

Team 2010 Scheduals| 13 Mar |
r01 ![]() ![]() | Canterbury Bankstown BullCanterbury Ba | 16 - 20 | Newcastle Knights Newcastle Kni |
| 20 Mar |
r02 ![]() ![]() | Newcastle Knights Newcastle Kni | 14 - 20 | Melbourne StormMelbourne Sto |
| 27 Mar |
r03 ![]() ![]() | Manly Sea EaglesManly Sea Eag | 36 - 12 | Newcastle Knights Newcastle Kni |
| 05 Apr |
r04 ![]() ![]() | Newcastle Knights Newcastle Kni | 30 - 34 | Penrith PanthersPenrith Panth |
| 10 Apr |
r05 ![]() ![]() | South Sydney RabbitohsSouth Sydney | 28 - 10 | Newcastle Knights Newcastle Kni |
| 17 Apr |
r06 ![]() ![]() | Newcastle Knights Newcastle Kni | 36 - 18 | North Queensland Cowboys North Queensl |
| 24 Apr |
r07 ![]() ![]() | Cronulla SharksCronulla Shar | 26 - 6 | Newcastle Knights Newcastle Kni |
| 30 Apr |
r08 ![]() ![]() | Brisbane BroncosBrisbane Bron | 22 - 30 | Newcastle Knights Newcastle Kni |
| 09 May |
r09 ![]() ![]() | Newcastle Knights Newcastle Kni | 36 - 38 | Gold Coast TitansGold Coast Ti |
| 15 May |
r10 ![]() ![]() | Sydney RoostersSydney Rooste | 18 - 34 | Newcastle Knights Newcastle Kni |
| 21 May |
r11 ![]() ![]() | Newcastle Knights Newcastle Kni | 6 - 23 | Wests TigersWests Tigers |
| 05 Jun |
r13 ![]() ![]() | Penrith PanthersPenrith Panth | 28 - 10 | Newcastle Knights Newcastle Kni |
| 13 Jun |
r14 ![]() ![]() | Newcastle Knights Newcastle Kni | 24 - 32 | New Zealand WarriorsNew Zealand W |
| 21 Jun |
r15 ![]() ![]() | Newcastle Knights Newcastle Kni | 6 - 4 | Parramatta EelsParramatta Ee |
| 27 Jun |
r16 ![]() ![]() | Gold Coast TitansGold Coast Ti | 16 - 24 | Newcastle Knights Newcastle Kni |
| 11 Jul |
r18 ![]() ![]() | Newcastle Knights Newcastle Kni | 21 - 10 | Cronulla SharksCronulla Shar |
| 18 Jul |
r19 ![]() ![]() | Canberra RaidersCanberra Raid | 52 - 18 | Newcastle Knights Newcastle Kni |
| 24 Jul |
r20 ![]() ![]() | North Queensland Cowboys North Queensl | 28 - 24 | Newcastle Knights Newcastle Kni |
| 02 Aug |
r21 ![]() ![]() | Newcastle Knights Newcastle Kni | 32 - 14 | Manly Sea EaglesManly Sea Eag |
| 08 Aug |
r22 ![]() ![]() | Newcastle Knights Newcastle Kni | 30 - 6 | Canterbury Bankstown BullCanterbury Ba |
| 15 Aug |
r23 ![]() ![]() | New Zealand WarriorsNew Zealand W | 22 - 10 | Newcastle Knights Newcastle Kni |
| 20 Aug |
r24 ![]() ![]() | Newcastle Knights Newcastle Kni | 44 - 18 | Brisbane BroncosBrisbane Bron |
| 28 Aug |
r25 ![]() ![]() | Newcastle Knights Newcastle Kni | 18 - 26 | St. George Illawara DragoSt. George Il |
| 05 Sep |
r26 ![]() ![]() | Melbourne StormMelbourne Sto | 34 - 4 | Newcastle Knights Newcastle Kni |