| 31 Aug 25 | r21   | AntequeraAntequera | 0 - 0 | CartagenaCartagena |
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| 05 Sep 25 | r22 | CartagenaCartagena | 3 - 2 | Atlético MadrileñoAtlético Madr |
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| 21 Sep 25 | r24  | CartagenaCartagena | 2 - 1 | HérculesHércules |
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| 24 Sep 25 | r23 | SabadellSabadell | 0 - 0 | CartagenaCartagena |
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| 28 Sep 25 | r25 | Atlético SanluqueñoAtlético Sanl | 3 - 0 | CartagenaCartagena |
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| 05 Oct 25 | r26 | CartagenaCartagena | 3 - 0 | TarazonaTarazona |
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| 12 Oct 25 | r27 | Sevilla AtléticoSevilla Atlét | 0 - 0 | CartagenaCartagena |
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| 17 Oct 25 | r28 | CartagenaCartagena | 2 - 0 | AlgecirasAlgeciras |
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| 26 Oct 25 | r29 | MarbellaMarbella | 0 - 0 | CartagenaCartagena |
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| 01 Nov 25 | r210 | CartagenaCartagena | 0 - 2 | Villarreal BVillarreal B |
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| 08 Nov 25 | r211 | TeruelTeruel | 1 - 2 | CartagenaCartagena |
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| 16 Nov 25 | r212 | CE EuropaCE Europa | 2 - 0 | CartagenaCartagena |
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| 23 Nov 25 | r213 | CartagenaCartagena | 0 - 0 | EldenseEldense |
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| 28 Nov 25 | r214 | Betis DeportivoBetis Deporti | 0 - 1 | CartagenaCartagena |
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| 08 Dec 25 | r215 | CartagenaCartagena | 0 - 1 | Real MurciaReal Murcia |
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| 14 Dec 25 | r216 | GimnàsticGimnàstic | 2 - 0 | CartagenaCartagena |
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| 21 Dec 25 | r217 | CartagenaCartagena | 3 - 0 | Juventud TorremolinosJuventud Torr |
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| 03 Jan 26 | r218 | AlcorcónAlcorcón | 1 - 1 | CartagenaCartagena |
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| 11 Jan 26 | r219 | CartagenaCartagena | 1 - 4 | IbizaIbiza |
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| 16 Jan 26 | r220 | Villarreal BVillarreal B | 1 - 0 | CartagenaCartagena |
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| 24 Jan 26 | r221 | CartagenaCartagena | 2 - 2 | CE EuropaCE Europa |
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| 30 Jan 26 | r222 | HérculesHércules | 2 - 0 | CartagenaCartagena |
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| 15 Feb 26 | r224 | CartagenaCartagena | 2 - 1 | MarbellaMarbella |
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| 22 Feb 26 | r225 | Real MurciaReal Murcia | 1 - 2 | CartagenaCartagena |
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| 25 Feb 26 | r223 | CartagenaCartagena | 1 - 0 | Sevilla AtléticoSevilla Atlét |
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| 01 Mar 26 | r226 | CartagenaCartagena | 0 - 0 | SabadellSabadell |
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| 08 Mar 26 | r227  | TarazonaTarazona | 0 - 0 | CartagenaCartagena |
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| 14 Mar 26 | r228 | CartagenaCartagena | 0 - 0 | TeruelTeruel |
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| 21 Mar 26 | r229 | Atlético MadrileñoAtlético Madr | 2 - 0 | CartagenaCartagena |
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| 28 Mar 26 | r230 | CartagenaCartagena | 1 - 0 | Atlético SanluqueñoAtlético Sanl |
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| 05 Apr 26 | r231 | Juventud TorremolinosJuventud Torr | - | CartagenaCartagena |
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| 12 Apr 26 | r232 | CartagenaCartagena | - | AntequeraAntequera |
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| 19 Apr 26 | r233 | EldenseEldense | 2 - 1 | CartagenaCartagena |
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| 26 Apr 26 | r234 | CartagenaCartagena | 1 - 0 | GimnàsticGimnàstic |
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| 03 May 26 | r235 | AlgecirasAlgeciras | - | CartagenaCartagena |
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| 10 May 26 | r236 | CartagenaCartagena | - | AlcorcónAlcorcón |
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| 17 May 26 | r237 | IbizaIbiza | - | CartagenaCartagena |
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| 24 May 26 | r238 | CartagenaCartagena | - | Betis DeportivoBetis Deporti |
Team 2025-2026 Schedules
Alcorcón
Algeciras
Antequera
Atlético Madrileño
Atlético Sanluqueño
Betis Deportivo
Cartagena
CE Europa
Eldense
Gimnàstic
Hércules
Ibiza
Juventud Torremolinos
Marbella
Real Murcia
Sabadell
Sevilla Atlético
Tarazona
Teruel
Villarreal B
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