| 06 Nov 21 | r01  | Dynamique DjougouDynamique Djo | 0 - 0 | DamissaDamissa |
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| 13 Nov 21 | r02 | Béké BembèrèkèBéké Bembèrèk | 2 - 1 | DamissaDamissa |
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| 17 Nov 21 | r03 | DamissaDamissa | 0 - 0 | PanthèresPanthères |
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| 20 Nov 21 | r04 | Dynamo UnacobDynamo Unacob | 3 - 1 | DamissaDamissa |
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| 27 Nov 21 | r05 | DamissaDamissa | 1 - 2 | Cavaliers FC de NikkiCavaliers FC |
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| 01 Dec 21 | r06 | DamissaDamissa | 0 - 0 | Réal Sports de Parakou FCRéal Sports d |
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| 05 Dec 21 | r07 | TukunninTukunnin | 1 - 0 | DamissaDamissa |
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| 18 Dec 21 | r09 | DamissaDamissa | 1 - 0 | Les Buffles du BorgouLes Buffles d |
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| 22 Dec 21 | r10 | DamissaDamissa | 1 - 0 | Dynamique DjougouDynamique Djo |
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| 29 Dec 21 | r11 | DamissaDamissa | 1 - 0 | Béké BembèrèkèBéké Bembèrèk |
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| 05 Jan 22 | r12 | PanthèresPanthères | 0 - 0 | DamissaDamissa |
| |
| 08 Jan 22 | r13 | DamissaDamissa | 1 - 0 | Dynamo UnacobDynamo Unacob |
| |
| 15 Jan 22 | r14 | Cavaliers FC de NikkiCavaliers FC | 0 - 1 | DamissaDamissa |
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| 20 Jan 22 | r15 | Réal Sports de Parakou FCRéal Sports d | 1 - 2 | DamissaDamissa |
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| 23 Jan 22 | r16 | DamissaDamissa | 2 - 1 | TukunninTukunnin |
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| 30 Jan 22 | r18 | Les Buffles du BorgouLes Buffles d | 0 - 2 | DamissaDamissa |
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| 13 Mar 22 | r01 | DamissaDamissa | 1 - 2 | EnergieEnergie |
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| 18 Mar 22 | r02 | Union Sportive du Borgou Union Sportiv | 0 - 0 | DamissaDamissa |
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| 27 Mar 22 | r03 | DamissaDamissa | 1 - 1 | Dynamo UnacobDynamo Unacob |
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| 30 Mar 22 | r04 | DamissaDamissa | 0 - 0 | TonnerreTonnerre |
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| 03 Apr 22 | r05 | HodioHodio | 0 - 0 | DamissaDamissa |
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| 10 Apr 22 | r06 | DamissaDamissa | 1 - 2 | TukunninTukunnin |
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| 16 Apr 22 | r07 | SoleilSoleil | 2 - 2 | DamissaDamissa |
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| 20 Apr 22 | r08 | DamissaDamissa | 1 - 0 | Réal Sports de Parakou FCRéal Sports d |
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| 25 Apr 22 | r09 | Dynamique DjougouDynamique Djo | 0 - 2 | DamissaDamissa |
| |
| 30 Apr 22 | r10 | EnergieEnergie | 0 - 1 | DamissaDamissa |
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| 07 May 22 | r11 | DamissaDamissa | 0 - 0 | Union Sportive du Borgou Union Sportiv |
| |
| 13 May 22 | r12 | Dynamo UnacobDynamo Unacob | 1 - 1 | DamissaDamissa |
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| 18 May 22 | r13 | TonnerreTonnerre | 0 - 1 | DamissaDamissa |
| |
| 21 May 22 | r14 | DamissaDamissa | 1 - 1 | HodioHodio |
| |
| 28 May 22 | r15 | TukunninTukunnin | 0 - 3 | DamissaDamissa |
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| 04 Jun 22 | r16 | DamissaDamissa | 1 - 0 | SoleilSoleil |
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| 09 Jun 22 | r17 | Réal Sports de Parakou FCRéal Sports d | 1 - 0 | DamissaDamissa |
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| 12 Jun 22 | r18 | DamissaDamissa | 0 - 1 | Dynamique DjougouDynamique Djo |
Team 2021-2022 Schedules
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ASVO
Ayema
Bani Gansè
Cavaliers de Nikki
Coton Sport Ouidah
Cotonou
Dadjè
Damissa
Dragons de l'Ouémé
Dynamo Abomey
Espoir Savalou
Hodio
Kraké
Les Buffles du Borgou
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