| 12 Sep 20 | r01      | FulhamFulham | 0 - 3 | ArsenalArsenal |
| 12 Sep 20 | r01 | Crystal PalaceCrystal Palac | 1 - 0 | SouthamptonSouthampton |
| 12 Sep 20 | r01 | LiverpoolLiverpool | 4 - 3 | LeedsLeeds |
| 12 Sep 20 | r01 | West HamWest Ham | 0 - 2 | NewcastleNewcastle |
| 13 Sep 20 | r01 | West BromWest Brom | 0 - 3 | LeicesterLeicester |
| 13 Sep 20 | r01 | TottenhamTottenham | 0 - 1 | EvertonEverton |
| 14 Sep 20 | r01 | Sheffield UnitedSheffield Uni | 0 - 2 | WolvesWolves |
| 14 Sep 20 | r01 | BrightonBrighton | 1 - 3 | ChelseaChelsea |
| |
| 19 Sep 20 | r02 | EvertonEverton | 5 - 2 | West BromWest Brom |
| 19 Sep 20 | r02 | LeedsLeeds | 4 - 3 | FulhamFulham |
| 19 Sep 20 | r02 | Manchester UnitedManchester Un | 1 - 3 | Crystal PalaceCrystal Palac |
| 19 Sep 20 | r02 | ArsenalArsenal | 2 - 1 | West HamWest Ham |
| 20 Sep 20 | r02 | SouthamptonSouthampton | 2 - 5 | TottenhamTottenham |
| 20 Sep 20 | r02 | NewcastleNewcastle | 0 - 3 | BrightonBrighton |
| 20 Sep 20 | r02 | ChelseaChelsea | 0 - 2 | LiverpoolLiverpool |
| 20 Sep 20 | r02 | LeicesterLeicester | 4 - 2 | BurnleyBurnley |
| 21 Sep 20 | r02 | Aston VillaAston Villa | 1 - 0 | Sheffield UnitedSheffield Uni |
| 21 Sep 20 | r02 | WolvesWolves | 1 - 3 | Manchester CityManchester Ci |
| |
| 26 Sep 20 | r03 | BrightonBrighton | 2 - 3 | Manchester UnitedManchester Un |
| 26 Sep 20 | r03 | Crystal PalaceCrystal Palac | 1 - 2 | EvertonEverton |
| 26 Sep 20 | r03 | West BromWest Brom | 3 - 3 | ChelseaChelsea |
| 26 Sep 20 | r03 | BurnleyBurnley | 0 - 1 | SouthamptonSouthampton |
| 27 Sep 20 | r03 | Sheffield UnitedSheffield Uni | 0 - 1 | LeedsLeeds |
| 27 Sep 20 | r03 | TottenhamTottenham | 1 - 1 | NewcastleNewcastle |
| 27 Sep 20 | r03 | Manchester CityManchester Ci | 2 - 5 | LeicesterLeicester |
| 27 Sep 20 | r03 | West HamWest Ham | 4 - 0 | WolvesWolves |
| 28 Sep 20 | r03 | FulhamFulham | 0 - 3 | Aston VillaAston Villa |
| 28 Sep 20 | r03 | LiverpoolLiverpool | 3 - 1 | ArsenalArsenal |
| |
| 03 Oct 20 | r04 | ChelseaChelsea | 4 - 0 | Crystal PalaceCrystal Palac |
| 03 Oct 20 | r04 | EvertonEverton | 4 - 2 | BrightonBrighton |
| 03 Oct 20 | r04 | LeedsLeeds | 1 - 1 | Manchester CityManchester Ci |
| 03 Oct 20 | r04 | NewcastleNewcastle | 3 - 1 | BurnleyBurnley |
| 04 Oct 20 | r04 | LeicesterLeicester | 0 - 3 | West HamWest Ham |
| 04 Oct 20 | r04 | SouthamptonSouthampton | 2 - 0 | West BromWest Brom |
| 04 Oct 20 | r04 | ArsenalArsenal | 2 - 1 | Sheffield UnitedSheffield Uni |
| 04 Oct 20 | r04 | WolvesWolves | 1 - 0 | FulhamFulham |
| 04 Oct 20 | r04 | Manchester UnitedManchester Un | 1 - 6 | TottenhamTottenham |
| 04 Oct 20 | r04  | Aston VillaAston Villa | 7 - 2 | LiverpoolLiverpool |
| |
| 17 Oct 20 | r05 | EvertonEverton | 2 - 2 | LiverpoolLiverpool |
| 17 Oct 20 | r05 | ChelseaChelsea | 3 - 3 | SouthamptonSouthampton |
| 17 Oct 20 | r05 | Manchester CityManchester Ci | 1 - 0 | ArsenalArsenal |
| 17 Oct 20 | r05 | NewcastleNewcastle | 1 - 4 | Manchester UnitedManchester Un |
| 18 Oct 20 | r05 | Sheffield UnitedSheffield Uni | 1 - 1 | FulhamFulham |
| 18 Oct 20 | r05 | Crystal PalaceCrystal Palac | 1 - 1 | BrightonBrighton |
| 18 Oct 20 | r05 | TottenhamTottenham | 3 - 3 | West HamWest Ham |
| 18 Oct 20 | r05 | LeicesterLeicester | 0 - 1 | Aston VillaAston Villa |
| 19 Oct 20 | r05 | West BromWest Brom | 0 - 0 | BurnleyBurnley |
| 19 Oct 20 | r05 | LeedsLeeds | 0 - 1 | WolvesWolves |
| |
| 23 Oct 20 | r06 | Aston VillaAston Villa | 0 - 3 | LeedsLeeds |
| 24 Oct 20 | r06 | West HamWest Ham | 1 - 1 | Manchester CityManchester Ci |
| 24 Oct 20 | r06 | FulhamFulham | 1 - 2 | Crystal PalaceCrystal Palac |
| 24 Oct 20 | r06 | Manchester UnitedManchester Un | 0 - 0 | ChelseaChelsea |
| 24 Oct 20 | r06 | LiverpoolLiverpool | 2 - 1 | Sheffield UnitedSheffield Uni |
| 25 Oct 20 | r06 | SouthamptonSouthampton | 2 - 0 | EvertonEverton |
| 25 Oct 20 | r06 | WolvesWolves | 1 - 1 | NewcastleNewcastle |
| 25 Oct 20 | r06 | ArsenalArsenal | 0 - 1 | LeicesterLeicester |
| 26 Oct 20 | r06 | BrightonBrighton | 1 - 1 | West BromWest Brom |
| 26 Oct 20 | r06 | BurnleyBurnley | 0 - 1 | TottenhamTottenham |
| |
| 30 Oct 20 | r07 | WolvesWolves | 2 - 0 | Crystal PalaceCrystal Palac |
| 31 Oct 20 | r07 | Sheffield UnitedSheffield Uni | 0 - 1 | Manchester CityManchester Ci |
| 31 Oct 20 | r07 | BurnleyBurnley | 0 - 3 | ChelseaChelsea |
| 31 Oct 20 | r07 | LiverpoolLiverpool | 2 - 1 | West HamWest Ham |
| 01 Nov 20 | r07 | Aston VillaAston Villa | 3 - 4 | SouthamptonSouthampton |
| 01 Nov 20 | r07 | NewcastleNewcastle | 2 - 1 | EvertonEverton |
| 01 Nov 20 | r07 | Manchester UnitedManchester Un | 0 - 1 | ArsenalArsenal |
| 01 Nov 20 | r07 | TottenhamTottenham | 2 - 1 | BrightonBrighton |
| 02 Nov 20 | r07 | FulhamFulham | 2 - 0 | West BromWest Brom |
| 02 Nov 20 | r07 | LeedsLeeds | 1 - 4 | LeicesterLeicester |
| |
| 06 Nov 20 | r08 | BrightonBrighton | 0 - 0 | BurnleyBurnley |
| 06 Nov 20 | r08 | SouthamptonSouthampton | 2 - 0 | NewcastleNewcastle |
| 07 Nov 20 | r08 | EvertonEverton | 1 - 3 | Manchester UnitedManchester Un |
| 07 Nov 20 | r08 | Crystal PalaceCrystal Palac | 4 - 1 | LeedsLeeds |
| 07 Nov 20 | r08 | ChelseaChelsea | 4 - 1 | Sheffield UnitedSheffield Uni |
| 07 Nov 20 | r08 | West HamWest Ham | 1 - 0 | FulhamFulham |
| 08 Nov 20 | r08 | West BromWest Brom | 0 - 1 | TottenhamTottenham |
| 08 Nov 20 | r08 | LeicesterLeicester | 1 - 0 | WolvesWolves |
| 08 Nov 20 | r08 | Manchester CityManchester Ci | 1 - 1 | LiverpoolLiverpool |
| 08 Nov 20 | r08 | ArsenalArsenal | 0 - 3 | Aston VillaAston Villa |
| |
| 21 Nov 20 | r09 | NewcastleNewcastle | 0 - 2 | ChelseaChelsea |
| 21 Nov 20 | r09 | Aston VillaAston Villa | 1 - 2 | BrightonBrighton |
| 21 Nov 20 | r09 | TottenhamTottenham | 2 - 0 | Manchester CityManchester Ci |
| 21 Nov 20 | r09 | Manchester UnitedManchester Un | 1 - 0 | West BromWest Brom |
| 22 Nov 20 | r09 | FulhamFulham | 2 - 3 | EvertonEverton |
| 22 Nov 20 | r09 | Sheffield UnitedSheffield Uni | 0 - 1 | West HamWest Ham |
| 22 Nov 20 | r09 | LeedsLeeds | 0 - 0 | ArsenalArsenal |
| 22 Nov 20 | r09 | LiverpoolLiverpool | 3 - 0 | LeicesterLeicester |
| 23 Nov 20 | r09 | BurnleyBurnley | 1 - 0 | Crystal PalaceCrystal Palac |
| 23 Nov 20 | r09 | WolvesWolves | 1 - 1 | SouthamptonSouthampton |
| |
| 27 Nov 20 | r10 | Crystal PalaceCrystal Palac | 0 - 2 | NewcastleNewcastle |
| 28 Nov 20 | r10 | BrightonBrighton | 1 - 1 | LiverpoolLiverpool |
| 28 Nov 20 | r10 | Manchester CityManchester Ci | 5 - 0 | BurnleyBurnley |
| 28 Nov 20 | r10 | EvertonEverton | 0 - 1 | LeedsLeeds |
| 28 Nov 20 | r10 | West BromWest Brom | 1 - 0 | Sheffield UnitedSheffield Uni |
| 29 Nov 20 | r10 | SouthamptonSouthampton | 2 - 3 | Manchester UnitedManchester Un |
| 29 Nov 20 | r10 | ChelseaChelsea | 0 - 0 | TottenhamTottenham |
| 29 Nov 20 | r10 | ArsenalArsenal | 1 - 2 | WolvesWolves |
| 30 Nov 20 | r10 | LeicesterLeicester | 1 - 2 | FulhamFulham |
| 30 Nov 20 | r10 | West HamWest Ham | 2 - 1 | Aston VillaAston Villa |
| |
| 05 Dec 20 | r11 | BurnleyBurnley | 1 - 1 | EvertonEverton |
| 05 Dec 20 | r11 | Manchester CityManchester Ci | 2 - 0 | FulhamFulham |
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