| 04 Sep 21 | r41  | CD CoriaCD Coria | 2 - 0 | AntequeraAntequera |
| 05 Sep 21 | r41 | MontijoMontijo | 0 - 1 | Las Palmas AtléticoLas Palmas At |
| 05 Sep 21 | r41 | Don BenitoDon Benito | 1 - 1 | MensajeroMensajero |
| 05 Sep 21 | r41 | Cadiz BCadiz B | 1 - 0 | San Roque LepeSan Roque Lep |
| 05 Sep 21 | r41 | AD Ceuta FCAD Ceuta FC | 2 - 3 | VillanovenseVillanovense |
| 05 Sep 21 | r41 | TamaraceiteTamaraceite | 3 - 4 | UD San FernandoUD San Fernan |
| 05 Sep 21 | r41 | Panadería PulidoPanadería Pul | 1 - 3 | Mérida ADMérida AD |
| 05 Sep 21 | r41 | VélezVélez | 1 - 2 | CacereñoCacereño |
| 05 Sep 21 | r41 | Xerez DeportivoXerez Deporti | 1 - 5 | CordobaCordoba |
| |
| 12 Sep 21 | r42 | San Roque LepeSan Roque Lep | 1 - 2 | CD CoriaCD Coria |
| 12 Sep 21 | r42 | Mérida ADMérida AD | 1 - 1 | AD Ceuta FCAD Ceuta FC |
| 12 Sep 21 | r42 | UD San FernandoUD San Fernan | 1 - 2 | MontijoMontijo |
| 12 Sep 21 | r42 | Las Palmas AtléticoLas Palmas At | 2 - 2 | Panadería PulidoPanadería Pul |
| 12 Sep 21 | r42 | MensajeroMensajero | 2 - 2 | TamaraceiteTamaraceite |
| 12 Sep 21 | r42 | CacereñoCacereño | 2 - 0 | Xerez DeportivoXerez Deporti |
| 12 Sep 21 | r42 | CordobaCordoba | 3 - 1 | Cadiz BCadiz B |
| 12 Sep 21 | r42 | AntequeraAntequera | 2 - 1 | Don BenitoDon Benito |
| 12 Sep 21 | r42 | VillanovenseVillanovense | 2 - 0 | VélezVélez |
| |
| 18 Sep 21 | r43 | Cadiz BCadiz B | 0 - 1 | CacereñoCacereño |
| 19 Sep 21 | r43 | MontijoMontijo | 0 - 0 | Panadería PulidoPanadería Pul |
| 19 Sep 21 | r43 | AD Ceuta FCAD Ceuta FC | 0 - 0 | Las Palmas AtléticoLas Palmas At |
| 19 Sep 21 | r43 | UD San FernandoUD San Fernan | 0 - 1 | MensajeroMensajero |
| 19 Sep 21 | r43 | TamaraceiteTamaraceite | 0 - 2 | AntequeraAntequera |
| 19 Sep 21 | r43 | Xerez DeportivoXerez Deporti | 2 - 0 | VillanovenseVillanovense |
| 19 Sep 21 | r43 | VélezVélez | 0 - 0 | Mérida ADMérida AD |
| 19 Sep 21 | r43 | CD CoriaCD Coria | 0 - 3 | CordobaCordoba |
| 19 Sep 21 | r43 | Don BenitoDon Benito | 0 - 0 | San Roque LepeSan Roque Lep |
| |
| 26 Sep 21 | r44 | CacereñoCacereño | 1 - 1 | CD CoriaCD Coria |
| 26 Sep 21 | r44 | Las Palmas AtléticoLas Palmas At | 2 - 0 | VélezVélez |
| 26 Sep 21 | r44 | AntequeraAntequera | 1 - 0 | UD San FernandoUD San Fernan |
| 26 Sep 21 | r44 | San Roque LepeSan Roque Lep | 1 - 0 | TamaraceiteTamaraceite |
| 26 Sep 21 | r44 | Panadería PulidoPanadería Pul | 1 - 2 | AD Ceuta FCAD Ceuta FC |
| 26 Sep 21 | r44 | CordobaCordoba | 3 - 2 | Don BenitoDon Benito |
| 26 Sep 21 | r44 | VillanovenseVillanovense | 1 - 1 | Cadiz BCadiz B |
| 26 Sep 21 | r44 | Mérida ADMérida AD | 0 - 0 | Xerez DeportivoXerez Deporti |
| |
| 03 Oct 21 | r45 | Xerez DeportivoXerez Deporti | 2 - 1 | Las Palmas AtléticoLas Palmas At |
| 03 Oct 21 | r45 | VélezVélez | 4 - 0 | Panadería PulidoPanadería Pul |
| 03 Oct 21 | r45 | MontijoMontijo | 1 - 0 | AD Ceuta FCAD Ceuta FC |
| 03 Oct 21 | r45 | TamaraceiteTamaraceite | 1 - 1 | CordobaCordoba |
| 03 Oct 21 | r45 | MensajeroMensajero | 3 - 3 | AntequeraAntequera |
| 03 Oct 21 | r45 | UD San FernandoUD San Fernan | 0 - 0 | San Roque LepeSan Roque Lep |
| 03 Oct 21 | r45 | Cadiz BCadiz B | 0 - 2 | Mérida ADMérida AD |
| 03 Oct 21 | r45 | Don BenitoDon Benito | 1 - 1 | CacereñoCacereño |
| 03 Oct 21 | r45 | CD CoriaCD Coria | 0 - 0 | VillanovenseVillanovense |
| |
| 09 Oct 21 | r46 | Panadería PulidoPanadería Pul | 0 - 1 | Xerez DeportivoXerez Deporti |
| 10 Oct 21 | r46 | CacereñoCacereño | 1 - 0 | TamaraceiteTamaraceite |
| 10 Oct 21 | r46 | San Roque LepeSan Roque Lep | 4 - 1 | MensajeroMensajero |
| 10 Oct 21 | r46 | CordobaCordoba | 4 - 1 | UD San FernandoUD San Fernan |
| 10 Oct 21 | r46 | AD Ceuta FCAD Ceuta FC | 1 - 0 | VélezVélez |
| 10 Oct 21 | r46 | Las Palmas AtléticoLas Palmas At | 1 - 1 | Cadiz BCadiz B |
| 10 Oct 21 | r46 | VillanovenseVillanovense | 0 - 2 | Don BenitoDon Benito |
| 10 Oct 21 | r46 | Mérida ADMérida AD | 0 - 1 | CD CoriaCD Coria |
| 10 Oct 21 | r46 | AntequeraAntequera | 2 - 1 | MontijoMontijo |
| |
| 17 Oct 21 | r47 | CD CoriaCD Coria | 3 - 1 | Las Palmas AtléticoLas Palmas At |
| 17 Oct 21 | r47 | Xerez DeportivoXerez Deporti | 2 - 2 | AD Ceuta FCAD Ceuta FC |
| 17 Oct 21 | r47 | MontijoMontijo | 1 - 0 | VélezVélez |
| 17 Oct 21 | r47 | TamaraceiteTamaraceite | 0 - 1 | VillanovenseVillanovense |
| 17 Oct 21 | r47 | UD San FernandoUD San Fernan | 1 - 1 | CacereñoCacereño |
| 17 Oct 21 | r47 | Cadiz BCadiz B | 2 - 1 | Panadería PulidoPanadería Pul |
| 17 Oct 21 | r47 | Don BenitoDon Benito | 2 - 2 | Mérida ADMérida AD |
| 17 Oct 21 | r47 | AntequeraAntequera | 0 - 0 | San Roque LepeSan Roque Lep |
| |
| 23 Oct 21 | r48 | San Roque LepeSan Roque Lep | 1 - 2 | MontijoMontijo |
| 23 Oct 21 | r48 | CordobaCordoba | 2 - 0 | AntequeraAntequera |
| 24 Oct 21 | r48 | Mérida ADMérida AD | 6 - 1 | TamaraceiteTamaraceite |
| 24 Oct 21 | r48 | CacereñoCacereño | 1 - 1 | MensajeroMensajero |
| 24 Oct 21 | r48 | VillanovenseVillanovense | 2 - 0 | UD San FernandoUD San Fernan |
| 24 Oct 21 | r48 | AD Ceuta FCAD Ceuta FC | 2 - 0 | Cadiz BCadiz B |
| 24 Oct 21 | r48 | VélezVélez | 5 - 2 | Xerez DeportivoXerez Deporti |
| 24 Oct 21 | r48 | Las Palmas AtléticoLas Palmas At | 1 - 4 | Don BenitoDon Benito |
| 24 Oct 21 | r48 | Panadería PulidoPanadería Pul | 0 - 1 | CD CoriaCD Coria |
| |
| 30 Oct 21 | r49 | Cadiz BCadiz B | 0 - 2 | VélezVélez |
| 30 Oct 21 | r49 | San Roque LepeSan Roque Lep | 0 - 1 | CordobaCordoba |
| 31 Oct 21 | r49 | AntequeraAntequera | 2 - 2 | CacereñoCacereño |
| 31 Oct 21 | r49 | Don BenitoDon Benito | 1 - 1 | Panadería PulidoPanadería Pul |
| 31 Oct 21 | r49 | CD CoriaCD Coria | 2 - 2 | AD Ceuta FCAD Ceuta FC |
| 31 Oct 21 | r49 | MontijoMontijo | 2 - 0 | Xerez DeportivoXerez Deporti |
| 31 Oct 21 | r49 | TamaraceiteTamaraceite | 0 - 0 | Las Palmas AtléticoLas Palmas At |
| 31 Oct 21 | r49 | MensajeroMensajero | 1 - 0 | VillanovenseVillanovense |
| 31 Oct 21 | r49 | UD San FernandoUD San Fernan | 0 - 1 | Mérida ADMérida AD |
| |
| 06 Nov 21 | r410 | CordobaCordoba | 3 - 1 | MontijoMontijo |
| 07 Nov 21 | r410 | CacereñoCacereño | 1 - 1 | San Roque LepeSan Roque Lep |
| 07 Nov 21 | r410 | Mérida ADMérida AD | 1 - 1 | MensajeroMensajero |
| 07 Nov 21 | r410 | AD Ceuta FCAD Ceuta FC | 0 - 0 | Don BenitoDon Benito |
| 07 Nov 21 | r410 | Las Palmas AtléticoLas Palmas At | 1 - 0 | UD San FernandoUD San Fernan |
| 07 Nov 21 | r410 | Panadería PulidoPanadería Pul | 1 - 1 | TamaraceiteTamaraceite |
| 07 Nov 21 | r410 | VillanovenseVillanovense | 1 - 1 | AntequeraAntequera |
| 07 Nov 21 | r410 | VélezVélez | 2 - 1 | CD CoriaCD Coria |
| 07 Nov 21 | r410 | Xerez DeportivoXerez Deporti | 0 - 1 | Cadiz BCadiz B |
| |
| 13 Nov 21 | r411 | San Roque LepeSan Roque Lep | 2 - 0 | VillanovenseVillanovense |
| 14 Nov 21 | r411 | MontijoMontijo | 1 - 1 | Cadiz BCadiz B |
| 14 Nov 21 | r411 | MensajeroMensajero | 1 - 2 | Las Palmas AtléticoLas Palmas At |
| 14 Nov 21 | r411 | UD San FernandoUD San Fernan | 1 - 0 | Panadería PulidoPanadería Pul |
| 14 Nov 21 | r411 | TamaraceiteTamaraceite | 0 - 2 | AD Ceuta FCAD Ceuta FC |
| 14 Nov 21 | r411 | CordobaCordoba | 5 - 0 | CacereñoCacereño |
| 14 Nov 21 | r411 | AntequeraAntequera | 0 - 2 | Mérida ADMérida AD |
| 14 Nov 21 | r411 | Don BenitoDon Benito | 4 - 1 | VélezVélez |
| 14 Nov 21 | r411 | CD CoriaCD Coria | 2 - 1 | Xerez DeportivoXerez Deporti |
| |
| 20 Nov 21 | r412 | VillanovenseVillanovense | 1 - 0 | CordobaCordoba |
| 21 Nov 21 | r412 | Cadiz BCadiz B | 0 - 1 | CD CoriaCD Coria |
| 21 Nov 21 | r412 | CacereñoCacereño | 2 - 0 | MontijoMontijo |
| 21 Nov 21 | r412 | AD Ceuta FCAD Ceuta FC | 1 - 0 | UD San FernandoUD San Fernan |
| 21 Nov 21 | r412 | VélezVélez | 2 - 0 | TamaraceiteTamaraceite |
| 21 Nov 21 | r412 | Xerez DeportivoXerez Deporti | 1 - 0 | Don BenitoDon Benito |
| 21 Nov 21 | r412 | Las Palmas AtléticoLas Palmas At | 1 - 2 | AntequeraAntequera |
| 21 Nov 21 | r412 | Mérida ADMérida AD | 0 - 1 | San Roque LepeSan Roque Lep |
| |
| 27 Nov 21 | r413 | MontijoMontijo | 1 - 0 | CD CoriaCD Coria |
| 27 Nov 21 | r413 | CordobaCordoba | 3 - 0 | Mérida ADMérida AD |
| 27 Nov 21 | r413 | Don BenitoDon Benito | 2 - 3 | Cadiz BCadiz B |
| 27 Nov 21 | r413 | CacereñoCacereño | 0 - 1 | VillanovenseVillanovense |
| 28 Nov 21 | r413 | San Roque LepeSan Roque Lep | 1 - 1 | Las Palmas AtléticoLas Palmas At |
| 28 Nov 21 | r413 | AntequeraAntequera | 1 - 2 | Panadería PulidoPanadería Pul |
| 28 Nov 21 | r413 | MensajeroMensajero | 1 - 3 | AD Ceuta FCAD Ceuta FC |
| 28 Nov 21 | r413 | UD San FernandoUD San Fernan | 0 - 0 | VélezVélez |
| 28 Nov 21 | r413 | TamaraceiteTamaraceite | 1 - 0 | Xerez DeportivoXerez Deporti |
| |
| 04 Dec 21 | r414 | VillanovenseVillanovense | 2 - 0 | MontijoMontijo |
| 05 Dec 21 | r414 | Cadiz BCadiz B | 3 - 2 | TamaraceiteTamaraceite |
| 05 Dec 21 | r414 | AD Ceuta FCAD Ceuta FC | 1 - 0 | AntequeraAntequera |
| 05 Dec 21 | r414 | VélezVélez | 3 - 0 | MensajeroMensajero |
| 05 Dec 21 | r414 | Xerez DeportivoXerez Deporti | 1 - 0 | UD San FernandoUD San Fernan |
| 05 Dec 21 | r414 | Las Palmas AtléticoLas Palmas At | 2 - 2 | CordobaCordoba |
| 05 Dec 21 | r414 | Panadería PulidoPanadería Pul | 0 - 1 | San Roque LepeSan Roque Lep |
| 05 Dec 21 | r414 | Mérida ADMérida AD | 0 - 1 | CacereñoCacereño |
| 05 Dec 21 | r414 | CD CoriaCD Coria | 1 - 0 | Don BenitoDon Benito |
| |
| 08 Dec 21 | r44 | MensajeroMensajero | 1 - 0 | MontijoMontijo |
| |
| 12 Dec 21 | r415 | CacereñoCacereño | 3 - 2 | Las Palmas AtléticoLas Palmas At |
| 12 Dec 21 | r415 | CordobaCordoba | 4 - 0 | Panadería PulidoPanadería Pul |
| 12 Dec 21 | r415 | MontijoMontijo | 3 - 1 | Don BenitoDon Benito |
| 12 Dec 21 | r415 | TamaraceiteTamaraceite | 1 - 0 | CD CoriaCD Coria |
| 12 Dec 21 | r415 | San Roque LepeSan Roque Lep | 2 - 2 | AD Ceuta FCAD Ceuta FC |
| 12 Dec 21 | r415 | MensajeroMensajero | 0 - 0 | Xerez DeportivoXerez Deporti |
| 12 Dec 21 | r415 | UD San FernandoUD San Fernan | 0 - 0 | Cadiz BCadiz B |
| 12 Dec 21 | r415 | VillanovenseVillanovense | 1 - 0 | Mérida ADMérida AD |
| 12 Dec 21 | r415 | AntequeraAntequera | 3 - 1 | VélezVélez |
| |
| 18 Dec 21 | r416 | Panadería PulidoPanadería Pul | 0 - 2 | CacereñoCacereño |
| 19 Dec 21 | r416 | CD CoriaCD Coria | 2 - 2 | UD San FernandoUD San Fernan |
| 19 Dec 21 | r416 | Don BenitoDon Benito | 2 - 0 | TamaraceiteTamaraceite |
| 19 Dec 21 | r416 | MontijoMontijo | 2 - 0 | Mérida ADMérida AD |
| 19 Dec 21 | r416 | AD Ceuta FCAD Ceuta FC | 0 - 0 | CordobaCordoba |
| 19 Dec 21 | r416 | VélezVélez | 1 - 0 | San Roque LepeSan Roque Lep |
| 19 Dec 21 | r416 | Cadiz BCadiz B | 0 - 0 | MensajeroMensajero |
| 19 Dec 21 | r416 | Las Palmas AtléticoLas Palmas At | 1 - 1 | VillanovenseVillanovense |
| 19 Dec 21 | r416 | Xerez DeportivoXerez Deporti | 1 - 0 | AntequeraAntequera |
| |
| 22 Dec 21 | r47 | MensajeroMensajero | 1 - 1 | CordobaCordoba |
| |
| 09 Jan 22 | r417 | Mérida ADMérida AD | 2 - 0 | Las Palmas AtléticoLas Palmas At |
| 09 Jan 22 | r417 | VillanovenseVillanovense | 6 - 0 | Panadería PulidoPanadería Pul |
| 09 Jan 22 | r417 | CacereñoCacereño | 2 - 0 | AD Ceuta FCAD Ceuta FC |
| 09 Jan 22 | r417 | MensajeroMensajero | 0 - 1 | CD CoriaCD Coria |
| 09 Jan 22 | r417 | UD San FernandoUD San Fernan | 1 - 3 | Don BenitoDon Benito |
| 09 Jan 22 | r417 | TamaraceiteTamaraceite | 2 - 1 | MontijoMontijo |
| 09 Jan 22 | r417 | CordobaCordoba | 4 - 1 | VélezVélez |
| 09 Jan 22 | r417 | AntequeraAntequera | 1 - 1 | Cadiz BCadiz B |
| |
| 18 Jan 22 | r412 | Panadería PulidoPanadería Pul | 2 - 2 | MensajeroMensajero |
| |
| 23 Jan 22 | r418 | Mérida ADMérida AD | 2 - 1 | Panadería PulidoPanadería Pul |
| 23 Jan 22 | r418 | San Roque LepeSan Roque Lep | 0 - 0 | Cadiz BCadiz B |
| 23 Jan 22 | r418 | VillanovenseVillanovense | 0 - 1 | AD Ceuta FCAD Ceuta FC |
| 23 Jan 22 | r418 | MensajeroMensajero | 1 - 2 | Don BenitoDon Benito |
| 23 Jan 22 | r418 | Las Palmas AtléticoLas Palmas At | 0 - 3 | MontijoMontijo |
| 23 Jan 22 | r418 | AntequeraAntequera | 0 - 0 | CD CoriaCD Coria |
| 23 Jan 22 | r418 | CordobaCordoba | 4 - 0 | Xerez DeportivoXerez Deporti |
| |
| 29 Jan 22 | r419  | Xerez DeportivoXerez Deporti | 1 - 0 | CacereñoCacereño |
| 30 Jan 22 | r419 | MontijoMontijo | 2 - 0 | UD San FernandoUD San Fernan |
| 30 Jan 22 | r419 | VélezVélez | 2 - 1 | VillanovenseVillanovense |
| 30 Jan 22 | r419 | AD Ceuta FCAD Ceuta FC | 0 - 1 | Mérida ADMérida AD |
| 30 Jan 22 | r419 | CD CoriaCD Coria | 2 - 0 | San Roque LepeSan Roque Lep |
| 30 Jan 22 | r419 | TamaraceiteTamaraceite | 3 - 0 | MensajeroMensajero |
| 30 Jan 22 | r419 | Panadería PulidoPanadería Pul | 1 - 1 | Las Palmas AtléticoLas Palmas At |
| 30 Jan 22 | r419 | Cadiz BCadiz B | 0 - 4 | CordobaCordoba |
| 30 Jan 22 | r419 | Don BenitoDon Benito | 1 - 1 | AntequeraAntequera |
| |
| 02 Feb 22 | r417 | San Roque LepeSan Roque Lep | 4 - 2 | Xerez DeportivoXerez Deporti |
| |
| 02 Feb 22 | r418 | CacereñoCacereño | 2 - 0 | VélezVélez |
| |
| 06 Feb 22 | r420 | CacereñoCacereño | 1 - 1 | Cadiz BCadiz B |
| 06 Feb 22 | r420 | AntequeraAntequera | 3 - 1 | TamaraceiteTamaraceite |
| 06 Feb 22 | r420 | San Roque LepeSan Roque Lep | 1 - 0 | Don BenitoDon Benito |
| 06 Feb 22 | r420 | VillanovenseVillanovense | 2 - 0 | Xerez DeportivoXerez Deporti |
| 06 Feb 22 | r420 | MensajeroMensajero | 2 - 0 | UD San FernandoUD San Fernan |
| 06 Feb 22 | r420 | Las Palmas AtléticoLas Palmas At | 0 - 2 | AD Ceuta FCAD Ceuta FC |
| 06 Feb 22 | r420 | Panadería PulidoPanadería Pul | 0 - 0 | MontijoMontijo |
| 06 Feb 22 | r420 | CordobaCordoba | 3 - 1 | CD CoriaCD Coria |
| |
| 13 Feb 22 | r421 | VélezVélez | 1 - 0 | Las Palmas AtléticoLas Palmas At |
| 13 Feb 22 | r421 | MontijoMontijo | 2 - 2 | MensajeroMensajero |
| 13 Feb 22 | r421 | AD Ceuta FCAD Ceuta FC | 3 - 1 | Panadería PulidoPanadería Pul |
| 13 Feb 22 | r421 | UD San FernandoUD San Fernan | 0 - 0 | AntequeraAntequera |
| 13 Feb 22 | r421 | TamaraceiteTamaraceite | 2 - 0 | San Roque LepeSan Roque Lep |
| 13 Feb 22 | r421 | Cadiz BCadiz B | 1 - 0 | VillanovenseVillanovense |
| 13 Feb 22 | r421 | Don BenitoDon Benito | 1 - 2 | CordobaCordoba |
| 13 Feb 22 | r421 | CD CoriaCD Coria | 1 - 3 | CacereñoCacereño |
| 13 Feb 22 | r421 | Xerez DeportivoXerez Deporti | 1 - 1 | Mérida ADMérida AD |
| |
| 16 Feb 22 | r420 | Mérida ADMérida AD | 2 - 0 | VélezVélez |
| |
| 20 Feb 22 | r422 | San Roque LepeSan Roque Lep | 3 - 1 | UD San FernandoUD San Fernan |
| 20 Feb 22 | r422 | CacereñoCacereño | 2 - 0 | Don BenitoDon Benito |
| 20 Feb 22 | r422 | VillanovenseVillanovense | 0 - 0 | CD CoriaCD Coria |
| 20 Feb 22 | r422 | AntequeraAntequera | 0 - 0 | MensajeroMensajero |
| 20 Feb 22 | r422 | Las Palmas AtléticoLas Palmas At | 1 - 0 | Xerez DeportivoXerez Deporti |
| 20 Feb 22 | r422 | AD Ceuta FCAD Ceuta FC | 0 - 0 | MontijoMontijo |
| 20 Feb 22 | r422 | Panadería PulidoPanadería Pul | 2 - 0 | VélezVélez |
| 20 Feb 22 | r422 | Mérida ADMérida AD | 2 - 1 | Cadiz BCadiz B |
| |
| 27 Feb 22 | r423 | Cadiz BCadiz B | 1 - 0 | Las Palmas AtléticoLas Palmas At |
| 27 Feb 22 | r423 | MontijoMontijo | 1 - 0 | AntequeraAntequera |
| 27 Feb 22 | r423 | Xerez DeportivoXerez Deporti | 1 - 0 | Panadería PulidoPanadería Pul |
| 27 Feb 22 | r423 | VélezVélez | 2 - 2 | AD Ceuta FCAD Ceuta FC |
| 27 Feb 22 | r423 | TamaraceiteTamaraceite | 0 - 1 | CacereñoCacereño |
| 27 Feb 22 | r423 | MensajeroMensajero | 0 - 0 | San Roque LepeSan Roque Lep |
| 27 Feb 22 | r423 | UD San FernandoUD San Fernan | 0 - 3 | CordobaCordoba |
| 27 Feb 22 | r423 | Don BenitoDon Benito | 1 - 0 | VillanovenseVillanovense |
| 27 Feb 22 | r423 | CD CoriaCD Coria | 1 - 1 | Mérida ADMérida AD |
| |
| 06 Mar 22 | r424 | CacereñoCacereño | 3 - 2 | UD San FernandoUD San Fernan |
| 06 Mar 22 | r424 | VillanovenseVillanovense | 3 - 0 | TamaraceiteTamaraceite |
| 06 Mar 22 | r424 | CordobaCordoba | 3 - 1 | MensajeroMensajero |
| 06 Mar 22 | r424 | VélezVélez | 0 - 3 | MontijoMontijo |
| 06 Mar 22 | r424 | Las Palmas AtléticoLas Palmas At | 3 - 1 | CD CoriaCD Coria |
| 06 Mar 22 | r424 | Panadería PulidoPanadería Pul | 1 - 0 | Cadiz BCadiz B |
| 06 Mar 22 | r424 | Mérida ADMérida AD | 3 - 0 | Don BenitoDon Benito |
| 06 Mar 22 | r424 | AD Ceuta FCAD Ceuta FC | 1 - 1 | Xerez DeportivoXerez Deporti |
| 06 Mar 22 | r424 | San Roque LepeSan Roque Lep | 0 - 2 | AntequeraAntequera |
| |
| 13 Mar 22 | r425 | Don BenitoDon Benito | 3 - 2 | Las Palmas AtléticoLas Palmas At |
| 13 Mar 22 | r425 | CD CoriaCD Coria | 1 - 2 | Panadería PulidoPanadería Pul |
| 13 Mar 22 | r425 | MontijoMontijo | 0 - 1 | San Roque LepeSan Roque Lep |
| 13 Mar 22 | r425 | Cadiz BCadiz B | 1 - 0 | AD Ceuta FCAD Ceuta FC |
| 13 Mar 22 | r425 | TamaraceiteTamaraceite | 0 - 3 | Mérida ADMérida AD |
| 13 Mar 22 | r425 | UD San FernandoUD San Fernan | 2 - 1 | VillanovenseVillanovense |
| 13 Mar 22 | r425 | AntequeraAntequera | 0 - 1 | CordobaCordoba |
| 13 Mar 22 | r425 | Xerez DeportivoXerez Deporti | 0 - 0 | VélezVélez |
| |
| 16 Mar 22 | r418 | UD San FernandoUD San Fernan | 3 - 2 | TamaraceiteTamaraceite |
| |
| 19 Mar 22 | r426 | CordobaCordoba | 2 - 1 | San Roque LepeSan Roque Lep |
| 19 Mar 22 | r426 | Xerez DeportivoXerez Deporti | 1 - 0 | MontijoMontijo |
| 20 Mar 22 | r426 | Mérida ADMérida AD | 4 - 1 | UD San FernandoUD San Fernan |
| 20 Mar 22 | r426 | CacereñoCacereño | 3 - 1 | AntequeraAntequera |
| 20 Mar 22 | r426 | VillanovenseVillanovense | 1 - 1 | MensajeroMensajero |
| 20 Mar 22 | r426 | AD Ceuta FCAD Ceuta FC | 3 - 1 | CD CoriaCD Coria |
| 20 Mar 22 | r426 | Las Palmas AtléticoLas Palmas At | 3 - 3 | TamaraceiteTamaraceite |
| 20 Mar 22 | r426 | Panadería PulidoPanadería Pul | 1 - 1 | Don BenitoDon Benito |
| 20 Mar 22 | r426 | VélezVélez | 0 - 0 | Cadiz BCadiz B |
| |
| 23 Mar 22 | r422 | CordobaCordoba | 4 - 0 | TamaraceiteTamaraceite |
| |
| 27 Mar 22 | r427 | MontijoMontijo | 1 - 1 | CordobaCordoba |
| 27 Mar 22 | r427 | AntequeraAntequera | 0 - 1 | VillanovenseVillanovense |
| 27 Mar 22 | r427 | Don BenitoDon Benito | 0 - 2 | AD Ceuta FCAD Ceuta FC |
| 27 Mar 22 | r427 | Cadiz BCadiz B | 0 - 0 | Xerez DeportivoXerez Deporti |
| 27 Mar 22 | r427 | MensajeroMensajero | 1 - 0 | Mérida ADMérida AD |
| 27 Mar 22 | r427 | UD San FernandoUD San Fernan | 3 - 2 | Las Palmas AtléticoLas Palmas At |
| 27 Mar 22 | r427 | TamaraceiteTamaraceite | 0 - 3 | Panadería PulidoPanadería Pul |
| 27 Mar 22 | r427 | San Roque LepeSan Roque Lep | 2 - 0 | CacereñoCacereño |
| 27 Mar 22 | r427 | CD CoriaCD Coria | 0 - 1 | VélezVélez |
| |
| 30 Mar 22 | r425 | MensajeroMensajero | 0 - 0 | CacereñoCacereño |
| |
| 03 Apr 22 | r428 | AD Ceuta FCAD Ceuta FC | 2 - 2 | TamaraceiteTamaraceite |
| 03 Apr 22 | r428 | Cadiz BCadiz B | 2 - 2 | MontijoMontijo |
| 03 Apr 22 | r428 | Las Palmas AtléticoLas Palmas At | 2 - 1 | MensajeroMensajero |
| 03 Apr 22 | r428 | Panadería PulidoPanadería Pul | 1 - 1 | UD San FernandoUD San Fernan |
| 03 Apr 22 | r428 | VillanovenseVillanovense | 0 - 0 | San Roque LepeSan Roque Lep |
| 03 Apr 22 | r428 | VélezVélez | 0 - 0 | Don BenitoDon Benito |
| 03 Apr 22 | r428 | CacereñoCacereño | 2 - 2 | CordobaCordoba |
| 03 Apr 22 | r428 | Mérida ADMérida AD | 1 - 1 | AntequeraAntequera |
| 03 Apr 22 | r428 | Xerez DeportivoXerez Deporti | 1 - 1 | CD CoriaCD Coria |
| |
| 09 Apr 22 | r429 | CordobaCordoba | 2 - 0 | VillanovenseVillanovense |
| 09 Apr 22 | r429 | CD CoriaCD Coria | 3 - 2 | Cadiz BCadiz B |
| 10 Apr 22 | r429 | MontijoMontijo | 1 - 1 | CacereñoCacereño |
| 10 Apr 22 | r429 | San Roque LepeSan Roque Lep | 0 - 1 | Mérida ADMérida AD |
| 10 Apr 22 | r429 | AntequeraAntequera | 3 - 1 | Las Palmas AtléticoLas Palmas At |
| 10 Apr 22 | r429 | Don BenitoDon Benito | 1 - 2 | Xerez DeportivoXerez Deporti |
| 10 Apr 22 | r429 | MensajeroMensajero | 3 - 1 | Panadería PulidoPanadería Pul |
| 10 Apr 22 | r429 | UD San FernandoUD San Fernan | 1 - 0 | AD Ceuta FCAD Ceuta FC |
| 10 Apr 22 | r429 | TamaraceiteTamaraceite | 1 - 2 | VélezVélez |
| |
| 16 Apr 22 | r430 | Las Palmas AtléticoLas Palmas At | 2 - 3 | San Roque LepeSan Roque Lep |
| 16 Apr 22 | r430 | VillanovenseVillanovense | 2 - 0 | CacereñoCacereño |
| 16 Apr 22 | r430 | Mérida ADMérida AD | 0 - 1 | CordobaCordoba |
| 16 Apr 22 | r430 | CD CoriaCD Coria | 2 - 0 | MontijoMontijo |
| 17 Apr 22 | r430 | VélezVélez | 3 - 0 | UD San FernandoUD San Fernan |
| 17 Apr 22 | r430 | Xerez DeportivoXerez Deporti | 1 - 0 | TamaraceiteTamaraceite |
| 17 Apr 22 | r430 | Panadería PulidoPanadería Pul | 1 - 2 | AntequeraAntequera |
| 17 Apr 22 | r430 | Cadiz BCadiz B | 2 - 1 | Don BenitoDon Benito |
| 17 Apr 22 | r430 | AD Ceuta FCAD Ceuta FC | 2 - 0 | MensajeroMensajero |
| |
| 24 Apr 22 | r431 | CordobaCordoba | 5 - 1 | Las Palmas AtléticoLas Palmas At |
| 24 Apr 22 | r431 | TamaraceiteTamaraceite | 0 - 2 | Cadiz BCadiz B |
| 24 Apr 22 | r431 | Don BenitoDon Benito | 3 - 0 | CD CoriaCD Coria |
| 24 Apr 22 | r431 | MontijoMontijo | 2 - 1 | VillanovenseVillanovense |
| 24 Apr 22 | r431 | San Roque LepeSan Roque Lep | 2 - 0 | Panadería PulidoPanadería Pul |
| 24 Apr 22 | r431 | AntequeraAntequera | 3 - 1 | AD Ceuta FCAD Ceuta FC |
| 24 Apr 22 | r431 | MensajeroMensajero | 2 - 0 | VélezVélez |
| 24 Apr 22 | r431 | UD San FernandoUD San Fernan | 0 - 1 | Xerez DeportivoXerez Deporti |
| 24 Apr 22 | r431 | CacereñoCacereño | 1 - 2 | Mérida ADMérida AD |
| |
| 30 Apr 22 | r432 | Don BenitoDon Benito | 1 - 0 | MontijoMontijo |
| 01 May 22 | r432 | CD CoriaCD Coria | 4 - 1 | TamaraceiteTamaraceite |
| 01 May 22 | r432 | AD Ceuta FCAD Ceuta FC | 1 - 1 | San Roque LepeSan Roque Lep |
| 01 May 22 | r432 | VélezVélez | 1 - 1 | AntequeraAntequera |
| 01 May 22 | r432 | Cadiz BCadiz B | 5 - 0 | UD San FernandoUD San Fernan |
| 01 May 22 | r432 | Las Palmas AtléticoLas Palmas At | 1 - 2 | CacereñoCacereño |
| 01 May 22 | r432 | Panadería PulidoPanadería Pul | 3 - 3 | CordobaCordoba |
| 01 May 22 | r432 | Xerez DeportivoXerez Deporti | 2 - 1 | MensajeroMensajero |
| 01 May 22 | r432 | Mérida ADMérida AD | 1 - 0 | VillanovenseVillanovense |
| |
| 08 May 22 | r433 | VillanovenseVillanovense | 2 - 2 | Las Palmas AtléticoLas Palmas At |
| 08 May 22 | r433 | TamaraceiteTamaraceite | 0 - 0 | Don BenitoDon Benito |
| 08 May 22 | r433 | Mérida ADMérida AD | 2 - 1 | MontijoMontijo |
| 08 May 22 | r433 | CacereñoCacereño | 4 - 2 | Panadería PulidoPanadería Pul |
| 08 May 22 | r433 | CordobaCordoba | 3 - 2 | AD Ceuta FCAD Ceuta FC |
| 08 May 22 | r433 | San Roque LepeSan Roque Lep | 5 - 1 | VélezVélez |
| 08 May 22 | r433 | AntequeraAntequera | 2 - 0 | Xerez DeportivoXerez Deporti |
| 08 May 22 | r433 | MensajeroMensajero | 1 - 2 | Cadiz BCadiz B |
| 08 May 22 | r433 | UD San FernandoUD San Fernan | 0 - 1 | CD CoriaCD Coria |
| |
| 15 May 22 | r434 | Las Palmas AtléticoLas Palmas At | 1 - 3 | Mérida ADMérida AD |
| 15 May 22 | r434 | AD Ceuta FCAD Ceuta FC | 3 - 0 | CacereñoCacereño |
| 15 May 22 | r434 | VélezVélez | 1 - 2 | CordobaCordoba |
| 15 May 22 | r434 | Xerez DeportivoXerez Deporti | 0 - 1 | San Roque LepeSan Roque Lep |
| 15 May 22 | r434 | Cadiz BCadiz B | 1 - 0 | AntequeraAntequera |
| 15 May 22 | r434 | CD CoriaCD Coria | 3 - 2 | MensajeroMensajero |
| 15 May 22 | r434 | Don BenitoDon Benito | 2 - 2 | UD San FernandoUD San Fernan |
| 15 May 22 | r434 | MontijoMontijo | 1 - 7 | TamaraceiteTamaraceite |
| 15 May 22 | r434 | Panadería PulidoPanadería Pul | 1 - 3 | VillanovenseVillanovense |
Team 2021-2022 Schedules
Atlético Antoniano
Atlético Central
Atlético Paso
Atlético Sanluqueño
Badajoz
Betis Deportivo
Ciudad de Lucena
Don Benito
Estepona
Las Palmas Atlético
Linares Deportivo
Marbella
Mijas-Las Lagunas
Recreativo de Huelva
Sevilla Atlético
Tamaraceite
Tenerife B
Xerez
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