| 31 Oct 21 | r01        | Etoile de lEstEtoile de lEs | 0 - 3 | Rwanda PoliceRwanda Police |
| |
| 03 Nov 21 | r02        | Rwanda PoliceRwanda Police | 0 - 2 | EspoirEspoir |
| |
| 19 Nov 21 | r03        | Kiyovu SportsKiyovu Sports | 1 - 1 | Rwanda PoliceRwanda Police |
| |
| 22 Nov 21 | r04        | Rwanda PoliceRwanda Police | 0 - 0 | GorillaGorilla |
| |
| 27 Nov 21 | r05        | A.S. KigaliA.S. Kigali | 2 - 2 | Rwanda PoliceRwanda Police |
| |
| 01 Dec 21 | r06        | Rwanda PoliceRwanda Police | 1 - 0 | MarinesMarines |
| |
| 04 Dec 21 | r07        | Rwanda PoliceRwanda Police | 0 - 0 | GicumbiGicumbi |
| |
| 10 Dec 21 | r08        | MusanzeMusanze | 1 - 2 | Rwanda PoliceRwanda Police |
| |
| 19 Dec 21 | r09        | Rwanda PoliceRwanda Police | 3 - 0 | EtincellesEtincelles |
| |
| 22 Dec 21 | r10        | Rayon SportsRayon Sports | 1 - 0 | Rwanda PoliceRwanda Police |
| |
| 29 Dec 21 | r11        | Rwanda PoliceRwanda Police | 3 - 2 | Gasogi UnitedGasogi United |
| |
| 17 Jan 22 | r12        | MukuraMukura | 0 - 1 | Rwanda PoliceRwanda Police |
| |
| 20 Jan 22 | r13        | Rwanda PoliceRwanda Police | 1 - 1 | RutsiroRutsiro |
| |
| 24 Jan 22 | r14        | Rwanda PoliceRwanda Police | 1 - 2 | BugeseraBugesera |
| |
| 28 Jan 22 | r15        | APRAPR | 2 - 1 | Rwanda PoliceRwanda Police |
| |
| 13 Feb 22 | r16        | Rwanda PoliceRwanda Police | 6 - 0 | Etoile de lEstEtoile de lEs |
| |
| 17 Feb 22 | r17        | EspoirEspoir | 2 - 0 | Rwanda PoliceRwanda Police |
| |
| 20 Feb 22 | r18        | Rwanda PoliceRwanda Police | 0 - 1 | Kiyovu SportsKiyovu Sports |
| |
| 25 Feb 22 | r19        | GorillaGorilla | 1 - 2 | Rwanda PoliceRwanda Police |
| |
| 06 Mar 22 | r20        | Rwanda PoliceRwanda Police | 1 - 1 | A.S. KigaliA.S. Kigali |
| |
| 13 Mar 22 | r21        | MarinesMarines | 1 - 1 | Rwanda PoliceRwanda Police |
| |
| 20 Mar 22 | r22        | GicumbiGicumbi | 1 - 1 | Rwanda PoliceRwanda Police |
| |
| 15 Apr 22 | r23        | Rwanda PoliceRwanda Police | 1 - 0 | MusanzeMusanze |
| |
| 23 Apr 22 | r24        | EtincellesEtincelles | 1 - 0 | Rwanda PoliceRwanda Police |
| |
| 30 Apr 22 | r25        | Rwanda PoliceRwanda Police | 1 - 1 | Rayon SportsRayon Sports |
| |
| 08 May 22 | r26        | Gasogi UnitedGasogi United | 3 - 0 | Rwanda PoliceRwanda Police |
| |
| 15 May 22 | r27        | Rwanda PoliceRwanda Police | 1 - 1 | MukuraMukura |
| |
| 22 May 22 | r28        | RutsiroRutsiro | 2 - 3 | Rwanda PoliceRwanda Police |
| |
| 13 Jun 22 | r29        | BugeseraBugesera | 2 - 0 | Rwanda PoliceRwanda Police |
| |
| 16 Jun 22 | r30        | Rwanda PoliceRwanda Police | 0 - 1 | APRAPR |