| 04 Sep 21 | r01        | MarrMarr | 33 - 7 | Glasgow HawksGlasgow Hawks |
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| 11 Sep 21 | r02        | Glasgow HawksGlasgow Hawks | 28 - 8 | Aberdeen GSFPAberdeen GSFP |
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| 18 Sep 21 | r03        | Jed-ForestJed-Forest | 18 - 21 | Glasgow HawksGlasgow Hawks |
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| 25 Sep 21 | r04        | Glasgow HawksGlasgow Hawks | 43 - 19 | MusselburghMusselburgh |
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| 02 Oct 21 | r05        | HawickHawick | 14 - 10 | Glasgow HawksGlasgow Hawks |
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| 09 Oct 21 | r06        | Glasgow HawksGlasgow Hawks | 13 - 14 | CurrieCurrie |
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| 16 Oct 21 | r07        | Glasgow Hutchesons AloysiGlasgow Hutch | 19 - 36 | Glasgow HawksGlasgow Hawks |
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| 23 Oct 21 | r08        | Glasgow HawksGlasgow Hawks | 40 - 26 | SelkirkSelkirk |
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| 30 Oct 21 | r09        | Edinburgh AcademicalsEdinburgh Aca | 36 - 34 | Glasgow HawksGlasgow Hawks |
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| 06 Nov 21 | r10        | Glasgow HawksGlasgow Hawks | 9 - 20 | MarrMarr |
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| 27 Nov 21 | r11        | Aberdeen GSFPAberdeen GSFP | 38 - 13 | Glasgow HawksGlasgow Hawks |
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| 04 Dec 21 | r12        | Glasgow HawksGlasgow Hawks | 17 - 10 | Jed-ForestJed-Forest |
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| 08 Jan 22 | r14        | Glasgow HawksGlasgow Hawks | 31 - 10 | HawickHawick |
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| 15 Jan 22 | r15        | CurrieCurrie | 32 - 0 | Glasgow HawksGlasgow Hawks |
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| 22 Jan 22 | r16        | Glasgow HawksGlasgow Hawks | 7 - 20 | Glasgow Hutchesons AloysiGlasgow Hutch |
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| 29 Jan 22 | r17        | SelkirkSelkirk | 10 - 20 | Glasgow HawksGlasgow Hawks |
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| 12 Feb 22 | r13        | MusselburghMusselburgh | 34 - 17 | Glasgow HawksGlasgow Hawks |
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| 19 Feb 22 | r18        | Glasgow HawksGlasgow Hawks | 25 - 34 | Edinburgh AcademicalsEdinburgh Aca |