| 02 Oct 21 | r01  | KK RogaškaKK Rogaška | 68 - 53 | KK Triglav KranjKK Triglav Kr |
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| 08 Oct 21 | r02 | KK RogaškaKK Rogaška | 68 - 75 | KK PodčetrtekKK Podčetrtek |
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| 20 Oct 21 | r03 | KK KrkaKK Krka | 77 - 64 | KK RogaškaKK Rogaška |
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| 23 Oct 21 | r04 | KK RogaškaKK Rogaška | 78 - 79 | KD IlirijaKD Ilirija |
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| 01 Nov 21 | r05 | Helios SunsHelios Suns | 97 - 74 | KK RogaškaKK Rogaška |
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| 05 Nov 21 | r06 | KK RogaškaKK Rogaška | 87 - 90 | KD Hopsi PolzelaKD Hopsi Polz |
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| 13 Nov 21 | r07 | KK ŠenčurKK Šenčur | 92 - 62 | KK RogaškaKK Rogaška |
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| 20 Nov 21 | r08 | KK RogaškaKK Rogaška | 91 - 58 | KK Zlatorog LaškoKK Zlatorog L |
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| 04 Dec 21 | r09 | KK ŠentjurKK Šentjur | 90 - 88 | KK RogaškaKK Rogaška |
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| 07 Dec 21 | r10 | KK Triglav KranjKK Triglav Kr | 76 - 78 | KK RogaškaKK Rogaška |
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| 22 Dec 21 | r12 | KK RogaškaKK Rogaška | 65 - 95 | KK KrkaKK Krka |
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| 30 Dec 21 | r11 | KK PodčetrtekKK Podčetrtek | 61 - 81 | KK RogaškaKK Rogaška |
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| 08 Jan 22 | r13 | KD IlirijaKD Ilirija | 93 - 73 | KK RogaškaKK Rogaška |
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| 15 Jan 22 | r14 | KK RogaškaKK Rogaška | 84 - 80 | Helios SunsHelios Suns |
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| 29 Jan 22 | r16 | KK RogaškaKK Rogaška | 86 - 78 | KK ŠenčurKK Šenčur |
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| 04 Feb 22 | r17 | KK Zlatorog LaškoKK Zlatorog L | 81 - 89 | KK RogaškaKK Rogaška |
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| 23 Feb 22 | r18 | KK RogaškaKK Rogaška | 97 - 86 | KK ŠentjurKK Šentjur |
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| 26 Feb 22 | r15 | KD Hopsi PolzelaKD Hopsi Polz | 74 - 81 | KK RogaškaKK Rogaška |
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| 05 Mar 22 | r01 | KK RogaškaKK Rogaška | 94 - 77 | KK ŠentjurKK Šentjur |
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| 12 Mar 22 | r02 | KK RogaškaKK Rogaška | 70 - 56 | KK Triglav KranjKK Triglav Kr |
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| 16 Mar 22 | r03 | KD Hopsi PolzelaKD Hopsi Polz | 83 - 97 | KK RogaškaKK Rogaška |
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| 09 Apr 22 | r06 | KK ŠentjurKK Šentjur | 89 - 77 | KK RogaškaKK Rogaška |
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| 13 Apr 22 | r04 | KK RogaškaKK Rogaška | 92 - 76 | KK Zlatorog LaškoKK Zlatorog L |
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| 16 Apr 22 | r07 | KK Triglav KranjKK Triglav Kr | 90 - 80 | KK RogaškaKK Rogaška |
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| 23 Apr 22 | r08 | KK RogaškaKK Rogaška | 116 - 99 | KD Hopsi PolzelaKD Hopsi Polz |
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| 27 Apr 22 | r09 | KK Zlatorog LaškoKK Zlatorog L | 90 - 96 | KK RogaškaKK Rogaška |
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| 04 May 22 | r00 | KK ŠenčurKK Šenčur | 92 - 96 | KK RogaškaKK Rogaška |
| 07 May 22 | r00 | KK RogaškaKK Rogaška | 87 - 72 | KK ŠenčurKK Šenčur |
Team 2021-2022 Schedules
KD Hopsi Polzela
KD Ilirija
KK Cedevita Olimpija
KK Domžale
KK Krka
KK Podčetrtek
KK Rogaška
KK Šenčur
KK Šentjur
KK Škofja Loka
KK Zlatorog Laško
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