| 27 Mar 16 | r01        | West Coast EaglesWest Coast Ea | 166 - 102 | Brisbane LionsBrisbane Lion |
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| 02 Apr 16 | r02        | Brisbane LionsBrisbane Lion | 83 - 117 | North Melbourne Football North Melbour |
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| 10 Apr 16 | r03        | Geelong Football ClubGeelong Footb | 125 - 56 | Brisbane LionsBrisbane Lion |
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| 16 Apr 16 | r04        | Brisbane LionsBrisbane Lion | 107 - 94 | Gold Coast Football ClubGold Coast Fo |
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| 23 Apr 16 | r05        | Western BulldogsWestern Bulld | 120 - 67 | Brisbane LionsBrisbane Lion |
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| 01 May 16 | r06        | Brisbane LionsBrisbane Lion | 94 - 97 | Sydney SwansSydney Swans |
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| 08 May 16 | r07        | Port Adelaide Football ClPort Adelaide | 136 - 59 | Brisbane LionsBrisbane Lion |
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| 14 May 16 | r08        | Brisbane LionsBrisbane Lion | 65 - 143 | Collingwood Football ClubCollingwood F |
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| 22 May 16 | r09        | Melbourne Football ClubMelbourne Foo | 131 - 68 | Brisbane LionsBrisbane Lion |
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| 28 May 16 | r10        | Brisbane LionsBrisbane Lion | 87 - 135 | Hawthorn Football ClubHawthorn Foot |
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| 04 Jun 16 | r11        | Carlton Football ClubCarlton Footb | 102 - 64 | Brisbane LionsBrisbane Lion |
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| 11 Jun 16 | r12        | Brisbane LionsBrisbane Lion | 64 - 147 | Fremantle Football ClubFremantle Foo |
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| 18 Jun 16 | r13        | Brisbane LionsBrisbane Lion | 82 - 131 | West Coast EaglesWest Coast Ea |
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| 25 Jun 16 | r14        | Richmond Football ClubRichmond Foot | 117 - 75 | Brisbane LionsBrisbane Lion |
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| 09 Jul 16 | r00        | Gold Coast Football ClubGold Coast Fo | 22 - 17 | Brisbane LionsBrisbane Lion |
| 17 Jul 16 | r00        | Brisbane LionsBrisbane Lion | 9 - 22 | Greater Western Sydney GiGreater Weste |
| 24 Jul 16 | r00        | Essendon Football ClubEssendon Foot | 12 - 20 | Brisbane LionsBrisbane Lion |
| 30 Jul 16 | r00        | Brisbane LionsBrisbane Lion | 11 - 25 | Port Adelaide Football ClPort Adelaide |
| 06 Aug 16 | r00        | Adelaide Football ClubAdelaide Foot | 27 - 6 | Brisbane LionsBrisbane Lion |
| 13 Aug 16 | r00        | Brisbane LionsBrisbane Lion | 15 - 13 | Carlton Football ClubCarlton Footb |
| 21 Aug 16 | r00        | Brisbane LionsBrisbane Lion | 10 - 19 | Geelong Football ClubGeelong Footb |
| 28 Aug 16 | r23        | St Kilda Football ClubSt Kilda Foot | 161 - 103 | Brisbane LionsBrisbane Lion |