| 29 Aug 21 | r01  | Blackburn Rovers LFCBlackburn Rov | 2 - 0 | Sheffield United WFCSheffield Uni |
| |
| 05 Sep 21 | r02 | Sheffield United WFCSheffield Uni | 3 - 1 | Durham WFCDurham WFC |
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| 12 Sep 21 | r03 | Coventry United LFCCoventry Unit | 0 - 3 | Sheffield United WFCSheffield Uni |
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| 26 Sep 21 | r04 | Sheffield United WFCSheffield Uni | 3 - 0 | Watford WomenWatford Women |
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| 03 Oct 21 | r05 | Crystal Palace FC WomenCrystal Palac | 0 - 0 | Sheffield United WFCSheffield Uni |
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| 09 Oct 21 | r06 | Sheffield United WFCSheffield Uni | 0 - 2 | Liverpool FC WomenLiverpool FC |
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| 31 Oct 21 | r07 | Bristol City WFCBristol City | 5 - 1 | Sheffield United WFCSheffield Uni |
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| 07 Nov 21 | r08 | Sheffield United WFCSheffield Uni | 0 - 0 | Charlton Athletic WFCCharlton Athl |
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| 14 Nov 21 | r09 | London City LionessesLondon City L | 1 - 0 | Sheffield United WFCSheffield Uni |
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| 21 Nov 21 | r10 | Sheffield United WFCSheffield Uni | 1 - 3 | Lewes FC WomenLewes FC Wome |
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| 19 Dec 21 | r11 | Sheffield United WFCSheffield Uni | P - P | Sunderland WomenSunderland Wo |
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| 09 Jan 22 | r12 | Charlton Athletic WFCCharlton Athl | 0 - 0 | Sheffield United WFCSheffield Uni |
| |
| 16 Jan 22 | r13 | Sheffield United WFCSheffield Uni | 3 - 1 | Coventry United LFCCoventry Unit |
| |
| 23 Jan 22 | r14 | Durham WFCDurham WFC | 1 - 1 | Sheffield United WFCSheffield Uni |
| |
| 06 Feb 22 | r15 | Sunderland WomenSunderland Wo | 2 - 2 | Sheffield United WFCSheffield Uni |
| |
| 13 Feb 22 | r16 | Sheffield United WFCSheffield Uni | 4 - 0 | Blackburn Rovers LFCBlackburn Rov |
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| 05 Mar 22 | r17 | Watford WomenWatford Women | - | Sheffield United WFCSheffield Uni |
| |
| 13 Mar 22 | r18 | Sheffield United WFCSheffield Uni | - | London City LionessesLondon City L |
| |
| 27 Mar 22 | r19 | Sheffield United WFCSheffield Uni | - | Bristol City WFCBristol City |
| |
| 03 Apr 22 | r20 | Lewes FC WomenLewes FC Wome | 0 - 2 | Sheffield United WFCSheffield Uni |
| |
| 24 Apr 22 | r21 | Liverpool FC WomenLiverpool FC | 6 - 1 | Sheffield United WFCSheffield Uni |
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| 01 May 22 | r22 | Sheffield United WFCSheffield Uni | 2 - 2 | Crystal Palace FC WomenCrystal Palac |
| |
| 21 Aug 22 | r01 | Blackburn Rovers LFCBlackburn Rov | 1 - 0 | Sheffield United WFCSheffield Uni |
| |
| 27 Aug 22 | r02 | Sheffield United WFCSheffield Uni | 2 - 0 | Durham WFCDurham WFC |
| |
| 18 Sep 22 | r04 | Sheffield United WFCSheffield Uni | 8 - 0 | Coventry United LFCCoventry Unit |
| |
| 25 Sep 22 | r05 | Lewes FC WomenLewes FC Wome | 2 - 2 | Sheffield United WFCSheffield Uni |
| |
| 16 Oct 22 | r06 | Sheffield United WFCSheffield Uni | 1 - 3 | Bristol City WFCBristol City |
| |
| 23 Oct 22 | r07 | Sheffield United WFCSheffield Uni | 0 - 1 | Southampton F.C. WomenSouthampton F |
| |
| 30 Oct 22 | r08 | Birmingham City WFCBirmingham Ci | 2 - 1 | Sheffield United WFCSheffield Uni |
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| 20 Nov 22 | r10 | Sheffield United WFCSheffield Uni | 0 - 2 | London City LionessesLondon City L |
| |
| 04 Dec 22 | r11 | Charlton Athletic WFCCharlton Athl | 1 - 0 | Sheffield United WFCSheffield Uni |
| |
| 15 Jan 23 | r12 | Sheffield United WFCSheffield Uni | - | Birmingham City WFCBirmingham Ci |
| |
| 22 Jan 23 | r13 | Sheffield United WFCSheffield Uni | - | Blackburn Rovers LFCBlackburn Rov |
| |
| 05 Feb 23 | r14 | Durham WFCDurham WFC | - | Sheffield United WFCSheffield Uni |
| |
| 12 Feb 23 | r15 | Sheffield United WFCSheffield Uni | - | Charlton Athletic WFCCharlton Athl |
| |
| 26 Feb 23 | r09 | Crystal Palace FC WomenCrystal Palac | - | Sheffield United WFCSheffield Uni |
| |
| 05 Mar 23 | r16 | London City LionessesLondon City L | - | Sheffield United WFCSheffield Uni |
| |
| 12 Mar 23 | r17 | Sheffield United WFCSheffield Uni | - | Crystal Palace FC WomenCrystal Palac |
| |
| 19 Mar 23 | r03 | Sunderland WomenSunderland Wo | - | Sheffield United WFCSheffield Uni |
| |
| 26 Mar 23 | r18 | Sheffield United WFCSheffield Uni | - | Lewes FC WomenLewes FC Wome |
| |
| 02 Apr 23 | r19 | Bristol City WFCBristol City | - | Sheffield United WFCSheffield Uni |
| |
| 16 Apr 23 | r20 | Coventry United LFCCoventry Unit | - | Sheffield United WFCSheffield Uni |
| |
| 23 Apr 23 | r21 | Sheffield United WFCSheffield Uni | - | Sunderland WomenSunderland Wo |
| |
| 30 Apr 23 | r22 | Southampton F.C. WomenSouthampton F | - | Sheffield United WFCSheffield Uni |
Team 2022 Schedules
Birmingham City WFC
Bristol City WFC
Charlton Athletic WFC
Crystal Palace FC Women
Durham WFC
Ipswich Women
Newcastle Women
Nottingham Forest WFC
Portsmouth Women
Sheffield United WFC
Southampton F.C. Women
Sunderland Women
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