| 23 Jul 21 | r01   | Stade Lausanne OuchyStade Lausann | 1 - 1 | FC WinterthurFC Winterthur |
| 25 Jul 21 | r01 | FC WilFC Wil | 2 - 3 | VaduzVaduz |
| 28 Jul 21 | r01 | SchaffhausenSchaffhausen | 1 - 1 | SC KriensSC Kriens |
| |
| 30 Jul 21 | r02 | FC WinterthurFC Winterthur | 3 - 1 | FC WilFC Wil |
| 31 Jul 21 | r02 | FC AarauFC Aarau | 2 - 0 | SchaffhausenSchaffhausen |
| 31 Jul 21 | r02 | SC KriensSC Kriens | 1 - 3 | ThunThun |
| 31 Jul 21 | r02 | Yverdon SportYverdon Sport | 1 - 3 | Stade Lausanne OuchyStade Lausann |
| 01 Aug 21 | r02 | VaduzVaduz | 1 - 2 | Neuchâtel XamaxNeuchâtel Xam |
| |
| 03 Aug 21 | r01 | ThunThun | 3 - 0 | Yverdon SportYverdon Sport |
| |
| 06 Aug 21 | r03 | Neuchâtel XamaxNeuchâtel Xam | 4 - 0 | SC KriensSC Kriens |
| 06 Aug 21 | r03 | ThunThun | 1 - 2 | FC AarauFC Aarau |
| 07 Aug 21 | r03 | FC WilFC Wil | 3 - 0 | Yverdon SportYverdon Sport |
| 08 Aug 21 | r03 | SchaffhausenSchaffhausen | 1 - 1 | FC WinterthurFC Winterthur |
| 08 Aug 21 | r03 | Stade Lausanne OuchyStade Lausann | 1 - 0 | VaduzVaduz |
| |
| 10 Aug 21 | r01 | Neuchâtel XamaxNeuchâtel Xam | 4 - 2 | FC AarauFC Aarau |
| |
| 20 Aug 21 | r04 | FC WinterthurFC Winterthur | 3 - 0 | ThunThun |
| 21 Aug 21 | r04 | FC AarauFC Aarau | 5 - 2 | Stade Lausanne OuchyStade Lausann |
| 21 Aug 21 | r04 | Yverdon SportYverdon Sport | 1 - 1 | Neuchâtel XamaxNeuchâtel Xam |
| 22 Aug 21 | r04 | SchaffhausenSchaffhausen | 1 - 1 | VaduzVaduz |
| |
| 27 Aug 21 | r05  | FC AarauFC Aarau | 1 - 3 | VaduzVaduz |
| 28 Aug 21 | r05 | SC KriensSC Kriens | 2 - 3 | FC WinterthurFC Winterthur |
| 29 Aug 21 | r05 | Neuchâtel XamaxNeuchâtel Xam | 3 - 0 | FC WilFC Wil |
| 29 Aug 21 | r05 | SchaffhausenSchaffhausen | 4 - 3 | Yverdon SportYverdon Sport |
| |
| 03 Sep 21 | r04 | SC KriensSC Kriens | 0 - 2 | FC WilFC Wil |
| |
| 10 Sep 21 | r06 | Stade Lausanne OuchyStade Lausann | 2 - 1 | SchaffhausenSchaffhausen |
| 10 Sep 21 | r06 | Yverdon SportYverdon Sport | 1 - 1 | FC AarauFC Aarau |
| 11 Sep 21 | r06 | FC WilFC Wil | 2 - 2 | ThunThun |
| 11 Sep 21 | r06 | FC WinterthurFC Winterthur | 2 - 1 | Neuchâtel XamaxNeuchâtel Xam |
| 12 Sep 21 | r06 | VaduzVaduz | 4 - 1 | SC KriensSC Kriens |
| |
| 14 Sep 21 | r05 | ThunThun | 1 - 0 | Stade Lausanne OuchyStade Lausann |
| |
| 21 Sep 21 | r07 | SchaffhausenSchaffhausen | 2 - 1 | ThunThun |
| 21 Sep 21 | r07 | VaduzVaduz | 2 - 0 | FC WinterthurFC Winterthur |
| 21 Sep 21 | r07 | FC AarauFC Aarau | 2 - 0 | FC WilFC Wil |
| 22 Sep 21 | r07 | SC KriensSC Kriens | 0 - 2 | Yverdon SportYverdon Sport |
| 22 Sep 21 | r07 | Neuchâtel XamaxNeuchâtel Xam | 3 - 1 | Stade Lausanne OuchyStade Lausann |
| |
| 24 Sep 21 | r08 | FC WilFC Wil | 2 - 0 | SchaffhausenSchaffhausen |
| 24 Sep 21 | r08 | FC WinterthurFC Winterthur | 0 - 0 | FC AarauFC Aarau |
| 25 Sep 21 | r08 | Yverdon SportYverdon Sport | 2 - 0 | VaduzVaduz |
| 25 Sep 21 | r08 | Stade Lausanne OuchyStade Lausann | 5 - 0 | SC KriensSC Kriens |
| 25 Sep 21 | r08 | ThunThun | 3 - 2 | Neuchâtel XamaxNeuchâtel Xam |
| |
| 01 Oct 21 | r09 | SchaffhausenSchaffhausen | 4 - 0 | Neuchâtel XamaxNeuchâtel Xam |
| 01 Oct 21 | r09 | VaduzVaduz | 1 - 3 | ThunThun |
| 02 Oct 21 | r09 | FC WilFC Wil | 2 - 3 | Stade Lausanne OuchyStade Lausann |
| 02 Oct 21 | r09 | FC WinterthurFC Winterthur | 1 - 0 | Yverdon SportYverdon Sport |
| 03 Oct 21 | r09 | FC AarauFC Aarau | 0 - 0 | SC KriensSC Kriens |
| |
| 15 Oct 21 | r10 | Neuchâtel XamaxNeuchâtel Xam | 0 - 2 | VaduzVaduz |
| 15 Oct 21 | r10 | Stade Lausanne OuchyStade Lausann | 0 - 2 | FC AarauFC Aarau |
| 15 Oct 21 | r10 | ThunThun | 0 - 2 | FC WinterthurFC Winterthur |
| 16 Oct 21 | r10 | SC KriensSC Kriens | 0 - 0 | SchaffhausenSchaffhausen |
| 16 Oct 21 | r10 | Yverdon SportYverdon Sport | 3 - 0 | FC WilFC Wil |
| |
| 22 Oct 21 | r11 | FC AarauFC Aarau | 0 - 2 | ThunThun |
| 22 Oct 21 | r11 | FC WilFC Wil | 2 - 1 | Neuchâtel XamaxNeuchâtel Xam |
| 23 Oct 21 | r11 | VaduzVaduz | 2 - 1 | SchaffhausenSchaffhausen |
| 23 Oct 21 | r11 | FC WinterthurFC Winterthur | 6 - 1 | SC KriensSC Kriens |
| |
| 29 Oct 21 | r12 | Neuchâtel XamaxNeuchâtel Xam | 1 - 1 | FC WinterthurFC Winterthur |
| 29 Oct 21 | r12 | VaduzVaduz | 2 - 1 | FC AarauFC Aarau |
| 30 Oct 21 | r12 | SC KriensSC Kriens | 1 - 0 | Stade Lausanne OuchyStade Lausann |
| 30 Oct 21 | r12 | Yverdon SportYverdon Sport | 1 - 0 | ThunThun |
| 30 Oct 21 | r12 | SchaffhausenSchaffhausen | 3 - 3 | FC WilFC Wil |
| 30 Oct 21 | r12 | SC KriensSC Kriens | 1 - 0 | Stade Lausanne OuchyStade Lausann |
| 30 Oct 21 | r12 | SchaffhausenSchaffhausen | 3 - 3 | FC WilFC Wil |
| 30 Oct 21 | r12 | Yverdon SportYverdon Sport | 1 - 0 | ThunThun |
| |
| 02 Nov 21 | r11 | Stade Lausanne OuchyStade Lausann | 0 - 0 | Yverdon SportYverdon Sport |
| |
| 05 Nov 21 | r13 | Neuchâtel XamaxNeuchâtel Xam | 0 - 3 | SchaffhausenSchaffhausen |
| 05 Nov 21 | r13 | ThunThun | 1 - 1 | VaduzVaduz |
| 05 Nov 21 | r13 | FC WinterthurFC Winterthur | 0 - 0 | Stade Lausanne OuchyStade Lausann |
| 06 Nov 21 | r13 | FC WilFC Wil | 4 - 0 | SC KriensSC Kriens |
| 06 Nov 21 | r13 | FC AarauFC Aarau | 1 - 0 | Yverdon SportYverdon Sport |
| |
| 19 Nov 21 | r14 | SchaffhausenSchaffhausen | 2 - 0 | FC AarauFC Aarau |
| 19 Nov 21 | r14 | Stade Lausanne OuchyStade Lausann | 2 - 0 | ThunThun |
| 19 Nov 21 | r14 | Yverdon SportYverdon Sport | 2 - 1 | FC WinterthurFC Winterthur |
| 20 Nov 21 | r14 | SC KriensSC Kriens | 0 - 1 | Neuchâtel XamaxNeuchâtel Xam |
| 20 Nov 21 | r14 | VaduzVaduz | 1 - 2 | FC WilFC Wil |
| |
| 26 Nov 21 | r15 | ThunThun | 3 - 1 | SC KriensSC Kriens |
| 26 Nov 21 | r15 | FC WinterthurFC Winterthur | 2 - 5 | SchaffhausenSchaffhausen |
| 26 Nov 21 | r15 | Neuchâtel XamaxNeuchâtel Xam | 2 - 1 | Yverdon SportYverdon Sport |
| 27 Nov 21 | r15 | VaduzVaduz | 2 - 1 | Stade Lausanne OuchyStade Lausann |
| 27 Nov 21 | r15 | FC WilFC Wil | 2 - 2 | FC AarauFC Aarau |
| |
| 03 Dec 21 | r16 | FC AarauFC Aarau | 2 - 0 | FC WinterthurFC Winterthur |
| 03 Dec 21 | r16 | Stade Lausanne OuchyStade Lausann | 0 - 0 | Neuchâtel XamaxNeuchâtel Xam |
| 03 Dec 21 | r16 | Yverdon SportYverdon Sport | 2 - 1 | SchaffhausenSchaffhausen |
| 04 Dec 21 | r16 | SC KriensSC Kriens | 1 - 3 | VaduzVaduz |
| 04 Dec 21 | r16 | ThunThun | 2 - 4 | FC WilFC Wil |
| |
| 10 Dec 21 | r17 | Neuchâtel XamaxNeuchâtel Xam | 1 - 4 | ThunThun |
| 10 Dec 21 | r17 | VaduzVaduz | 2 - 2 | Yverdon SportYverdon Sport |
| 11 Dec 21 | r17 | SchaffhausenSchaffhausen | 1 - 0 | Stade Lausanne OuchyStade Lausann |
| 11 Dec 21 | r17 | FC WilFC Wil | 3 - 5 | FC WinterthurFC Winterthur |
| 14 Dec 21 | r17 | SC KriensSC Kriens | 1 - 2 | FC AarauFC Aarau |
| |
| 17 Dec 21 | r18 | FC AarauFC Aarau | 1 - 0 | Neuchâtel XamaxNeuchâtel Xam |
| 17 Dec 21 | r18 | ThunThun | 2 - 2 | SchaffhausenSchaffhausen |
| 17 Dec 21 | r18 | Yverdon SportYverdon Sport | 2 - 0 | SC KriensSC Kriens |
| 18 Dec 21 | r18 | Stade Lausanne OuchyStade Lausann | 2 - 1 | FC WilFC Wil |
| 19 Dec 21 | r18 | FC WinterthurFC Winterthur | 2 - 3 | VaduzVaduz |
| |
| 28 Jan 22 | r19 | Yverdon SportYverdon Sport | 0 - 0 | Stade Lausanne OuchyStade Lausann |
| 28 Jan 22 | r19 | FC AarauFC Aarau | 1 - 1 | Neuchâtel XamaxNeuchâtel Xam |
| 30 Jan 22 | r19 | FC WilFC Wil | 4 - 4 | VaduzVaduz |
| 30 Jan 22 | r19 | FC WinterthurFC Winterthur | 3 - 0 | SC KriensSC Kriens |
| |
| 04 Feb 22 | r20 | Neuchâtel XamaxNeuchâtel Xam | 2 - 1 | SchaffhausenSchaffhausen |
| 04 Feb 22 | r20 | VaduzVaduz | 0 - 0 | FC WinterthurFC Winterthur |
| 05 Feb 22 | r20 | Stade Lausanne OuchyStade Lausann | 2 - 5 | FC AarauFC Aarau |
Team 2021-2022 Schedules
Aarau
Étoile Carouge
Kriens
Neuchâtel Xamax
Rapperswil-Jona
Stade Lausanne Ouchy
Stade Nyonnais
Wil
Winterthur
Yverdon Sport
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