| 08 Jan 22 | r22        | Ashford UnitedAshford Unite | 2 - 2 | LancingLancing |
| 08 Jan 22 | r22        | Hastings UnitedHastings Unit | 4 - 0 | Faversham TownFaversham Tow |
| 08 Jan 22 | r22        | Three BridgesThree Bridges | 3 - 4 | VCD AthleticVCD Athletic |
| 08 Jan 22 | r22        | Whitstable TownWhitstable To | 2 - 2 | CorinthianCorinthian |
| 25 Jan 22 | r22        | Phoenix SportsPhoenix Sport | 1 - 2 | East Grinstead TownEast Grinstea |
| 25 Jan 22 | r22        | SittingbourneSittingbourne | 0 - 1 | Burgess Hill TownBurgess Hill |
| 01 Feb 22 | r22        | Cray Valley PMCray Valley P | 3 - 0 | Sevenoaks TownSevenoaks Tow |
| 08 Feb 22 | r22        | Chichester CityChichester Ci | 0 - 1 | Herne BayHerne Bay |
| 08 Feb 22 | r22        | Hythe TownHythe Town | 2 - 2 | WhitehawkWhitehawk |
| 15 Feb 22 | r22        | Haywards Heath TownHaywards Heat | 1 - 0 | RamsgateRamsgate |