| 26 Aug 21 | r01  | Aviron BayonnaisAviron Bayonn | 37 - 16 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 03 Sep 21 | r02 | SU Agen Lot-et-GaronneSU Agen Lot-e | 9 - 12 | BéziersBéziers |
| |
| 09 Sep 21 | r03 | FC GrenobleFC Grenoble | 17 - 13 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 17 Sep 21 | r04 | SU Agen Lot-et-GaronneSU Agen Lot-e | 24 - 28 | Bourg-en-BresseBourg-en-Bres |
| |
| 24 Sep 21 | r05 | Mont-de-MarsanMont-de-Marsa | 43 - 8 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 08 Oct 21 | r06 | SU Agen Lot-et-GaronneSU Agen Lot-e | 15 - 17 | NarbonneNarbonne |
| |
| 15 Oct 21 | r07 | VannesVannes | 46 - 3 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 22 Oct 21 | r08 | SU Agen Lot-et-GaronneSU Agen Lot-e | 25 - 21 | AurillacAurillac |
| |
| 29 Oct 21 | r09 | CarcassonneCarcassonne | 15 - 11 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 04 Nov 21 | r10 | SU Agen Lot-et-GaronneSU Agen Lot-e | 41 - 17 | US MontaubanUS Montauban |
| |
| 19 Nov 21 | r11 | RouenRouen | 27 - 23 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 26 Nov 21 | r12 | SU Agen Lot-et-GaronneSU Agen Lot-e | 14 - 19 | Oyonnax RugbyOyonnax Rugby |
| |
| 03 Dec 21 | r13 | SU Agen Lot-et-GaronneSU Agen Lot-e | 18 - 8 | ColomiersColomiers |
| |
| 10 Dec 21 | r14 | NeversNevers | 41 - 8 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 17 Dec 21 | r15 | SU Agen Lot-et-GaronneSU Agen Lot-e | 20 - 18 | ProvenceProvence |
| |
| 06 Jan 22 | r16 | SU Agen Lot-et-GaronneSU Agen Lot-e | 16 - 16 | Aviron BayonnaisAviron Bayonn |
| |
| 13 Jan 22 | r17 | NarbonneNarbonne | 24 - 26 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 28 Jan 22 | r19 | BéziersBéziers | 29 - 3 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 03 Feb 22 | r18 | SU Agen Lot-et-GaronneSU Agen Lot-e | 39 - 18 | VannesVannes |
| |
| 10 Feb 22 | r20 | SU Agen Lot-et-GaronneSU Agen Lot-e | 30 - 9 | FC GrenobleFC Grenoble |
| |
| 18 Feb 22 | r21 | Bourg-en-BresseBourg-en-Bres | 37 - 32 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 25 Feb 22 | r22 | SU Agen Lot-et-GaronneSU Agen Lot-e | 27 - 30 | Mont-de-MarsanMont-de-Marsa |
| |
| 04 Mar 22 | r23 | AurillacAurillac | 23 - 22 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 11 Mar 22 | r24 | SU Agen Lot-et-GaronneSU Agen Lot-e | 22 - 19 | CarcassonneCarcassonne |
| |
| 01 Apr 22 | r25 | US MontaubanUS Montauban | 21 - 15 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 08 Apr 22 | r26 | SU Agen Lot-et-GaronneSU Agen Lot-e | 31 - 10 | RouenRouen |
| |
| 15 Apr 22 | r27 | Oyonnax RugbyOyonnax Rugby | 54 - 35 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 22 Apr 22 | r28 | ProvenceProvence | 26 - 17 | SU Agen Lot-et-GaronneSU Agen Lot-e |
| |
| 06 May 22 | r29 | SU Agen Lot-et-GaronneSU Agen Lot-e | 25 - 22 | NeversNevers |
| |
| 12 May 22 | r30 | ColomiersColomiers | 21 - 16 | SU Agen Lot-et-GaronneSU Agen Lot-e |
Team 2021-2022 Schedules
Aurillac
Béziers
Biarritz Olympique
CA Brive
Carcassonne
Colomiers
FC Grenoble
Mont-de-Marsan
Nevers
Oyonnax Rugby
Provence
Soyaux Angoulême XV Charente
Stade Niçois
SU Agen Lot-et-Garonne
US Dax
Valence Romans Drôme Rugby
Vannes
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Poster
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