| 07 Sep 80 | r01        | Arizona CardinalsArizona Cardi | 35 - 41 | New York GiantsNew York Gian |
| 07 Sep 80 | r01        | Green Bay PackersGreen Bay Pac | 12 - 6 | Chicago BearsChicago Bears |
| 07 Sep 80 | r01        | Minnesota VikingsMinnesota Vik | 24 - 23 | Atlanta FalconsAtlanta Falco |
| 07 Sep 80 | r01        | New Orleans SaintsNew Orleans S | 23 - 26 | San Francisco 49ersSan Francisco |
| 07 Sep 80 | r01        | Buffalo BillsBuffalo Bills | 17 - 7 | Miami DolphinsMiami Dolphin |
| 07 Sep 80 | r01        | Cincinnati BengalsCincinnati Be | 12 - 17 | Tampa Bay BuccaneersTampa Bay Buc |
| 07 Sep 80 | r01        | New England PatriotsNew England P | 34 - 17 | Cleveland BrownsCleveland Bro |
| 07 Sep 80 | r01        | Pittsburgh SteelersPittsburgh St | 31 - 17 | Tennessee TitansTennessee Tit |
| 07 Sep 80 | r01        | Kansas City ChiefsKansas City C | 14 - 27 | Las Vegas RaidersLas Vegas Rai |
| 07 Sep 80 | r01        | Los Angeles RamsLos Angeles R | 20 - 41 | Detroit LionsDetroit Lions |
| 07 Sep 80 | r01        | New York JetsNew York Jets | 14 - 17 | Indianapolis ColtsIndianapolis |
| 07 Sep 80 | r01        | Philadelphia EaglesPhiladelphia | 27 - 6 | Denver BroncosDenver Bronco |
| 07 Sep 80 | r01        | Seattle SeahawksSeattle Seaha | 13 - 34 | Los Angeles ChargersLos Angeles C |
| 09 Sep 80 | r01        | Washington CommandersWashington Co | 3 - 17 | Dallas CowboysDallas Cowboy |
| |
| 12 Sep 80 | r02        | Tampa Bay BuccaneersTampa Bay Buc | 10 - 9 | Los Angeles RamsLos Angeles R |
| 14 Sep 80 | r02        | Minnesota VikingsMinnesota Vik | 7 - 42 | Philadelphia EaglesPhiladelphia |
| 14 Sep 80 | r02        | Buffalo BillsBuffalo Bills | 20 - 10 | New York JetsNew York Jets |
| 14 Sep 80 | r02        | New England PatriotsNew England P | 21 - 37 | Atlanta FalconsAtlanta Falco |
| 14 Sep 80 | r02        | Chicago BearsChicago Bears | 22 - 3 | New Orleans SaintsNew Orleans S |
| 14 Sep 80 | r02        | Green Bay PackersGreen Bay Pac | 7 - 29 | Detroit LionsDetroit Lions |
| 14 Sep 80 | r02        | Indianapolis ColtsIndianapolis | 17 - 20 | Pittsburgh SteelersPittsburgh St |
| 14 Sep 80 | r02        | Kansas City ChiefsKansas City C | 16 - 17 | Seattle SeahawksSeattle Seaha |
| 14 Sep 80 | r02        | Denver BroncosDenver Bronco | 41 - 20 | Dallas CowboysDallas Cowboy |
| 14 Sep 80 | r02        | Los Angeles ChargersLos Angeles C | 30 - 24 | Las Vegas RaidersLas Vegas Rai |
| 14 Sep 80 | r02        | Miami DolphinsMiami Dolphin | 17 - 16 | Cincinnati BengalsCincinnati Be |
| 14 Sep 80 | r02        | New York GiantsNew York Gian | 21 - 23 | Washington CommandersWashington Co |
| 14 Sep 80 | r02        | San Francisco 49ersSan Francisco | 24 - 21 | Arizona CardinalsArizona Cardi |
| 16 Sep 80 | r02        | Cleveland BrownsCleveland Bro | 7 - 16 | Tennessee TitansTennessee Tit |
| |
| 21 Sep 80 | r03        | Chicago BearsChicago Bears | 14 - 34 | Minnesota VikingsMinnesota Vik |
| 21 Sep 80 | r03        | Atlanta FalconsAtlanta Falco | 17 - 20 | Miami DolphinsMiami Dolphin |
| 21 Sep 80 | r03        | Cincinnati BengalsCincinnati Be | 30 - 28 | Pittsburgh SteelersPittsburgh St |
| 21 Sep 80 | r03        | Cleveland BrownsCleveland Bro | 20 - 13 | Kansas City ChiefsKansas City C |
| 21 Sep 80 | r03        | Detroit LionsDetroit Lions | 20 - 7 | Arizona CardinalsArizona Cardi |
| 21 Sep 80 | r03        | New York JetsNew York Jets | 27 - 37 | San Francisco 49ersSan Francisco |
| 21 Sep 80 | r03        | New Orleans SaintsNew Orleans S | 26 - 35 | Buffalo BillsBuffalo Bills |
| 21 Sep 80 | r03        | Tennessee TitansTennessee Tit | 21 - 16 | Indianapolis ColtsIndianapolis |
| 21 Sep 80 | r03        | Dallas CowboysDallas Cowboy | 28 - 17 | Tampa Bay BuccaneersTampa Bay Buc |
| 21 Sep 80 | r03        | Denver BroncosDenver Bronco | 13 - 30 | Los Angeles ChargersLos Angeles C |
| 21 Sep 80 | r03        | Las Vegas RaidersLas Vegas Rai | 24 - 21 | Washington CommandersWashington Co |
| 21 Sep 80 | r03        | Los Angeles RamsLos Angeles R | 51 - 21 | Green Bay PackersGreen Bay Pac |
| 21 Sep 80 | r03        | Seattle SeahawksSeattle Seaha | 31 - 37 | New England PatriotsNew England P |
| 23 Sep 80 | r03        | Philadelphia EaglesPhiladelphia | 35 - 3 | New York GiantsNew York Gian |
| |
| 28 Sep 80 | r04        | Buffalo BillsBuffalo Bills | 24 - 7 | Las Vegas RaidersLas Vegas Rai |
| 28 Sep 80 | r04        | Cincinnati BengalsCincinnati Be | 10 - 13 | Tennessee TitansTennessee Tit |
| 28 Sep 80 | r04        | Detroit LionsDetroit Lions | 27 - 7 | Minnesota VikingsMinnesota Vik |
| 28 Sep 80 | r04        | Miami DolphinsMiami Dolphin | 21 - 16 | New Orleans SaintsNew Orleans S |
| 28 Sep 80 | r04        | New York GiantsNew York Gian | 7 - 28 | Los Angeles RamsLos Angeles R |
| 28 Sep 80 | r04        | Pittsburgh SteelersPittsburgh St | 38 - 3 | Chicago BearsChicago Bears |
| 28 Sep 80 | r04        | Tampa Bay BuccaneersTampa Bay Buc | 27 - 34 | Cleveland BrownsCleveland Bro |
| 28 Sep 80 | r04        | Arizona CardinalsArizona Cardi | 24 - 14 | Philadelphia EaglesPhiladelphia |
| 28 Sep 80 | r04        | Green Bay PackersGreen Bay Pac | 7 - 28 | Dallas CowboysDallas Cowboy |
| 28 Sep 80 | r04        | Kansas City ChiefsKansas City C | 7 - 24 | Los Angeles ChargersLos Angeles C |
| 28 Sep 80 | r04        | Indianapolis ColtsIndianapolis | 35 - 21 | New York JetsNew York Jets |
| 28 Sep 80 | r04        | San Francisco 49ersSan Francisco | 17 - 20 | Atlanta FalconsAtlanta Falco |
| 28 Sep 80 | r04        | Washington CommandersWashington Co | 0 - 14 | Seattle SeahawksSeattle Seaha |
| 30 Sep 80 | r04        | New England PatriotsNew England P | 23 - 14 | Denver BroncosDenver Bronco |
| |
| 05 Oct 80 | r05        | Minnesota VikingsMinnesota Vik | 17 - 23 | Pittsburgh SteelersPittsburgh St |
| 05 Oct 80 | r05        | New Orleans SaintsNew Orleans S | 7 - 40 | Arizona CardinalsArizona Cardi |
| 05 Oct 80 | r05        | Tennessee TitansTennessee Tit | 7 - 26 | Seattle SeahawksSeattle Seaha |
| 05 Oct 80 | r05        | Atlanta FalconsAtlanta Falco | 43 - 28 | Detroit LionsDetroit Lions |
| 05 Oct 80 | r05        | Cleveland BrownsCleveland Bro | 16 - 19 | Denver BroncosDenver Bronco |
| 05 Oct 80 | r05        | Miami DolphinsMiami Dolphin | 17 - 30 | Indianapolis ColtsIndianapolis |
| 05 Oct 80 | r05        | New York JetsNew York Jets | 11 - 21 | New England PatriotsNew England P |
| 05 Oct 80 | r05        | Philadelphia EaglesPhiladelphia | 24 - 14 | Washington CommandersWashington Co |
| 05 Oct 80 | r05        | Green Bay PackersGreen Bay Pac | 14 - 9 | Cincinnati BengalsCincinnati Be |
| 05 Oct 80 | r05        | Dallas CowboysDallas Cowboy | 24 - 3 | New York GiantsNew York Gian |
| 05 Oct 80 | r05        | Las Vegas RaidersLas Vegas Rai | 17 - 31 | Kansas City ChiefsKansas City C |
| 05 Oct 80 | r05        | Los Angeles ChargersLos Angeles C | 24 - 26 | Buffalo BillsBuffalo Bills |
| 05 Oct 80 | r05        | Los Angeles RamsLos Angeles R | 48 - 26 | San Francisco 49ersSan Francisco |
| 07 Oct 80 | r05        | Chicago BearsChicago Bears | 23 - 0 | Tampa Bay BuccaneersTampa Bay Buc |
| |
| 12 Oct 80 | r06        | Buffalo BillsBuffalo Bills | 12 - 17 | Indianapolis ColtsIndianapolis |
| 12 Oct 80 | r06        | New England PatriotsNew England P | 34 - 0 | Miami DolphinsMiami Dolphin |
| 12 Oct 80 | r06        | New York GiantsNew York Gian | 16 - 31 | Philadelphia EaglesPhiladelphia |
| 12 Oct 80 | r06        | Pittsburgh SteelersPittsburgh St | 16 - 17 | Cincinnati BengalsCincinnati Be |
| 12 Oct 80 | r06        | Tampa Bay BuccaneersTampa Bay Buc | 14 - 14 | Green Bay PackersGreen Bay Pac |
| 12 Oct 80 | r06        | Arizona CardinalsArizona Cardi | 13 - 21 | Los Angeles RamsLos Angeles R |
| 12 Oct 80 | r06        | Dallas CowboysDallas Cowboy | 59 - 14 | San Francisco 49ersSan Francisco |
| 12 Oct 80 | r06        | Minnesota VikingsMinnesota Vik | 13 - 7 | Chicago BearsChicago Bears |
| 12 Oct 80 | r06        | Kansas City ChiefsKansas City C | 21 - 20 | Tennessee TitansTennessee Tit |
| 12 Oct 80 | r06        | Atlanta FalconsAtlanta Falco | 7 - 14 | New York JetsNew York Jets |
| 12 Oct 80 | r06        | Detroit LionsDetroit Lions | 24 - 13 | New Orleans SaintsNew Orleans S |
| 12 Oct 80 | r06        | Las Vegas RaidersLas Vegas Rai | 38 - 24 | Los Angeles ChargersLos Angeles C |
| 12 Oct 80 | r06        | Seattle SeahawksSeattle Seaha | 3 - 27 | Cleveland BrownsCleveland Bro |
| 14 Oct 80 | r06        | Denver BroncosDenver Bronco | 20 - 17 | Washington CommandersWashington Co |
| |
| 19 Oct 80 | r07        | Cincinnati BengalsCincinnati Be | 14 - 0 | Minnesota VikingsMinnesota Vik |
| 19 Oct 80 | r07        | Cleveland BrownsCleveland Bro | 26 - 21 | Green Bay PackersGreen Bay Pac |
| 19 Oct 80 | r07        | Miami DolphinsMiami Dolphin | 17 - 14 | Buffalo BillsBuffalo Bills |
| 19 Oct 80 | r07        | New York JetsNew York Jets | 17 - 27 | Seattle SeahawksSeattle Seaha |
| 19 Oct 80 | r07        | Philadelphia EaglesPhiladelphia | 17 - 10 | Dallas CowboysDallas Cowboy |
| 19 Oct 80 | r07        | Washington CommandersWashington Co | 23 - 0 | Arizona CardinalsArizona Cardi |
| 19 Oct 80 | r07        | Chicago BearsChicago Bears | 24 - 7 | Detroit LionsDetroit Lions |
| 19 Oct 80 | r07        | Denver BroncosDenver Bronco | 17 - 23 | Kansas City ChiefsKansas City C |
| 19 Oct 80 | r07        | Indianapolis ColtsIndianapolis | 21 - 37 | New England PatriotsNew England P |
| 19 Oct 80 | r07        | New Orleans SaintsNew Orleans S | 14 - 41 | Atlanta FalconsAtlanta Falco |
| 19 Oct 80 | r07        | Tennessee TitansTennessee Tit | 20 - 14 | Tampa Bay BuccaneersTampa Bay Buc |
| 19 Oct 80 | r07        | Los Angeles ChargersLos Angeles C | 44 - 7 | New York GiantsNew York Gian |
| 19 Oct 80 | r07        | San Francisco 49ersSan Francisco | 17 - 31 | Los Angeles RamsLos Angeles R |
| 21 Oct 80 | r07        | Pittsburgh SteelersPittsburgh St | 34 - 45 | Las Vegas RaidersLas Vegas Rai |
| |
| 26 Oct 80 | r08        | Atlanta FalconsAtlanta Falco | 13 - 10 | Los Angeles RamsLos Angeles R |
| 26 Oct 80 | r08        | Buffalo BillsBuffalo Bills | 31 - 13 | New England PatriotsNew England P |