| 24 Sep 21 | r00   | Heroes Den BoschHeroes Den Bo | 72 - 64 | ZZ LeidenZZ Leiden |
| 26 Sep 21 | r00 | Landstede HammersLandstede Ham | 49 - 65 | Heroes Den BoschHeroes Den Bo |
| 29 Sep 21 | r00 | Aris LeeuwardenAris Leeuward | 83 - 90 | Heroes Den BoschHeroes Den Bo |
| 02 Oct 21 | r00 | Apollo AmsterdamApollo Amster | 57 - 103 | Heroes Den BoschHeroes Den Bo |
| 07 Oct 21 | r00 | Den Helder SunsDen Helder Su | 75 - 94 | Heroes Den BoschHeroes Den Bo |
| 10 Oct 21 | r00 | Yoast UnitedYoast United | 71 - 84 | Heroes Den BoschHeroes Den Bo |
| 15 Oct 21 | r00 | Heroes Den BoschHeroes Den Bo | 102 - 70 | The Hague RoyalsThe Hague Roy |
| 23 Oct 21 | r00 | DonarDonar | 62 - 68 | Heroes Den BoschHeroes Den Bo |
| 31 Oct 21 | r00 | Heroes Den BoschHeroes Den Bo | 93 - 78 | Aris LeeuwardenAris Leeuward |
| 07 Nov 21 | r00 | Heroes Den BoschHeroes Den Bo | 90 - 61 | Den Helder SunsDen Helder Su |
| 05 Dec 21 | r00 | Heroes Den BoschHeroes Den Bo | 90 - 63 | Apollo AmsterdamApollo Amster |
| 09 Dec 21 | r00 | Heroes Den BoschHeroes Den Bo | 90 - 85 | Yoast UnitedYoast United |
| 14 Dec 21 | r00 | Heroes Den BoschHeroes Den Bo | 97 - 56 | BAL WeertBAL Weert |
| 22 Dec 21 | r00 | The Hague RoyalsThe Hague Roy | 54 - 97 | Heroes Den BoschHeroes Den Bo |
| 09 Jan 22 | r00 | ZZ LeidenZZ Leiden | 85 - 70 | Heroes Den BoschHeroes Den Bo |
| 13 Jan 22 | r00 | BAL WeertBAL Weert | 77 - 87 | Heroes Den BoschHeroes Den Bo |
| 22 Jan 22 | r00 | Feyenoord BasketballFeyenoord Bas | 82 - 72 | Heroes Den BoschHeroes Den Bo |
| 29 Jan 22 | r00 | Heroes Den BoschHeroes Den Bo | 100 - 87 | DonarDonar |
| 06 Feb 22 | r00 | Heroes Den BoschHeroes Den Bo | 87 - 70 | Landstede HammersLandstede Ham |
| 19 Feb 22 | r00 | Heroes Den BoschHeroes Den Bo | 113 - 70 | Feyenoord BasketballFeyenoord Bas |
| 05 Mar 22 | r00 | Belfius Mons-HainautBelfius Mons- | 88 - 85 | Heroes Den BoschHeroes Den Bo |
| 17 Mar 22 | r00 | Heroes Den BoschHeroes Den Bo | 95 - 81 | Antwerp GiantsAntwerp Giant |
| 23 Mar 22 | r00 | Leuven BearsLeuven Bears | 84 - 65 | Heroes Den BoschHeroes Den Bo |
| 26 Mar 22 | r00 | Kangoeroes MechelenKangoeroes Me | 84 - 66 | Heroes Den BoschHeroes Den Bo |
| 01 Apr 22 | r00 | Heroes Den BoschHeroes Den Bo | 75 - 66 | BC OostendeBC Oostende |
| 08 Apr 22 | r00 | BC OostendeBC Oostende | 100 - 69 | Heroes Den BoschHeroes Den Bo |
| 18 Apr 22 | r00 | Heroes Den BoschHeroes Den Bo | 76 - 74 | Leuven BearsLeuven Bears |
| 20 Apr 22 | r00 | Heroes Den BoschHeroes Den Bo | 75 - 76 | Kangoeroes MechelenKangoeroes Me |
| 22 Apr 22 | r00 | Antwerp GiantsAntwerp Giant | 69 - 53 | Heroes Den BoschHeroes Den Bo |
| 29 Apr 22 | r00 | Heroes Den BoschHeroes Den Bo | 83 - 80 | Belfius Mons-HainautBelfius Mons- |
| 05 Jun 22 | r00 | DonarDonar | 68 - 68 | Heroes Den BoschHeroes Den Bo |
| 07 Jun 22 | r00 | Heroes Den BoschHeroes Den Bo | 100 - 101 | DonarDonar |
Team 2021-2022 Schedules
Antwerp Giants
BAL Weert
BC Oostende
Belfius Mons-Hainaut
Brussels Basketball
Den Helder Suns
Donar
Heroes Den Bosch
Kangoeroes Mechelen
Kortrijk Spurs
Landstede Hammers
Leuven Bears
Limburg United
LWD Basket
Okapi Aalst
Rotterdam City Basketball
Spirou Charleroi
ZZ Leiden
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