| 30 Oct 88 | r09        | Buffalo BillsBuffalo Bills | 28 - 0 | Green Bay PackersGreen Bay Pac |
| 30 Oct 88 | r09        | Cleveland BrownsCleveland Bro | 23 - 16 | Cincinnati BengalsCincinnati Be |
| 30 Oct 88 | r09        | Dallas CowboysDallas Cowboy | 10 - 16 | Arizona CardinalsArizona Cardi |
| 30 Oct 88 | r09        | New England PatriotsNew England P | 30 - 7 | Chicago BearsChicago Bears |
| 30 Oct 88 | r09        | New Orleans SaintsNew Orleans S | 10 - 12 | Los Angeles RamsLos Angeles R |
| 30 Oct 88 | r09        | New York JetsNew York Jets | 24 - 20 | Pittsburgh SteelersPittsburgh St |
| 30 Oct 88 | r09        | Philadelphia EaglesPhiladelphia | 24 - 27 | Atlanta FalconsAtlanta Falco |
| 30 Oct 88 | r09        | Tampa Bay BuccaneersTampa Bay Buc | 14 - 17 | Miami DolphinsMiami Dolphin |
| 30 Oct 88 | r09        | Detroit LionsDetroit Lions | 10 - 13 | New York GiantsNew York Gian |
| 30 Oct 88 | r09        | Las Vegas RaidersLas Vegas Rai | 17 - 10 | Kansas City ChiefsKansas City C |
| 30 Oct 88 | r09        | San Francisco 49ersSan Francisco | 24 - 21 | Minnesota VikingsMinnesota Vik |
| 30 Oct 88 | r09        | Seattle SeahawksSeattle Seaha | 17 - 14 | Los Angeles ChargersLos Angeles C |
| 31 Oct 88 | r09        | Tennessee TitansTennessee Tit | 41 - 17 | Washington CommandersWashington Co |
| 01 Nov 88 | r09        | Indianapolis ColtsIndianapolis | 55 - 23 | Denver BroncosDenver Bronco |