| 24 Jul 21 | r01    | Lucerne Lucerne | 3 - 4 | Young BoysYoung Boys |
| 24 Jul 21 | r01 | FC Lausanne-SportFC Lausanne-S | 1 - 2 | St. GallenSt. Gallen |
| 25 Jul 21 | r01 | LuganoLugano | 0 - 2 | ZurichZurich |
| 25 Jul 21 | r01 | GrasshoppersGrasshoppers | 0 - 2 | FC BaselFC Basel |
| 25 Jul 21 | r01 | FC SionFC Sion | 1 - 2 | ServetteServette |
| |
| 31 Jul 21 | r02 | ZurichZurich | 3 - 1 | FC Lausanne-SportFC Lausanne-S |
| 31 Jul 21 | r02 | Young BoysYoung Boys | 0 - 0 | GrasshoppersGrasshoppers |
| 01 Aug 21 | r02 | St. GallenSt. Gallen | 2 - 2 | Lucerne Lucerne |
| 01 Aug 21 | r02 | FC BaselFC Basel | 6 - 1 | FC SionFC Sion |
| 01 Aug 21 | r02 | ServetteServette | 0 - 2 | LuganoLugano |
| |
| 07 Aug 21 | r03  | FC SionFC Sion | 1 - 0 | Young BoysYoung Boys |
| 07 Aug 21 | r03 | GrasshoppersGrasshoppers | 3 - 1 | FC Lausanne-SportFC Lausanne-S |
| 08 Aug 21 | r03 | LuganoLugano | 2 - 1 | St. GallenSt. Gallen |
| 08 Aug 21 | r03 | FC BaselFC Basel | 5 - 1 | ServetteServette |
| 08 Aug 21 | r03 | Lucerne Lucerne | 1 - 3 | ZurichZurich |
| |
| 21 Aug 21 | r04 | ZurichZurich | 2 - 1 | GrasshoppersGrasshoppers |
| 21 Aug 21 | r04 | St. GallenSt. Gallen | 1 - 1 | FC SionFC Sion |
| 22 Aug 21 | r04 | FC Lausanne-SportFC Lausanne-S | 2 - 2 | FC BaselFC Basel |
| 22 Aug 21 | r04 | ServetteServette | 4 - 1 | Lucerne Lucerne |
| |
| 28 Aug 21 | r05 | St. GallenSt. Gallen | 3 - 3 | ZurichZurich |
| 28 Aug 21 | r05 | FC SionFC Sion | 3 - 2 | LuganoLugano |
| 29 Aug 21 | r05 | Lucerne Lucerne | 1 - 1 | FC Lausanne-SportFC Lausanne-S |
| 29 Aug 21 | r05 | GrasshoppersGrasshoppers | 1 - 1 | ServetteServette |
| 29 Aug 21 | r05 | FC BaselFC Basel | 1 - 1 | Young BoysYoung Boys |
| |
| 11 Sep 21 | r06 | Lucerne Lucerne | 1 - 1 | GrasshoppersGrasshoppers |
| 11 Sep 21 | r06 | Young BoysYoung Boys | 4 - 0 | ZurichZurich |
| 12 Sep 21 | r06 | ServetteServette | 5 - 1 | St. GallenSt. Gallen |
| 12 Sep 21 | r06 | FC Lausanne-SportFC Lausanne-S | 1 - 1 | FC SionFC Sion |
| 12 Sep 21 | r06 | LuganoLugano | 1 - 1 | FC BaselFC Basel |
| |
| 21 Sep 21 | r07 | ZurichZurich | 2 - 2 | ServetteServette |
| 22 Sep 21 | r07 | FC Lausanne-SportFC Lausanne-S | 1 - 6 | Young BoysYoung Boys |
| 22 Sep 21 | r07 | St. GallenSt. Gallen | 0 - 2 | FC BaselFC Basel |
| 23 Sep 21 | r07 | LuganoLugano | 1 - 1 | GrasshoppersGrasshoppers |
| 23 Sep 21 | r07 | FC SionFC Sion | 1 - 1 | Lucerne Lucerne |
| |
| 25 Sep 21 | r08 | Young BoysYoung Boys | 2 - 1 | St. GallenSt. Gallen |
| 25 Sep 21 | r08 | ServetteServette | 1 - 1 | FC Lausanne-SportFC Lausanne-S |
| 26 Sep 21 | r08 | Lucerne Lucerne | 2 - 3 | LuganoLugano |
| 26 Sep 21 | r08 | GrasshoppersGrasshoppers | 3 - 1 | FC SionFC Sion |
| 26 Sep 21 | r08 | FC BaselFC Basel | 3 - 1 | ZurichZurich |
| |
| 02 Oct 21 | r09 | GrasshoppersGrasshoppers | 5 - 2 | St. GallenSt. Gallen |
| 02 Oct 21 | r09 | LuganoLugano | 2 - 0 | FC Lausanne-SportFC Lausanne-S |
| 03 Oct 21 | r09 | ZurichZurich | 6 - 2 | FC SionFC Sion |
| 03 Oct 21 | r09 | FC BaselFC Basel | 1 - 1 | Lucerne Lucerne |
| 03 Oct 21 | r09 | ServetteServette | 0 - 6 | Young BoysYoung Boys |
| |
| 16 Oct 21 | r10 | Young BoysYoung Boys | 1 - 1 | Lucerne Lucerne |
| 16 Oct 21 | r10 | ZurichZurich | 1 - 0 | LuganoLugano |
| 17 Oct 21 | r10 | FC Lausanne-SportFC Lausanne-S | 3 - 1 | GrasshoppersGrasshoppers |
| 17 Oct 21 | r10 | FC SionFC Sion | 0 - 1 | FC BaselFC Basel |
| 17 Oct 21 | r10 | St. GallenSt. Gallen | 2 - 1 | ServetteServette |
| |
| 23 Oct 21 | r11 | Young BoysYoung Boys | 3 - 2 | FC Lausanne-SportFC Lausanne-S |
| 23 Oct 21 | r11 | GrasshoppersGrasshoppers | 3 - 3 | ZurichZurich |
| 24 Oct 21 | r11 | Lucerne Lucerne | 2 - 0 | St. GallenSt. Gallen |
| 24 Oct 21 | r11 | FC BaselFC Basel | 2 - 0 | LuganoLugano |
| 24 Oct 21 | r11 | ServetteServette | 1 - 2 | FC SionFC Sion |
| |
| 30 Oct 21 | r12 | St. GallenSt. Gallen | 3 - 1 | Young BoysYoung Boys |
| 30 Oct 21 | r12 | ZurichZurich | 3 - 3 | FC BaselFC Basel |
| 31 Oct 21 | r12 | FC SionFC Sion | 1 - 3 | GrasshoppersGrasshoppers |
| 31 Oct 21 | r12 | FC Lausanne-SportFC Lausanne-S | 1 - 1 | Lucerne Lucerne |
| 31 Oct 21 | r12 | LuganoLugano | 2 - 1 | ServetteServette |
| |
| 06 Nov 21 | r13 | GrasshoppersGrasshoppers | 1 - 1 | Young BoysYoung Boys |
| 06 Nov 21 | r13 | Lucerne Lucerne | 0 - 1 | FC SionFC Sion |
| 07 Nov 21 | r13 | ServetteServette | 1 - 2 | ZurichZurich |
| 07 Nov 21 | r13 | FC BaselFC Basel | 0 - 1 | St. GallenSt. Gallen |
| 07 Nov 21 | r13 | FC Lausanne-SportFC Lausanne-S | 0 - 2 | LuganoLugano |
| |
| 20 Nov 21 | r14 | FC SionFC Sion | 0 - 1 | ZurichZurich |
| 21 Nov 21 | r14 | St. GallenSt. Gallen | 0 - 1 | FC Lausanne-SportFC Lausanne-S |
| 21 Nov 21 | r14 | LuganoLugano | 3 - 1 | Lucerne Lucerne |
| 21 Nov 21 | r14 | ServetteServette | 3 - 2 | GrasshoppersGrasshoppers |
| |
| 27 Nov 21 | r15 | GrasshoppersGrasshoppers | 0 - 1 | LuganoLugano |
| 27 Nov 21 | r15 | FC SionFC Sion | 3 - 1 | St. GallenSt. Gallen |
| 28 Nov 21 | r15 | ZurichZurich | 1 - 0 | Young BoysYoung Boys |
| 28 Nov 21 | r15 | FC Lausanne-SportFC Lausanne-S | 0 - 3 | ServetteServette |
| 28 Nov 21 | r15 | Lucerne Lucerne | 1 - 3 | FC BaselFC Basel |
| |
| 01 Dec 21 | r04 | Young BoysYoung Boys | 3 - 1 | LuganoLugano |
| |
| 04 Dec 21 | r16 | ZurichZurich | 4 - 0 | Lucerne Lucerne |
| 04 Dec 21 | r16 | Young BoysYoung Boys | 1 - 2 | ServetteServette |
| 05 Dec 21 | r16 | FC BaselFC Basel | 1 - 1 | FC Lausanne-SportFC Lausanne-S |
| 05 Dec 21 | r16 | LuganoLugano | 2 - 0 | FC SionFC Sion |
| 05 Dec 21 | r16 | St. GallenSt. Gallen | 0 - 4 | GrasshoppersGrasshoppers |
| |
| 11 Dec 21 | r17 | FC Lausanne-SportFC Lausanne-S | 1 - 3 | ZurichZurich |
| 11 Dec 21 | r17 | St. GallenSt. Gallen | 1 - 1 | LuganoLugano |
| 12 Dec 21 | r17 | Young BoysYoung Boys | 4 - 3 | FC SionFC Sion |
| 12 Dec 21 | r17 | GrasshoppersGrasshoppers | 1 - 1 | Lucerne Lucerne |
| 12 Dec 21 | r17 | ServetteServette | 2 - 2 | FC BaselFC Basel |
| |
| 15 Dec 21 | r14 | Young BoysYoung Boys | 1 - 1 | FC BaselFC Basel |
| |
| 18 Dec 21 | r18 | ZurichZurich | 3 - 1 | St. GallenSt. Gallen |
| 18 Dec 21 | r18 | Lucerne Lucerne | 0 - 2 | ServetteServette |
| 19 Dec 21 | r18 | LuganoLugano | 0 - 5 | Young BoysYoung Boys |
| 19 Dec 21 | r18 | FC BaselFC Basel | 2 - 2 | GrasshoppersGrasshoppers |
| 19 Dec 21 | r18 | FC SionFC Sion | 2 - 0 | FC Lausanne-SportFC Lausanne-S |
| |
| 29 Jan 22 | r19 | ZurichZurich | 1 - 0 | ServetteServette |
| 29 Jan 22 | r19 | Young BoysYoung Boys | 1 - 0 | LuganoLugano |
| 30 Jan 22 | r19 | FC Lausanne-SportFC Lausanne-S | 1 - 5 | St. GallenSt. Gallen |
| 30 Jan 22 | r19 | Lucerne Lucerne | 0 - 3 | FC BaselFC Basel |
| 30 Jan 22 | r19 | FC SionFC Sion | 2 - 0 | GrasshoppersGrasshoppers |
| |
| 05 Feb 22 | r20 | ServetteServette | 1 - 0 | FC Lausanne-SportFC Lausanne-S |
| 05 Feb 22 | r20 | GrasshoppersGrasshoppers | 1 - 3 | ZurichZurich |
| 06 Feb 22 | r20 | FC BaselFC Basel | 3 - 3 | FC SionFC Sion |
| 06 Feb 22 | r20 | LuganoLugano | 2 - 1 | Lucerne Lucerne |
| 06 Feb 22 | r20 | St. GallenSt. Gallen | 3 - 3 | Young BoysYoung Boys |
Team 2021-2022 Schedules
Basel
Grasshoppers
Lausanne-Sport
Lugano
Luzern
Servette
Sion
St. Gallen
Thun
Winterthur
Young Boys
Zürich
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