| 19 Jul 21 | r01   | Dinamo Bucuresti Dinamo Bucure | 3 - 2 | FC VoluntariFC Voluntari |
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| 26 Jul 21 | r02 | FC U Craiova 1948FC U Craiova | 1 - 0 | Dinamo Bucuresti Dinamo Bucure |
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| 02 Aug 21 | r03 | Dinamo Bucuresti Dinamo Bucure | 3 - 1 | Academica ClinceniAcademica Cli |
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| 08 Aug 21 | r04  | Chindia TârgovișteChindia Târgo | 1 - 0 | Dinamo Bucuresti Dinamo Bucure |
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| 16 Aug 21 | r05 | Dinamo Bucuresti Dinamo Bucure | 0 - 1 | CS MioveniCS Mioveni |
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| 20 Aug 21 | r06 | Farul ConstantaFarul Constan | 3 - 0 | Dinamo Bucuresti Dinamo Bucure |
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| 28 Aug 21 | r07 | Dinamo Bucuresti Dinamo Bucure | 0 - 2 | Arges PitestiArges Pitesti |
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| 12 Sep 21 | r08 | Steaua BucurestiSteaua Bucure | 6 - 0 | Dinamo Bucuresti Dinamo Bucure |
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| 19 Sep 21 | r09 | Dinamo Bucuresti Dinamo Bucure | 1 - 2 | FC BotoșaniFC Botoșani |
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| 27 Sep 21 | r10 | Universitatea CraiovaUniversitatea | 5 - 0 | Dinamo Bucuresti Dinamo Bucure |
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| 02 Oct 21 | r11 | Dinamo Bucuresti Dinamo Bucure | 2 - 2 | Uta AradUta Arad |
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| 15 Oct 21 | r12 | Gaz Metan MediașGaz Metan Med | 2 - 1 | Dinamo Bucuresti Dinamo Bucure |
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| 23 Oct 21 | r13 | Dinamo Bucuresti Dinamo Bucure | 1 - 1 | Rapid BucurestiRapid Bucures |
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| 31 Oct 21 | r14 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ | 4 - 1 | Dinamo BucurestiDinamo Bucure |
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| 07 Nov 21 | r15 | Dinamo Bucuresti Dinamo Bucure | 0 - 3 | CFR Cluj-NapocaCFR Cluj-Napo |
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| 22 Nov 21 | r16 | FC VoluntariFC Voluntari | 2 - 1 | Dinamo Bucuresti Dinamo Bucure |
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| 26 Nov 21 | r17 | Dinamo Bucuresti Dinamo Bucure | 0 - 0 | FC U Craiova 1948FC U Craiova |
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| 03 Dec 21 | r18 | Academica ClinceniAcademica Cli | 1 - 0 | Dinamo Bucuresti Dinamo Bucure |
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| 13 Dec 21 | r19 | Dinamo Bucuresti Dinamo Bucure | 1 - 0 | Chindia TârgovișteChindia Târgo |
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| 16 Dec 21 | r20 | CS MioveniCS Mioveni | 2 - 1 | Dinamo Bucuresti Dinamo Bucure |
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| 20 Dec 21 | r21 | Dinamo Bucuresti Dinamo Bucure | 0 - 2 | Farul ConstantaFarul Constan |
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| 21 Jan 22 | r22 | Arges PitestiArges Pitesti | 2 - 1 | Dinamo Bucuresti Dinamo Bucure |
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| 30 Jan 22 | r23 | Dinamo Bucuresti Dinamo Bucure | 0 - 3 | Steaua BucurestiSteaua Bucure |
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| 07 Feb 22 | r24 | FC BotoșaniFC Botoșani | 4 - 0 | Dinamo Bucuresti Dinamo Bucure |
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| 10 Feb 22 | r25 | Dinamo Bucuresti Dinamo Bucure | 1 - 6 | Universitatea CraiovaUniversitatea |
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| 13 Feb 22 | r26 | Uta AradUta Arad | 0 - 0 | Dinamo Bucuresti Dinamo Bucure |
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| 18 Feb 22 | r27 | Dinamo Bucuresti Dinamo Bucure | 4 - 0 | Gaz Metan MediașGaz Metan Med |
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| 26 Feb 22 | r28 | Rapid BucurestiRapid Bucures | 1 - 1 | Dinamo Bucuresti Dinamo Bucure |
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| 01 Mar 22 | r29 | Dinamo Bucuresti Dinamo Bucure | 1 - 3 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
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| 06 Mar 22 | r30 | CFR Cluj-NapocaCFR Cluj-Napo | 4 - 1 | Dinamo Bucuresti Dinamo Bucure |
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| 13 Mar 22 | r01 | Rapid BucurestiRapid Bucures | 3 - 1 | Dinamo BucurestiDinamo Bucure |
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| 20 Mar 22 | r02 | Dinamo BucurestiDinamo Bucure | 0 - 0 | Sepsi OSK Sfântu GheorgheSepsi OSK Sfâ |
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| 01 Apr 22 | r03 | Chindia TârgovișteChindia Târgo | 0 - 2 | Dinamo BucurestiDinamo Bucure |
| |
| 08 Apr 22 | r04 | Dinamo BucurestiDinamo Bucure | 1 - 2 | FC U Craiova 1948FC U Craiova |
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| 15 Apr 22 | r05 | CS MioveniCS Mioveni | 2 - 0 | Dinamo BucurestiDinamo Bucure |
| |
| 22 Apr 22 | r06 | Gaz Metan MediașGaz Metan Med | 0 - 1 | Dinamo BucurestiDinamo Bucure |
| |
| 30 Apr 22 | r07 | Dinamo BucurestiDinamo Bucure | 5 - 1 | Academica ClinceniAcademica Cli |
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| 06 May 22 | r08 | FC BotoșaniFC Botoșani | 2 - 3 | Dinamo BucurestiDinamo Bucure |
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| 13 May 22 | r09 | Dinamo BucurestiDinamo Bucure | 1 - 1 | Uta AradUta Arad |
Team 2021-2022 Schedules
Argeș Pitești
Botoșani
CFR Cluj
Csíkszereda Miercurea Ciuc
Dinamo București
Farul Constanța
FCSB
Hermannstadt
Metaloglobus București
Oțelul Galați
Petrolul Ploiești
Rapid București
Unirea Slobozia
Universitatea Cluj
Universitatea Craiova
UTA Arad
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