| 27 Aug 21 | r00  | ArsenalArsenal | 1 - 2 | Sheffield UnitedSheffield Uni |
| 27 Aug 21 | r00 | BirminghamBirmingham | 2 - 3 | BurnleyBurnley |
| 27 Aug 21 | r00 | BlackburnBlackburn | 1 - 1 | ChelseaChelsea |
| 27 Aug 21 | r00 | BoltonBolton | 2 - 2 | PrestonPreston |
| 27 Aug 21 | r00 | CardiffCardiff | 0 - 1 | TottenhamTottenham |
| 27 Aug 21 | r00 | EvertonEverton | 5 - 0 | Manchester UnitedManchester Un |
| 27 Aug 21 | r00 | Huddersfield TownHuddersfield | 1 - 2 | NewcastleNewcastle |
| 27 Aug 21 | r00 | Manchester CityManchester Ci | 2 - 1 | Aston VillaAston Villa |
| 27 Aug 21 | r00 | OldhamOldham | 0 - 0 | BradfordBradford |
| 27 Aug 21 | r00 | SunderlandSunderland | 3 - 0 | LiverpoolLiverpool |
| 27 Aug 21 | r00 | West BromWest Brom | 0 - 0 | MiddlesbroughMiddlesbrough |
| 29 Aug 21 | r00 | Aston VillaAston Villa | 2 - 1 | CardiffCardiff |
| 29 Aug 21 | r00 | BradfordBradford | 1 - 1 | BlackburnBlackburn |
| 29 Aug 21 | r00 | ChelseaChelsea | 1 - 2 | BirminghamBirmingham |
| 29 Aug 21 | r00 | Manchester UnitedManchester Un | 2 - 3 | West BromWest Brom |
| 29 Aug 21 | r00 | MiddlesbroughMiddlesbrough | 1 - 1 | OldhamOldham |
| 29 Aug 21 | r00 | PrestonPreston | 3 - 2 | ArsenalArsenal |
| 29 Aug 21 | r00 | Sheffield UnitedSheffield Uni | 1 - 1 | Huddersfield TownHuddersfield |
| 29 Aug 21 | r00 | TottenhamTottenham | 1 - 2 | BoltonBolton |
| 31 Aug 21 | r00 | LiverpoolLiverpool | 3 - 2 | Manchester CityManchester Ci |
| 31 Aug 21 | r00 | NewcastleNewcastle | 3 - 0 | EvertonEverton |
| 31 Aug 21 | r00 | SunderlandSunderland | 3 - 2 | BurnleyBurnley |
| 03 Sep 21 | r00 | Aston VillaAston Villa | 4 - 0 | Manchester CityManchester Ci |
| 03 Sep 21 | r00 | BradfordBradford | 3 - 0 | OldhamOldham |
| 03 Sep 21 | r00 | BurnleyBurnley | 3 - 1 | BirminghamBirmingham |
| 03 Sep 21 | r00 | ChelseaChelsea | 1 - 0 | BlackburnBlackburn |
| 03 Sep 21 | r00 | LiverpoolLiverpool | 2 - 1 | SunderlandSunderland |
| 03 Sep 21 | r00 | Manchester UnitedManchester Un | 2 - 1 | EvertonEverton |
| 03 Sep 21 | r00 | MiddlesbroughMiddlesbrough | 3 - 2 | West BromWest Brom |
| 03 Sep 21 | r00 | NewcastleNewcastle | 1 - 2 | Huddersfield TownHuddersfield |
| 03 Sep 21 | r00 | PrestonPreston | 3 - 1 | BoltonBolton |
| 03 Sep 21 | r00 | Sheffield UnitedSheffield Uni | 4 - 1 | ArsenalArsenal |
| 03 Sep 21 | r00 | TottenhamTottenham | 4 - 1 | CardiffCardiff |
| 05 Sep 21 | r00 | ArsenalArsenal | 1 - 0 | PrestonPreston |
| 05 Sep 21 | r00 | BirminghamBirmingham | 5 - 1 | ChelseaChelsea |
| 05 Sep 21 | r00 | BoltonBolton | 1 - 0 | TottenhamTottenham |
| 05 Sep 21 | r00 | BurnleyBurnley | 2 - 0 | SunderlandSunderland |
| 05 Sep 21 | r00 | CardiffCardiff | 0 - 4 | Aston VillaAston Villa |
| 05 Sep 21 | r00 | OldhamOldham | 0 - 1 | MiddlesbroughMiddlesbrough |
| 06 Sep 21 | r00 | Huddersfield TownHuddersfield | 1 - 1 | Sheffield UnitedSheffield Uni |
| 07 Sep 21 | r00 | EvertonEverton | 2 - 3 | NewcastleNewcastle |
| 07 Sep 21 | r00 | Manchester CityManchester Ci | 1 - 1 | LiverpoolLiverpool |
| 07 Sep 21 | r00 | West BromWest Brom | 0 - 0 | Manchester UnitedManchester Un |
| 10 Sep 21 | r00 | BoltonBolton | 3 - 3 | BradfordBradford |
| 10 Sep 21 | r00 | BurnleyBurnley | 2 - 0 | NewcastleNewcastle |
| 10 Sep 21 | r00 | CardiffCardiff | 0 - 1 | OldhamOldham |
| 10 Sep 21 | r00 | ChelseaChelsea | 0 - 0 | Manchester UnitedManchester Un |
| 10 Sep 21 | r00 | EvertonEverton | 2 - 1 | BirminghamBirmingham |
| 10 Sep 21 | r00 | Manchester CityManchester Ci | 2 - 0 | ArsenalArsenal |
| 10 Sep 21 | r00 | PrestonPreston | 1 - 0 | Aston VillaAston Villa |
| 10 Sep 21 | r00 | Sheffield UnitedSheffield Uni | 0 - 1 | LiverpoolLiverpool |
| 10 Sep 21 | r00 | SunderlandSunderland | 2 - 2 | Huddersfield TownHuddersfield |
| 10 Sep 21 | r00 | TottenhamTottenham | 2 - 4 | MiddlesbroughMiddlesbrough |
| 10 Sep 21 | r00 | West BromWest Brom | 0 - 2 | BlackburnBlackburn |
| 12 Sep 21 | r00 | Aston VillaAston Villa | 1 - 1 | BlackburnBlackburn |
| 17 Sep 21 | r00 | ArsenalArsenal | 0 - 1 | Manchester CityManchester Ci |
| 17 Sep 21 | r00 | Aston VillaAston Villa | 2 - 0 | PrestonPreston |
| 17 Sep 21 | r00 | BirminghamBirmingham | 1 - 1 | EvertonEverton |
| 17 Sep 21 | r00 | BlackburnBlackburn | 2 - 3 | West BromWest Brom |
| 17 Sep 21 | r00 | BradfordBradford | 4 - 3 | BoltonBolton |
| 17 Sep 21 | r00 | Huddersfield TownHuddersfield | 1 - 2 | SunderlandSunderland |
| 17 Sep 21 | r00 | LiverpoolLiverpool | 1 - 1 | Sheffield UnitedSheffield Uni |
| 17 Sep 21 | r00 | Manchester UnitedManchester Un | 0 - 0 | ChelseaChelsea |
| 17 Sep 21 | r00 | MiddlesbroughMiddlesbrough | 0 - 0 | TottenhamTottenham |
| 17 Sep 21 | r00 | NewcastleNewcastle | 2 - 1 | BurnleyBurnley |
| 17 Sep 21 | r00 | OldhamOldham | 2 - 1 | CardiffCardiff |
| 19 Sep 21 | r00 | BlackburnBlackburn | 3 - 1 | BradfordBradford |
| 24 Sep 21 | r00 | BoltonBolton | 3 - 1 | Huddersfield TownHuddersfield |
| 24 Sep 21 | r00 | BurnleyBurnley | 4 - 0 | BradfordBradford |
| 24 Sep 21 | r00 | CardiffCardiff | 3 - 1 | MiddlesbroughMiddlesbrough |
| 24 Sep 21 | r00 | ChelseaChelsea | 0 - 1 | LiverpoolLiverpool |
| 24 Sep 21 | r00 | EvertonEverton | 1 - 1 | ArsenalArsenal |
| 24 Sep 21 | r00 | Manchester CityManchester Ci | 1 - 1 | BlackburnBlackburn |
| 24 Sep 21 | r00 | PrestonPreston | 3 - 2 | Manchester UnitedManchester Un |
| 24 Sep 21 | r00 | Sheffield UnitedSheffield Uni | 1 - 1 | NewcastleNewcastle |
| 24 Sep 21 | r00 | SunderlandSunderland | 2 - 1 | BirminghamBirmingham |
| 24 Sep 21 | r00 | TottenhamTottenham | 3 - 1 | Aston VillaAston Villa |
| 24 Sep 21 | r00 | West BromWest Brom | 0 - 1 | OldhamOldham |
| 01 Oct 21 | r00 | ArsenalArsenal | 1 - 0 | EvertonEverton |
| 01 Oct 21 | r00 | Aston VillaAston Villa | 2 - 1 | TottenhamTottenham |
| 01 Oct 21 | r00 | BirminghamBirmingham | 1 - 0 | SunderlandSunderland |
| 01 Oct 21 | r00 | BlackburnBlackburn | 3 - 1 | Manchester CityManchester Ci |
| 01 Oct 21 | r00 | BradfordBradford | 0 - 4 | BurnleyBurnley |
| 01 Oct 21 | r00 | Huddersfield TownHuddersfield | 3 - 0 | BoltonBolton |
| 01 Oct 21 | r00 | LiverpoolLiverpool | 1 - 1 | ChelseaChelsea |
| 01 Oct 21 | r00 | Manchester UnitedManchester Un | 1 - 1 | PrestonPreston |
| 01 Oct 21 | r00 | MiddlesbroughMiddlesbrough | 0 - 0 | CardiffCardiff |
| 01 Oct 21 | r00 | NewcastleNewcastle | 2 - 1 | Sheffield UnitedSheffield Uni |
| 01 Oct 21 | r00 | OldhamOldham | 1 - 0 | West BromWest Brom |
| 08 Oct 21 | r00 | BirminghamBirmingham | 0 - 2 | Huddersfield TownHuddersfield |
| 08 Oct 21 | r00 | BradfordBradford | 0 - 2 | MiddlesbroughMiddlesbrough |
| 08 Oct 21 | r00 | BurnleyBurnley | 2 - 1 | Sheffield UnitedSheffield Uni |
| 08 Oct 21 | r00 | CardiffCardiff | 1 - 2 | BoltonBolton |
| 08 Oct 21 | r00 | ChelseaChelsea | 1 - 1 | NewcastleNewcastle |
| 08 Oct 21 | r00 | EvertonEverton | 2 - 0 | BlackburnBlackburn |
| 08 Oct 21 | r00 | Manchester CityManchester Ci | 2 - 1 | OldhamOldham |
| 08 Oct 21 | r00 | PrestonPreston | 1 - 1 | LiverpoolLiverpool |
| 08 Oct 21 | r00 | SunderlandSunderland | 1 - 0 | ArsenalArsenal |
| 08 Oct 21 | r00 | TottenhamTottenham | 2 - 2 | Manchester UnitedManchester Un |
| 08 Oct 21 | r00 | West BromWest Brom | 0 - 1 | Aston VillaAston Villa |
Team 1921-1922 Schedules
Aberdare Athletic FC
Accrington FC
Bootle FC
Burton Swifts
Burton United FC
Durham City AFC
Glossop North End AFC
Hereford United FC
Leeds City FC
Loughborough FC
Middlesbrough Ironopolis FC
Nelson FC
New Brighton AFC
New Brighton Tower FC
Rotherham Town FC
Scarborough FC
Thames AFC
Wigan Borough FC
Wimbledon FC
Workington AFC
League Table
List
Poster
= TV Listing 
= Event Thumb 
= Banner Image 
= Fanart Image 
= Timeline Details