| 18 Aug 00 | r00        | CharltonCharlton | 4 - 0 | Manchester CityManchester Ci |
| 22 Aug 00 | r00        | Manchester CityManchester Ci | 4 - 2 | SunderlandSunderland |
| 25 Aug 00 | r00        | Manchester CityManchester Ci | 1 - 2 | CoventryCoventry |
| 04 Sep 00 | r00        | LeedsLeeds | 1 - 2 | Manchester CityManchester Ci |
| 08 Sep 00 | r00        | LiverpoolLiverpool | 3 - 2 | Manchester CityManchester Ci |
| 16 Sep 00 | r00        | Manchester CityManchester Ci | 1 - 1 | MiddlesbroughMiddlesbrough |
| 22 Sep 00 | r00        | TottenhamTottenham | 0 - 0 | Manchester CityManchester Ci |
| 29 Sep 00 | r00        | Manchester CityManchester Ci | 0 - 1 | NewcastleNewcastle |
| 13 Oct 00 | r00        | Manchester CityManchester Ci | 2 - 0 | BradfordBradford |
| 22 Oct 00 | r00        | SouthamptonSouthampton | 0 - 2 | Manchester CityManchester Ci |
| 27 Oct 00 | r00        | ArsenalArsenal | 5 - 0 | Manchester CityManchester Ci |
| 03 Nov 00 | r00        | Manchester CityManchester Ci | 0 - 1 | LeicesterLeicester |
| 10 Nov 00 | r00        | West HamWest Ham | 4 - 1 | Manchester CityManchester Ci |
| 17 Nov 00 | r00        | Manchester CityManchester Ci | 0 - 1 | Manchester UnitedManchester Un |
| 24 Nov 00 | r00        | Manchester CityManchester Ci | 2 - 3 | IpswichIpswich |
| 02 Dec 00 | r00        | ChelseaChelsea | 2 - 1 | Manchester CityManchester Ci |
| 08 Dec 00 | r00        | Manchester CityManchester Ci | 5 - 0 | EvertonEverton |
| 15 Dec 00 | r00        | Aston VillaAston Villa | 2 - 2 | Manchester CityManchester Ci |
| 22 Dec 00 | r00        | SunderlandSunderland | 1 - 0 | Manchester CityManchester Ci |
| 25 Dec 00 | r00        | Manchester CityManchester Ci | 0 - 0 | DerbyDerby |
| 29 Dec 00 | r00        | Manchester CityManchester Ci | 1 - 4 | CharltonCharlton |
| 31 Dec 00 | r00        | CoventryCoventry | 1 - 1 | Manchester CityManchester Ci |
| 12 Jan 01 | r00        | Manchester CityManchester Ci | 0 - 4 | LeedsLeeds |
| 19 Jan 01 | r00        | DerbyDerby | 1 - 1 | Manchester CityManchester Ci |
| 30 Jan 01 | r00        | Manchester CityManchester Ci | 1 - 1 | LiverpoolLiverpool |
| 02 Feb 01 | r00        | MiddlesbroughMiddlesbrough | 1 - 1 | Manchester CityManchester Ci |
| 09 Feb 01 | r00        | Manchester CityManchester Ci | 0 - 1 | TottenhamTottenham |
| 23 Feb 01 | r00        | NewcastleNewcastle | 0 - 1 | Manchester CityManchester Ci |
| 02 Mar 01 | r00        | Manchester CityManchester Ci | 0 - 1 | SouthamptonSouthampton |
| 16 Mar 01 | r00        | BradfordBradford | 2 - 2 | Manchester CityManchester Ci |
| 30 Mar 01 | r00        | Manchester CityManchester Ci | 1 - 3 | Aston VillaAston Villa |
| 07 Apr 01 | r00        | EvertonEverton | 3 - 1 | Manchester CityManchester Ci |
| 10 Apr 01 | r00        | Manchester CityManchester Ci | 0 - 4 | ArsenalArsenal |
| 13 Apr 01 | r00        | LeicesterLeicester | 1 - 2 | Manchester CityManchester Ci |
| 20 Apr 01 | r00        | Manchester UnitedManchester Un | 1 - 1 | Manchester CityManchester Ci |
| 27 Apr 01 | r00        | Manchester CityManchester Ci | 1 - 0 | West HamWest Ham |
| 06 May 01 | r00        | IpswichIpswich | 2 - 1 | Manchester CityManchester Ci |
| 18 May 01 | r00        | Manchester CityManchester Ci | 1 - 2 | ChelseaChelsea |