| 05 Sep 21 | r31  | Peña DeportivaPeña Deportiv | 1 - 0 | SD EjeaSD Ejea |
| |
| 12 Sep 21 | r32 | Huesca IIHuesca II | 1 - 1 | Peña DeportivaPeña Deportiv |
| |
| 19 Sep 21 | r33 | Peña DeportivaPeña Deportiv | 3 - 0 | BreaBrea |
| |
| 26 Sep 21 | r34 | NumanciaNumancia | 2 - 1 | Peña DeportivaPeña Deportiv |
| |
| 03 Oct 21 | r35 | Peña DeportivaPeña Deportiv | 1 - 0 | AE PratAE Prat |
| |
| 10 Oct 21 | r36 | CF BadalonaCF Badalona | 0 - 1 | Peña DeportivaPeña Deportiv |
| |
| 17 Oct 21 | r37 | Peña DeportivaPeña Deportiv | 2 - 2 | CE EuropaCE Europa |
| |
| 24 Oct 21 | r38 | AndratxAndratx | 4 - 3 | Peña DeportivaPeña Deportiv |
| |
| 31 Oct 21 | r39 | Peña DeportivaPeña Deportiv | 0 - 0 | CD Ibiza Islas PitiusasCD Ibiza Isla |
| |
| 07 Nov 21 | r310 | TarazonaTarazona | 1 - 0 | Peña DeportivaPeña Deportiv |
| |
| 14 Nov 21 | r311 | Peña DeportivaPeña Deportiv | 2 - 2 | CD TeruelCD Teruel |
| |
| 21 Nov 21 | r312 | EbroEbro | 1 - 1 | Peña DeportivaPeña Deportiv |
| |
| 28 Nov 21 | r313 | Peña DeportivaPeña Deportiv | 2 - 1 | Lleida EsportiuLleida Esport |
| |
| 05 Dec 21 | r314 | Espanyol BEspanyol B | 0 - 3 | Peña DeportivaPeña Deportiv |
| |
| 12 Dec 21 | r315 | Peña DeportivaPeña Deportiv | 1 - 1 | Cerdanyola del VallèsCerdanyola de |
| |
| 19 Dec 21 | r316 | Terrassa FCTerrassa FC | 1 - 2 | Peña DeportivaPeña Deportiv |
| |
| 09 Jan 22 | r317 | Peña DeportivaPeña Deportiv | 0 - 3 | FormenteraFormentera |
| |
| 23 Jan 22 | r318 | SD EjeaSD Ejea | 0 - 1 | Peña DeportivaPeña Deportiv |
| |
| 30 Jan 22 | r319 | Peña DeportivaPeña Deportiv | 0 - 2 | Huesca IIHuesca II |
| |
| 06 Feb 22 | r320  | BreaBrea | 1 - 1 | Peña DeportivaPeña Deportiv |
| |
| 13 Feb 22 | r321 | Peña DeportivaPeña Deportiv | 1 - 1 | NumanciaNumancia |
| |
| 20 Feb 22 | r322 | AE PratAE Prat | 1 - 0 | Peña DeportivaPeña Deportiv |
| |
| 27 Feb 22 | r323 | Peña DeportivaPeña Deportiv | 3 - 0 | CF BadalonaCF Badalona |
| |
| 06 Mar 22 | r324 | CE EuropaCE Europa | 1 - 0 | Peña DeportivaPeña Deportiv |
| |
| 13 Mar 22 | r325 | Peña DeportivaPeña Deportiv | 1 - 0 | AndratxAndratx |
| |
| 20 Mar 22 | r326 | CD Ibiza Islas PitiusasCD Ibiza Isla | 1 - 3 | Peña DeportivaPeña Deportiv |
| |
| 27 Mar 22 | r327 | Peña DeportivaPeña Deportiv | 3 - 1 | TarazonaTarazona |
| |
| 03 Apr 22 | r328 | CD TeruelCD Teruel | 1 - 1 | Peña DeportivaPeña Deportiv |
| |
| 10 Apr 22 | r329 | Peña DeportivaPeña Deportiv | 1 - 1 | EbroEbro |
| |
| 17 Apr 22 | r330 | Lleida EsportiuLleida Esport | 1 - 1 | Peña DeportivaPeña Deportiv |
| |
| 24 Apr 22 | r331 | Peña DeportivaPeña Deportiv | 1 - 0 | Espanyol BEspanyol B |
| |
| 01 May 22 | r332 | Cerdanyola del VallèsCerdanyola de | 0 - 3 | Peña DeportivaPeña Deportiv |
| |
| 08 May 22 | r333 | Peña DeportivaPeña Deportiv | 1 - 0 | Terrassa FCTerrassa FC |
| |
| 15 May 22 | r334 | FormenteraFormentera | 3 - 0 | Peña DeportivaPeña Deportiv |
Team 2021-2022 Schedules
Alcoyano
Atlético Baleares
Castellonense
Cieza
Deportiva Minera
Elche Ilicitano
Intercity
La Nucía
Lorca Deportiva
Malacitano
Mallorca B
Orihuela
Peña Deportiva
Poblense
Real Murcia Imperial
UCAM Murcia
Valencia Mestalla
Yeclano Deportivo
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