| 12 Sep 20 | r01        | FulhamFulham | 0 - 3 | ArsenalArsenal |
| 12 Sep 20 | r01        | Crystal PalaceCrystal Palac | 1 - 0 | SouthamptonSouthampton |
| 12 Sep 20 | r01        | LiverpoolLiverpool | 4 - 3 | LeedsLeeds |
| 12 Sep 20 | r01        | West HamWest Ham | 0 - 2 | NewcastleNewcastle |
| 13 Sep 20 | r01        | West BromWest Brom | 0 - 3 | LeicesterLeicester |
| 13 Sep 20 | r01        | TottenhamTottenham | 0 - 1 | EvertonEverton |
| 14 Sep 20 | r01        | Sheffield UnitedSheffield Uni | 0 - 2 | WolvesWolves |
| 14 Sep 20 | r01        | BrightonBrighton | 1 - 3 | ChelseaChelsea |
| |
| 19 Sep 20 | r02        | EvertonEverton | 5 - 2 | West BromWest Brom |
| 19 Sep 20 | r02        | LeedsLeeds | 4 - 3 | FulhamFulham |
| 19 Sep 20 | r02        | Manchester UnitedManchester Un | 1 - 3 | Crystal PalaceCrystal Palac |
| 19 Sep 20 | r02        | ArsenalArsenal | 2 - 1 | West HamWest Ham |
| 20 Sep 20 | r02        | SouthamptonSouthampton | 2 - 5 | TottenhamTottenham |
| 20 Sep 20 | r02        | NewcastleNewcastle | 0 - 3 | BrightonBrighton |
| 20 Sep 20 | r02        | ChelseaChelsea | 0 - 2 | LiverpoolLiverpool |
| 20 Sep 20 | r02        | LeicesterLeicester | 4 - 2 | BurnleyBurnley |
| 21 Sep 20 | r02        | Aston VillaAston Villa | 1 - 0 | Sheffield UnitedSheffield Uni |
| 21 Sep 20 | r02        | WolvesWolves | 1 - 3 | Manchester CityManchester Ci |
| |
| 26 Sep 20 | r03        | BrightonBrighton | 2 - 3 | Manchester UnitedManchester Un |
| 26 Sep 20 | r03        | Crystal PalaceCrystal Palac | 1 - 2 | EvertonEverton |
| 26 Sep 20 | r03        | West BromWest Brom | 3 - 3 | ChelseaChelsea |
| 26 Sep 20 | r03        | BurnleyBurnley | 0 - 1 | SouthamptonSouthampton |
| 27 Sep 20 | r03        | Sheffield UnitedSheffield Uni | 0 - 1 | LeedsLeeds |
| 27 Sep 20 | r03        | TottenhamTottenham | 1 - 1 | NewcastleNewcastle |
| 27 Sep 20 | r03        | Manchester CityManchester Ci | 2 - 5 | LeicesterLeicester |
| 27 Sep 20 | r03        | West HamWest Ham | 4 - 0 | WolvesWolves |
| 28 Sep 20 | r03        | FulhamFulham | 0 - 3 | Aston VillaAston Villa |
| 28 Sep 20 | r03        | LiverpoolLiverpool | 3 - 1 | ArsenalArsenal |
| |
| 03 Oct 20 | r04        | ChelseaChelsea | 4 - 0 | Crystal PalaceCrystal Palac |
| 03 Oct 20 | r04        | EvertonEverton | 4 - 2 | BrightonBrighton |
| 03 Oct 20 | r04        | LeedsLeeds | 1 - 1 | Manchester CityManchester Ci |
| 03 Oct 20 | r04        | NewcastleNewcastle | 3 - 1 | BurnleyBurnley |
| 04 Oct 20 | r04        | LeicesterLeicester | 0 - 3 | West HamWest Ham |
| 04 Oct 20 | r04        | SouthamptonSouthampton | 2 - 0 | West BromWest Brom |
| 04 Oct 20 | r04        | ArsenalArsenal | 2 - 1 | Sheffield UnitedSheffield Uni |
| 04 Oct 20 | r04        | WolvesWolves | 1 - 0 | FulhamFulham |
| 04 Oct 20 | r04        | Manchester UnitedManchester Un | 1 - 6 | TottenhamTottenham |
| 04 Oct 20 | r04        | Aston VillaAston Villa | 7 - 2 | LiverpoolLiverpool |
| |
| 17 Oct 20 | r05        | EvertonEverton | 2 - 2 | LiverpoolLiverpool |
| 17 Oct 20 | r05        | ChelseaChelsea | 3 - 3 | SouthamptonSouthampton |
| 17 Oct 20 | r05        | Manchester CityManchester Ci | 1 - 0 | ArsenalArsenal |
| 17 Oct 20 | r05        | NewcastleNewcastle | 1 - 4 | Manchester UnitedManchester Un |
| 18 Oct 20 | r05        | Sheffield UnitedSheffield Uni | 1 - 1 | FulhamFulham |
| 18 Oct 20 | r05        | Crystal PalaceCrystal Palac | 1 - 1 | BrightonBrighton |
| 18 Oct 20 | r05        | TottenhamTottenham | 3 - 3 | West HamWest Ham |
| 18 Oct 20 | r05        | LeicesterLeicester | 0 - 1 | Aston VillaAston Villa |
| 19 Oct 20 | r05        | West BromWest Brom | 0 - 0 | BurnleyBurnley |
| 19 Oct 20 | r05        | LeedsLeeds | 0 - 1 | WolvesWolves |
| |
| 23 Oct 20 | r06        | Aston VillaAston Villa | 0 - 3 | LeedsLeeds |
| 24 Oct 20 | r06        | West HamWest Ham | 1 - 1 | Manchester CityManchester Ci |
| 24 Oct 20 | r06        | FulhamFulham | 1 - 2 | Crystal PalaceCrystal Palac |
| 24 Oct 20 | r06        | Manchester UnitedManchester Un | 0 - 0 | ChelseaChelsea |
| 24 Oct 20 | r06        | LiverpoolLiverpool | 2 - 1 | Sheffield UnitedSheffield Uni |
| 25 Oct 20 | r06        | SouthamptonSouthampton | 2 - 0 | EvertonEverton |
| 25 Oct 20 | r06        | WolvesWolves | 1 - 1 | NewcastleNewcastle |
| 25 Oct 20 | r06        | ArsenalArsenal | 0 - 1 | LeicesterLeicester |
| 26 Oct 20 | r06        | BrightonBrighton | 1 - 1 | West BromWest Brom |
| 26 Oct 20 | r06        | BurnleyBurnley | 0 - 1 | TottenhamTottenham |
| |
| 30 Oct 20 | r07        | WolvesWolves | 2 - 0 | Crystal PalaceCrystal Palac |
| 31 Oct 20 | r07        | Sheffield UnitedSheffield Uni | 0 - 1 | Manchester CityManchester Ci |
| 31 Oct 20 | r07        | BurnleyBurnley | 0 - 3 | ChelseaChelsea |
| 31 Oct 20 | r07        | LiverpoolLiverpool | 2 - 1 | West HamWest Ham |
| 01 Nov 20 | r07        | Aston VillaAston Villa | 3 - 4 | SouthamptonSouthampton |
| 01 Nov 20 | r07        | NewcastleNewcastle | 2 - 1 | EvertonEverton |
| 01 Nov 20 | r07        | Manchester UnitedManchester Un | 0 - 1 | ArsenalArsenal |
| 01 Nov 20 | r07        | TottenhamTottenham | 2 - 1 | BrightonBrighton |
| 02 Nov 20 | r07        | FulhamFulham | 2 - 0 | West BromWest Brom |
| 02 Nov 20 | r07        | LeedsLeeds | 1 - 4 | LeicesterLeicester |
| |
| 06 Nov 20 | r08        | BrightonBrighton | 0 - 0 | BurnleyBurnley |
| 06 Nov 20 | r08        | SouthamptonSouthampton | 2 - 0 | NewcastleNewcastle |
| 07 Nov 20 | r08        | EvertonEverton | 1 - 3 | Manchester UnitedManchester Un |
| 07 Nov 20 | r08        | Crystal PalaceCrystal Palac | 4 - 1 | LeedsLeeds |
| 07 Nov 20 | r08        | ChelseaChelsea | 4 - 1 | Sheffield UnitedSheffield Uni |
| 07 Nov 20 | r08        | West HamWest Ham | 1 - 0 | FulhamFulham |
| 08 Nov 20 | r08        | West BromWest Brom | 0 - 1 | TottenhamTottenham |
| 08 Nov 20 | r08        | LeicesterLeicester | 1 - 0 | WolvesWolves |
| 08 Nov 20 | r08        | Manchester CityManchester Ci | 1 - 1 | LiverpoolLiverpool |
| 08 Nov 20 | r08        | ArsenalArsenal | 0 - 3 | Aston VillaAston Villa |
| |
| 21 Nov 20 | r09        | NewcastleNewcastle | 0 - 2 | ChelseaChelsea |
| 21 Nov 20 | r09        | Aston VillaAston Villa | 1 - 2 | BrightonBrighton |
| 21 Nov 20 | r09        | TottenhamTottenham | 2 - 0 | Manchester CityManchester Ci |
| 21 Nov 20 | r09        | Manchester UnitedManchester Un | 1 - 0 | West BromWest Brom |
| 22 Nov 20 | r09        | FulhamFulham | 2 - 3 | EvertonEverton |
| 22 Nov 20 | r09        | Sheffield UnitedSheffield Uni | 0 - 1 | West HamWest Ham |
| 22 Nov 20 | r09        | LeedsLeeds | 0 - 0 | ArsenalArsenal |
| 22 Nov 20 | r09        | LiverpoolLiverpool | 3 - 0 | LeicesterLeicester |
| 23 Nov 20 | r09        | BurnleyBurnley | 1 - 0 | Crystal PalaceCrystal Palac |
| 23 Nov 20 | r09        | WolvesWolves | 1 - 1 | SouthamptonSouthampton |
| |
| 27 Nov 20 | r10        | Crystal PalaceCrystal Palac | 0 - 2 | NewcastleNewcastle |
| 28 Nov 20 | r10        | BrightonBrighton | 1 - 1 | LiverpoolLiverpool |
| 28 Nov 20 | r10        | Manchester CityManchester Ci | 5 - 0 | BurnleyBurnley |
| 28 Nov 20 | r10        | EvertonEverton | 0 - 1 | LeedsLeeds |
| 28 Nov 20 | r10        | West BromWest Brom | 1 - 0 | Sheffield UnitedSheffield Uni |
| 29 Nov 20 | r10        | SouthamptonSouthampton | 2 - 3 | Manchester UnitedManchester Un |
| 29 Nov 20 | r10        | ChelseaChelsea | 0 - 0 | TottenhamTottenham |
| 29 Nov 20 | r10        | ArsenalArsenal | 1 - 2 | WolvesWolves |
| 30 Nov 20 | r10        | LeicesterLeicester | 1 - 2 | FulhamFulham |
| 30 Nov 20 | r10        | West HamWest Ham | 2 - 1 | Aston VillaAston Villa |
| |
| 05 Dec 20 | r11        | BurnleyBurnley | 1 - 1 | EvertonEverton |
| 05 Dec 20 | r11        | Manchester CityManchester Ci | 2 - 0 | FulhamFulham |