duhail SC |
| 18 Apr 22 | r04 | Ahal FKAhal FK | 0 - 1 | Foolad FCFoolad FC |
| 18 Apr 22 | r04 | Mumbai CityMumbai City | 0 - 0 | Al JaziraAl Jazira |
| 18 Apr 22 | r04 | Shabab Al-Ahli DubaiShabab Al-Ahl | 8 - 2 | Al-GharafaAl-Gharafa |
| 18 Apr 22 | r04 | Al ShababAl Shabab | 3 - 0 | Al-Quwa Al-JawiyaAl-Quwa Al-Ja |
| 18 Apr 22 | r04 | SepahanSepahan | 1 - 1 | Al-TaawonAl-Taawon |
| 19 Apr 22 | r04 | Al-WehdatAl-Wehdat | 3 - 1 | Al-SaddAl-Sadd |
| 19 Apr 22 | r04 | Al-Rayyan SCAl-Rayyan SC | 3 - 1 | Al SharjahAl Sharjah |
| 19 Apr 22 | r04 | IstiklolIstiklol | 0 - 3 | Al HilalAl Hilal |
| 19 Apr 22 | r04 | Al-FaisalyAl-Faisaly | 0 - 0 | NasafNasaf |
| 24 Apr 22 | r04 | Guangzhou EvergrandeGuangzhou Eve | 0 - 5 | Ulsan Hyundai FCUlsan Hyundai |
| 24 Apr 22 | r04 | Jeonnam DragonsJeonnam Drago | 1 - 1 | Melbourne City FCMelbourne Cit |
| 24 Apr 22 | r04 | Urawa Red DiamondsUrawa Red Dia | 0 - 0 | Daegu FCDaegu FC |
| 24 Apr 22 | r04 | Johor Darul TazimJohor Darul T | 0 - 5 | Kawasaki FrontaleKawasaki Fron |
| 24 Apr 22 | r04 | Ceres–NegrosCeres–Negros | 1 - 3 | BG Pathum UnitedBG Pathum Uni |
| 24 Apr 22 | r04 | Home UnitedHome United | 3 - 2 | Shandong LunengShandong Lune |
| 25 Apr 22 | r04 | KitcheeKitchee | - | Shanghai East Asia FCShanghai East |
| 25 Apr 22 | r04 | Yokohama F MarinosYokohama F Ma | 3 - 0 | Sydney FCSydney FC |
| 25 Apr 22 | r04 | Hoang Anh Gia LaiHoang Anh Gia | 1 - 1 | Jeonbuk Hyundai MotorsJeonbuk Hyund |
| 25 Apr 22 | r04 | Chiangrai UnitedChiangrai Uni | 0 - 0 | Vissel KobeVissel Kobe |
Team 2022 Schedules
League Table
List
Poster
= Banner Image 
= Fanart Image 
= Timeline Details