| 24 Jul 21 | r01   | FC HeidenheimFC Heidenheim | 0 - 0 | PaderbornPaderborn |
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| 31 Jul 21 | r02 | IngolstadtIngolstadt | 1 - 2 | FC HeidenheimFC Heidenheim |
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| 15 Aug 21 | r03  | FC HeidenheimFC Heidenheim | 1 - 1 | Hansa RostockHansa Rostock |
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| 20 Aug 21 | r04  | HannoverHannover | 1 - 0 | FC HeidenheimFC Heidenheim |
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| 28 Aug 21 | r05 | FC HeidenheimFC Heidenheim | 0 - 0 | HamburgHamburg |
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| 12 Sep 21 | r06 | FC HeidenheimFC Heidenheim | 2 - 1 | Dynamo DresdenDynamo Dresde |
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| 18 Sep 21 | r07 | SandhausenSandhausen | 1 - 3 | FC HeidenheimFC Heidenheim |
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| 24 Sep 21 | r08 | FC HeidenheimFC Heidenheim | 2 - 1 | DarmstadtDarmstadt |
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| 01 Oct 21 | r09 | Werder BremenWerder Bremen | 3 - 0 | FC HeidenheimFC Heidenheim |
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| 16 Oct 21 | r10 | FC HeidenheimFC Heidenheim | 2 - 4 | St PauliSt Pauli |
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| 23 Oct 21 | r11 | NurnbergNurnberg | 4 - 0 | FC HeidenheimFC Heidenheim |
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| 29 Oct 21 | r12 | FC HeidenheimFC Heidenheim | 1 - 0 | Schalke 04Schalke 04 |
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| 07 Nov 21 | r13 | AueAue | 2 - 0 | FC HeidenheimFC Heidenheim |
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| 21 Nov 21 | r14 | FC HeidenheimFC Heidenheim | 2 - 1 | Holstein KielHolstein Kiel |
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| 26 Nov 21 | r15 | Fortuna DüsseldorfFortuna Düsse | 0 - 1 | FC HeidenheimFC Heidenheim |
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| 05 Dec 21 | r16 | FC HeidenheimFC Heidenheim | 3 - 0 | Jahn RegensburgJahn Regensbu |
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| 12 Dec 21 | r17 | KarlsruheKarlsruhe | 3 - 2 | FC HeidenheimFC Heidenheim |
| |
| 18 Dec 21 | r18 | PaderbornPaderborn | 1 - 2 | FC HeidenheimFC Heidenheim |
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| 16 Jan 22 | r19 | FC HeidenheimFC Heidenheim | 2 - 1 | IngolstadtIngolstadt |
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| 22 Jan 22 | r20 | Hansa RostockHansa Rostock | 0 - 0 | FC HeidenheimFC Heidenheim |
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| 04 Feb 22 | r21 | FC HeidenheimFC Heidenheim | 3 - 1 | HannoverHannover |
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| 12 Feb 22 | r22 | HamburgHamburg | 2 - 0 | FC HeidenheimFC Heidenheim |
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| 18 Feb 22 | r23 | Dynamo DresdenDynamo Dresde | 1 - 1 | FC HeidenheimFC Heidenheim |
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| 27 Feb 22 | r24 | FC HeidenheimFC Heidenheim | 1 - 1 | SandhausenSandhausen |
| |
| 04 Mar 22 | r25 | DarmstadtDarmstadt | 3 - 2 | FC HeidenheimFC Heidenheim |
| |
| 12 Mar 22 | r26  | FC HeidenheimFC Heidenheim | 2 - 1 | Werder BremenWerder Bremen |
| |
| 18 Mar 22 | r27 | St PauliSt Pauli | 1 - 0 | FC HeidenheimFC Heidenheim |
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| 03 Apr 22 | r28 | FC HeidenheimFC Heidenheim | 3 - 1 | NurnbergNurnberg |
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| 09 Apr 22 | r29 | Schalke 04Schalke 04 | 3 - 0 | FC HeidenheimFC Heidenheim |
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| 17 Apr 22 | r30 | FC HeidenheimFC Heidenheim | 0 - 2 | AueAue |
| |
| 23 Apr 22 | r31 | Holstein KielHolstein Kiel | 1 - 1 | FC HeidenheimFC Heidenheim |
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| 29 Apr 22 | r32 | FC HeidenheimFC Heidenheim | 1 - 3 | Fortuna DüsseldorfFortuna Düsse |
| |
| 07 May 22 | r33 | Jahn RegensburgJahn Regensbu | 0 - 2 | FC HeidenheimFC Heidenheim |
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| 15 May 22 | r34 | FC HeidenheimFC Heidenheim | 2 - 0 | KarlsruheKarlsruhe |
Team 2021-2022 Schedules
Arminia Bielefeld
Bochum
Darmstadt
Dynamo Dresden
Eintracht Braunschweig
Greuther Fürth
Hannover 96
Heidenheim
Hertha
Holstein Kiel
Kaiserslautern
Karlsruhe
Magdeburg
Nürnberg
St Pauli
Wolfsburg
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