| 21 Aug 21 | r01  | SV SpakenburgSV Spakenburg | 2 - 2 | Jong VolendamJong Volendam |
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| 28 Aug 21 | r02 | SVV ScheveningenSVV Schevenin | 2 - 1 | SV SpakenburgSV Spakenburg |
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| 04 Sep 21 | r03 | SV SpakenburgSV Spakenburg | 2 - 3 | VV KatwijkVV Katwijk |
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| 11 Sep 21 | r04 | Kozakken BoysKozakken Boys | 3 - 3 | SV SpakenburgSV Spakenburg |
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| 18 Sep 21 | r05 | SV SpakenburgSV Spakenburg | 2 - 0 | GVVVGVVV |
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| 25 Sep 21 | r06 | Rijnsburgse BoysRijnsburgse B | 3 - 1 | SV SpakenburgSV Spakenburg |
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| 02 Oct 21 | r07 | VV ASWHVV ASWH | 3 - 1 | SV SpakenburgSV Spakenburg |
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| 09 Oct 21 | r08 | SV SpakenburgSV Spakenburg | 4 - 2 | Excelsior MaassluisExcelsior Maa |
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| 16 Oct 21 | r09 | HHC HardenbergHHC Hardenber | 3 - 3 | SV SpakenburgSV Spakenburg |
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| 30 Oct 21 | r10 | SV SpakenburgSV Spakenburg | 1 - 3 | Quick BoysQuick Boys |
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| 06 Nov 21 | r11 | Amsterdamsche FCAmsterdamsche | 5 - 1 | SV SpakenburgSV Spakenburg |
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| 13 Nov 21 | r12 | SV SpakenburgSV Spakenburg | 2 - 0 | VV NoordwijkVV Noordwijk |
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| 27 Nov 21 | r14 | SV SpakenburgSV Spakenburg | 2 - 0 | Koninklijke HFCKoninklijke H |
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| 19 Feb 22 | r15 | De TreffersDe Treffers | 1 - 0 | SV SpakenburgSV Spakenburg |
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| 26 Feb 22 | r16 | Jong SpartaJong Sparta | 0 - 6 | SV SpakenburgSV Spakenburg |
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| 05 Mar 22 | r17 | SV SpakenburgSV Spakenburg | 2 - 0 | SV TECSV TEC |
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| 08 Mar 22 | r13 | IJsselmeervogelsIJsselmeervog | 2 - 2 | SV SpakenburgSV Spakenburg |
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| 22 Mar 22 | r21 | SV SpakenburgSV Spakenburg | 2 - 0 | HHC HardenbergHHC Hardenber |
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| 26 Mar 22 | r20 | VV NoordwijkVV Noordwijk | 2 - 3 | SV SpakenburgSV Spakenburg |
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| 29 Mar 22 | r18 | GVVVGVVV | 4 - 0 | SV SpakenburgSV Spakenburg |
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| 05 Apr 22 | r22 | VV KatwijkVV Katwijk | 2 - 2 | SV SpakenburgSV Spakenburg |
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| 09 Apr 22 | r24 | SV SpakenburgSV Spakenburg | 0 - 3 | Jong SpartaJong Sparta |
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| 12 Apr 22 | r19 | SV SpakenburgSV Spakenburg | 1 - 2 | Amsterdamsche FCAmsterdamsche |
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| 16 Apr 22 | r25 | Quick BoysQuick Boys | 1 - 0 | SV SpakenburgSV Spakenburg |
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| 18 Apr 22 | r26 | SV SpakenburgSV Spakenburg | 3 - 1 | Kozakken BoysKozakken Boys |
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| 23 Apr 22 | r27 | SV TECSV TEC | 2 - 0 | SV SpakenburgSV Spakenburg |
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| 26 Apr 22 | r23 | SV SpakenburgSV Spakenburg | 1 - 0 | VV ASWHVV ASWH |
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| 30 Apr 22 | r28 | SV SpakenburgSV Spakenburg | 5 - 2 | De TreffersDe Treffers |
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| 07 May 22 | r29 | Jong VolendamJong Volendam | 2 - 5 | SV SpakenburgSV Spakenburg |
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| 14 May 22 | r30 | SV SpakenburgSV Spakenburg | 1 - 1 | IJsselmeervogelsIJsselmeervog |
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| 21 May 22 | r31 | Koninklijke HFCKoninklijke H | 2 - 3 | SV SpakenburgSV Spakenburg |
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| 26 May 22 | r32 | SV SpakenburgSV Spakenburg | 1 - 1 | SVV ScheveningenSVV Schevenin |
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| 28 May 22 | r33 | Excelsior MaassluisExcelsior Maa | 4 - 0 | SV SpakenburgSV Spakenburg |
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| 04 Jun 22 | r34 | SV SpakenburgSV Spakenburg | 2 - 1 | Rijnsburgse BoysRijnsburgse B |
Team 2021-2022 Schedules
ACV
AFC
BVV Barendrecht
De Treffers
Excelsior Maassluis
GVVV
HHC Hardenberg
HSV Hoek
IJsselmeervogels
Jong Almere City
Jong Sparta Rotterdam
Koninklijke HFC
Kozakken Boys
Quick Boys
Rijnsburgse Boys
RKAV Volendam
SV Spakenburg
VV Katwijk
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