| 18 Aug 00 | r00  | CharltonCharlton | 4 - 0 | Manchester CityManchester Ci |
| 18 Aug 00 | r00 | ChelseaChelsea | 4 - 2 | West HamWest Ham |
| 18 Aug 00 | r00 | CoventryCoventry | 1 - 3 | MiddlesbroughMiddlesbrough |
| 18 Aug 00 | r00 | DerbyDerby | 2 - 2 | SouthamptonSouthampton |
| 18 Aug 00 | r00 | LeedsLeeds | 2 - 0 | EvertonEverton |
| 18 Aug 00 | r00 | LeicesterLeicester | 0 - 0 | Aston VillaAston Villa |
| 18 Aug 00 | r00 | LiverpoolLiverpool | 1 - 0 | BradfordBradford |
| 18 Aug 00 | r00 | SunderlandSunderland | 1 - 0 | ArsenalArsenal |
| 18 Aug 00 | r00 | TottenhamTottenham | 3 - 1 | IpswichIpswich |
| 19 Aug 00 | r00 | Manchester UnitedManchester Un | 2 - 0 | NewcastleNewcastle |
| 20 Aug 00 | r00 | ArsenalArsenal | 2 - 0 | LiverpoolLiverpool |
| 21 Aug 00 | r00 | BradfordBradford | 2 - 0 | ChelseaChelsea |
| 21 Aug 00 | r00 | IpswichIpswich | 1 - 1 | Manchester UnitedManchester Un |
| 21 Aug 00 | r00 | MiddlesbroughMiddlesbrough | 1 - 1 | TottenhamTottenham |
| 22 Aug 00 | r00 | EvertonEverton | 3 - 0 | CharltonCharlton |
| 22 Aug 00 | r00 | Manchester CityManchester Ci | 4 - 2 | SunderlandSunderland |
| 22 Aug 00 | r00 | NewcastleNewcastle | 3 - 2 | DerbyDerby |
| 22 Aug 00 | r00 | SouthamptonSouthampton | 1 - 2 | CoventryCoventry |
| 22 Aug 00 | r00 | West HamWest Ham | 0 - 1 | LeicesterLeicester |
| 25 Aug 00 | r00 | ArsenalArsenal | 5 - 3 | CharltonCharlton |
| 25 Aug 00 | r00 | BradfordBradford | 0 - 0 | LeicesterLeicester |
| 25 Aug 00 | r00 | EvertonEverton | 2 - 2 | DerbyDerby |
| 25 Aug 00 | r00 | IpswichIpswich | 1 - 0 | SunderlandSunderland |
| 25 Aug 00 | r00 | Manchester CityManchester Ci | 1 - 2 | CoventryCoventry |
| 25 Aug 00 | r00 | MiddlesbroughMiddlesbrough | 1 - 2 | LeedsLeeds |
| 25 Aug 00 | r00 | NewcastleNewcastle | 2 - 0 | TottenhamTottenham |
| 25 Aug 00 | r00 | SouthamptonSouthampton | 3 - 3 | LiverpoolLiverpool |
| 25 Aug 00 | r00 | West HamWest Ham | 2 - 2 | Manchester UnitedManchester Un |
| 26 Aug 00 | r00 | Aston VillaAston Villa | 1 - 1 | ChelseaChelsea |
| 04 Sep 00 | r00 | LeedsLeeds | 1 - 2 | Manchester CityManchester Ci |
| 04 Sep 00 | r00 | Manchester UnitedManchester Un | 6 - 0 | BradfordBradford |
| 04 Sep 00 | r00 | SunderlandSunderland | 1 - 1 | West HamWest Ham |
| 04 Sep 00 | r00 | TottenhamTottenham | 3 - 2 | EvertonEverton |
| 05 Sep 00 | r00 | CharltonCharlton | 1 - 1 | SouthamptonSouthampton |
| 05 Sep 00 | r00 | ChelseaChelsea | 2 - 2 | ArsenalArsenal |
| 05 Sep 00 | r00 | CoventryCoventry | 0 - 2 | NewcastleNewcastle |
| 05 Sep 00 | r00 | DerbyDerby | 3 - 3 | MiddlesbroughMiddlesbrough |
| 05 Sep 00 | r00 | LeicesterLeicester | 2 - 1 | IpswichIpswich |
| 05 Sep 00 | r00 | LiverpoolLiverpool | 3 - 1 | Aston VillaAston Villa |
| 08 Sep 00 | r00 | BradfordBradford | 1 - 1 | ArsenalArsenal |
| 08 Sep 00 | r00 | CoventryCoventry | 0 - 0 | LeedsLeeds |
| 08 Sep 00 | r00 | IpswichIpswich | 1 - 2 | Aston VillaAston Villa |
| 08 Sep 00 | r00 | LeicesterLeicester | 1 - 0 | SouthamptonSouthampton |
| 08 Sep 00 | r00 | LiverpoolLiverpool | 3 - 2 | Manchester CityManchester Ci |
| 08 Sep 00 | r00 | Manchester UnitedManchester Un | 3 - 0 | SunderlandSunderland |
| 08 Sep 00 | r00 | MiddlesbroughMiddlesbrough | 1 - 2 | EvertonEverton |
| 08 Sep 00 | r00 | NewcastleNewcastle | 0 - 0 | ChelseaChelsea |
| 09 Sep 00 | r00 | DerbyDerby | 2 - 2 | CharltonCharlton |
| 10 Sep 00 | r00 | TottenhamTottenham | 1 - 0 | West HamWest Ham |
| 15 Sep 00 | r00 | ArsenalArsenal | 2 - 1 | CoventryCoventry |
| 15 Sep 00 | r00 | Aston VillaAston Villa | 2 - 0 | BradfordBradford |
| 15 Sep 00 | r00 | CharltonCharlton | 1 - 0 | TottenhamTottenham |
| 15 Sep 00 | r00 | EvertonEverton | 1 - 3 | Manchester UnitedManchester Un |
| 15 Sep 00 | r00 | LeedsLeeds | 1 - 2 | IpswichIpswich |
| 15 Sep 00 | r00 | SouthamptonSouthampton | 2 - 0 | NewcastleNewcastle |
| 15 Sep 00 | r00 | SunderlandSunderland | 2 - 1 | DerbyDerby |
| 16 Sep 00 | r00 | ChelseaChelsea | 0 - 2 | LeicesterLeicester |
| 16 Sep 00 | r00 | Manchester CityManchester Ci | 1 - 1 | MiddlesbroughMiddlesbrough |
| 16 Sep 00 | r00 | West HamWest Ham | 1 - 1 | LiverpoolLiverpool |
| 22 Sep 00 | r00 | BradfordBradford | 0 - 1 | SouthamptonSouthampton |
| 22 Sep 00 | r00 | CoventryCoventry | 0 - 3 | West HamWest Ham |
| 22 Sep 00 | r00 | DerbyDerby | 1 - 1 | LeedsLeeds |
| 22 Sep 00 | r00 | IpswichIpswich | 1 - 1 | ArsenalArsenal |
| 22 Sep 00 | r00 | LiverpoolLiverpool | 1 - 1 | SunderlandSunderland |
| 22 Sep 00 | r00 | Manchester UnitedManchester Un | 3 - 3 | ChelseaChelsea |
| 22 Sep 00 | r00 | MiddlesbroughMiddlesbrough | 1 - 1 | Aston VillaAston Villa |
| 22 Sep 00 | r00 | NewcastleNewcastle | 0 - 1 | CharltonCharlton |
| 22 Sep 00 | r00 | TottenhamTottenham | 0 - 0 | Manchester CityManchester Ci |
| 23 Sep 00 | r00 | LeicesterLeicester | 1 - 1 | EvertonEverton |
| 29 Sep 00 | r00 | Aston VillaAston Villa | 4 - 1 | DerbyDerby |
| 29 Sep 00 | r00 | CharltonCharlton | 2 - 2 | CoventryCoventry |
| 29 Sep 00 | r00 | EvertonEverton | 0 - 3 | IpswichIpswich |
| 29 Sep 00 | r00 | LeedsLeeds | 4 - 3 | TottenhamTottenham |
| 29 Sep 00 | r00 | Manchester CityManchester Ci | 0 - 1 | NewcastleNewcastle |
| 29 Sep 00 | r00 | SouthamptonSouthampton | 1 - 3 | MiddlesbroughMiddlesbrough |
| 29 Sep 00 | r00 | West HamWest Ham | 1 - 1 | BradfordBradford |
| 30 Sep 00 | r00 | ArsenalArsenal | 1 - 0 | Manchester UnitedManchester Un |
| 30 Sep 00 | r00 | ChelseaChelsea | 3 - 0 | LiverpoolLiverpool |
| 30 Sep 00 | r00 | SunderlandSunderland | 0 - 0 | LeicesterLeicester |
| 13 Oct 00 | r00 | ArsenalArsenal | 1 - 0 | Aston VillaAston Villa |
| 13 Oct 00 | r00 | CoventryCoventry | 2 - 1 | TottenhamTottenham |
| 13 Oct 00 | r00 | EvertonEverton | 1 - 1 | SouthamptonSouthampton |
| 13 Oct 00 | r00 | IpswichIpswich | 1 - 1 | West HamWest Ham |
| 13 Oct 00 | r00 | LeedsLeeds | 3 - 1 | CharltonCharlton |
| 13 Oct 00 | r00 | LeicesterLeicester | 0 - 3 | Manchester UnitedManchester Un |
| 13 Oct 00 | r00 | Manchester CityManchester Ci | 2 - 0 | BradfordBradford |
| 13 Oct 00 | r00 | SunderlandSunderland | 1 - 0 | ChelseaChelsea |
| 14 Oct 00 | r00 | DerbyDerby | 0 - 4 | LiverpoolLiverpool |
| 15 Oct 00 | r00 | MiddlesbroughMiddlesbrough | 1 - 3 | NewcastleNewcastle |
| 20 Oct 00 | r00 | BradfordBradford | 0 - 2 | IpswichIpswich |
| 20 Oct 00 | r00 | CharltonCharlton | 1 - 0 | MiddlesbroughMiddlesbrough |
| 20 Oct 00 | r00 | ChelseaChelsea | 6 - 1 | CoventryCoventry |
| 20 Oct 00 | r00 | LiverpoolLiverpool | 1 - 0 | LeicesterLeicester |
| 20 Oct 00 | r00 | Manchester UnitedManchester Un | 3 - 0 | LeedsLeeds |
| 20 Oct 00 | r00 | NewcastleNewcastle | 0 - 1 | EvertonEverton |
| 20 Oct 00 | r00 | TottenhamTottenham | 3 - 1 | DerbyDerby |
| 20 Oct 00 | r00 | West HamWest Ham | 1 - 2 | ArsenalArsenal |
| 21 Oct 00 | r00 | Aston VillaAston Villa | 0 - 0 | SunderlandSunderland |
| 22 Oct 00 | r00 | SouthamptonSouthampton | 0 - 2 | Manchester CityManchester Ci |
| 27 Oct 00 | r00 | ArsenalArsenal | 5 - 0 | Manchester CityManchester Ci |
| 27 Oct 00 | r00 | Aston VillaAston Villa | 2 - 1 | CharltonCharlton |
| 27 Oct 00 | r00 | ChelseaChelsea | 3 - 0 | TottenhamTottenham |
| 27 Oct 00 | r00 | IpswichIpswich | 2 - 1 | MiddlesbroughMiddlesbrough |
| 27 Oct 00 | r00 | LeicesterLeicester | 2 - 1 | DerbyDerby |
| 27 Oct 00 | r00 | Manchester UnitedManchester Un | 5 - 0 | SouthamptonSouthampton |
| 27 Oct 00 | r00 | SunderlandSunderland | 1 - 0 | CoventryCoventry |
| 27 Oct 00 | r00 | West HamWest Ham | 1 - 0 | NewcastleNewcastle |
| 28 Oct 00 | r00 | BradfordBradford | 1 - 1 | LeedsLeeds |
| 28 Oct 00 | r00 | LiverpoolLiverpool | 3 - 1 | EvertonEverton |
| 03 Nov 00 | r00 | CharltonCharlton | 2 - 0 | BradfordBradford |
| 03 Nov 00 | r00 | CoventryCoventry | 1 - 2 | Manchester UnitedManchester Un |
| 03 Nov 00 | r00 | LeedsLeeds | 4 - 3 | LiverpoolLiverpool |
| 03 Nov 00 | r00 | Manchester CityManchester Ci | 0 - 1 | LeicesterLeicester |
| 03 Nov 00 | r00 | MiddlesbroughMiddlesbrough | 0 - 1 | ArsenalArsenal |
| 03 Nov 00 | r00 | NewcastleNewcastle | 2 - 1 | IpswichIpswich |
| 03 Nov 00 | r00 | SouthamptonSouthampton | 3 - 2 | ChelseaChelsea |
| 03 Nov 00 | r00 | TottenhamTottenham | 2 - 1 | SunderlandSunderland |
| 04 Nov 00 | r00 | EvertonEverton | 0 - 1 | Aston VillaAston Villa |
| 05 Nov 00 | r00 | DerbyDerby | 0 - 0 | West HamWest Ham |
| 10 Nov 00 | r00 | ArsenalArsenal | 0 - 0 | DerbyDerby |
| 10 Nov 00 | r00 | Aston VillaAston Villa | 2 - 0 | TottenhamTottenham |
| 10 Nov 00 | r00 | BradfordBradford | 0 - 1 | EvertonEverton |
| 10 Nov 00 | r00 | IpswichIpswich | 2 - 0 | CharltonCharlton |
| 10 Nov 00 | r00 | LeicesterLeicester | 1 - 1 | NewcastleNewcastle |
| 10 Nov 00 | r00 | Manchester UnitedManchester Un | 2 - 1 | MiddlesbroughMiddlesbrough |
| 10 Nov 00 | r00 | SunderlandSunderland | 2 - 2 | SouthamptonSouthampton |
| 10 Nov 00 | r00 | West HamWest Ham | 4 - 1 | Manchester CityManchester Ci |
| 11 Nov 00 | r00 | ChelseaChelsea | 1 - 1 | LeedsLeeds |
| 11 Nov 00 | r00 | LiverpoolLiverpool | 4 - 1 | CoventryCoventry |
| 17 Nov 00 | r00 | CharltonCharlton | 2 - 0 | ChelseaChelsea |
| 17 Nov 00 | r00 | DerbyDerby | 2 - 0 | BradfordBradford |
| 17 Nov 00 | r00 | EvertonEverton | 2 - 0 | ArsenalArsenal |
| 17 Nov 00 | r00 | LeedsLeeds | 0 - 1 | West HamWest Ham |
| 17 Nov 00 | r00 | Manchester CityManchester Ci | 0 - 1 | Manchester UnitedManchester Un |
| 17 Nov 00 | r00 | MiddlesbroughMiddlesbrough | 0 - 3 | LeicesterLeicester |
| 17 Nov 00 | r00 | NewcastleNewcastle | 1 - 2 | SunderlandSunderland |
| 17 Nov 00 | r00 | SouthamptonSouthampton | 2 - 0 | Aston VillaAston Villa |
| 18 Nov 00 | r00 | TottenhamTottenham | 2 - 1 | LiverpoolLiverpool |
| 19 Nov 00 | r00 | CoventryCoventry | 0 - 1 | IpswichIpswich |
| 24 Nov 00 | r00 | CharltonCharlton | 0 - 1 | SunderlandSunderland |
| 24 Nov 00 | r00 | CoventryCoventry | 1 - 1 | Aston VillaAston Villa |
| 24 Nov 00 | r00 | DerbyDerby | 0 - 3 | Manchester UnitedManchester Un |
| 24 Nov 00 | r00 | EvertonEverton | 2 - 1 | ChelseaChelsea |
| 24 Nov 00 | r00 | Manchester CityManchester Ci | 2 - 3 | IpswichIpswich |
| 24 Nov 00 | r00 | MiddlesbroughMiddlesbrough | 2 - 2 | BradfordBradford |
| 24 Nov 00 | r00 | SouthamptonSouthampton | 2 - 3 | West HamWest Ham |
| 24 Nov 00 | r00 | TottenhamTottenham | 3 - 0 | LeicesterLeicester |
| 25 Nov 00 | r00 | LeedsLeeds | 1 - 0 | ArsenalArsenal |
| 25 Nov 00 | r00 | NewcastleNewcastle | 2 - 1 | LiverpoolLiverpool |
| 01 Dec 00 | r00 | ArsenalArsenal | 1 - 0 | SouthamptonSouthampton |
| 01 Dec 00 | r00 | Aston VillaAston Villa | 1 - 1 | NewcastleNewcastle |
| 01 Dec 00 | r00 | BradfordBradford | 2 - 1 | CoventryCoventry |
| 01 Dec 00 | r00 | IpswichIpswich | 0 - 1 | DerbyDerby |
| 01 Dec 00 | r00 | LeicesterLeicester | 3 - 1 | LeedsLeeds |
| 01 Dec 00 | r00 | LiverpoolLiverpool | 3 - 0 | CharltonCharlton |
| 01 Dec 00 | r00 | Manchester UnitedManchester Un | 2 - 0 | TottenhamTottenham |
| 01 Dec 00 | r00 | West HamWest Ham | 1 - 0 | MiddlesbroughMiddlesbrough |
| 02 Dec 00 | r00 | ChelseaChelsea | 2 - 1 | Manchester CityManchester Ci |
| 03 Dec 00 | r00 | SunderlandSunderland | 2 - 0 | EvertonEverton |
| 08 Dec 00 | r00 | ArsenalArsenal | 5 - 0 | NewcastleNewcastle |
| 08 Dec 00 | r00 | BradfordBradford | 3 - 3 | TottenhamTottenham |
| 08 Dec 00 | r00 | CharltonCharlton | 3 - 3 | Manchester UnitedManchester Un |
| 08 Dec 00 | r00 | ChelseaChelsea | 4 - 1 | DerbyDerby |
| 08 Dec 00 | r00 | Manchester CityManchester Ci | 5 - 0 | EvertonEverton |
| 08 Dec 00 | r00 | SouthamptonSouthampton | 1 - 0 | LeedsLeeds |
| 08 Dec 00 | r00 | SunderlandSunderland | 1 - 0 | MiddlesbroughMiddlesbrough |
| 08 Dec 00 | r00 | West HamWest Ham | 1 - 1 | Aston VillaAston Villa |
| 09 Dec 00 | r00 | CoventryCoventry | 1 - 0 | LeicesterLeicester |
| 09 Dec 00 | r00 | LiverpoolLiverpool | 0 - 1 | IpswichIpswich |
| 15 Dec 00 | r00 | Aston VillaAston Villa | 2 - 2 | Manchester CityManchester Ci |
| 15 Dec 00 | r00 | DerbyDerby | 1 - 0 | CoventryCoventry |
| 15 Dec 00 | r00 | EvertonEverton | 1 - 1 | West HamWest Ham |
| 15 Dec 00 | r00 | IpswichIpswich | 3 - 1 | SouthamptonSouthampton |
| 15 Dec 00 | r00 | LeedsLeeds | 2 - 0 | SunderlandSunderland |
| 15 Dec 00 | r00 | LeicesterLeicester | 3 - 1 | CharltonCharlton |
| 15 Dec 00 | r00 | MiddlesbroughMiddlesbrough | 1 - 0 | ChelseaChelsea |
| 15 Dec 00 | r00 | NewcastleNewcastle | 2 - 1 | BradfordBradford |
| 16 Dec 00 | r00 | Manchester UnitedManchester Un | 0 - 1 | LiverpoolLiverpool |
| 17 Dec 00 | r00 | TottenhamTottenham | 1 - 1 | ArsenalArsenal |
| 21 Dec 00 | r00 | CoventryCoventry | 1 - 1 | SouthamptonSouthampton |
| 22 Dec 00 | r00 | CharltonCharlton | 1 - 0 | EvertonEverton |
| 22 Dec 00 | r00 | ChelseaChelsea | 3 - 0 | BradfordBradford |
| 22 Dec 00 | r00 | DerbyDerby | 2 - 0 | NewcastleNewcastle |
| 22 Dec 00 | r00 | LeedsLeeds | 1 - 2 | Aston VillaAston Villa |
| 22 Dec 00 | r00 | LeicesterLeicester | 2 - 1 | West HamWest Ham |
| 22 Dec 00 | r00 | LiverpoolLiverpool | 4 - 0 | ArsenalArsenal |
| 22 Dec 00 | r00 | Manchester UnitedManchester Un | 2 - 0 | IpswichIpswich |
| 22 Dec 00 | r00 | SunderlandSunderland | 1 - 0 | Manchester CityManchester Ci |
| 22 Dec 00 | r00 | TottenhamTottenham | 0 - 0 | MiddlesbroughMiddlesbrough |
| 25 Dec 00 | r00 | ArsenalArsenal | 6 - 1 | LeicesterLeicester |
| 25 Dec 00 | r00 | Aston VillaAston Villa | 0 - 1 | Manchester UnitedManchester Un |
| 25 Dec 00 | r00 | BradfordBradford | 1 - 4 | SunderlandSunderland |
| 25 Dec 00 | r00 | EvertonEverton | 1 - 2 | CoventryCoventry |
| 25 Dec 00 | r00 | IpswichIpswich | 2 - 2 | ChelseaChelsea |
| 25 Dec 00 | r00 | Manchester CityManchester Ci | 0 - 0 | DerbyDerby |
| 25 Dec 00 | r00 | MiddlesbroughMiddlesbrough | 1 - 0 | LiverpoolLiverpool |
| 25 Dec 00 | r00 | NewcastleNewcastle | 2 - 1 | LeedsLeeds |
| 25 Dec 00 | r00 | West HamWest Ham | 5 - 0 | CharltonCharlton |
| 26 Dec 00 | r00 | SouthamptonSouthampton | 2 - 0 | TottenhamTottenham |
| 29 Dec 00 | r00 | ArsenalArsenal | 2 - 2 | SunderlandSunderland |
| 29 Dec 00 | r00 | IpswichIpswich | 3 - 0 | TottenhamTottenham |
| 29 Dec 00 | r00 | Manchester CityManchester Ci | 1 - 4 | CharltonCharlton |
| 29 Dec 00 | r00 | MiddlesbroughMiddlesbrough | 1 - 1 | CoventryCoventry |
| 29 Dec 00 | r00 | NewcastleNewcastle | 1 - 1 | Manchester UnitedManchester Un |
| 29 Dec 00 | r00 | SouthamptonSouthampton | 1 - 0 | DerbyDerby |
| 31 Dec 00 | r00 | CharltonCharlton | 1 - 0 | ArsenalArsenal |
| 31 Dec 00 | r00 | ChelseaChelsea | 1 - 0 | Aston VillaAston Villa |
| 31 Dec 00 | r00 | CoventryCoventry | 1 - 1 | Manchester CityManchester Ci |
| 31 Dec 00 | r00 | DerbyDerby | 1 - 0 | EvertonEverton |
| 31 Dec 00 | r00 | LeedsLeeds | 1 - 1 | MiddlesbroughMiddlesbrough |
| 31 Dec 00 | r00 | LeicesterLeicester | 1 - 2 | BradfordBradford |
| 31 Dec 00 | r00 | LiverpoolLiverpool | 2 - 1 | SouthamptonSouthampton |
| 31 Dec 00 | r00 | Manchester UnitedManchester Un | 3 - 1 | West HamWest Ham |
| 31 Dec 00 | r00 | SunderlandSunderland | 4 - 1 | IpswichIpswich |
| 01 Jan 01 | r00 | TottenhamTottenham | 4 - 2 | NewcastleNewcastle |
| 12 Jan 01 | r00 | ArsenalArsenal | 1 - 1 | ChelseaChelsea |
| 12 Jan 01 | r00 | Aston VillaAston Villa | 0 - 3 | LiverpoolLiverpool |
| 12 Jan 01 | r00 | BradfordBradford | 0 - 3 | Manchester UnitedManchester Un |
| 12 Jan 01 | r00 | EvertonEverton | 0 - 0 | TottenhamTottenham |
| 12 Jan 01 | r00 | Manchester CityManchester Ci | 0 - 4 | LeedsLeeds |
| 12 Jan 01 | r00 | MiddlesbroughMiddlesbrough | 4 - 0 | DerbyDerby |
| 12 Jan 01 | r00 | NewcastleNewcastle | 3 - 1 | CoventryCoventry |
| 12 Jan 01 | r00 | SouthamptonSouthampton | 0 - 0 | CharltonCharlton |
| 12 Jan 01 | r00 | West HamWest Ham | 0 - 2 | SunderlandSunderland |
| 13 Jan 01 | r00 | IpswichIpswich | 2 - 0 | LeicesterLeicester |
| 19 Jan 01 | r00 | ChelseaChelsea | 4 - 1 | IpswichIpswich |
| 19 Jan 01 | r00 | CoventryCoventry | 1 - 3 | EvertonEverton |
| 19 Jan 01 | r00 | DerbyDerby | 1 - 1 | Manchester CityManchester Ci |
| 19 Jan 01 | r00 | LeedsLeeds | 1 - 3 | NewcastleNewcastle |
| 19 Jan 01 | r00 | LeicesterLeicester | 0 - 0 | ArsenalArsenal |
| 19 Jan 01 | r00 | LiverpoolLiverpool | 0 - 0 | MiddlesbroughMiddlesbrough |
| 19 Jan 01 | r00 | Manchester UnitedManchester Un | 2 - 0 | Aston VillaAston Villa |
| 19 Jan 01 | r00 | TottenhamTottenham | 0 - 0 | SouthamptonSouthampton |
| 20 Jan 01 | r00 | SunderlandSunderland | 0 - 0 | BradfordBradford |
| 21 Jan 01 | r00 | CharltonCharlton | 1 - 1 | West HamWest Ham |
| 23 Jan 01 | r00 | Aston VillaAston Villa | 1 - 2 | LeedsLeeds |
| 29 Jan 01 | r00 | ArsenalArsenal | 2 - 0 | BradfordBradford |
| 29 Jan 01 | r00 | CharltonCharlton | 2 - 1 | DerbyDerby |
| 30 Jan 01 | r00 | ChelseaChelsea | 3 - 1 | NewcastleNewcastle |
| 30 Jan 01 | r00 | EvertonEverton | 2 - 2 | MiddlesbroughMiddlesbrough |
| 30 Jan 01 | r00 | LeedsLeeds | 1 - 0 | CoventryCoventry |
| 30 Jan 01 | r00 | Manchester CityManchester Ci | 1 - 1 | LiverpoolLiverpool |
| 30 Jan 01 | r00 | SouthamptonSouthampton | 1 - 0 | LeicesterLeicester |
| 30 Jan 01 | r00 | SunderlandSunderland | 0 - 1 | Manchester UnitedManchester Un |
| 30 Jan 01 | r00 | West HamWest Ham | 0 - 0 | TottenhamTottenham |
| 02 Feb 01 | r00 | BradfordBradford | 0 - 3 | Aston VillaAston Villa |
| 02 Feb 01 | r00 | CoventryCoventry | 0 - 1 | ArsenalArsenal |
| 02 Feb 01 | r00 | DerbyDerby | 1 - 0 | SunderlandSunderland |
| 02 Feb 01 | r00 | IpswichIpswich | 1 - 2 | LeedsLeeds |
| 02 Feb 01 | r00 | LeicesterLeicester | 2 - 1 | ChelseaChelsea |
| 02 Feb 01 | r00 | LiverpoolLiverpool | 3 - 0 | West HamWest Ham |
| 02 Feb 01 | r00 | Manchester UnitedManchester Un | 1 - 0 | EvertonEverton |
| 02 Feb 01 | r00 | MiddlesbroughMiddlesbrough | 1 - 1 | Manchester CityManchester Ci |
| 02 Feb 01 | r00 | TottenhamTottenham | 0 - 0 | CharltonCharlton |
| 06 Feb 01 | r00 | EvertonEverton | 2 - 2 | LeedsLeeds |
| 09 Feb 01 | r00 | ArsenalArsenal | 1 - 0 | IpswichIpswich |
| 09 Feb 01 | r00 | Aston VillaAston Villa | 1 - 1 | MiddlesbroughMiddlesbrough |
| 09 Feb 01 | r00 | ChelseaChelsea | 1 - 1 | Manchester UnitedManchester Un |
| 09 Feb 01 | r00 | EvertonEverton | 2 - 1 | LeicesterLeicester |
| 09 Feb 01 | r00 | LeedsLeeds | 0 - 0 | DerbyDerby |
| 09 Feb 01 | r00 | Manchester CityManchester Ci | 0 - 1 | TottenhamTottenham |
| 09 Feb 01 | r00 | SouthamptonSouthampton | 2 - 0 | BradfordBradford |
| 09 Feb 01 | r00 | SunderlandSunderland | 1 - 1 | LiverpoolLiverpool |
| 10 Feb 01 | r00 | CharltonCharlton | 2 - 0 | NewcastleNewcastle |
| 11 Feb 01 | r00 | West HamWest Ham | 1 - 1 | CoventryCoventry |
| 23 Feb 01 | r00 | BradfordBradford | 1 - 2 | West HamWest Ham |
| 23 Feb 01 | r00 | CoventryCoventry | 2 - 2 | CharltonCharlton |
| 23 Feb 01 | r00 | DerbyDerby | 1 - 0 | Aston VillaAston Villa |
| 23 Feb 01 | r00 | IpswichIpswich | 2 - 0 | EvertonEverton |
| 23 Feb 01 | r00 | LeicesterLeicester | 2 - 0 | SunderlandSunderland |
| 23 Feb 01 | r00 | MiddlesbroughMiddlesbrough | 0 - 1 | SouthamptonSouthampton |
| 23 Feb 01 | r00 | NewcastleNewcastle | 0 - 1 | Manchester CityManchester Ci |
| 23 Feb 01 | r00 | TottenhamTottenham | 1 - 2 | LeedsLeeds |
| 24 Feb 01 | r00 | Manchester UnitedManchester Un | 6 - 1 | ArsenalArsenal |
| 02 Mar 01 | r00 | ArsenalArsenal | 3 - 0 | West HamWest Ham |
| 02 Mar 01 | r00 | CoventryCoventry | 0 - 0 | ChelseaChelsea |
| 02 Mar 01 | r00 | DerbyDerby | 2 - 1 | TottenhamTottenham |
| 02 Mar 01 | r00 | EvertonEverton | 1 - 1 | NewcastleNewcastle |
| 02 Mar 01 | r00 | LeedsLeeds | 1 - 1 | Manchester UnitedManchester Un |
| 02 Mar 01 | r00 | LeicesterLeicester | 2 - 0 | LiverpoolLiverpool |
| 02 Mar 01 | r00 | Manchester CityManchester Ci | 0 - 1 | SouthamptonSouthampton |
| 02 Mar 01 | r00 | MiddlesbroughMiddlesbrough | 0 - 0 | CharltonCharlton |
| 03 Mar 01 | r00 | IpswichIpswich | 3 - 1 | BradfordBradford |
| 04 Mar 01 | r00 | SunderlandSunderland | 1 - 1 | Aston VillaAston Villa |
| 06 Mar 01 | r00 | West HamWest Ham | 0 - 2 | ChelseaChelsea |
| 09 Mar 01 | r00 | Aston VillaAston Villa | 2 - 1 | IpswichIpswich |
| 16 Mar 01 | r00 | BradfordBradford | 2 - 2 | Manchester CityManchester Ci |
| 16 Mar 01 | r00 | CharltonCharlton | 1 - 2 | LeedsLeeds |
| 16 Mar 01 | r00 | ChelseaChelsea | 2 - 4 | SunderlandSunderland |
| 16 Mar 01 | r00 | Manchester UnitedManchester Un | 2 - 0 | LeicesterLeicester |
| 16 Mar 01 | r00 | NewcastleNewcastle | 1 - 2 | MiddlesbroughMiddlesbrough |
| 16 Mar 01 | r00 | SouthamptonSouthampton | 1 - 0 | EvertonEverton |
| 16 Mar 01 | r00 | TottenhamTottenham | 3 - 0 | CoventryCoventry |
| 16 Mar 01 | r00 | West HamWest Ham | 0 - 1 | IpswichIpswich |
| 17 Mar 01 | r00 | Aston VillaAston Villa | 0 - 0 | ArsenalArsenal |
| 17 Mar 01 | r00 | LiverpoolLiverpool | 1 - 1 | DerbyDerby |
| 30 Mar 01 | r00 | ArsenalArsenal | 2 - 0 | TottenhamTottenham |
| 30 Mar 01 | r00 | BradfordBradford | 2 - 2 | NewcastleNewcastle |
| 30 Mar 01 | r00 | ChelseaChelsea | 2 - 1 | MiddlesbroughMiddlesbrough |
| 30 Mar 01 | r00 | CoventryCoventry | 2 - 0 | DerbyDerby |
| 30 Mar 01 | r00 | LiverpoolLiverpool | 2 - 0 | Manchester UnitedManchester Un |
| 30 Mar 01 | r00 | Manchester CityManchester Ci | 1 - 3 | Aston VillaAston Villa |
| 30 Mar 01 | r00 | SunderlandSunderland | 0 - 2 | LeedsLeeds |
| 30 Mar 01 | r00 | West HamWest Ham | 0 - 2 | EvertonEverton |
| 31 Mar 01 | r00 | CharltonCharlton | 2 - 0 | LeicesterLeicester |
| 01 Apr 01 | r00 | SouthamptonSouthampton | 0 - 3 | IpswichIpswich |
| 03 Apr 01 | r00 | Aston VillaAston Villa | 2 - 1 | LeicesterLeicester |
| 06 Apr 01 | r00 | Aston VillaAston Villa | 2 - 2 | West HamWest Ham |
| 06 Apr 01 | r00 | DerbyDerby | 0 - 4 | ChelseaChelsea |
| 06 Apr 01 | r00 | LeedsLeeds | 2 - 0 | SouthamptonSouthampton |
| 06 Apr 01 | r00 | LeicesterLeicester | 1 - 3 | CoventryCoventry |
| 07 Apr 01 | r00 | EvertonEverton | 3 - 1 | Manchester CityManchester Ci |
| 08 Apr 01 | r00 | MiddlesbroughMiddlesbrough | 0 - 0 | SunderlandSunderland |
| 09 Apr 01 | r00 | IpswichIpswich | 1 - 1 | LiverpoolLiverpool |
| 09 Apr 01 | r00 | Manchester UnitedManchester Un | 2 - 1 | CharltonCharlton |
| 09 Apr 01 | r00 | TottenhamTottenham | 2 - 1 | BradfordBradford |
| 10 Apr 01 | r00 | Manchester CityManchester Ci | 0 - 4 | ArsenalArsenal |
| 12 Apr 01 | r00 | BradfordBradford | 2 - 0 | CharltonCharlton |
| 12 Apr 01 | r00 | LiverpoolLiverpool | 1 - 2 | LeedsLeeds |
| 13 Apr 01 | r00 | ArsenalArsenal | 0 - 3 | MiddlesbroughMiddlesbrough |
| 13 Apr 01 | r00 | Aston VillaAston Villa | 2 - 1 | EvertonEverton |
| 13 Apr 01 | r00 | ChelseaChelsea | 1 - 0 | SouthamptonSouthampton |
| 13 Apr 01 | r00 | IpswichIpswich | 1 - 0 | NewcastleNewcastle |
| 13 Apr 01 | r00 | LeicesterLeicester | 1 - 2 | Manchester CityManchester Ci |
| 13 Apr 01 | r00 | Manchester UnitedManchester Un | 4 - 2 | CoventryCoventry |
| 13 Apr 01 | r00 | SunderlandSunderland | 2 - 3 | TottenhamTottenham |
| 13 Apr 01 | r00 | West HamWest Ham | 3 - 1 | DerbyDerby |
| 15 Apr 01 | r00 | CoventryCoventry | 1 - 0 | SunderlandSunderland |
| 15 Apr 01 | r00 | DerbyDerby | 2 - 0 | LeicesterLeicester |
| 15 Apr 01 | r00 | EvertonEverton | 2 - 3 | LiverpoolLiverpool |
| 15 Apr 01 | r00 | MiddlesbroughMiddlesbrough | 1 - 2 | IpswichIpswich |
| 15 Apr 01 | r00 | NewcastleNewcastle | 2 - 1 | West HamWest Ham |
| 16 Apr 01 | r00 | CharltonCharlton | 3 - 3 | Aston VillaAston Villa |
| 16 Apr 01 | r00 | TottenhamTottenham | 0 - 3 | ChelseaChelsea |
| 20 Apr 01 | r00 | ArsenalArsenal | 4 - 1 | EvertonEverton |
| 20 Apr 01 | r00 | Aston VillaAston Villa | 0 - 0 | SouthamptonSouthampton |
| 20 Apr 01 | r00 | BradfordBradford | 2 - 0 | DerbyDerby |
| 20 Apr 01 | r00 | ChelseaChelsea | 0 - 1 | CharltonCharlton |
| 20 Apr 01 | r00 | IpswichIpswich | 2 - 0 | CoventryCoventry |
| 20 Apr 01 | r00 | LeicesterLeicester | 0 - 3 | MiddlesbroughMiddlesbrough |
| 20 Apr 01 | r00  | Manchester UnitedManchester Un | 1 - 1 | Manchester CityManchester Ci |
| 20 Apr 01 | r00 | SunderlandSunderland | 1 - 1 | NewcastleNewcastle |
| 20 Apr 01 | r00 | West HamWest Ham | 0 - 2 | LeedsLeeds |
| 21 Apr 01 | r00 | LiverpoolLiverpool | 3 - 1 | TottenhamTottenham |
| 27 Apr 01 | r00 | CoventryCoventry | 0 - 2 | LiverpoolLiverpool |
| 27 Apr 01 | r00 | DerbyDerby | 1 - 2 | ArsenalArsenal |
| 27 Apr 01 | r00 | EvertonEverton | 2 - 1 | BradfordBradford |
| 27 Apr 01 | r00 | LeedsLeeds | 2 - 0 | ChelseaChelsea |
| 27 Apr 01 | r00 | Manchester CityManchester Ci | 1 - 0 | West HamWest Ham |
| 27 Apr 01 | r00 | MiddlesbroughMiddlesbrough | 0 - 2 | Manchester UnitedManchester Un |
| 27 Apr 01 | r00 | NewcastleNewcastle | 1 - 0 | LeicesterLeicester |
| 27 Apr 01 | r00 | SouthamptonSouthampton | 0 - 1 | SunderlandSunderland |
| 27 Apr 01 | r00 | TottenhamTottenham | 0 - 0 | Aston VillaAston Villa |
| 29 Apr 01 | r00 | CharltonCharlton | 2 - 1 | IpswichIpswich |
| 30 Apr 01 | r00 | BradfordBradford | 0 - 2 | LiverpoolLiverpool |
| 30 Apr 01 | r00 | NewcastleNewcastle | 1 - 1 | SouthamptonSouthampton |
| 04 May 01 | r00 | ArsenalArsenal | 2 - 1 | LeedsLeeds |
| 04 May 01 | r00 | Aston VillaAston Villa | 3 - 2 | CoventryCoventry |
| 04 May 01 | r00 | BradfordBradford | 1 - 1 | MiddlesbroughMiddlesbrough |
| 04 May 01 | r00 | ChelseaChelsea | 2 - 1 | EvertonEverton |
| 04 May 01 | r00 | LeicesterLeicester | 4 - 2 | TottenhamTottenham |
| 04 May 01 | r00 | LiverpoolLiverpool | 3 - 0 | NewcastleNewcastle |
| 04 May 01 | r00 | Manchester UnitedManchester Un | 0 - 1 | DerbyDerby |
| 04 May 01 | r00 | SunderlandSunderland | 3 - 2 | CharltonCharlton |
| 04 May 01 | r00 | West HamWest Ham | 3 - 0 | SouthamptonSouthampton |
| 06 May 01 | r00 | IpswichIpswich | 2 - 1 | Manchester CityManchester Ci |
| 07 May 01 | r00 | LiverpoolLiverpool | 2 - 2 | ChelseaChelsea |
| 12 May 01 | r00 | LeedsLeeds | 6 - 1 | BradfordBradford |
| 12 May 01 | r00 | SouthamptonSouthampton | 2 - 1 | Manchester UnitedManchester Un |
| 14 May 01 | r00 | NewcastleNewcastle | 0 - 0 | ArsenalArsenal |
| 18 May 01 | r00 | CharltonCharlton | 0 - 4 | LiverpoolLiverpool |
| 18 May 01 | r00 | CoventryCoventry | 0 - 0 | BradfordBradford |
| 18 May 01 | r00 | DerbyDerby | 1 - 1 | IpswichIpswich |
| 18 May 01 | r00 | EvertonEverton | 2 - 2 | SunderlandSunderland |
| 18 May 01 | r00 | LeedsLeeds | 3 - 1 | LeicesterLeicester |
| 18 May 01 | r00 | Manchester CityManchester Ci | 1 - 2 | ChelseaChelsea |
| 18 May 01 | r00 | MiddlesbroughMiddlesbrough | 2 - 1 | West HamWest Ham |
| 18 May 01 | r00 | NewcastleNewcastle | 3 - 0 | Aston VillaAston Villa |
| 18 May 01 | r00 | SouthamptonSouthampton | 3 - 2 | ArsenalArsenal |
| 18 May 01 | r00 | TottenhamTottenham | 3 - 1 | Manchester UnitedManchester Un |
Team 2000-2001 Schedules
Arsenal
Aston Villa
Bournemouth
Brentford
Brighton and Hove Albion
Chelsea
Coventry City
Crystal Palace
Everton
Fulham
Hull City
Ipswich Town
Leeds United
Liverpool
Manchester City
Manchester United
Newcastle United
Nottingham Forest
Sunderland
Tottenham Hotspur
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