| 15 Aug 08 | r00        | ArsenalArsenal | 1 - 0 | West BromWest Brom |
| 15 Aug 08 | r00        | BoltonBolton | 3 - 1 | StokeStoke |
| 15 Aug 08 | r00        | EvertonEverton | 2 - 3 | BlackburnBlackburn |
| 15 Aug 08 | r00        | HullHull | 2 - 1 | FulhamFulham |
| 15 Aug 08 | r00        | MiddlesbroughMiddlesbrough | 2 - 1 | TottenhamTottenham |
| 15 Aug 08 | r00        | SunderlandSunderland | 0 - 1 | LiverpoolLiverpool |
| 15 Aug 08 | r00        | West HamWest Ham | 2 - 1 | WiganWigan |
| 16 Aug 08 | r00        | Aston VillaAston Villa | 4 - 2 | Manchester CityManchester Ci |
| 16 Aug 08 | r00        | ChelseaChelsea | 4 - 0 | PortsmouthPortsmouth |
| 16 Aug 08 | r00        | Manchester UnitedManchester Un | 1 - 1 | NewcastleNewcastle |
| 22 Aug 08 | r00        | BlackburnBlackburn | 1 - 1 | HullHull |
| 22 Aug 08 | r00        | FulhamFulham | 1 - 0 | ArsenalArsenal |
| 22 Aug 08 | r00        | LiverpoolLiverpool | 2 - 1 | MiddlesbroughMiddlesbrough |
| 22 Aug 08 | r00        | NewcastleNewcastle | 1 - 0 | BoltonBolton |
| 22 Aug 08 | r00        | StokeStoke | 3 - 2 | Aston VillaAston Villa |
| 22 Aug 08 | r00        | TottenhamTottenham | 1 - 2 | SunderlandSunderland |
| 22 Aug 08 | r00        | West BromWest Brom | 1 - 2 | EvertonEverton |
| 23 Aug 08 | r00        | Manchester CityManchester Ci | 3 - 0 | West HamWest Ham |
| 23 Aug 08 | r00        | WiganWigan | 0 - 1 | ChelseaChelsea |
| 24 Aug 08 | r00        | PortsmouthPortsmouth | 0 - 1 | Manchester UnitedManchester Un |
| 29 Aug 08 | r00        | ArsenalArsenal | 3 - 0 | NewcastleNewcastle |
| 29 Aug 08 | r00        | BoltonBolton | 0 - 0 | West BromWest Brom |
| 29 Aug 08 | r00        | EvertonEverton | 0 - 3 | PortsmouthPortsmouth |
| 29 Aug 08 | r00        | HullHull | 0 - 5 | WiganWigan |
| 29 Aug 08 | r00        | MiddlesbroughMiddlesbrough | 2 - 1 | StokeStoke |
| 29 Aug 08 | r00        | West HamWest Ham | 4 - 1 | BlackburnBlackburn |
| 30 Aug 08 | r00        | Aston VillaAston Villa | 0 - 0 | LiverpoolLiverpool |
| 30 Aug 08 | r00        | ChelseaChelsea | 1 - 1 | TottenhamTottenham |
| 30 Aug 08 | r00        | SunderlandSunderland | 0 - 3 | Manchester CityManchester Ci |
| 12 Sep 08 | r00        | BlackburnBlackburn | 0 - 4 | ArsenalArsenal |
| 12 Sep 08 | r00        | FulhamFulham | 2 - 1 | BoltonBolton |
| 12 Sep 08 | r00        | LiverpoolLiverpool | 2 - 1 | Manchester UnitedManchester Un |
| 12 Sep 08 | r00        | Manchester CityManchester Ci | 1 - 3 | ChelseaChelsea |
| 12 Sep 08 | r00        | NewcastleNewcastle | 1 - 2 | HullHull |
| 12 Sep 08 | r00        | PortsmouthPortsmouth | 2 - 1 | MiddlesbroughMiddlesbrough |
| 12 Sep 08 | r00        | West BromWest Brom | 3 - 2 | West HamWest Ham |
| 12 Sep 08 | r00        | WiganWigan | 1 - 1 | SunderlandSunderland |
| 13 Sep 08 | r00        | StokeStoke | 2 - 3 | EvertonEverton |
| 14 Sep 08 | r00        | TottenhamTottenham | 1 - 2 | Aston VillaAston Villa |
| 19 Sep 08 | r00        | BlackburnBlackburn | 1 - 0 | FulhamFulham |
| 19 Sep 08 | r00        | BoltonBolton | 1 - 3 | ArsenalArsenal |
| 19 Sep 08 | r00        | LiverpoolLiverpool | 0 - 0 | StokeStoke |
| 19 Sep 08 | r00        | SunderlandSunderland | 2 - 0 | MiddlesbroughMiddlesbrough |
| 19 Sep 08 | r00        | West HamWest Ham | 3 - 1 | NewcastleNewcastle |
| 20 Sep 08 | r00        | ChelseaChelsea | 1 - 1 | Manchester UnitedManchester Un |
| 20 Sep 08 | r00        | HullHull | 2 - 2 | EvertonEverton |
| 20 Sep 08 | r00        | Manchester CityManchester Ci | 6 - 0 | PortsmouthPortsmouth |
| 20 Sep 08 | r00        | TottenhamTottenham | 0 - 0 | WiganWigan |
| 20 Sep 08 | r00        | West BromWest Brom | 1 - 2 | Aston VillaAston Villa |
| 26 Sep 08 | r00        | ArsenalArsenal | 1 - 2 | HullHull |
| 26 Sep 08 | r00        | Aston VillaAston Villa | 2 - 1 | SunderlandSunderland |
| 26 Sep 08 | r00        | EvertonEverton | 0 - 2 | LiverpoolLiverpool |
| 26 Sep 08 | r00        | FulhamFulham | 1 - 2 | West HamWest Ham |
| 26 Sep 08 | r00        | Manchester UnitedManchester Un | 2 - 0 | BoltonBolton |
| 26 Sep 08 | r00        | MiddlesbroughMiddlesbrough | 0 - 1 | West BromWest Brom |
| 26 Sep 08 | r00        | NewcastleNewcastle | 1 - 2 | BlackburnBlackburn |
| 26 Sep 08 | r00        | StokeStoke | 0 - 2 | ChelseaChelsea |
| 27 Sep 08 | r00        | PortsmouthPortsmouth | 2 - 0 | TottenhamTottenham |
| 27 Sep 08 | r00        | WiganWigan | 2 - 1 | Manchester CityManchester Ci |
| 03 Oct 08 | r00        | SunderlandSunderland | 1 - 1 | ArsenalArsenal |
| 03 Oct 08 | r00        | West BromWest Brom | 1 - 0 | FulhamFulham |
| 03 Oct 08 | r00        | WiganWigan | 0 - 1 | MiddlesbroughMiddlesbrough |
| 04 Oct 08 | r00        | ChelseaChelsea | 2 - 0 | Aston VillaAston Villa |
| 04 Oct 08 | r00        | EvertonEverton | 2 - 2 | NewcastleNewcastle |
| 04 Oct 08 | r00        | Manchester CityManchester Ci | 2 - 3 | LiverpoolLiverpool |
| 04 Oct 08 | r00        | PortsmouthPortsmouth | 2 - 1 | StokeStoke |
| 04 Oct 08 | r00        | TottenhamTottenham | 0 - 1 | HullHull |
| 04 Oct 08 | r00        | West HamWest Ham | 1 - 3 | BoltonBolton |
| 04 Oct 08 | r07        | BlackburnBlackburn | 0 - 2 | Manchester UnitedManchester Un |
| |
| 17 Oct 08 | r00        | ArsenalArsenal | 3 - 1 | EvertonEverton |
| 17 Oct 08 | r00        | Aston VillaAston Villa | 0 - 0 | PortsmouthPortsmouth |
| 17 Oct 08 | r00        | BoltonBolton | 0 - 0 | BlackburnBlackburn |
| 17 Oct 08 | r00        | FulhamFulham | 0 - 0 | SunderlandSunderland |
| 17 Oct 08 | r00        | LiverpoolLiverpool | 3 - 2 | WiganWigan |
| 17 Oct 08 | r00        | Manchester UnitedManchester Un | 4 - 0 | West BromWest Brom |
| 17 Oct 08 | r00        | MiddlesbroughMiddlesbrough | 0 - 5 | ChelseaChelsea |
| 18 Oct 08 | r00        | HullHull | 1 - 0 | West HamWest Ham |
| 18 Oct 08 | r00        | StokeStoke | 2 - 1 | TottenhamTottenham |
| 19 Oct 08 | r00        | NewcastleNewcastle | 2 - 2 | Manchester CityManchester Ci |
| 24 Oct 08 | r00        | BlackburnBlackburn | 1 - 1 | MiddlesbroughMiddlesbrough |
| 24 Oct 08 | r00        | EvertonEverton | 1 - 1 | Manchester UnitedManchester Un |
| 24 Oct 08 | r00        | SunderlandSunderland | 2 - 1 | NewcastleNewcastle |
| 24 Oct 08 | r00        | West BromWest Brom | 0 - 3 | HullHull |
| 25 Oct 08 | r00        | ChelseaChelsea | 0 - 1 | LiverpoolLiverpool |
| 25 Oct 08 | r00        | Manchester CityManchester Ci | 3 - 0 | StokeStoke |
| 25 Oct 08 | r00        | PortsmouthPortsmouth | 1 - 1 | FulhamFulham |
| 25 Oct 08 | r00        | TottenhamTottenham | 2 - 0 | BoltonBolton |
| 25 Oct 08 | r00        | West HamWest Ham | 0 - 2 | ArsenalArsenal |
| 25 Oct 08 | r00        | WiganWigan | 0 - 4 | Aston VillaAston Villa |
| 27 Oct 08 | r00        | NewcastleNewcastle | 2 - 1 | West BromWest Brom |
| 28 Oct 08 | r10        | ArsenalArsenal | 4 - 4 | TottenhamTottenham |
| |
| 28 Oct 08 | r00        | Aston VillaAston Villa | 3 - 2 | BlackburnBlackburn |
| 28 Oct 08 | r00        | BoltonBolton | 0 - 1 | EvertonEverton |
| 28 Oct 08 | r00        | FulhamFulham | 2 - 0 | WiganWigan |
| 28 Oct 08 | r00        | HullHull | 0 - 3 | ChelseaChelsea |
| 28 Oct 08 | r00        | LiverpoolLiverpool | 1 - 0 | PortsmouthPortsmouth |
| 28 Oct 08 | r00        | Manchester UnitedManchester Un | 2 - 0 | West HamWest Ham |
| 28 Oct 08 | r00        | MiddlesbroughMiddlesbrough | 2 - 0 | Manchester CityManchester Ci |
| 28 Oct 08 | r00        | StokeStoke | 1 - 0 | SunderlandSunderland |
| 31 Oct 08 | r00        | ChelseaChelsea | 5 - 0 | SunderlandSunderland |