| 04 Sep 88 | r01        | Chicago BearsChicago Bears | 34 - 7 | Miami DolphinsMiami Dolphin |
| 04 Sep 88 | r01        | Green Bay PackersGreen Bay Pac | 7 - 34 | Los Angeles RamsLos Angeles R |
| 04 Sep 88 | r01        | New Orleans SaintsNew Orleans S | 33 - 34 | San Francisco 49ersSan Francisco |
| 04 Sep 88 | r01        | Buffalo BillsBuffalo Bills | 13 - 10 | Minnesota VikingsMinnesota Vik |
| 04 Sep 88 | r01        | Cincinnati BengalsCincinnati Be | 21 - 14 | Arizona CardinalsArizona Cardi |
| 04 Sep 88 | r01        | Detroit LionsDetroit Lions | 31 - 17 | Atlanta FalconsAtlanta Falco |
| 04 Sep 88 | r01        | Pittsburgh SteelersPittsburgh St | 24 - 21 | Dallas CowboysDallas Cowboy |
| 04 Sep 88 | r01        | Tampa Bay BuccaneersTampa Bay Buc | 14 - 41 | Philadelphia EaglesPhiladelphia |
| 04 Sep 88 | r01        | Denver BroncosDenver Bronco | 14 - 21 | Seattle SeahawksSeattle Seaha |
| 04 Sep 88 | r01        | Indianapolis ColtsIndianapolis | 14 - 17 | Tennessee TitansTennessee Tit |
| 04 Sep 88 | r01        | Kansas City ChiefsKansas City C | 3 - 6 | Cleveland BrownsCleveland Bro |
| 04 Sep 88 | r01        | Las Vegas RaidersLas Vegas Rai | 24 - 13 | Los Angeles ChargersLos Angeles C |
| 04 Sep 88 | r01        | New England PatriotsNew England P | 28 - 3 | New York JetsNew York Jets |
| 06 Sep 88 | r01        | New York GiantsNew York Gian | 27 - 20 | Washington CommandersWashington Co |
| |
| 11 Sep 88 | r02        | Green Bay PackersGreen Bay Pac | 10 - 13 | Tampa Bay BuccaneersTampa Bay Buc |
| 11 Sep 88 | r02        | Indianapolis ColtsIndianapolis | 13 - 17 | Chicago BearsChicago Bears |
| 11 Sep 88 | r02        | Atlanta FalconsAtlanta Falco | 21 - 29 | New Orleans SaintsNew Orleans S |
| 11 Sep 88 | r02        | Buffalo BillsBuffalo Bills | 9 - 6 | Miami DolphinsMiami Dolphin |
| 11 Sep 88 | r02        | New York GiantsNew York Gian | 17 - 20 | San Francisco 49ersSan Francisco |
| 11 Sep 88 | r02        | Washington CommandersWashington Co | 30 - 29 | Pittsburgh SteelersPittsburgh St |
| 11 Sep 88 | r02        | Denver BroncosDenver Bronco | 34 - 3 | Los Angeles ChargersLos Angeles C |
| 11 Sep 88 | r02        | Minnesota VikingsMinnesota Vik | 36 - 6 | New England PatriotsNew England P |
| 11 Sep 88 | r02        | Tennessee TitansTennessee Tit | 38 - 35 | Las Vegas RaidersLas Vegas Rai |
| 11 Sep 88 | r02        | Cleveland BrownsCleveland Bro | 3 - 23 | New York JetsNew York Jets |
| 11 Sep 88 | r02        | Los Angeles RamsLos Angeles R | 17 - 10 | Detroit LionsDetroit Lions |
| 11 Sep 88 | r02        | Philadelphia EaglesPhiladelphia | 24 - 28 | Cincinnati BengalsCincinnati Be |
| 11 Sep 88 | r02        | Seattle SeahawksSeattle Seaha | 31 - 10 | Kansas City ChiefsKansas City C |
| 13 Sep 88 | r02        | Arizona CardinalsArizona Cardi | 14 - 17 | Dallas CowboysDallas Cowboy |
| |
| 18 Sep 88 | r03        | Chicago BearsChicago Bears | 7 - 31 | Minnesota VikingsMinnesota Vik |
| 18 Sep 88 | r03        | Kansas City ChiefsKansas City C | 20 - 13 | Denver BroncosDenver Bronco |
| 18 Sep 88 | r03        | Detroit LionsDetroit Lions | 14 - 22 | New Orleans SaintsNew Orleans S |
| 18 Sep 88 | r03        | Miami DolphinsMiami Dolphin | 24 - 17 | Green Bay PackersGreen Bay Pac |
| 18 Sep 88 | r03        | New England PatriotsNew England P | 14 - 16 | Buffalo BillsBuffalo Bills |
| 18 Sep 88 | r03        | New York JetsNew York Jets | 45 - 3 | Tennessee TitansTennessee Tit |
| 18 Sep 88 | r03        | Pittsburgh SteelersPittsburgh St | 12 - 17 | Cincinnati BengalsCincinnati Be |
| 18 Sep 88 | r03        | Tampa Bay BuccaneersTampa Bay Buc | 24 - 30 | Arizona CardinalsArizona Cardi |
| 18 Sep 88 | r03        | Washington CommandersWashington Co | 17 - 10 | Philadelphia EaglesPhiladelphia |
| 18 Sep 88 | r03        | Las Vegas RaidersLas Vegas Rai | 17 - 22 | Los Angeles RamsLos Angeles R |
| 18 Sep 88 | r03        | Los Angeles ChargersLos Angeles C | 17 - 6 | Seattle SeahawksSeattle Seaha |
| 18 Sep 88 | r03        | San Francisco 49ersSan Francisco | 17 - 34 | Atlanta FalconsAtlanta Falco |
| 18 Sep 88 | r03        | Dallas CowboysDallas Cowboy | 10 - 12 | New York GiantsNew York Gian |
| 20 Sep 88 | r03        | Cleveland BrownsCleveland Bro | 23 - 17 | Indianapolis ColtsIndianapolis |
| |
| 25 Sep 88 | r04        | Dallas CowboysDallas Cowboy | 26 - 20 | Atlanta FalconsAtlanta Falco |
| 25 Sep 88 | r04        | Green Bay PackersGreen Bay Pac | 6 - 24 | Chicago BearsChicago Bears |
| 25 Sep 88 | r04        | Indianapolis ColtsIndianapolis | 15 - 13 | Miami DolphinsMiami Dolphin |
| 25 Sep 88 | r04        | Minnesota VikingsMinnesota Vik | 23 - 21 | Philadelphia EaglesPhiladelphia |
| 25 Sep 88 | r04        | New Orleans SaintsNew Orleans S | 13 - 9 | Tampa Bay BuccaneersTampa Bay Buc |
| 25 Sep 88 | r04        | Tennessee TitansTennessee Tit | 31 - 6 | New England PatriotsNew England P |
| 25 Sep 88 | r04        | Buffalo BillsBuffalo Bills | 36 - 28 | Pittsburgh SteelersPittsburgh St |
| 25 Sep 88 | r04        | Cincinnati BengalsCincinnati Be | 24 - 17 | Cleveland BrownsCleveland Bro |
| 25 Sep 88 | r04        | Detroit LionsDetroit Lions | 10 - 17 | New York JetsNew York Jets |
| 25 Sep 88 | r04        | Kansas City ChiefsKansas City C | 23 - 24 | Los Angeles ChargersLos Angeles C |
| 25 Sep 88 | r04        | Arizona CardinalsArizona Cardi | 30 - 21 | Washington CommandersWashington Co |
| 25 Sep 88 | r04        | New York GiantsNew York Gian | 31 - 45 | Los Angeles RamsLos Angeles R |
| 25 Sep 88 | r04        | Seattle SeahawksSeattle Seaha | 7 - 38 | San Francisco 49ersSan Francisco |
| 27 Sep 88 | r04        | Denver BroncosDenver Bronco | 27 - 30 | Las Vegas RaidersLas Vegas Rai |
| |
| 02 Oct 88 | r05        | Chicago BearsChicago Bears | 24 - 3 | Buffalo BillsBuffalo Bills |
| 02 Oct 88 | r05        | Atlanta FalconsAtlanta Falco | 20 - 31 | Seattle SeahawksSeattle Seaha |
| 02 Oct 88 | r05        | New England PatriotsNew England P | 21 - 17 | Indianapolis ColtsIndianapolis |
| 02 Oct 88 | r05        | Philadelphia EaglesPhiladelphia | 32 - 23 | Tennessee TitansTennessee Tit |
| 02 Oct 88 | r05        | Pittsburgh SteelersPittsburgh St | 9 - 23 | Cleveland BrownsCleveland Bro |
| 02 Oct 88 | r05        | Tampa Bay BuccaneersTampa Bay Buc | 27 - 24 | Green Bay PackersGreen Bay Pac |
| 02 Oct 88 | r05        | Washington CommandersWashington Co | 23 - 24 | New York GiantsNew York Gian |
| 02 Oct 88 | r05        | Las Vegas RaidersLas Vegas Rai | 21 - 45 | Cincinnati BengalsCincinnati Be |
| 02 Oct 88 | r05        | Los Angeles ChargersLos Angeles C | 0 - 12 | Denver BroncosDenver Bronco |
| 02 Oct 88 | r05        | Los Angeles RamsLos Angeles R | 27 - 41 | Arizona CardinalsArizona Cardi |
| 02 Oct 88 | r05        | Miami DolphinsMiami Dolphin | 24 - 7 | Minnesota VikingsMinnesota Vik |
| 02 Oct 88 | r05        | New York JetsNew York Jets | 17 - 17 | Kansas City ChiefsKansas City C |
| 02 Oct 88 | r05        | San Francisco 49ersSan Francisco | 20 - 13 | Detroit LionsDetroit Lions |
| 04 Oct 88 | r05        | New Orleans SaintsNew Orleans S | 20 - 17 | Dallas CowboysDallas Cowboy |
| |
| 09 Oct 88 | r06        | Dallas CowboysDallas Cowboy | 17 - 35 | Washington CommandersWashington Co |
| 09 Oct 88 | r06        | Green Bay PackersGreen Bay Pac | 45 - 3 | New England PatriotsNew England P |
| 09 Oct 88 | r06        | Minnesota VikingsMinnesota Vik | 14 - 13 | Tampa Bay BuccaneersTampa Bay Buc |
| 09 Oct 88 | r06        | Tennessee TitansTennessee Tit | 7 - 6 | Kansas City ChiefsKansas City C |
| 09 Oct 88 | r06        | Atlanta FalconsAtlanta Falco | 0 - 33 | Los Angeles RamsLos Angeles R |
| 09 Oct 88 | r06        | Buffalo BillsBuffalo Bills | 34 - 23 | Indianapolis ColtsIndianapolis |
| 09 Oct 88 | r06        | Cincinnati BengalsCincinnati Be | 36 - 19 | New York JetsNew York Jets |
| 09 Oct 88 | r06        | Cleveland BrownsCleveland Bro | 10 - 16 | Seattle SeahawksSeattle Seaha |
| 09 Oct 88 | r06        | Detroit LionsDetroit Lions | 7 - 24 | Chicago BearsChicago Bears |
| 09 Oct 88 | r06        | Arizona CardinalsArizona Cardi | 31 - 14 | Pittsburgh SteelersPittsburgh St |
| 09 Oct 88 | r06        | Las Vegas RaidersLas Vegas Rai | 14 - 24 | Miami DolphinsMiami Dolphin |
| 09 Oct 88 | r06        | Los Angeles ChargersLos Angeles C | 17 - 23 | New Orleans SaintsNew Orleans S |
| 09 Oct 88 | r06        | San Francisco 49ersSan Francisco | 13 - 16 | Denver BroncosDenver Bronco |
| 11 Oct 88 | r06        | Philadelphia EaglesPhiladelphia | 24 - 13 | New York GiantsNew York Gian |
| |
| 16 Oct 88 | r07        | Chicago BearsChicago Bears | 17 - 7 | Dallas CowboysDallas Cowboy |
| 16 Oct 88 | r07        | Indianapolis ColtsIndianapolis | 35 - 31 | Tampa Bay BuccaneersTampa Bay Buc |
| 16 Oct 88 | r07        | Kansas City ChiefsKansas City C | 17 - 27 | Las Vegas RaidersLas Vegas Rai |
| 16 Oct 88 | r07        | Minnesota VikingsMinnesota Vik | 14 - 34 | Green Bay PackersGreen Bay Pac |
| 16 Oct 88 | r07        | Cleveland BrownsCleveland Bro | 19 - 3 | Philadelphia EaglesPhiladelphia |
| 16 Oct 88 | r07        | New England PatriotsNew England P | 27 - 21 | Cincinnati BengalsCincinnati Be |
| 16 Oct 88 | r07        | New York GiantsNew York Gian | 30 - 10 | Detroit LionsDetroit Lions |
| 16 Oct 88 | r07        | Pittsburgh SteelersPittsburgh St | 14 - 34 | Tennessee TitansTennessee Tit |
| 16 Oct 88 | r07        | Washington CommandersWashington Co | 33 - 17 | Arizona CardinalsArizona Cardi |
| 16 Oct 88 | r07        | Denver BroncosDenver Bronco | 30 - 14 | Atlanta FalconsAtlanta Falco |
| 16 Oct 88 | r07        | Los Angeles RamsLos Angeles R | 21 - 24 | San Francisco 49ersSan Francisco |
| 16 Oct 88 | r07        | Miami DolphinsMiami Dolphin | 31 - 28 | Los Angeles ChargersLos Angeles C |
| 16 Oct 88 | r07        | Seattle SeahawksSeattle Seaha | 19 - 20 | New Orleans SaintsNew Orleans S |
| 18 Oct 88 | r07        | New York JetsNew York Jets | 14 - 37 | Buffalo BillsBuffalo Bills |
| |
| 23 Oct 88 | r08        | Kansas City ChiefsKansas City C | 6 - 7 | Detroit LionsDetroit Lions |
| 23 Oct 88 | r08        | New Orleans SaintsNew Orleans S | 20 - 6 | Las Vegas RaidersLas Vegas Rai |