| 02 Oct 21 | r01  | Helios SunsHelios Suns | 98 - 77 | KD Hopsi PolzelaKD Hopsi Polz |
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| 09 Oct 21 | r02 | KK Triglav KranjKK Triglav Kr | 84 - 97 | KD Hopsi PolzelaKD Hopsi Polz |
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| 16 Oct 21 | r03 | KD Hopsi PolzelaKD Hopsi Polz | 77 - 84 | KK ŠenčurKK Šenčur |
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| 25 Oct 21 | r04 | KK Zlatorog LaškoKK Zlatorog L | 81 - 78 | KD Hopsi PolzelaKD Hopsi Polz |
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| 30 Oct 21 | r05 | KD Hopsi PolzelaKD Hopsi Polz | 91 - 82 | KK ŠentjurKK Šentjur |
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| 05 Nov 21 | r06 | KK RogaškaKK Rogaška | 87 - 90 | KD Hopsi PolzelaKD Hopsi Polz |
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| 14 Nov 21 | r07 | KD Hopsi PolzelaKD Hopsi Polz | 82 - 90 | KK PodčetrtekKK Podčetrtek |
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| 04 Dec 21 | r09 | KD Hopsi PolzelaKD Hopsi Polz | 82 - 81 | KD IlirijaKD Ilirija |
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| 07 Dec 21 | r08 | KK KrkaKK Krka | 102 - 89 | KD Hopsi PolzelaKD Hopsi Polz |
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| 10 Dec 21 | r10 | KD Hopsi PolzelaKD Hopsi Polz | 73 - 85 | Helios SunsHelios Suns |
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| 18 Dec 21 | r11 | KD Hopsi PolzelaKD Hopsi Polz | 89 - 87 | KK Triglav KranjKK Triglav Kr |
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| 28 Dec 21 | r12 | KK ŠenčurKK Šenčur | 100 - 82 | KD Hopsi PolzelaKD Hopsi Polz |
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| 08 Jan 22 | r13 | KD Hopsi PolzelaKD Hopsi Polz | 98 - 87 | KK Zlatorog LaškoKK Zlatorog L |
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| 15 Jan 22 | r14 | KK ŠentjurKK Šentjur | 89 - 79 | KD Hopsi PolzelaKD Hopsi Polz |
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| 29 Jan 22 | r16 | KK PodčetrtekKK Podčetrtek | 99 - 92 | KD Hopsi PolzelaKD Hopsi Polz |
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| 02 Feb 22 | r17 | KD Hopsi PolzelaKD Hopsi Polz | 74 - 78 | KK KrkaKK Krka |
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| 12 Feb 22 | r18 | KD IlirijaKD Ilirija | 99 - 80 | KD Hopsi PolzelaKD Hopsi Polz |
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| 26 Feb 22 | r15 | KD Hopsi PolzelaKD Hopsi Polz | 74 - 81 | KK RogaškaKK Rogaška |
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| 05 Mar 22 | r01 | KD Hopsi PolzelaKD Hopsi Polz | 72 - 84 | KK Zlatorog LaškoKK Zlatorog L |
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| 16 Mar 22 | r03 | KD Hopsi PolzelaKD Hopsi Polz | 83 - 97 | KK RogaškaKK Rogaška |
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| 26 Mar 22 | r04 | KK Triglav KranjKK Triglav Kr | 81 - 95 | KD Hopsi PolzelaKD Hopsi Polz |
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| 02 Apr 22 | r05 | KD Hopsi PolzelaKD Hopsi Polz | 97 - 85 | KK ŠentjurKK Šentjur |
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| 09 Apr 22 | r06 | KK Zlatorog LaškoKK Zlatorog L | 77 - 66 | KD Hopsi PolzelaKD Hopsi Polz |
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| 20 Apr 22 | r10 | KK ŠentjurKK Šentjur | 89 - 73 | KD Hopsi PolzelaKD Hopsi Polz |
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| 23 Apr 22 | r08 | KK RogaškaKK Rogaška | 116 - 99 | KD Hopsi PolzelaKD Hopsi Polz |
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| 27 Apr 22 | r09 | KD Hopsi PolzelaKD Hopsi Polz | 93 - 81 | KK Triglav KranjKK Triglav Kr |
Team 2021-2022 Schedules
KD Hopsi Polzela
KD Ilirija
KK Cedevita Olimpija
KK Domžale
KK Krka
KK Podčetrtek
KK Rogaška
KK Šenčur
KK Šentjur
KK Škofja Loka
KK Zlatorog Laško
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