| 12 Mar 10 | r01        | Parramatta EelsParramatta Ee | 12 - 18 | St. George Illawara DragoSt. George Il |
| 12 Mar 10 | r01        | Brisbane BroncosBrisbane Bron | 30 - 24 | North Queensland Cowboys North Queensl |
| 13 Mar 10 | r01        | Canterbury Bankstown BullCanterbury Ba | 16 - 20 | Newcastle Knights Newcastle Kni |
| 13 Mar 10 | r01        | Cronulla SharksCronulla Shar | 10 - 14 | Melbourne StormMelbourne Sto |
| 13 Mar 10 | r01        | Penrith PanthersPenrith Panth | 34 - 16 | Canberra RaidersCanberra Raid |
| 14 Mar 10 | r01        | Gold Coast TitansGold Coast Ti | 24 - 18 | New Zealand WarriorsNew Zealand W |
| 14 Mar 10 | r01        | South Sydney RabbitohsSouth Sydney | 10 - 36 | Sydney RoostersSydney Rooste |
| 15 Mar 10 | r01        | Wests TigersWests Tigers | 26 - 22 | Manly Sea EaglesManly Sea Eag |
| |
| 19 Mar 10 | r02        | St. George Illawara DragoSt. George Il | 26 - 6 | Canterbury Bankstown BullCanterbury Ba |
| 19 Mar 10 | r02        | South Sydney RabbitohsSouth Sydney | 18 - 19 | Gold Coast TitansGold Coast Ti |
| 20 Mar 10 | r02        | New Zealand WarriorsNew Zealand W | 30 - 16 | Cronulla SharksCronulla Shar |
| 20 Mar 10 | r02        | Newcastle Knights Newcastle Kni | 14 - 20 | Melbourne StormMelbourne Sto |
| 20 Mar 10 | r02        | North Queensland Cowboys North Queensl | 28 - 20 | Penrith PanthersPenrith Panth |
| 21 Mar 10 | r02        | Parramatta EelsParramatta Ee | 24 - 20 | Manly Sea EaglesManly Sea Eag |
| 21 Mar 10 | r02        | Sydney RoostersSydney Rooste | 44 - 32 | Wests TigersWests Tigers |
| 22 Mar 10 | r02        | Canberra RaidersCanberra Raid | 22 - 14 | Brisbane BroncosBrisbane Bron |
| |
| 26 Mar 10 | r03        | Wests TigersWests Tigers | 23 - 12 | Parramatta EelsParramatta Ee |
| 26 Mar 10 | r03        | St. George Illawara DragoSt. George Il | 33 - 8 | North Queensland Cowboys North Queensl |
| 27 Mar 10 | r03        | Penrith PanthersPenrith Panth | 10 - 16 | Melbourne StormMelbourne Sto |
| 27 Mar 10 | r03        | Manly Sea EaglesManly Sea Eag | 36 - 12 | Newcastle Knights Newcastle Kni |
| 27 Mar 10 | r03        | Gold Coast TitansGold Coast Ti | 24 - 4 | Canberra RaidersCanberra Raid |
| 28 Mar 10 | r03        | Brisbane BroncosBrisbane Bron | 16 - 48 | New Zealand WarriorsNew Zealand W |
| 28 Mar 10 | r03        | Canterbury Bankstown BullCanterbury Ba | 60 - 14 | Sydney RoostersSydney Rooste |
| 29 Mar 10 | r03        | Cronulla SharksCronulla Shar | 8 - 30 | South Sydney RabbitohsSouth Sydney |
| |
| 02 Apr 10 | r04        | Melbourne StormMelbourne Sto | 17 - 4 | St. George Illawara DragoSt. George Il |
| 02 Apr 10 | r04        | Sydney RoostersSydney Rooste | 25 - 6 | Brisbane BroncosBrisbane Bron |
| 03 Apr 10 | r04        | Cronulla SharksCronulla Shar | 11 - 0 | Parramatta EelsParramatta Ee |
| 03 Apr 10 | r04        | North Queensland Cowboys North Queensl | 32 - 18 | Gold Coast TitansGold Coast Ti |
| 04 Apr 10 | r04        | New Zealand WarriorsNew Zealand W | 6 - 14 | Manly Sea EaglesManly Sea Eag |
| 04 Apr 10 | r04        | Canberra RaidersCanberra Raid | 22 - 35 | Wests TigersWests Tigers |
| 05 Apr 10 | r04        | Newcastle Knights Newcastle Kni | 30 - 34 | Penrith PanthersPenrith Panth |
| 05 Apr 10 | r04        | South Sydney RabbitohsSouth Sydney | 38 - 16 | Canterbury Bankstown BullCanterbury Ba |
| |
| 09 Apr 10 | r05        | Gold Coast TitansGold Coast Ti | 20 - 16 | Melbourne StormMelbourne Sto |
| 09 Apr 10 | r05        | St. George Illawara DragoSt. George Il | 34 - 16 | Brisbane BroncosBrisbane Bron |
| 10 Apr 10 | r05        | South Sydney RabbitohsSouth Sydney | 28 - 10 | Newcastle Knights Newcastle Kni |
| 10 Apr 10 | r05        | Canterbury Bankstown BullCanterbury Ba | 24 - 30 | New Zealand WarriorsNew Zealand W |
| 10 Apr 10 | r05        | North Queensland Cowboys North Queensl | 16 - 23 | Wests TigersWests Tigers |
| 11 Apr 10 | r05        | Manly Sea EaglesManly Sea Eag | 40 - 12 | Cronulla SharksCronulla Shar |
| 11 Apr 10 | r05        | Penrith PanthersPenrith Panth | 28 - 6 | Sydney RoostersSydney Rooste |
| 12 Apr 10 | r05        | Parramatta EelsParramatta Ee | 14 - 24 | Canberra RaidersCanberra Raid |
| |
| 16 Apr 10 | r06        | Gold Coast TitansGold Coast Ti | 6 - 19 | St. George Illawara DragoSt. George Il |
| 16 Apr 10 | r06        | Wests TigersWests Tigers | 4 - 24 | Canterbury Bankstown BullCanterbury Ba |
| 17 Apr 10 | r06        | Newcastle Knights Newcastle Kni | 36 - 18 | North Queensland Cowboys North Queensl |
| 17 Apr 10 | r06        | Sydney RoostersSydney Rooste | 36 - 6 | Canberra RaidersCanberra Raid |
| 18 Apr 10 | r06        | New Zealand WarriorsNew Zealand W | 12 - 40 | Penrith PanthersPenrith Panth |
| 18 Apr 10 | r06        | Brisbane BroncosBrisbane Bron | 44 - 16 | Cronulla SharksCronulla Shar |
| 18 Apr 10 | r06        | Parramatta EelsParramatta Ee | 22 - 8 | South Sydney RabbitohsSouth Sydney |
| 19 Apr 10 | r06        | Melbourne StormMelbourne Sto | 16 - 18 | Manly Sea EaglesManly Sea Eag |
| |
| 23 Apr 10 | r07        | Canterbury Bankstown BullCanterbury Ba | 36 - 18 | Brisbane BroncosBrisbane Bron |
| 23 Apr 10 | r07        | North Queensland Cowboys North Queensl | 18 - 24 | Parramatta EelsParramatta Ee |
| 24 Apr 10 | r07        | Penrith PanthersPenrith Panth | 26 - 18 | Wests TigersWests Tigers |
| 24 Apr 10 | r07        | Cronulla SharksCronulla Shar | 26 - 6 | Newcastle Knights Newcastle Kni |
| 25 Apr 10 | r07        | Canberra RaidersCanberra Raid | 24 - 26 | South Sydney RabbitohsSouth Sydney |
| 25 Apr 10 | r07        | St. George Illawara DragoSt. George Il | 28 - 6 | Sydney RoostersSydney Rooste |
| 25 Apr 10 | r07        | Melbourne StormMelbourne Sto | 40 - 6 | New Zealand WarriorsNew Zealand W |
| 26 Apr 10 | r07        | Manly Sea EaglesManly Sea Eag | 22 - 24 | Gold Coast TitansGold Coast Ti |
| |
| 30 Apr 10 | r08        | Brisbane BroncosBrisbane Bron | 22 - 30 | Newcastle Knights Newcastle Kni |
| 30 Apr 10 | r08        | Parramatta EelsParramatta Ee | 26 - 10 | Canterbury Bankstown BullCanterbury Ba |
| 01 May 10 | r08        | New Zealand WarriorsNew Zealand W | 16 - 23 | Canberra RaidersCanberra Raid |
| 01 May 10 | r08        | Gold Coast TitansGold Coast Ti | 38 - 24 | Penrith PanthersPenrith Panth |
| 01 May 10 | r08        | North Queensland Cowboys North Queensl | 6 - 34 | Melbourne StormMelbourne Sto |
| 01 May 10 | r08        | St. George Illawara DragoSt. George Il | 38 - 0 | Cronulla SharksCronulla Shar |
| 02 May 10 | r08        | Wests TigersWests Tigers | 8 - 12 | Sydney RoostersSydney Rooste |
| 02 May 10 | r08        | South Sydney RabbitohsSouth Sydney | 22 - 30 | Manly Sea EaglesManly Sea Eag |
| |
| 08 May 10 | r09        | Manly Sea EaglesManly Sea Eag | 24 - 6 | St. George Illawara DragoSt. George Il |
| 09 May 10 | r09        | Newcastle Knights Newcastle Kni | 36 - 38 | Gold Coast TitansGold Coast Ti |
| 09 May 10 | r09        | Melbourne StormMelbourne Sto | 14 - 36 | Brisbane BroncosBrisbane Bron |
| 10 May 10 | r09        | Sydney RoostersSydney Rooste | 14 - 32 | North Queensland Cowboys North Queensl |
| |
| 14 May 10 | r10        | Brisbane BroncosBrisbane Bron | 28 - 6 | Gold Coast TitansGold Coast Ti |
| 14 May 10 | r10        | Canterbury Bankstown BullCanterbury Ba | 6 - 19 | St. George Illawara DragoSt. George Il |
| 15 May 10 | r10        | New Zealand WarriorsNew Zealand W | 24 - 12 | North Queensland Cowboys North Queensl |
| 15 May 10 | r10        | Canberra RaidersCanberra Raid | 6 - 17 | Melbourne StormMelbourne Sto |
| 15 May 10 | r10        | Sydney RoostersSydney Rooste | 18 - 34 | Newcastle Knights Newcastle Kni |
| 16 May 10 | r10        | Wests TigersWests Tigers | 10 - 50 | South Sydney RabbitohsSouth Sydney |
| 16 May 10 | r10        | Cronulla SharksCronulla Shar | 14 - 34 | Penrith PanthersPenrith Panth |
| 17 May 10 | r10        | Manly Sea EaglesManly Sea Eag | 12 - 19 | Parramatta EelsParramatta Ee |
| |
| 21 May 10 | r11        | Newcastle Knights Newcastle Kni | 6 - 23 | Wests TigersWests Tigers |
| 22 May 10 | r11        | Parramatta EelsParramatta Ee | 18 - 22 | Cronulla SharksCronulla Shar |
| 23 May 10 | r11        | New Zealand WarriorsNew Zealand W | 26 - 24 | South Sydney RabbitohsSouth Sydney |
| 23 May 10 | r11        | St. George Illawara DragoSt. George Il | 14 - 22 | Canberra RaidersCanberra Raid |
| 24 May 10 | r11        | Penrith PanthersPenrith Panth | 31 - 16 | Canterbury Bankstown BullCanterbury Ba |
| |
| 28 May 10 | r12        | St. George Illawara DragoSt. George Il | 30 - 0 | Parramatta EelsParramatta Ee |
| 28 May 10 | r12        | Wests TigersWests Tigers | 50 - 6 | New Zealand WarriorsNew Zealand W |
| 29 May 10 | r12        | Cronulla SharksCronulla Shar | 4 - 20 | Brisbane BroncosBrisbane Bron |
| 29 May 10 | r12        | North Queensland Cowboys North Queensl | 20 - 24 | Manly Sea EaglesManly Sea Eag |
| 30 May 10 | r12        | Melbourne StormMelbourne Sto | 23 - 12 | Canterbury Bankstown BullCanterbury Ba |
| 30 May 10 | r12        | South Sydney RabbitohsSouth Sydney | 42 - 22 | Penrith PanthersPenrith Panth |
| 31 May 10 | r12        | Gold Coast TitansGold Coast Ti | 16 - 30 | Sydney RoostersSydney Rooste |
| |
| 04 Jun 10 | r13        | Canterbury Bankstown BullCanterbury Ba | 12 - 19 | Wests TigersWests Tigers |
| 04 Jun 10 | r13        | Parramatta EelsParramatta Ee | 24 - 10 | Melbourne StormMelbourne Sto |
| 05 Jun 10 | r13        | Penrith PanthersPenrith Panth | 28 - 10 | Newcastle Knights Newcastle Kni |
| 05 Jun 10 | r13        | Sydney RoostersSydney Rooste | 18 - 42 | Cronulla SharksCronulla Shar |
| 06 Jun 10 | r13        | New Zealand WarriorsNew Zealand W | 20 - 22 | St. George Illawara DragoSt. George Il |
| 06 Jun 10 | r13        | Canberra RaidersCanberra Raid | 28 - 24 | Gold Coast TitansGold Coast Ti |
| 06 Jun 10 | r13        | Manly Sea EaglesManly Sea Eag | 6 - 22 | Brisbane BroncosBrisbane Bron |
| 07 Jun 10 | r13        | South Sydney RabbitohsSouth Sydney | 32 - 4 | North Queensland Cowboys North Queensl |
| |
| 11 Jun 10 | r14        | Gold Coast TitansGold Coast Ti | 28 - 14 | Manly Sea EaglesManly Sea Eag |
| 12 Jun 10 | r14        | North Queensland Cowboys North Queensl | 16 - 8 | Canberra RaidersCanberra Raid |
| 13 Jun 10 | r14        | Newcastle Knights Newcastle Kni | 24 - 32 | New Zealand WarriorsNew Zealand W |
| 13 Jun 10 | r14        | Brisbane BroncosBrisbane Bron | 50 - 22 | South Sydney RabbitohsSouth Sydney |