| 02 May 22 | r01   | Northern Virginia FCNorthern Virg | 3 - 1 | Commonwealth Cardinals FCCommonwealth |
| 07 May 22 | r01 | Christos FCChristos FC | 3 - 0 | Patuxent Football AthletiPatuxent Foot |
| 08 May 22 | r01 | Virginia Beach United FCVirginia Beac | 1 - 2 | Northern Virginia FCNorthern Virg |
| 08 May 22 | r01 | Minneapolis CityMinneapolis C | 0 - 2 | Des Moines MenaceDes Moines Me |
| 08 May 22 | r01 | AFC Ann ArborAFC Ann Arbor | 5 - 0 | Oakland County FCOakland Count |
| 08 May 22 | r01 | Marin FC LegendsMarin FC Lege | 0 - 1 | Project 51OProject 51O |
| 09 May 22 | r01 | Dalton Red Wolves SCDalton Red Wo | 2 - 2 | Tennessee SCTennessee SC |
| 09 May 22 | r01 | Louisiana Krewe FCLouisiana Kre | 2 - 2 | LA Parish ACLA Parish AC |
| 11 May 22 | r01 | Kings Hammer FCKings Hammer | 0 - 1 | Fort Wayne FCFort Wayne FC |
| 11 May 22 | r01 | Nona FCNona FC | 1 - 0 | Weston FCWeston FC |
| |
| 12 May 22 | r02 | Boston City FCBoston City F | 2 - 0 | Western Mass PioneersWestern Mass |
| 12 May 22 | r02 | North Carolina Fusion U23North Carolin | 2 - 1 | North Carolina FC U23North Carolin |
| 12 May 22 | r02 | Caledonia SCCaledonia SC | 1 - 1 | Florida Elite Soccer AcadFlorida Elite |
| 12 May 22 | r02 | Blue Goose SCBlue Goose SC | 3 - 0 | Little Rock RangersLittle Rock R |
| 12 May 22 | r02 | AC Houston SurAC Houston Su | 0 - 2 | Round Rock SCRound Rock SC |
| 13 May 22 | r02 | LA Parish ACLA Parish AC | 1 - 4 | Texas UnitedTexas United |
| 13 May 22 | r02 | FC Miami CityFC Miami City | 1 - 2 | Nona FCNona FC |
| 14 May 22 | r02 | Kalamazoo FCKalamazoo FC | 1 - 0 | Oakland County FCOakland Count |
| 14 May 22 | r02 | Lansing City FootballLansing City | 2 - 3 | AFC Ann ArborAFC Ann Arbor |
| |
| 14 May 22 | r03 | Tormenta FC 2Tormenta FC 2 | 1 - 1 | Tennessee SCTennessee SC |
| 14 May 22 | r03 | San Francisco GlensSan Francisco | 2 - 0 | FC Golden State ForceFC Golden Sta |
| 14 May 22 | r03 | Southern California SeahoSouthern Cali | 2 - 0 | Central Valley Fuego IICentral Valle |
| 14 May 22 | r03 | Dayton Dutch LionsDayton Dutch | 0 - 5 | South Bend Lions FCSouth Bend Li |
| 15 May 22 | r03 | Virginia Beach United FCVirginia Beac | 0 - 3 | Lionsbridge FCLionsbridge F |
| 15 May 22 | r03 | Lehigh Valley UnitedLehigh Valley | 1 - 1 | Reading United ACReading Unite |
| 15 May 22 | r03 | Philadelphia Lone Star FCPhiladelphia | 1 - 5 | Real Central New JerseyReal Central |
| 15 May 22 | r03 | Wake FCWake FC | 1 - 6 | West Virginia UnitedWest Virginia |
| 15 May 22 | r03 | Caledonia SCCaledonia SC | 0 - 4 | Tampa Bay United SCTampa Bay Uni |
| 15 May 22 | r03 | Westchester FlamesWestchester F | 3 - 0 | Morris Elite SCMorris Elite |
| |
| 15 May 22 | r04 | North Carolina Fusion U23North Carolin | 7 - 2 | Tobacco Road FCTobacco Road |
| 15 May 22 | r04 | Dalton Red Wolves SCDalton Red Wo | 1 - 3 | Tri-Cities OttersTri-Cities Ot |
| 15 May 22 | r04 | Christos FCChristos FC | 3 - 2 | Northern Virginia FCNorthern Virg |
| 15 May 22 | r04 | One Knoxville SCOne Knoxville | 1 - 2 | Asheville City SCAsheville Cit |
| |
| 15 May 22 | r47 | Peoria CityPeoria City | 2 - 2 | Minneapolis CityMinneapolis C |
| |
| 15 May 22 | r04 | Louisiana Krewe FCLouisiana Kre | 2 - 2 | Texas UnitedTexas United |
| 15 May 22 | r04 | FC WichitaFC Wichita | 1 - 0 | Springfield ASCSpringfield A |
| 15 May 22 | r04 | Little Rock RangersLittle Rock R | 4 - 0 | LA Parish ACLA Parish AC |
| 15 May 22 | r04 | AC Houston SurAC Houston Su | 0 - 1 | Houston FCHouston FC |
| 15 May 22 | r04 | Des Moines MenaceDes Moines Me | 6 - 2 | St. Croix SCSt. Croix SC |
| |
| 15 May 22 | r05 | Fort Wayne FCFort Wayne FC | 1 - 2 | Kings Hammer FCKings Hammer |
| 15 May 22 | r05 | Project 51OProject 51O | 2 - 0 | San Francisco City FCSan Francisco |
| 15 May 22 | r05 | Boston City FCBoston City F | 0 - 4 | Vermont Green FCVermont Green |
| 16 May 22 | r05 | Charlotte Independence IICharlotte Ind | 1 - 2 | Charlotte EaglesCharlotte Eag |
| 16 May 22 | r05 | Patuxent Football AthletiPatuxent Foot | 0 - 0 | Commonwealth Cardinals FCCommonwealth |
| 16 May 22 | r05 | Central Valley Fuego IICentral Valle | 2 - 2 | FC Golden State ForceFC Golden Sta |
| 17 May 22 | r05 | Lehigh Valley UnitedLehigh Valley | 2 - 4 | West Chester United IIWest Chester |
| 18 May 22 | r05 | Dalton Red Wolves SCDalton Red Wo | 2 - 0 | Southern Soccer AcademySouthern Socc |
| 18 May 22 | r05 | Tormenta FC 2Tormenta FC 2 | 2 - 0 | East Atlanta FCEast Atlanta |
| 18 May 22 | r05 | One Knoxville SCOne Knoxville | 1 - 0 | Tri-Cities OttersTri-Cities Ot |
| |
| 19 May 22 | r06 | Charlotte Independence IICharlotte Ind | 0 - 0 | North Carolina FC U23North Carolin |
| 19 May 22 | r06 | Tampa Bay United SCTampa Bay Uni | 0 - 1 | The Villages SCThe Villages |
| 19 May 22 | r06 | Lansing City FootballLansing City | 0 - 4 | Kalamazoo FCKalamazoo FC |
| 19 May 22 | r06 | Florida Elite Soccer AcadFlorida Elite | 3 - 2 | Nona FCNona FC |
| 19 May 22 | r06 | West Chester United IIWest Chester | 1 - 3 | Reading United ACReading Unite |
| 19 May 22 | r06 | Houston FCHouston FC | 0 - 1 | Corpus Christi FCCorpus Christ |
| 20 May 22 | r06 | Tobacco Road FCTobacco Road | 4 - 2 | Wake FCWake FC |
| 20 May 22 | r06 | Asheville City SCAsheville Cit | 3 - 1 | Dalton Red Wolves SCDalton Red Wo |
| 20 May 22 | r06 | FC Miami CityFC Miami City | 0 - 3 | Miami ACMiami AC |
| 21 May 22 | r06 | Kings Hammer FCKings Hammer | 2 - 2 | Cleveland Force SCCleveland For |
| |
| 21 May 22 | r07 | Midwest United FCMidwest Unite | 0 - 2 | Kalamazoo FCKalamazoo FC |
| 21 May 22 | r07 | FC Málaga City New YorkFC Málaga Cit | 0 - 1 | Boston City FCBoston City F |
| 21 May 22 | r07 | Western Mass PioneersWestern Mass | 5 - 2 | Boston BoltsBoston Bolts |
| 21 May 22 | r07 | Minneapolis CityMinneapolis C | 0 - 1 | Peoria CityPeoria City |
| 21 May 22 | r07 | OVF AllianceOVF Alliance | 3 - 1 | PDX FCPDX FC |
| 21 May 22 | r07 | San Francisco City FCSan Francisco | 0 - 1 | Central Valley Fuego IICentral Valle |
| |
| 21 May 22 | r10 | AC ConnecticutAC Connecticu | 0 - 0 | Blackwatch RushBlackwatch Ru |
| 21 May 22 | r10 | Caledonia SCCaledonia SC | 0 - 0 | Weston FCWeston FC |
| |
| 21 May 22 | r07 | Kaw Valley FCKaw Valley FC | 1 - 3 | Saint LouisSaint Louis |
| 21 May 22 | r07 | South Bend Lions FCSouth Bend Li | 2 - 1 | Fort Wayne FCFort Wayne FC |
| |
| 21 May 22 | r71 | San Francisco GlensSan Francisco | 1 - 2 | Marin FC LegendsMarin FC Lege |
| |
| 22 May 22 | r08 | Reading United ACReading Unite | 2 - 2 | Philadelphia Lone Star FCPhiladelphia |
| 22 May 22 | r08 | Florida Elite Soccer AcadFlorida Elite | 3 - 0 | FC Florida U23FC Florida U2 |
| 22 May 22 | r08 | Wake FCWake FC | 0 - 6 | Charlotte Independence IICharlotte Ind |
| 22 May 22 | r08 | Lionsbridge FCLionsbridge F | 3 - 3 | Christos FCChristos FC |
| 22 May 22 | r08 | Tampa Bay United SCTampa Bay Uni | 2 - 3 | Nona FCNona FC |
| 22 May 22 | r08 | Virginia Beach United FCVirginia Beac | 2 - 1 | Commonwealth Cardinals FCCommonwealth |
| 22 May 22 | r08 | Hudson Valley HammersHudson Valley | 4 - 1 | New Jersey Copa FCNew Jersey Co |
| 22 May 22 | r08 | Flint City BucksFlint City Bu | 4 - 0 | Lansing City FootballLansing City |
| 22 May 22 | r08 | West Virginia UnitedWest Virginia | 6 - 0 | Charlotte EaglesCharlotte Eag |
| 22 May 22 | r08 | Real Central New JerseyReal Central | 1 - 1 | Ocean City NoreastersOcean City No |
| |
| 22 May 22 | r09 | East Atlanta FCEast Atlanta | 2 - 3 | Tri-Cities OttersTri-Cities Ot |
| 22 May 22 | r09 | Peachtree City MOBAPeachtree Cit | 0 - 2 | SC United BantamsSC United Ban |
| 22 May 22 | r09 | AHFC RoyalsAHFC Royals | 3 - 5 | Round Rock SCRound Rock SC |
| 22 May 22 | r09 | Houston FCHouston FC | 3 - 2 | Brazos Valley Cavalry FCBrazos Valley |
| 22 May 22 | r09 | FA Euro New YorkFA Euro New Y | 2 - 0 | Westchester FlamesWestchester F |
| 22 May 22 | r09 | Mississippi Brilla FCMississippi B | 3 - 1 | Little Rock RangersLittle Rock R |
| 22 May 22 | r09 | Springfield ASCSpringfield A | 1 - 0 | FC WichitaFC Wichita |
| 22 May 22 | r09 | Corpus Christi FCCorpus Christ | 2 - 0 | AC Houston SurAC Houston Su |
| 22 May 22 | r09 | Blue Goose SCBlue Goose SC | 0 - 1 | Texas UnitedTexas United |
| |
| 22 May 22 | r10 | Tennessee SCTennessee SC | 0 - 1 | One Knoxville SCOne Knoxville |
| 22 May 22 | r10 | Park City Red Wolves SCPark City Red | 2 - 1 | Ogden City SCOgden City SC |
| 22 May 22 | r10 | Ballard FCBallard FC | 5 - 1 | Lane United FCLane United F |
| 22 May 22 | r10 | FC Golden State ForceFC Golden Sta | 1 - 2 | Ventura County FusionVentura Count |
| 22 May 22 | r10 | Oly Town FCOly Town FC | 2 - 3 | Portland Timbers U23Portland Timb |
| 22 May 22 | r10 | Toledo Villa FCToledo Villa | 2 - 1 | Dayton Dutch LionsDayton Dutch |
| 22 May 22 | r10 | St. Croix SCSt. Croix SC | 1 - 2 | Peoria CityPeoria City |
| |
| 22 May 22 | r11 | Saint LouisSaint Louis | 2 - 1 | FC WichitaFC Wichita |
| 22 May 22 | r11 | North Carolina FC U23North Carolin | 1 - 2 | Tobacco Road FCTobacco Road |
| 22 May 22 | r11 | Seacoast United PhantomsSeacoast Unit | 1 - 0 | Vermont Green FCVermont Green |
| |
| 22 May 22 | r10 | Project 51OProject 51O | 4 - 1 | Central Valley Fuego IICentral Valle |
| |
| 23 May 22 | r41 | Long Island Rough RidersLong Island R | 5 - 0 | Morris Elite SCMorris Elite |
| |
| 23 May 22 | r11 | Cedar Stars RushCedar Stars R | 1 - 1 | FC Motown IIFC Motown II |
| 23 May 22 | r11 | Patuxent Football AthletiPatuxent Foot | 3 - 1 | Northern Virginia FCNorthern Virg |
| 23 May 22 | r11 | Chicago FC UnitedChicago FC Un | 3 - 3 | Chicago City SCChicago City |
| |
| 23 May 22 | r71 | LA Parish ACLA Parish AC | 2 - 9 | Louisiana Krewe FCLouisiana Kre |
| |
| 25 May 22 | r12 | Tormenta FC 2Tormenta FC 2 | 1 - 1 | Asheville City SCAsheville Cit |
| 25 May 22 | r12 | East Atlanta FCEast Atlanta | 1 - 4 | SC United BantamsSC United Ban |
| |
| 25 May 22 | r11 | Caledonia SCCaledonia SC | 0 - 3 | Nona FCNona FC |
| |
| 25 May 22 | r12 | West Chester United IIWest Chester | 3 - 2 | Real Central New JerseyReal Central |
| 25 May 22 | r12 | AFC Ann ArborAFC Ann Arbor | 1 - 2 | Kalamazoo FCKalamazoo FC |
| |
| 25 May 22 | r71 | Springfield ASCSpringfield A | 1 - 2 | Chicago Dutch Lions FCChicago Dutch |
| |
| 25 May 22 | r12 | FC Miami CityFC Miami City | 1 - 0 | Tampa Bay United SCTampa Bay Uni |
| |
| 25 May 22 | r14 | AC ConnecticutAC Connecticu | 2 - 4 | Black Rock FCBlack Rock FC |
| |
| 26 May 22 | r12 | Florida Elite Soccer AcadFlorida Elite | 1 - 1 | The Villages SCThe Villages |
| 26 May 22 | r12 | Wake FCWake FC | 2 - 3 | Charlotte EaglesCharlotte Eag |
| 26 May 22 | r12 | Toledo Villa FCToledo Villa | 0 - 5 | South Bend Lions FCSouth Bend Li |
| 26 May 22 | r12 | Charlotte Independence IICharlotte Ind | 5 - 1 | Tobacco Road FCTobacco Road |
| |
| 26 May 22 | r13 | West Virginia UnitedWest Virginia | 4 - 2 | North Carolina FC U23North Carolin |
| |
| 26 May 22 | r12 | Long Island Rough RidersLong Island R | 5 - 0 | Hudson Valley HammersHudson Valley |
| |
| 26 May 22 | r13 | Dalton Red Wolves SCDalton Red Wo | 3 - 2 | Peachtree City MOBAPeachtree Cit |
| 26 May 22 | r13 | Midwest United FCMidwest Unite | 0 - 3 | Flint City BucksFlint City Bu |
| 26 May 22 | r13 | FC Motown IIFC Motown II | 0 - 2 | Manhattan SCManhattan SC |
| 26 May 22 | r13 | Cedar Stars RushCedar Stars R | 0 - 0 | New Jersey Copa FCNew Jersey Co |
| 26 May 22 | r13 | AHFC RoyalsAHFC Royals | 1 - 1 | Corpus Christi FCCorpus Christ |
| 26 May 22 | r13 | Houston FCHouston FC | 2 - 2 | Round Rock SCRound Rock SC |
| 26 May 22 | r13 | Boston BoltsBoston Bolts | 0 - 2 | Boston City FCBoston City F |
| |
| 26 May 22 | r14 | Portland Timbers U23Portland Timb | 0 - 1 | PDX FCPDX FC |
| 26 May 22 | r14 | Southern California SeahoSouthern Cali | 2 - 2 | Ventura County FusionVentura Count |
| 26 May 22 | r14 | Davis Legacy SCDavis Legacy | 2 - 2 | San Francisco GlensSan Francisco |
| |
| 27 May 22 | r15 | Chicago Dutch Lions FCChicago Dutch | 1 - 4 | Chicago FC UnitedChicago FC Un |
| |
| 27 May 22 | r11 | West Chester United IIWest Chester | 2 - 0 | Lehigh Valley UnitedLehigh Valley |
| |
| 27 May 22 | r14 | Kaw Valley FCKaw Valley FC | 5 - 0 | FC WichitaFC Wichita |
| 27 May 22 | r14 | New Mexico United U-23New Mexico Un | 2 - 2 | Colorado ISAColorado ISA |
| 27 May 22 | r14 | Brazos Valley Cavalry FCBrazos Valley | 8 - 0 | AC Houston SurAC Houston Su |
| 27 May 22 | r14 | Park City Red Wolves SCPark City Red | 1 - 1 | Ogden City SCOgden City SC |
| |
| 28 May 22 | r15 | Seacoast United PhantomsSeacoast Unit | 4 - 0 | Western Mass PioneersWestern Mass |
| 28 May 22 | r15 | Ocean City NoreastersOcean City No | 2 - 1 | Philadelphia Lone Star FCPhiladelphia |
| 28 May 22 | r15 | Midwest United FCMidwest Unite | 1 - 0 | Lansing City FootballLansing City |
| 28 May 22 | r15 | Nona FCNona FC | 1 - 0 | Miami ACMiami AC |
| 28 May 22 | r15 | Real Central New JerseyReal Central | 0 - 0 | Reading United ACReading Unite |
| 28 May 22 | r15 | Peoria CityPeoria City | 2 - 4 | Des Moines MenaceDes Moines Me |
| |
| 28 May 22 | r18 | Texas UnitedTexas United | 2 - 2 | Mississippi Brilla FCMississippi B |
| |
| 28 May 22 | r31 | Morris Elite SCMorris Elite | 2 - 1 | FA Euro New YorkFA Euro New Y |
| |
| 28 May 22 | r15 | St. Croix SCSt. Croix SC | 1 - 0 | Minneapolis CityMinneapolis C |
| |
| 28 May 22 | r11 | Lane United FCLane United F | 1 - 2 | Portland Timbers U23Portland Timb |
| |
| 28 May 22 | r13 | Central Valley Fuego IICentral Valle | 0 - 3 | San Francisco City FCSan Francisco |
| |
| 28 May 22 | r15 | PDX FCPDX FC | 2 - 1 | Oly Town FCOly Town FC |
| |
| 28 May 22 | r16 | Toledo Villa FCToledo Villa | 1 - 3 | Fort Wayne FCFort Wayne FC |
| |
| 28 May 22 | r60 | Vermont Green FCVermont Green | 4 - 1 | Black Rock FCBlack Rock FC |
| |
| 28 May 22 | r16 | Saint LouisSaint Louis | 1 - 1 | Chicago City SCChicago City |
| 28 May 22 | r16 | Dayton Dutch LionsDayton Dutch | 3 - 3 | Cleveland Force SCCleveland For |
| |
| 28 May 22 | r17 | Charlotte EaglesCharlotte Eag | 3 - 1 | North Carolina FC U23North Carolin |
| |
| 29 May 22 | r16 | Wake FCWake FC | 4 - 0 | Tobacco Road FCTobacco Road |
| 29 May 22 | r16 | The Villages SCThe Villages | 2 - 0 | Weston FCWeston FC |
| 29 May 22 | r16 | West Virginia UnitedWest Virginia | 0 - 1 | North Carolina Fusion U23North Carolin |
| |
| 29 May 22 | r17 | South Bend Lions FCSouth Bend Li | 2 - 1 | Kings Hammer FCKings Hammer |
| 29 May 22 | r17 | Flint City BucksFlint City Bu | 1 - 1 | Kalamazoo FCKalamazoo FC |
| 29 May 22 | r17 | Florida Elite Soccer AcadFlorida Elite | 3 - 0 | Tampa Bay United SCTampa Bay Uni |
| |
| 29 May 22 | r07 | Oakland County FCOakland Count | 0 - 5 | AFC Ann ArborAFC Ann Arbor |
| |
| 29 May 22 | r16 | Virginia Beach United FCVirginia Beac | 2 - 1 | Patuxent Football AthletiPatuxent Foot |
| |
| 29 May 22 | r17 | FC Motown IIFC Motown II | 2 - 1 | Hudson Valley HammersHudson Valley |
| 29 May 22 | r17 | Commonwealth Cardinals FCCommonwealth | 1 - 4 | Lionsbridge FCLionsbridge F |
| |
| 29 May 22 | r50 | Caledonia SCCaledonia SC | 1 - 0 | FC Florida U23FC Florida U2 |
| |
| 29 May 22 | r17 | SC United BantamsSC United Ban | 1 - 2 | Peachtree City MOBAPeachtree Cit |
| 29 May 22 | r17 | Southern Soccer AcademySouthern Socc | 2 - 1 | East Atlanta FCEast Atlanta |
| 29 May 22 | r17 | Northern Virginia FCNorthern Virg | 1 - 3 | Christos FCChristos FC |
| |
| 29 May 22 | r18 | One Knoxville SCOne Knoxville | 4 - 1 | Dalton Red Wolves SCDalton Red Wo |
| |
| 29 May 22 | r16 | AHFC RoyalsAHFC Royals | 1 - 2 | Houston FCHouston FC |
| |
| 29 May 22 | r18 | Corpus Christi FCCorpus Christ | 2 - 4 | Round Rock SCRound Rock SC |
| 29 May 22 | r18 | Ogden City SCOgden City SC | 2 - 4 | Park City Red Wolves SCPark City Red |
| |
| 29 May 22 | r17 | AC Houston SurAC Houston Su | 0 - 3 | Brazos Valley Cavalry FCBrazos Valley |
| |
| 29 May 22 | r18 | Louisiana Krewe FCLouisiana Kre | 4 - 1 | Little Rock RangersLittle Rock R |
| 29 May 22 | r18 | Springfield ASCSpringfield A | 1 - 1 | Kaw Valley FCKaw Valley FC |
| 29 May 22 | r18 | Tennessee SCTennessee SC | 2 - 3 | Tri-Cities OttersTri-Cities Ot |
| |
| 29 May 22 | r19 | New Mexico United U-23New Mexico Un | 2 - 3 | Colorado Rush SCColorado Rush |
| |
| 29 May 22 | r18 | FC ManitobaFC Manitoba | 0 - 2 | Thunder Bay ChillThunder Bay C |
| |
| 29 May 22 | r13 | OVF AllianceOVF Alliance | 1 - 1 | Lane United FCLane United F |
| |
| 29 May 22 | r15 | Project 51OProject 51O | 0 - 1 | San Francisco GlensSan Francisco |
| |
| 30 May 22 | r19 | Cedar Stars RushCedar Stars R | 2 - 4 | Long Island Rough RidersLong Island R |
| 30 May 22 | r19 | Ocean City NoreastersOcean City No | 2 - 1 | West Chester United IIWest Chester |
| |
| 30 May 22 | r16 | Central Valley Fuego IICentral Valle | 0 - 1 | Ventura County FusionVentura Count |
| |
| 30 May 22 | r19 | Ballard FCBallard FC | 3 - 0 | Oly Town FCOly Town FC |
| 31 May 22 | r19 | Tormenta FC 2Tormenta FC 2 | 2 - 3 | One Knoxville SCOne Knoxville |
| 31 May 22 | r19 | Tennessee SCTennessee SC | 0 - 0 | Southern Soccer AcademySouthern Socc |
| |
| 31 May 22 | r39 | Black Rock FCBlack Rock FC | 1 - 3 | Western Mass PioneersWestern Mass |
| |
| 01 Jun 22 | r20 | Midwest United FCMidwest Unite | 0 - 1 | Flint City BucksFlint City Bu |
| 01 Jun 22 | r20 | Cleveland Force SCCleveland For | 2 - 1 | Fort Wayne FCFort Wayne FC |
| |
| 01 Jun 22 | r19 | FC Golden State ForceFC Golden Sta | 1 - 1 | Southern California SeahoSouthern Cali |
| |
| 01 Jun 22 | r22 | FC Florida U23FC Florida U2 | 1 - 3 | FC Miami CityFC Miami City |
| |
| 01 Jun 22 | r20 | New Jersey Copa FCNew Jersey Co | 2 - 1 | Cedar Stars RushCedar Stars R |
| 01 Jun 22 | r20 | Charlotte EaglesCharlotte Eag | 3 - 2 | Charlotte Independence IICharlotte Ind |
| 01 Jun 22 | r20 | Miami ACMiami AC | 3 - 0 | Florida Elite Soccer AcadFlorida Elite |
| 02 Jun 22 | r20 | Reading United ACReading Unite | 4 - 1 | Lehigh Valley UnitedLehigh Valley |
| 02 Jun 22 | r20 | Tri-Cities OttersTri-Cities Ot | 0 - 2 | Asheville City SCAsheville Cit |
| 02 Jun 22 | r20 | Virginia Beach United FCVirginia Beac | 0 - 1 | Lionsbridge FCLionsbridge F |
| |
| 02 Jun 22 | r21 | Seacoast United PhantomsSeacoast Unit | 3 - 1 | Boston BoltsBoston Bolts |
| |
| 02 Jun 22 | r20 | Nona FCNona FC | 2 - 1 | Tampa Bay United SCTampa Bay Uni |
| 02 Jun 22 | r20 | Christos FCChristos FC | 7 - 0 | Commonwealth Cardinals FCCommonwealth |
| |
| 02 Jun 22 | r22 | Caledonia SCCaledonia SC | 0 - 2 | The Villages SCThe Villages |
| |
| 02 Jun 22 | r21 | West Chester United IIWest Chester | 1 - 1 | Philadelphia Lone Star FCPhiladelphia |
| |
| 02 Jun 22 | r22 | North Carolina FC U23North Carolin | 2 - 2 | North Carolina Fusion U23North Carolin |
| |
| 02 Jun 22 | r19 | Houston FCHouston FC | 1 - 0 | AC Houston SurAC Houston Su |
| |
| 02 Jun 22 | r21 | Little Rock RangersLittle Rock R | 4 - 0 | Blue Goose SCBlue Goose SC |
| 02 Jun 22 | r21 | Chicago City SCChicago City | 1 - 0 | Springfield ASCSpringfield A |
| |
| 03 Jun 22 | r22 | Tormenta FC 2Tormenta FC 2 | 2 - 0 | Peachtree City MOBAPeachtree Cit |
| 03 Jun 22 | r22 | LA Parish ACLA Parish AC | 0 - 7 | Mississippi Brilla FCMississippi B |
| 03 Jun 22 | r22 | Colorado Rush SCColorado Rush | 4 - 1 | Colorado ISAColorado ISA |
| 04 Jun 22 | r22 | Oakland County FCOakland Count | 2 - 2 | Kalamazoo FCKalamazoo FC |
| |
| 04 Jun 22 | r23 | FC Málaga City New YorkFC Málaga Cit | 0 - 4 | AC ConnecticutAC Connecticu |
| 04 Jun 22 | r23 | Cleveland Force SCCleveland For | 2 - 2 | South Bend Lions FCSouth Bend Li |
| 04 Jun 22 | r23 | Thunder Bay ChillThunder Bay C | 0 - 3 | Des Moines MenaceDes Moines Me |
| |
| 04 Jun 22 | r21 | Peoria CityPeoria City | 1 - 1 | St. Croix SCSt. Croix SC |
| |
| 04 Jun 22 | r38 | Kaw Valley FCKaw Valley FC | 1 - 2 | Chicago FC UnitedChicago FC Un |
| |
| 04 Jun 22 | r21 | PDX FCPDX FC | 2 - 2 | Portland Timbers U23Portland Timb |
| |
| 04 Jun 22 | r23 | Ventura County FusionVentura Count | 0 - 0 | Southern California SeahoSouthern Cali |
| 04 Jun 22 | r23 | Toledo Villa FCToledo Villa | 1 - 2 | Kings Hammer FCKings Hammer |
| |
| 04 Jun 22 | r24 | Manhattan SCManhattan SC | 1 - 0 | FA Euro New YorkFA Euro New Y |
| 04 Jun 22 | r24 | Boston City FCBoston City F | 2 - 1 | Black Rock FCBlack Rock FC |
| |
| 04 Jun 22 | r26 | North Carolina FC U23North Carolin | 4 - 1 | Wake FCWake FC |
| |
| 04 Jun 22 | r23 | Vermont Green FCVermont Green | 1 - 2 | Seacoast United PhantomsSeacoast Unit |
| |
| 04 Jun 22 | r24 | San Francisco City FCSan Francisco | 1 - 4 | San Francisco GlensSan Francisco |
| 04 Jun 22 | r24 | Saint LouisSaint Louis | 7 - 2 | Chicago Dutch Lions FCChicago Dutch |
| 04 Jun 22 | r24 | Morris Elite SCMorris Elite | 0 - 2 | Hudson Valley HammersHudson Valley |
| |
| 05 Jun 22 | r25 | Reading United ACReading Unite | 0 - 2 | Ocean City NoreastersOcean City No |
| 05 Jun 22 | r25 | Dayton Dutch LionsDayton Dutch | 0 - 5 | Fort Wayne FCFort Wayne FC |
| 05 Jun 22 | r25 | West Virginia UnitedWest Virginia | 3 - 2 | Tobacco Road FCTobacco Road |
| 05 Jun 22 | r25 | Lionsbridge FCLionsbridge F | 5 - 1 | Northern Virginia FCNorthern Virg |
| 05 Jun 22 | r25 | The Villages SCThe Villages | 2 - 0 | FC Florida U23FC Florida U2 |
| |
| 05 Jun 22 | r65 | Lehigh Valley UnitedLehigh Valley | 1 - 3 | Philadelphia Lone Star FCPhiladelphia |
| |
| 05 Jun 22 | r24 | Commonwealth Cardinals FCCommonwealth | 1 - 2 | Virginia Beach United FCVirginia Beac |
| 05 Jun 22 | r24 | Florida Elite Soccer AcadFlorida Elite | 4 - 1 | Miami ACMiami AC |
| |
| 05 Jun 22 | r70 | Blackwatch RushBlackwatch Ru | 2 - 3 | Boston BoltsBoston Bolts |
| |
| 05 Jun 22 | r25 | Peachtree City MOBAPeachtree Cit | 0 - 6 | Asheville City SCAsheville Cit |
| 05 Jun 22 | r25 | North Carolina Fusion U23North Carolin | 3 - 1 | Charlotte EaglesCharlotte Eag |
| |
| 05 Jun 22 | r26 | SC United BantamsSC United Ban | 1 - 0 | Tri-Cities OttersTri-Cities Ot |
| 05 Jun 22 | r26 | Westchester FlamesWestchester F | 1 - 3 | Cedar Stars RushCedar Stars R |
| |
| 05 Jun 22 | r25 | Dalton Red Wolves SCDalton Red Wo | 1 - 1 | One Knoxville SCOne Knoxville |
| |
| 05 Jun 22 | r22 | Corpus Christi FCCorpus Christ | 3 - 0 | AHFC RoyalsAHFC Royals |
| 05 Jun 22 | r22 | Little Rock RangersLittle Rock R | 1 - 2 | Texas UnitedTexas United |
| |
| 05 Jun 22 | r23 | AC Houston SurAC Houston Su | 1 - 3 | Brazos Valley Cavalry FCBrazos Valley |
| |
| 05 Jun 22 | r26 | Mississippi Brilla FCMississippi B | 4 - 1 | Louisiana Krewe FCLouisiana Kre |
| |
| 05 Jun 22 | r23 | Tennessee SCTennessee SC | 2 - 0 | East Atlanta FCEast Atlanta |
| |
| 05 Jun 22 | r26 | Park City Red Wolves SCPark City Red | 2 - 0 | Colorado Rush SCColorado Rush |
| |
| 05 Jun 22 | r23 | Lane United FCLane United F | 2 - 0 | Oly Town FCOly Town FC |
| |
| 05 Jun 22 | r44 | FC WichitaFC Wichita | 3 - 4 | Chicago FC UnitedChicago FC Un |
| |
| 05 Jun 22 | r27 | Weston FCWeston FC | 1 - 1 | Nona FCNona FC |
| |
| 05 Jun 22 | r26 | Central Valley Fuego IICentral Valle | 0 - 6 | Davis Legacy SCDavis Legacy |
| 05 Jun 22 | r26 | Oakland County FCOakland Count | 4 - 2 | Midwest United FCMidwest Unite |
| 05 Jun 22 | r26 | Western Mass PioneersWestern Mass | 5 - 0 | FC Málaga City New YorkFC Málaga Cit |
| 05 Jun 22 | r26 | Long Island Rough RidersLong Island R | 3 - 1 | New Jersey Copa FCNew Jersey Co |
| |
| 05 Jun 22 | r24 | Portland Timbers U23Portland Timb | 3 - 1 | OVF AllianceOVF Alliance |
| |
| 05 Jun 22 | r27 | Project 51OProject 51O | 2 - 3 | Southern California SeahoSouthern Cali |
| |
| 06 Jun 22 | r24 | FC ManitobaFC Manitoba | 0 - 0 | Des Moines MenaceDes Moines Me |
| |
| 07 Jun 22 | r27 | Asheville City SCAsheville Cit | 2 - 1 | Tormenta FC 2Tormenta FC 2 |
| |
| 07 Jun 22 | r43 | Black Rock FCBlack Rock FC | 1 - 1 | Seacoast United PhantomsSeacoast Unit |
| |
| 08 Jun 22 | r27 | Dalton Red Wolves SCDalton Red Wo | 2 - 1 | SC United BantamsSC United Ban |
| 08 Jun 22 | r27 | Toledo Villa FCToledo Villa | 2 - 0 | Cleveland Force SCCleveland For |
| |
| 08 Jun 22 | r28 | Tri-Cities OttersTri-Cities Ot | 0 - 4 | One Knoxville SCOne Knoxville |
| 08 Jun 22 | r28 | North Carolina Fusion U23North Carolin | 5 - 0 | Wake FCWake FC |
| |
| 08 Jun 22 | r27 | Texas UnitedTexas United | 1 - 1 | Little Rock RangersLittle Rock R |
| |
| 08 Jun 22 | r28 | Round Rock SCRound Rock SC | 0 - 3 | Corpus Christi FCCorpus Christ |
| 08 Jun 22 | r28 | St. Croix SCSt. Croix SC | 3 - 3 | Minneapolis CityMinneapolis C |
| 08 Jun 22 | r28 | New Jersey Copa FCNew Jersey Co | 3 - 0 | FA Euro New YorkFA Euro New Y |
| |
| 08 Jun 22 | r29 | Weston FCWeston FC | 0 - 3 | Florida Elite Soccer AcadFlorida Elite |
| |
| 08 Jun 22 | r30 | AC ConnecticutAC Connecticu | 1 - 2 | Boston BoltsBoston Bolts |
| |
| 08 Jun 22 | r28 | Miami ACMiami AC | 2 - 1 | FC Florida U23FC Florida U2 |
| 09 Jun 22 | r28 | South Bend Lions FCSouth Bend Li | 2 - 0 | Dayton Dutch LionsDayton Dutch |
| |
| 09 Jun 22 | r29 | Ocean City NoreastersOcean City No | 2 - 1 | Lehigh Valley UnitedLehigh Valley |
| 09 Jun 22 | r29 | Charlotte Independence IICharlotte Ind | 5 - 0 | West Virginia UnitedWest Virginia |
| 09 Jun 22 | r29 | Charlotte EaglesCharlotte Eag | 5 - 0 | Tobacco Road FCTobacco Road |
| 09 Jun 22 | r29 | Tampa Bay United SCTampa Bay Uni | 3 - 0 | Caledonia SCCaledonia SC |
| 09 Jun 22 | r29 | Lionsbridge FCLionsbridge F | 1 - 0 | Patuxent Football AthletiPatuxent Foot |
| |
| 09 Jun 22 | r28 | Real Central New JerseyReal Central | 3 - 1 | Philadelphia Lone Star FCPhiladelphia |
| |
| 09 Jun 22 | r29 | Hudson Valley HammersHudson Valley | 3 - 1 | Manhattan SCManhattan SC |
| |
| 09 Jun 22 | r21 | Morris Elite SCMorris Elite | 1 - 4 | FC Motown IIFC Motown II |
| |
| 09 Jun 22 | r28 | Chicago City SCChicago City | 3 - 2 | Chicago Dutch Lions FCChicago Dutch |
| |
| 09 Jun 22 | r67 | Springfield ASCSpringfield A | 1 - 7 | Chicago FC UnitedChicago FC Un |
| |
| 10 Jun 22 | r30 | New Mexico United U-23New Mexico Un | 2 - 2 | Ogden City SCOgden City SC |
| 10 Jun 22 | r30 | Colorado Rush SCColorado Rush | 0 - 0 | Park City Red Wolves SCPark City Red |
| 11 Jun 22 | r30 | Flint City BucksFlint City Bu | 3 - 2 | Oakland County FCOakland Count |
| 11 Jun 22 | r30 | Dayton Dutch LionsDayton Dutch | 0 - 5 | Kings Hammer FCKings Hammer |
| |
| 11 Jun 22 | r29 | Thunder Bay ChillThunder Bay C | 1 - 1 | Peoria CityPeoria City |
| |
| 11 Jun 22 | r30 | Blackwatch RushBlackwatch Ru | 3 - 0 | Seacoast United PhantomsSeacoast Unit |
| 11 Jun 22 | r30 | Lansing City FootballLansing City | 1 - 0 | Kalamazoo FCKalamazoo FC |
| 11 Jun 22 | r30 | Midwest United FCMidwest Unite | 1 - 5 | AFC Ann ArborAFC Ann Arbor |
| |
| 11 Jun 22 | r31 | Western Mass PioneersWestern Mass | 3 - 0 | Boston City FCBoston City F |
| |
| 11 Jun 22 | r27 | Portland Timbers U23Portland Timb | 1 - 1 | Lane United FCLane United F |
| |
| 11 Jun 22 | r22 | Davis Legacy SCDavis Legacy | 2 - 2 | San Francisco City FCSan Francisco |
| |
| 11 Jun 22 | r27 | Ventura County FusionVentura Count | 1 - 4 | San Francisco GlensSan Francisco |
| |
| 11 Jun 22 | r31 | Ballard FCBallard FC | 1 - 0 | PDX FCPDX FC |
| |
| 11 Jun 22 | r34 | AC ConnecticutAC Connecticu | 4 - 1 | FC Málaga City New YorkFC Málaga Cit |
| |
| 11 Jun 22 | r31 | Colorado Rush SCColorado Rush | 0 - 3 | Park City Red Wolves SCPark City Red |
| |
| 11 Jun 22 | r53 | Saint LouisSaint Louis | 2 - 2 | Chicago FC UnitedChicago FC Un |
| |
| 11 Jun 22 | r31 | Boston BoltsBoston Bolts | 1 - 1 | Vermont Green FCVermont Green |
| 11 Jun 22 | r31 | Miami ACMiami AC | 0 - 1 | The Villages SCThe Villages |
| 12 Jun 22 | r31 | Charlotte Independence IICharlotte Ind | 3 - 4 | North Carolina Fusion U23North Carolin |
| |
| 12 Jun 22 | r32 | West Virginia UnitedWest Virginia | 4 - 1 | Wake FCWake FC |
| 12 Jun 22 | r32 | Fort Wayne FCFort Wayne FC | 1 - 2 | South Bend Lions FCSouth Bend Li |
| 12 Jun 22 | r32 | Philadelphia Lone Star FCPhiladelphia | 0 - 3 | Reading United ACReading Unite |
| 12 Jun 22 | r32 | Lehigh Valley UnitedLehigh Valley | 1 - 3 | Ocean City NoreastersOcean City No |
| 12 Jun 22 | r32 | Florida Elite Soccer AcadFlorida Elite | 3 - 0 | Caledonia SCCaledonia SC |
| 12 Jun 22 | r32 | Nona FCNona FC | 1 - 0 | FC Miami CityFC Miami City |
| 12 Jun 22 | r32 | Tri-Cities OttersTri-Cities Ot | 1 - 3 | Tennessee SCTennessee SC |
| 12 Jun 22 | r32 | Patuxent Football AthletiPatuxent Foot | 1 - 2 | Lionsbridge FCLionsbridge F |
| 12 Jun 22 | r32 | Cleveland Force SCCleveland For | 1 - 4 | Toledo Villa FCToledo Villa |
| |
| 12 Jun 22 | r33 | Commonwealth Cardinals FCCommonwealth | 0 - 2 | Northern Virginia FCNorthern Virg |
| 12 Jun 22 | r33 | Christos FCChristos FC | 6 - 0 | Virginia Beach United FCVirginia Beac |
| |
| 12 Jun 22 | r32 | Real Central New JerseyReal Central | 0 - 1 | West Chester United IIWest Chester |
| |
| 12 Jun 22 | r33 | Dalton Red Wolves SCDalton Red Wo | 1 - 2 | Tormenta FC 2Tormenta FC 2 |
| 12 Jun 22 | r33 | Asheville City SCAsheville Cit | 4 - 1 | East Atlanta FCEast Atlanta |
| 12 Jun 22 | r33 | Southern Soccer AcademySouthern Socc | 1 - 0 | Peachtree City MOBAPeachtree Cit |
| 12 Jun 22 | r33 | SC United BantamsSC United Ban | 1 - 3 | One Knoxville SCOne Knoxville |
| 12 Jun 22 | r33 | Westchester FlamesWestchester F | 1 - 4 | FC Motown IIFC Motown II |
| |
| 12 Jun 22 | r18 | FA Euro New YorkFA Euro New Y | 3 - 1 | Morris Elite SCMorris Elite |
| |
| 12 Jun 22 | r30 | Des Moines MenaceDes Moines Me | 4 - 1 | Minneapolis CityMinneapolis C |
| |
| 12 Jun 22 | r31 | Corpus Christi FCCorpus Christ | 2 - 1 | Houston FCHouston FC |
| |
| 12 Jun 22 | r34 | FC WichitaFC Wichita | 1 - 3 | Kaw Valley FCKaw Valley FC |
| |
| 12 Jun 22 | r33 | Texas UnitedTexas United | 5 - 1 | LA Parish ACLA Parish AC |
| 12 Jun 22 | r33 | Little Rock RangersLittle Rock R | 1 - 1 | Louisiana Krewe FCLouisiana Kre |
| |
| 12 Jun 22 | r34 | Blue Goose SCBlue Goose SC | 0 - 1 | Mississippi Brilla FCMississippi B |
| 12 Jun 22 | r34 | Brazos Valley Cavalry FCBrazos Valley | 2 - 1 | AHFC RoyalsAHFC Royals |
| |
| 12 Jun 22 | r31 | New Mexico United U-23New Mexico Un | 3 - 0 | Ogden City SCOgden City SC |
| |
| 12 Jun 22 | r21 | Weston FCWeston FC | 1 - 1 | Miami ACMiami AC |
| |
| 12 Jun 22 | r34 | FC ManitobaFC Manitoba | 1 - 4 | Peoria CityPeoria City |
| 12 Jun 22 | r34 | Manhattan SCManhattan SC | 5 - 4 | Hudson Valley HammersHudson Valley |
| 12 Jun 22 | r34 | Marin FC LegendsMarin FC Lege | 3 - 0 | FC Golden State ForceFC Golden Sta |
| 12 Jun 22 | r34 | Oakland County FCOakland Count | 4 - 2 | Lansing City FootballLansing City |
| 12 Jun 22 | r34 | Southern California SeahoSouthern Cali | 4 - 3 | Davis Legacy SCDavis Legacy |
| |
| 12 Jun 22 | r35 | PDX FCPDX FC | 0 - 7 | OVF AllianceOVF Alliance |
| 12 Jun 22 | r35 | Kalamazoo FCKalamazoo FC | 2 - 2 | Midwest United FCMidwest Unite |
| 12 Jun 22 | r35 | Oly Town FCOly Town FC | 1 - 1 | Ballard FCBallard FC |
| |
| 12 Jun 22 | r34 | Kaw Valley FCKaw Valley FC | 4 - 1 | Springfield ASCSpringfield A |
| |
| 13 Jun 22 | r35 | Long Island Rough RidersLong Island R | 3 - 2 | Cedar Stars RushCedar Stars R |
| 13 Jun 22 | r35 | Blackwatch RushBlackwatch Ru | 1 - 2 | Black Rock FCBlack Rock FC |
| 14 Jun 22 | r35 | FC Motown IIFC Motown II | 4 - 2 | New Jersey Copa FCNew Jersey Co |
| 14 Jun 22 | r35 | Miami ACMiami AC | 2 - 0 | FC Miami CityFC Miami City |
| |
| 14 Jun 22 | r38 | AC ConnecticutAC Connecticu | 2 - 5 | Seacoast United PhantomsSeacoast Unit |
| |
| 15 Jun 22 | r35 | Fort Wayne FCFort Wayne FC | 4 - 0 | Dayton Dutch LionsDayton Dutch |
| 15 Jun 22 | r35 | Toledo Villa FCToledo Villa | 2 - 3 | Kings Hammer FCKings Hammer |
| 15 Jun 22 | r35 | Philadelphia Lone Star FCPhiladelphia | 1 - 5 | West Chester United IIWest Chester |
| |
| 15 Jun 22 | r36 | Southern Soccer AcademySouthern Socc | 1 - 1 | Asheville City SCAsheville Cit |
| 15 Jun 22 | r36 | East Atlanta FCEast Atlanta | 3 - 2 | Peachtree City MOBAPeachtree Cit |
| |
| 15 Jun 22 | r58 | Black Rock FCBlack Rock FC | 4 - 1 | FC Málaga City New YorkFC Málaga Cit |
| |
| 15 Jun 22 | r36 | FC Miami CityFC Miami City | 3 - 2 | FC Florida U23FC Florida U2 |
| |
| 15 Jun 22 | r38 | North Carolina FC U23North Carolin | 3 - 0 | Wake FCWake FC |
| |
| 16 Jun 22 | r36 | The Villages SCThe Villages | 2 - 0 | Florida Elite Soccer AcadFlorida Elite |
| 16 Jun 22 | r36 | Tri-Cities OttersTri-Cities Ot | 0 - 3 | SC United BantamsSC United Ban |
| 16 Jun 22 | r36 | Charlotte EaglesCharlotte Eag | 1 - 3 | North Carolina Fusion U23North Carolin |
| |
| 16 Jun 22 | r37 | Lehigh Valley UnitedLehigh Valley | 3 - 2 | Real Central New JerseyReal Central |
| |
| 16 Jun 22 | r36 | Boston City FCBoston City F | 2 - 1 | Boston BoltsBoston Bolts |
| 16 Jun 22 | r36 | Cleveland Force SCCleveland For | 1 - 4 | Dayton Dutch LionsDayton Dutch |
| 16 Jun 22 | r36 | Chicago Dutch Lions FCChicago Dutch | 2 - 3 | Saint LouisSaint Louis |
| |
| 16 Jun 22 | r37 | Hudson Valley HammersHudson Valley | 2 - 0 | Westchester FlamesWestchester F |
| |
| 16 Jun 22 | r39 | Northern Virginia FCNorthern Virg | 2 - 2 | Lionsbridge FCLionsbridge F |
| |
| 16 Jun 22 | r37 | Western Mass PioneersWestern Mass | 0 - 1 | Blackwatch RushBlackwatch Ru |
| 16 Jun 22 | r37 | Long Island Rough RidersLong Island R | 0 - 1 | Manhattan SCManhattan SC |
| 16 Jun 22 | r37 | Houston FCHouston FC | 4 - 2 | AHFC RoyalsAHFC Royals |
| 16 Jun 22 | r37 | Morris Elite SCMorris Elite | 1 - 4 | Cedar Stars RushCedar Stars R |
| 16 Jun 22 | r37 | FA Euro New YorkFA Euro New Y | 1 - 1 | FC Motown IIFC Motown II |
| 16 Jun 22 | r37 | Patuxent Football AthletiPatuxent Foot | 3 - 2 | Christos FCChristos FC |
| 16 Jun 22 | r37 | LA Parish ACLA Parish AC | 4 - 4 | Blue Goose SCBlue Goose SC |
| |
| 17 Jun 22 | r21 | Chicago FC UnitedChicago FC Un | 1 - 2 | Kaw Valley FCKaw Valley FC |
| |
| 17 Jun 22 | r38 | Mississippi Brilla FCMississippi B | 0 - 1 | Texas UnitedTexas United |
| 17 Jun 22 | r38 | Chicago City SCChicago City | 3 - 0 | FC WichitaFC Wichita |
| 17 Jun 22 | r38 | Ogden City SCOgden City SC | 2 - 5 | New Mexico United U-23New Mexico Un |
| 17 Jun 22 | r38 | San Francisco City FCSan Francisco | 1 - 3 | Project 51OProject 51O |
| |
| 17 Jun 22 | r40 | Boston City FCBoston City F | 3 - 1 | AC ConnecticutAC Connecticu |
| |
| 18 Jun 22 | r38 | Kings Hammer FCKings Hammer | 2 - 1 | South Bend Lions FCSouth Bend Li |
| 18 Jun 22 | r38 | Tobacco Road FCTobacco Road | 1 - 2 | West Virginia UnitedWest Virginia |
| |
| 18 Jun 22 | r39 | Reading United ACReading Unite | 0 - 1 | Ocean City NoreastersOcean City No |
| 18 Jun 22 | r39 | Midwest United FCMidwest Unite | 0 - 2 | Oakland County FCOakland Count |
| 18 Jun 22 | r39 | Kalamazoo FCKalamazoo FC | 1 - 2 | Lansing City FootballLansing City |
| 18 Jun 22 | r39 | Thunder Bay ChillThunder Bay C | 3 - 1 | Minneapolis CityMinneapolis C |
| 18 Jun 22 | r39 | Real Central New JerseyReal Central | 5 - 4 | Philadelphia Lone Star FCPhiladelphia |
| |
| 18 Jun 22 | r19 | Western Mass PioneersWestern Mass | 2 - 1 | Black Rock FCBlack Rock FC |
| |
| 18 Jun 22 | r39 | AFC Ann ArborAFC Ann Arbor | 1 - 1 | Flint City BucksFlint City Bu |
| 18 Jun 22 | r39 | LA Parish ACLA Parish AC | 2 - 2 | Little Rock RangersLittle Rock R |
| |
| 18 Jun 22 | r43 | Colorado ISAColorado ISA | 1 - 1 | Colorado Rush SCColorado Rush |
| |
| 18 Jun 22 | r39 | Brazos Valley Cavalry FCBrazos Valley | 2 - 2 | Houston FCHouston FC |
| |
| 18 Jun 22 | r40 | Tennessee SCTennessee SC | 0 - 3 | Asheville City SCAsheville Cit |
| 18 Jun 22 | r40 | Portland Timbers U23Portland Timb | 1 - 0 | OVF AllianceOVF Alliance |
| 18 Jun 22 | r40 | Lane United FCLane United F | 2 - 2 | Ballard FCBallard FC |
| 18 Jun 22 | r40 | Southern California SeahoSouthern Cali | 2 - 1 | Marin FC LegendsMarin FC Lege |
| 18 Jun 22 | r40 | Davis Legacy SCDavis Legacy | 1 - 1 | FC Golden State ForceFC Golden Sta |
| |
| 18 Jun 22 | r41 | Weston FCWeston FC | 0 - 4 | FC Miami CityFC Miami City |
| |
| 18 Jun 22 | r40 | Manhattan SCManhattan SC | 3 - 1 | New Jersey Copa FCNew Jersey Co |
| |
| 18 Jun 22 | r43 | FC Florida U23FC Florida U2 | 1 - 1 | Florida Elite Soccer AcadFlorida Elite |
| |
| 18 Jun 22 | r41 | Tampa Bay United SCTampa Bay Uni | 1 - 0 | Miami ACMiami AC |
| |
| 18 Jun 22 | r40 | Vermont Green FCVermont Green | 2 - 0 | Boston BoltsBoston Bolts |
| 18 Jun 22 | r40 | San Francisco GlensSan Francisco | 1 - 1 | Project 51OProject 51O |
| 18 Jun 22 | r40 | Saint LouisSaint Louis | 4 - 1 | Springfield ASCSpringfield A |
| |
| 19 Jun 22 | r41 | Fort Wayne FCFort Wayne FC | 2 - 0 | Toledo Villa FCToledo Villa |
| 19 Jun 22 | r41 | Commonwealth Cardinals FCCommonwealth | 1 - 2 | Virginia Beach United FCVirginia Beac |
| 19 Jun 22 | r41 | The Villages SCThe Villages | 1 - 2 | Nona FCNona FC |
| |
| 19 Jun 22 | r55 | FC Málaga City New YorkFC Málaga Cit | 1 - 4 | Blackwatch RushBlackwatch Ru |
| |
| 19 Jun 22 | r41 | East Atlanta FCEast Atlanta | 1 - 3 | Southern Soccer AcademySouthern Socc |
| |
| 19 Jun 22 | r42 | SC United BantamsSC United Ban | 0 - 1 | Tormenta FC 2Tormenta FC 2 |
| |
| 19 Jun 22 | r41 | Westchester FlamesWestchester F | 2 - 2 | Hudson Valley HammersHudson Valley |
| |
| 19 Jun 22 | r42 | FC Motown IIFC Motown II | 2 - 3 | Long Island Rough RidersLong Island R |
| 19 Jun 22 | r42 | One Knoxville SCOne Knoxville | 3 - 0 | Peachtree City MOBAPeachtree Cit |
| 19 Jun 22 | r42 | Mississippi Brilla FCMississippi B | 0 - 1 | Texas UnitedTexas United |
| 19 Jun 22 | r42 | FA Euro New YorkFA Euro New Y | 2 - 2 | Cedar Stars RushCedar Stars R |
| |
| 19 Jun 22 | r41 | Chicago City SCChicago City | 5 - 3 | Kaw Valley FCKaw Valley FC |
| |
| 19 Jun 22 | r42 | St. Croix SCSt. Croix SC | 0 - 3 | Des Moines MenaceDes Moines Me |
| 19 Jun 22 | r42 | AC Houston SurAC Houston Su | 0 - 1 | Corpus Christi FCCorpus Christ |
| 19 Jun 22 | r42 | Louisiana Krewe FCLouisiana Kre | 2 - 1 | Blue Goose SCBlue Goose SC |
| |
| 19 Jun 22 | r43 | Chicago Dutch Lions FCChicago Dutch | 2 - 3 | FC WichitaFC Wichita |
| |
| 19 Jun 22 | r42 | Park City Red Wolves SCPark City Red | 3 - 1 | New Mexico United U-23New Mexico Un |
| 19 Jun 22 | r42 | Oly Town FCOly Town FC | 2 - 1 | PDX FCPDX FC |
| |
| 19 Jun 22 | r43 | AFC Ann ArborAFC Ann Arbor | 4 - 1 | Midwest United FCMidwest Unite |
| |
| 19 Jun 22 | r45 | Ventura County FusionVentura Count | 4 - 2 | Marin FC LegendsMarin FC Lege |
| |
| 19 Jun 22 | r27 | Chicago FC UnitedChicago FC Un | 5 - 1 | FC WichitaFC Wichita |
| |
| 19 Jun 22 | r43 | FC ManitobaFC Manitoba | 4 - 1 | Minneapolis CityMinneapolis C |
| |
| 19 Jun 22 | r67 | Manhattan SCManhattan SC | 3 - 2 | Morris Elite SCMorris Elite |
| |
| 19 Jun 22 | r43 | OVF AllianceOVF Alliance | 1 - 2 | Ballard FCBallard FC |
| |
| 19 Jun 22 | r51 | North Carolina FC U23North Carolin | 3 - 4 | Charlotte Independence IICharlotte Ind |
| |
| 19 Jun 22 | r43 | Patuxent Football AthletiPatuxent Foot | 2 - 3 | Northern Virginia FCNorthern Virg |
| |
| 19 Jun 22 | r44 | Chicago Dutch Lions FCChicago Dutch | 0 - 3 | Kaw Valley FCKaw Valley FC |
| |
| 20 Jun 22 | r27 | Seacoast United PhantomsSeacoast Unit | 2 - 1 | Black Rock FCBlack Rock FC |
| |
| 20 Jun 22 | r43 | Ocean City NoreastersOcean City No | 5 - 2 | Real Central New JerseyReal Central |
| 20 Jun 22 | r43 | AHFC RoyalsAHFC Royals | 5 - 1 | Round Rock SCRound Rock SC |
| |
| 20 Jun 22 | r38 | Colorado ISAColorado ISA | 0 - 3 | Park City Red Wolves SCPark City Red |
| |
| 21 Jun 22 | r44 | Lansing City FootballLansing City | 1 - 4 | Oakland County FCOakland Count |
| 22 Jun 22 | r44 | Charlotte EaglesCharlotte Eag | 6 - 1 | Wake FCWake FC |
| 22 Jun 22 | r44 | Toledo Villa FCToledo Villa | 3 - 1 | Cleveland Force SCCleveland For |
| 22 Jun 22 | r44 | SC United BantamsSC United Ban | 3 - 2 | East Atlanta FCEast Atlanta |
| 22 Jun 22 | r44 | North Carolina Fusion U23North Carolin | 2 - 0 | Charlotte Independence IICharlotte Ind |
| 22 Jun 22 | r44 | Asheville City SCAsheville Cit | 1 - 3 | One Knoxville SCOne Knoxville |
| 22 Jun 22 | r44 | West Chester United IIWest Chester | 5 - 0 | Reading United ACReading Unite |
| 22 Jun 22 | r44 | Boston City FCBoston City F | 3 - 2 | FC Málaga City New YorkFC Málaga Cit |
| |
| 22 Jun 22 | r45 | Commonwealth Cardinals FCCommonwealth | 2 - 0 | Patuxent Football AthletiPatuxent Foot |
| |
| 22 Jun 22 | r21 | Westchester FlamesWestchester F | 2 - 3 | Long Island Rough RidersLong Island R |
| |
| 22 Jun 22 | r45 | FC Golden State ForceFC Golden Sta | 1 - 1 | Southern California SeahoSouthern Cali |
| |
| 22 Jun 22 | r47 | FC Florida U23FC Florida U2 | 2 - 2 | The Villages SCThe Villages |
| |
| 22 Jun 22 | r24 | Weston FCWeston FC | 1 - 0 | Caledonia SCCaledonia SC |
| |
| 22 Jun 22 | r45 | Miami ACMiami AC | 0 - 2 | Nona FCNona FC |
| 22 Jun 22 | r45 | AC ConnecticutAC Connecticu | 4 - 6 | Vermont Green FCVermont Green |
| 23 Jun 22 | r45 | Kalamazoo FCKalamazoo FC | 1 - 0 | Flint City BucksFlint City Bu |
| 23 Jun 22 | r45 | Florida Elite Soccer AcadFlorida Elite | 2 - 3 | FC Miami CityFC Miami City |
| 23 Jun 22 | r45 | Peachtree City MOBAPeachtree Cit | 2 - 1 | Dalton Red Wolves SCDalton Red Wo |
| 23 Jun 22 | r45 | Black Rock FCBlack Rock FC | 2 - 0 | Boston BoltsBoston Bolts |
| 23 Jun 22 | r45 | Southern Soccer AcademySouthern Socc | 1 - 2 | Tormenta FC 2Tormenta FC 2 |
| |
| 23 Jun 22 | r46 | FA Euro New YorkFA Euro New Y | 0 - 1 | Manhattan SCManhattan SC |
| 23 Jun 22 | r46 | Round Rock SCRound Rock SC | 0 - 0 | AHFC RoyalsAHFC Royals |
| 23 Jun 22 | r46 | Morris Elite SCMorris Elite | 0 - 3 | New Jersey Copa FCNew Jersey Co |
| 23 Jun 22 | r46 | Peoria CityPeoria City | 1 - 4 | Des Moines MenaceDes Moines Me |
| 23 Jun 22 | r46 | Springfield ASCSpringfield A | 1 - 4 | Saint LouisSaint Louis |
| 23 Jun 22 | r46 | Houston FCHouston FC | 1 - 0 | AC Houston SurAC Houston Su |
| 23 Jun 22 | r46 | Little Rock RangersLittle Rock R | 0 - 3 | Blue Goose SCBlue Goose SC |
| 23 Jun 22 | r46 | FC ManitobaFC Manitoba | 1 - 2 | St. Croix SCSt. Croix SC |
| 23 Jun 22 | r46 | Mississippi Brilla FCMississippi B | 7 - 0 | LA Parish ACLA Parish AC |
| |
| 23 Jun 22 | r47 | Chicago FC UnitedChicago FC Un | 8 - 0 | Chicago Dutch Lions FCChicago Dutch |
| |
| 23 Jun 22 | r46 | Brazos Valley Cavalry FCBrazos Valley | 4 - 1 | Corpus Christi FCCorpus Christ |
| |
| 23 Jun 22 | r31 | San Francisco City FCSan Francisco | 3 - 3 | Davis Legacy SCDavis Legacy |
| |
| 24 Jun 22 | r47 | Tobacco Road FCTobacco Road | 0 - 5 | North Carolina FC U23North Carolin |
| 24 Jun 22 | r47 | Colorado ISAColorado ISA | 3 - 4 | Ogden City SCOgden City SC |
| 24 Jun 22 | r47 | Texas UnitedTexas United | 1 - 1 | Louisiana Krewe FCLouisiana Kre |
| 24 Jun 22 | r47 | Lane United FCLane United F | 4 - 1 | PDX FCPDX FC |
| 24 Jun 22 | r47 | FC Málaga City New YorkFC Málaga Cit | 1 - 6 | Seacoast United PhantomsSeacoast Unit |
| |
| 25 Jun 22 | r48 | Charlotte EaglesCharlotte Eag | 1 - 1 | West Virginia UnitedWest Virginia |
| 25 Jun 22 | r48 | Ocean City NoreastersOcean City No | 1 - 1 | Reading United ACReading Unite |
| |
| 25 Jun 22 | r47 | Oakland County FCOakland Count | 1 - 3 | AFC Ann ArborAFC Ann Arbor |
| |
| 25 Jun 22 | r48 | Thunder Bay ChillThunder Bay C | 3 - 1 | St. Croix SCSt. Croix SC |
| 25 Jun 22 | r48 | Real Central New JerseyReal Central | 3 - 2 | Lehigh Valley UnitedLehigh Valley |
| 25 Jun 22 | r48 | North Carolina Fusion U23North Carolin | 3 - 0 | Charlotte Independence IICharlotte Ind |
| 25 Jun 22 | r48 | FC WichitaFC Wichita | 3 - 1 | Chicago City SCChicago City |
| 25 Jun 22 | r48 | Portland Timbers U23Portland Timb | 3 - 1 | Oly Town FCOly Town FC |
| 25 Jun 22 | r48 | Ballard FCBallard FC | 2 - 0 | OVF AllianceOVF Alliance |
| |
| 25 Jun 22 | r73 | Marin FC LegendsMarin FC Lege | 1 - 3 | Davis Legacy SCDavis Legacy |
| |
| 25 Jun 22 | r18 | FC Florida U23FC Florida U2 | 3 - 0 | Caledonia SCCaledonia SC |
| |
| 25 Jun 22 | r49 | New Jersey Copa FCNew Jersey Co | 2 - 1 | Long Island Rough RidersLong Island R |
| 25 Jun 22 | r49 | South Bend Lions FCSouth Bend Li | 2 - 1 | Cleveland Force SCCleveland For |
| |
| 25 Jun 22 | r73 | Boston City FCBoston City F | 5 - 1 | Blackwatch RushBlackwatch Ru |
| |
| 25 Jun 22 | r49 | Western Mass PioneersWestern Mass | 3 - 2 | Vermont Green FCVermont Green |
| |
| 26 Jun 22 | r04 | Minneapolis CityMinneapolis C | 0 - 2 | Peoria CityPeoria City |
| |
| 26 Jun 22 | r49 | Kings Hammer FCKings Hammer | 1 - 1 | Fort Wayne FCFort Wayne FC |
| |
| 26 Jun 22 | r50 | The Villages SCThe Villages | 1 - 1 | Tampa Bay United SCTampa Bay Uni |
| 26 Jun 22 | r50 | Philadelphia Lone Star FCPhiladelphia | 3 - 1 | Lehigh Valley UnitedLehigh Valley |
| |
| 26 Jun 22 | r49 | Commonwealth Cardinals FCCommonwealth | 2 - 5 | Christos FCChristos FC |
| 26 Jun 22 | r49 | Nona FCNona FC | 3 - 1 | Florida Elite Soccer AcadFlorida Elite |
| |
| 26 Jun 22 | r50 | Southern Soccer AcademySouthern Socc | 0 - 2 | Dalton Red Wolves SCDalton Red Wo |
| 26 Jun 22 | r50 | Westchester FlamesWestchester F | 0 - 2 | FA Euro New YorkFA Euro New Y |
| 26 Jun 22 | r50 | Flint City BucksFlint City Bu | 1 - 2 | Lansing City FootballLansing City |
| 26 Jun 22 | r50 | One Knoxville SCOne Knoxville | 1 - 0 | Tennessee SCTennessee SC |
| |
| 26 Jun 22 | r51 | Corpus Christi FCCorpus Christ | 1 - 4 | Brazos Valley Cavalry FCBrazos Valley |
| |
| 26 Jun 22 | r14 | LA Parish ACLA Parish AC | 0 - 5 | Little Rock RangersLittle Rock R |
| |
| 26 Jun 22 | r50 | Des Moines MenaceDes Moines Me | 3 - 0 | FC ManitobaFC Manitoba |
| 26 Jun 22 | r50 | Texas UnitedTexas United | 3 - 1 | Blue Goose SCBlue Goose SC |
| |
| 26 Jun 22 | r51 | Louisiana Krewe FCLouisiana Kre | 3 - 1 | Mississippi Brilla FCMississippi B |
| 26 Jun 22 | r51 | AHFC RoyalsAHFC Royals | 2 - 1 | AC Houston SurAC Houston Su |
| 26 Jun 22 | r51 | Chicago Dutch Lions FCChicago Dutch | 1 - 7 | Chicago FC UnitedChicago FC Un |
| |
| 26 Jun 22 | r49 | Colorado ISAColorado ISA | 2 - 3 | Park City Red Wolves SCPark City Red |
| |
| 26 Jun 22 | r51 | Kaw Valley FCKaw Valley FC | 2 - 0 | Chicago City SCChicago City |
| |
| 26 Jun 22 | r49 | Colorado Rush SCColorado Rush | 2 - 1 | Ogden City SCOgden City SC |
| |
| 26 Jun 22 | r48 | Ventura County FusionVentura Count | 1 - 0 | Central Valley Fuego IICentral Valle |
| |
| 26 Jun 22 | r51 | Charlotte Independence IICharlotte Ind | 6 - 2 | Wake FCWake FC |
| 26 Jun 22 | r51 | Black Rock FCBlack Rock FC | 2 - 0 | AC ConnecticutAC Connecticu |
| 26 Jun 22 | r51 | San Francisco GlensSan Francisco | 0 - 1 | Southern California SeahoSouthern Cali |
| |
| 26 Jun 22 | r47 | Oly Town FCOly Town FC | 6 - 5 | OVF AllianceOVF Alliance |
| |
| 26 Jun 22 | r51 | PDX FCPDX FC | 1 - 2 | Ballard FCBallard FC |
| |
| 26 Jun 22 | r52 | Kalamazoo FCKalamazoo FC | 4 - 1 | AFC Ann ArborAFC Ann Arbor |
| 26 Jun 22 | r52 | Project 51OProject 51O | 2 - 1 | Marin FC LegendsMarin FC Lege |
| 26 Jun 22 | r52 | Miami ACMiami AC | 2 - 1 | Caledonia SCCaledonia SC |
| 27 Jun 22 | r52 | Hudson Valley HammersHudson Valley | 3 - 4 | Cedar Stars RushCedar Stars R |
| 27 Jun 22 | r52 | East Atlanta FCEast Atlanta | 1 - 3 | Tormenta FC 2Tormenta FC 2 |
| 28 Jun 22 | r52 | Davis Legacy SCDavis Legacy | 3 - 2 | Southern California SeahoSouthern Cali |
| |
| 28 Jun 22 | r68 | Seacoast United PhantomsSeacoast Unit | 1 - 0 | Boston City FCBoston City F |
| |
| 29 Jun 22 | r52 | Cleveland Force SCCleveland For | 0 - 3 | Kings Hammer FCKings Hammer |
| |
| 29 Jun 22 | r68 | Vermont Green FCVermont Green | 3 - 0 | Blackwatch RushBlackwatch Ru |
| |
| 29 Jun 22 | r53 | Houston FCHouston FC | 2 - 0 | Brazos Valley Cavalry FCBrazos Valley |
| |
| 29 Jun 22 | r33 | Round Rock SCRound Rock SC | 4 - 2 | AC Houston SurAC Houston Su |
| |
| 29 Jun 22 | r52 | Blue Goose SCBlue Goose SC | 2 - 3 | LA Parish ACLA Parish AC |
| |
| 29 Jun 22 | r53 | St. Croix SCSt. Croix SC | 2 - 4 | FC ManitobaFC Manitoba |
| 29 Jun 22 | r53 | Tennessee SCTennessee SC | 2 - 1 | Peachtree City MOBAPeachtree Cit |
| |
| 29 Jun 22 | r29 | Chicago FC UnitedChicago FC Un | 2 - 0 | Saint LouisSaint Louis |
| |
| 29 Jun 22 | r53 | New Jersey Copa FCNew Jersey Co | 2 - 5 | Hudson Valley HammersHudson Valley |
| 30 Jun 22 | r53 | South Bend Lions FCSouth Bend Li | 3 - 0 | Toledo Villa FCToledo Villa |
| 30 Jun 22 | r53 | Tobacco Road FCTobacco Road | 3 - 3 | Charlotte Independence IICharlotte Ind |
| 30 Jun 22 | r53 | Tampa Bay United SCTampa Bay Uni | - | Florida Elite Soccer AcadFlorida Elite |
| 30 Jun 22 | r53 | Cedar Stars RushCedar Stars R | 4 - 2 | Westchester FlamesWestchester F |
| |
| 30 Jun 22 | r75 | North Carolina Fusion U23North Carolin | 2 - 2 | West Virginia UnitedWest Virginia |
| |
| 30 Jun 22 | r53 | FC Motown IIFC Motown II | 5 - 0 | Morris Elite SCMorris Elite |
| |
| 30 Jun 22 | r54 | Nona FCNona FC | 3 - 0 | FC Florida U23FC Florida U2 |
| 30 Jun 22 | r54 | Christos FCChristos FC | 0 - 3 | Lionsbridge FCLionsbridge F |
| 30 Jun 22 | r54 | Real Central New JerseyReal Central | 2 - 3 | Reading United ACReading Unite |
| 30 Jun 22 | r54 | Boston BoltsBoston Bolts | 0 - 1 | AC ConnecticutAC Connecticu |
| 30 Jun 22 | r54 | Tormenta FC 2Tormenta FC 2 | 4 - 0 | Southern Soccer AcademySouthern Socc |
| 30 Jun 22 | r54 | AFC Ann ArborAFC Ann Arbor | 1 - 1 | Flint City BucksFlint City Bu |
| 30 Jun 22 | r54 | West Chester United IIWest Chester | 1 - 2 | Ocean City NoreastersOcean City No |
| |
| 30 Jun 22 | r55 | AHFC RoyalsAHFC Royals | 2 - 1 | Corpus Christi FCCorpus Christ |
| 30 Jun 22 | r55 | FA Euro New YorkFA Euro New Y | 0 - 0 | Long Island Rough RidersLong Island R |
| |
| 30 Jun 22 | r54 | Chicago Dutch Lions FCChicago Dutch | 3 - 5 | Chicago City SCChicago City |
| |
| 30 Jun 22 | r55 | Minneapolis CityMinneapolis C | 1 - 2 | FC ManitobaFC Manitoba |
| 30 Jun 22 | r55 | Louisiana Krewe FCLouisiana Kre | 1 - 2 | Texas UnitedTexas United |
| |
| 30 Jun 22 | r52 | San Francisco City FCSan Francisco | 0 - 1 | Marin FC LegendsMarin FC Lege |
| |
| 01 Jul 22 | r41 | Blackwatch RushBlackwatch Ru | 2 - 0 | FC Málaga City New YorkFC Málaga Cit |
| |
| 01 Jul 22 | r55 | Blue Goose SCBlue Goose SC | 6 - 5 | LA Parish ACLA Parish AC |
| 01 Jul 22 | r55 | New Mexico United U-23New Mexico Un | 2 - 0 | Park City Red Wolves SCPark City Red |
| 01 Jul 22 | r55 | Ogden City SCOgden City SC | 1 - 0 | Colorado ISAColorado ISA |
| 01 Jul 22 | r55 | Lane United FCLane United F | 0 - 0 | OVF AllianceOVF Alliance |
| |
| 02 Jul 22 | r56 | Kings Hammer FCKings Hammer | 5 - 1 | Toledo Villa FCToledo Villa |
| 02 Jul 22 | r56 | Ocean City NoreastersOcean City No | 1 - 0 | Real Central New JerseyReal Central |
| 02 Jul 22 | r56 | FC Motown IIFC Motown II | 1 - 2 | Cedar Stars RushCedar Stars R |
| 02 Jul 22 | r56 | Patuxent Football AthletiPatuxent Foot | 1 - 2 | Virginia Beach United FCVirginia Beac |
| 02 Jul 22 | r56 | Western Mass PioneersWestern Mass | 3 - 1 | Seacoast United PhantomsSeacoast Unit |
| 02 Jul 22 | r56 | Round Rock SCRound Rock SC | 1 - 1 | Houston FCHouston FC |
| 02 Jul 22 | r56 | Des Moines MenaceDes Moines Me | 2 - 2 | Thunder Bay ChillThunder Bay C |
| 02 Jul 22 | r56 | Peoria CityPeoria City | 3 - 2 | FC ManitobaFC Manitoba |
| |
| 02 Jul 22 | r57 | Chicago FC UnitedChicago FC Un | 1 - 0 | Chicago City SCChicago City |
| |
| 02 Jul 22 | r55 | Southern California SeahoSouthern Cali | 1 - 1 | FC Golden State ForceFC Golden Sta |
| |
| 02 Jul 22 | r57 | Ventura County FusionVentura Count | 2 - 3 | Project 51OProject 51O |
| 02 Jul 22 | r57 | Ballard FCBallard FC | 0 - 2 | Portland Timbers U23Portland Timb |
| 02 Jul 22 | r57 | Tobacco Road FCTobacco Road | 1 - 5 | North Carolina Fusion U23North Carolin |
| 02 Jul 22 | r57 | Vermont Green FCVermont Green | 3 - 1 | Boston City FCBoston City F |
| |
| 02 Jul 22 | r14 | FC Florida U23FC Florida U2 | 0 - 1 | Weston FCWeston FC |
| |
| 02 Jul 22 | r56 | San Francisco GlensSan Francisco | 3 - 0 | Davis Legacy SCDavis Legacy |
| |
| 02 Jul 22 | r57 | Morris Elite SCMorris Elite | 0 - 1 | Long Island Rough RidersLong Island R |
| |
| 03 Jul 22 | r36 | FC Málaga City New YorkFC Málaga Cit | 2 - 1 | Black Rock FCBlack Rock FC |
| |
| 03 Jul 22 | r56 | West Virginia UnitedWest Virginia | 3 - 2 | Charlotte Independence IICharlotte Ind |
| |
| 03 Jul 22 | r57 | Oakland County FCOakland Count | 2 - 5 | Flint City BucksFlint City Bu |
| |
| 03 Jul 22 | r58 | Fort Wayne FCFort Wayne FC | 2 - 2 | South Bend Lions FCSouth Bend Li |
| 03 Jul 22 | r58 | FC Miami CityFC Miami City | 2 - 3 | The Villages SCThe Villages |
| 03 Jul 22 | r58 | Tri-Cities OttersTri-Cities Ot | 1 - 0 | Tormenta FC 2Tormenta FC 2 |
| |
| 03 Jul 22 | r57 | Reading United ACReading Unite | 1 - 1 | West Chester United IIWest Chester |
| |
| 03 Jul 22 | r58 | Peachtree City MOBAPeachtree Cit | 3 - 0 | Southern Soccer AcademySouthern Socc |
| 03 Jul 22 | r58 | Westchester FlamesWestchester F | 1 - 2 | Manhattan SCManhattan SC |
| 03 Jul 22 | r58 | AFC Ann ArborAFC Ann Arbor | 1 - 1 | Lansing City FootballLansing City |
| 03 Jul 22 | r58 | Northern Virginia FCNorthern Virg | 1 - 2 | Commonwealth Cardinals FCCommonwealth |
| 03 Jul 22 | r58 | SC United BantamsSC United Ban | 1 - 1 | Tennessee SCTennessee SC |
| 03 Jul 22 | r58 | East Atlanta FCEast Atlanta | 0 - 2 | One Knoxville SCOne Knoxville |
| |
| 03 Jul 22 | r59 | Little Rock RangersLittle Rock R | 2 - 1 | Mississippi Brilla FCMississippi B |
| 03 Jul 22 | r59 | FA Euro New YorkFA Euro New Y | 2 - 0 | New Jersey Copa FCNew Jersey Co |
| 03 Jul 22 | r59 | Blue Goose SCBlue Goose SC | 2 - 3 | Louisiana Krewe FCLouisiana Kre |
| 03 Jul 22 | r59 | Corpus Christi FCCorpus Christ | 2 - 3 | AC Houston SurAC Houston Su |
| |
| 03 Jul 22 | r57 | New Mexico United U-23New Mexico Un | 1 - 2 | Park City Red Wolves SCPark City Red |
| |
| 03 Jul 22 | r59 | Ogden City SCOgden City SC | 3 - 1 | Colorado ISAColorado ISA |
| |
| 03 Jul 22 | r57 | Oly Town FCOly Town FC | 1 - 1 | Lane United FCLane United F |
| |
| 03 Jul 22 | r59 | FC WichitaFC Wichita | 3 - 1 | Saint LouisSaint Louis |
| 04 Jul 22 | r59 | Lionsbridge FCLionsbridge F | 2 - 1 | Virginia Beach United FCVirginia Beac |
| 04 Jul 22 | r59 | Chicago City SCChicago City | 4 - 2 | Springfield ASCSpringfield A |
| |
| 04 Jul 22 | r60 | AHFC RoyalsAHFC Royals | 1 - 4 | Brazos Valley Cavalry FCBrazos Valley |
| 04 Jul 22 | r60 | Peoria CityPeoria City | 3 - 0 | Thunder Bay ChillThunder Bay C |
| 04 Jul 22 | r60 | FC Golden State ForceFC Golden Sta | 1 - 2 | Project 51OProject 51O |
| 05 Jul 22 | r60 | Weston FCWeston FC | 3 - 1 | Tampa Bay United SCTampa Bay Uni |
| 06 Jul 22 | r60 | FC Málaga City New YorkFC Málaga Cit | 0 - 3 | Western Mass PioneersWestern Mass |
| 06 Jul 22 | r60 | Flint City BucksFlint City Bu | 1 - 3 | Oakland County FCOakland Count |
| 06 Jul 22 | r60 | St. Croix SCSt. Croix SC | 1 - 2 | Thunder Bay ChillThunder Bay C |
| |
| 06 Jul 22 | r62 | FC Florida U23FC Florida U2 | 1 - 2 | Miami ACMiami AC |
| |
| 06 Jul 22 | r16 | Black Rock FCBlack Rock FC | 1 - 0 | Vermont Green FCVermont Green |
| |
| 06 Jul 22 | r60 | North Carolina FC U23North Carolin | 1 - 2 | West Virginia UnitedWest Virginia |
| |
| 06 Jul 22 | r61 | FC Miami CityFC Miami City | 7 - 1 | Caledonia SCCaledonia SC |
| 06 Jul 22 | r61 | FC Motown IIFC Motown II | 2 - 2 | Westchester FlamesWestchester F |
| 07 Jul 22 | r61 | Philadelphia Lone Star FCPhiladelphia | 0 - 0 | Ocean City NoreastersOcean City No |
| 07 Jul 22 | r61 | Boston BoltsBoston Bolts | 2 - 3 | Seacoast United PhantomsSeacoast Unit |
| 07 Jul 22 | r61 | Fort Wayne FCFort Wayne FC | 3 - 0 | Toledo Villa FCToledo Villa |
| |
| 07 Jul 22 | r62 | Charlotte Independence IICharlotte Ind | 2 - 6 | Charlotte EaglesCharlotte Eag |
| 07 Jul 22 | r62 | Tri-Cities OttersTri-Cities Ot | 2 - 0 | Southern Soccer AcademySouthern Socc |
| |
| 07 Jul 22 | r23 | Lansing City FootballLansing City | 1 - 0 | Midwest United FCMidwest Unite |
| |
| 07 Jul 22 | r61 | Cedar Stars RushCedar Stars R | 3 - 5 | Hudson Valley HammersHudson Valley |
| 07 Jul 22 | r61 | Lionsbridge FCLionsbridge F | 2 - 1 | Christos FCChristos FC |
| 07 Jul 22 | r61 | Lehigh Valley UnitedLehigh Valley | 0 - 6 | West Chester United IIWest Chester |
| |
| 07 Jul 22 | r62 | Cleveland Force SCCleveland For | 0 - 2 | South Bend Lions FCSouth Bend Li |
| |
| 07 Jul 22 | r61 | Manhattan SCManhattan SC | 1 - 2 | Long Island Rough RidersLong Island R |
| |
| 07 Jul 22 | r62 | Northern Virginia FCNorthern Virg | 5 - 0 | Virginia Beach United FCVirginia Beac |
| 07 Jul 22 | r62 | Asheville City SCAsheville Cit | 7 - 1 | SC United BantamsSC United Ban |
| 07 Jul 22 | r62 | Blackwatch RushBlackwatch Ru | 1 - 6 | AC ConnecticutAC Connecticu |
| |
| 07 Jul 22 | r60 | Minneapolis CityMinneapolis C | 1 - 2 | Thunder Bay ChillThunder Bay C |
| |
| 07 Jul 22 | r61 | Colorado ISAColorado ISA | 0 - 1 | New Mexico United U-23New Mexico Un |
| |
| 07 Jul 22 | r62 | Springfield ASCSpringfield A | 1 - 3 | Chicago Dutch Lions FCChicago Dutch |
| |
| 07 Jul 22 | r63 | Chicago City SCChicago City | 2 - 4 | Chicago FC UnitedChicago FC Un |
| |
| 07 Jul 22 | r62 | Davis Legacy SCDavis Legacy | 1 - 2 | Ventura County FusionVentura Count |
| |
| 07 Jul 22 | r37 | Tampa Bay United SCTampa Bay Uni | 0 - 1 | Weston FCWeston FC |
| |
| 08 Jul 22 | r63 | Dayton Dutch LionsDayton Dutch | 1 - 7 | Kings Hammer FCKings Hammer |
| |
| 08 Jul 22 | r59 | Texas UnitedTexas United | 5 - 0 | Blue Goose SCBlue Goose SC |
| |
| 08 Jul 22 | r62 | LA Parish ACLA Parish AC | 0 - 2 | Mississippi Brilla FCMississippi B |
| |
| 08 Jul 22 | r63 | Brazos Valley Cavalry FCBrazos Valley | 2 - 1 | Round Rock SCRound Rock SC |
| 08 Jul 22 | r63 | Lane United FCLane United F | 2 - 2 | Portland Timbers U23Portland Timb |
| 08 Jul 22 | r63 | Oly Town FCOly Town FC | 0 - 1 | Ballard FCBallard FC |
| 08 Jul 22 | r63 | Black Rock FCBlack Rock FC | 1 - 2 | Blackwatch RushBlackwatch Ru |
| 09 Jul 22 | r63 | Tri-Cities OttersTri-Cities Ot | 1 - 0 | Dalton Red Wolves SCDalton Red Wo |
| |
| 09 Jul 22 | r64 | Tobacco Road FCTobacco Road | 1 - 4 | North Carolina FC U23North Carolin |
| |
| 09 Jul 22 | r63 | Flint City BucksFlint City Bu | 2 - 0 | AFC Ann ArborAFC Ann Arbor |
| 09 Jul 22 | r63 | Kalamazoo FCKalamazoo FC | 2 - 1 | Midwest United FCMidwest Unite |
| |
| 09 Jul 22 | r64 | Lansing City FootballLansing City | 1 - 2 | Oakland County FCOakland Count |
| 09 Jul 22 | r64 | Tormenta FC 2Tormenta FC 2 | - | SC United BantamsSC United Ban |
| |
| 09 Jul 22 | r63 | Colorado ISAColorado ISA | 0 - 2 | New Mexico United U-23New Mexico Un |
| |
| 09 Jul 22 | r64 | FC WichitaFC Wichita | - | Chicago Dutch Lions FCChicago Dutch |
| 09 Jul 22 | r64 | Ogden City SCOgden City SC | 2 - 1 | Colorado Rush SCColorado Rush |
| 09 Jul 22 | r64 | San Francisco City FCSan Francisco | 0 - 5 | Ventura County FusionVentura Count |
| 09 Jul 22 | r64 | Marin FC LegendsMarin FC Lege | 6 - 1 | Central Valley Fuego IICentral Valle |
| |
| 09 Jul 22 | r67 | AC ConnecticutAC Connecticu | 1 - 4 | Western Mass PioneersWestern Mass |
| 09 Jul 22 | r67 | Tampa Bay United SCTampa Bay Uni | 1 - 1 | FC Florida U23FC Florida U2 |
| |
| 09 Jul 22 | r64 | New Jersey Copa FCNew Jersey Co | 3 - 2 | Westchester FlamesWestchester F |
| |
| 09 Jul 22 | r11 | Morris Elite SCMorris Elite | 1 - 2 | Manhattan SCManhattan SC |
| |
| 10 Jul 22 | r25 | Philadelphia Lone Star FCPhiladelphia | 5 - 4 | Lehigh Valley UnitedLehigh Valley |
| |
| 10 Jul 22 | r65 | Wake FCWake FC | 0 - 8 | North Carolina Fusion U23North Carolin |
| 10 Jul 22 | r65 | Cedar Stars RushCedar Stars R | 1 - 3 | FA Euro New YorkFA Euro New Y |
| 10 Jul 22 | r65 | Reading United ACReading Unite | 1 - 2 | Real Central New JerseyReal Central |
| 10 Jul 22 | r65 | South Bend Lions FCSouth Bend Li | 3 - 1 | Toledo Villa FCToledo Villa |
| 10 Jul 22 | r65 | Charlotte EaglesCharlotte Eag | 3 - 1 | West Virginia UnitedWest Virginia |
| |
| 10 Jul 22 | r66 | FC Málaga City New YorkFC Málaga Cit | 0 - 1 | Boston BoltsBoston Bolts |
| |
| 10 Jul 22 | r02 | Christos FCChristos FC | 11 - 1 | Commonwealth Cardinals FCCommonwealth |
| |
| 10 Jul 22 | r65 | Hudson Valley HammersHudson Valley | 2 - 1 | FC Motown IIFC Motown II |
| 10 Jul 22 | r65 | Nona FCNona FC | 1 - 0 | The Villages SCThe Villages |
| 10 Jul 22 | r65 | Lionsbridge FCLionsbridge F | 8 - 0 | Patuxent Football AthletiPatuxent Foot |
| 10 Jul 22 | r65 | Cleveland Force SCCleveland For | 1 - 1 | Dayton Dutch LionsDayton Dutch |
| |
| 10 Jul 22 | r66 | Peachtree City MOBAPeachtree Cit | 5 - 1 | East Atlanta FCEast Atlanta |
| 10 Jul 22 | r66 | Asheville City SCAsheville Cit | 0 - 0 | Tennessee SCTennessee SC |
| 10 Jul 22 | r66 | One Knoxville SCOne Knoxville | 7 - 1 | Southern Soccer AcademySouthern Socc |
| 10 Jul 22 | r66 | Corpus Christi FCCorpus Christ | 1 - 0 | Houston FCHouston FC |
| 10 Jul 22 | r66 | Texas UnitedTexas United | 2 - 2 | Little Rock RangersLittle Rock R |
| |
| 10 Jul 22 | r28 | Chicago FC UnitedChicago FC Un | 3 - 1 | Springfield ASCSpringfield A |
| |
| 10 Jul 22 | r66 | AC Houston SurAC Houston Su | 3 - 2 | AHFC RoyalsAHFC Royals |
| 10 Jul 22 | r66 | Mississippi Brilla FCMississippi B | 3 - 2 | Louisiana Krewe FCLouisiana Kre |
| 10 Jul 22 | r66 | Des Moines MenaceDes Moines Me | 4 - 1 | St. Croix SCSt. Croix SC |
| |
| 10 Jul 22 | r67 | Kaw Valley FCKaw Valley FC | 2 - 2 | FC WichitaFC Wichita |
| |
| 10 Jul 22 | r64 | OVF AllianceOVF Alliance | 1 - 2 | Oly Town FCOly Town FC |
| |
| 10 Jul 22 | r67 | Ogden City SCOgden City SC | 2 - 3 | Colorado Rush SCColorado Rush |
| 10 Jul 22 | r67 | Virginia Beach United FCVirginia Beac | 0 - 1 | Patuxent Football AthletiPatuxent Foot |
| 10 Jul 22 | r67 | Midwest United FCMidwest Unite | 1 - 0 | Lansing City FootballLansing City |
| |
| 10 Jul 22 | r64 | San Francisco GlensSan Francisco | 7 - 0 | Central Valley Fuego IICentral Valle |
| |
| 10 Jul 22 | r67 | PDX FCPDX FC | 0 - 4 | Lane United FCLane United F |
| |
| 10 Jul 22 | r68 | Dayton Dutch LionsDayton Dutch | 0 - 5 | Fort Wayne FCFort Wayne FC |
| |
| 10 Jul 22 | r67 | Portland Timbers U23Portland Timb | 3 - 1 | Ballard FCBallard FC |
| |
| 10 Jul 22 | r68 | Kalamazoo FCKalamazoo FC | 2 - 2 | AFC Ann ArborAFC Ann Arbor |
| 10 Jul 22 | r68 | Kaw Valley FCKaw Valley FC | - | Chicago Dutch Lions FCChicago Dutch |
| 10 Jul 22 | r68 | FC Miami CityFC Miami City | 3 - 0 | Weston FCWeston FC |
| |
| 10 Jul 22 | r54 | Boston City FCBoston City F | 1 - 3 | Seacoast United PhantomsSeacoast Unit |
| |
| 10 Jul 22 | r68 | Marin FC LegendsMarin FC Lege | 2 - 2 | San Francisco City FCSan Francisco |
| 10 Jul 22 | r68 | Project 51OProject 51O | 3 - 0 | Davis Legacy SCDavis Legacy |
| 10 Jul 22 | r68 | Long Island Rough RidersLong Island R | 4 - 0 | Westchester FlamesWestchester F |
| |
| 11 Jul 22 | r30 | Kings Hammer FCKings Hammer | 4 - 1 | Cleveland Force SCCleveland For |
| |
| 11 Jul 22 | r52 | Blackwatch RushBlackwatch Ru | 0 - 3 | Vermont Green FCVermont Green |
| |
| 11 Jul 22 | r68 | Ocean City NoreastersOcean City No | 2 - 0 | West Chester United IIWest Chester |
| |
| 11 Jul 22 | r66 | Round Rock SCRound Rock SC | 0 - 3 | Brazos Valley Cavalry FCBrazos Valley |
| |
| 12 Jul 22 | r48 | Asheville City SCAsheville Cit | 2 - 0 | Tri-Cities OttersTri-Cities Ot |
| |
| 13 Jul 22 | r69 | North Carolina FC U23North Carolin | 1 - 1 | Charlotte EaglesCharlotte Eag |
| 13 Jul 22 | r69 | Wake FCWake FC | 1 - 3 | Tobacco Road FCTobacco Road |
| 13 Jul 22 | r69 | Commonwealth Cardinals FCCommonwealth | 0 - 4 | Lionsbridge FCLionsbridge F |
| 13 Jul 22 | r69 | Peachtree City MOBAPeachtree Cit | 5 - 2 | Tormenta FC 2Tormenta FC 2 |
| 13 Jul 22 | r69 | Southern Soccer AcademySouthern Socc | 2 - 2 | SC United BantamsSC United Ban |
| 13 Jul 22 | r69 | One Knoxville SCOne Knoxville | 0 - 1 | East Atlanta FCEast Atlanta |
| |
| 13 Jul 22 | r26 | FC Golden State ForceFC Golden Sta | 1 - 2 | Ventura County FusionVentura Count |
| |
| 13 Jul 22 | r69 | New Jersey Copa FCNew Jersey Co | 3 - 2 | FC Motown IIFC Motown II |
| |
| 13 Jul 22 | r70 | Weston FCWeston FC | 2 - 1 | FC Florida U23FC Florida U2 |
| |
| 13 Jul 22 | r77 | Chicago Dutch Lions FCChicago Dutch | 0 - 3 | Springfield ASCSpringfield A |
| |
| 14 Jul 22 | r69 | Dayton Dutch LionsDayton Dutch | 2 - 1 | Toledo Villa FCToledo Villa |
| |
| 14 Jul 22 | r70 | Lehigh Valley UnitedLehigh Valley | 1 - 4 | Real Central New JerseyReal Central |
| 14 Jul 22 | r70 | Cedar Stars RushCedar Stars R | 1 - 3 | Manhattan SCManhattan SC |
| |
| 14 Jul 22 | r25 | Boston BoltsBoston Bolts | 4 - 2 | Blackwatch RushBlackwatch Ru |
| |
| 14 Jul 22 | r70 | The Villages SCThe Villages | 3 - 0 | Miami ACMiami AC |
| 14 Jul 22 | r70 | Caledonia SCCaledonia SC | - | FC Miami CityFC Miami City |
| 14 Jul 22 | r70 | Vermont Green FCVermont Green | 8 - 0 | FC Málaga City New YorkFC Málaga Cit |
| |
| 14 Jul 22 | r50 | Northern Virginia FCNorthern Virg | 4 - 1 | Virginia Beach United FCVirginia Beac |
| |
| 14 Jul 22 | r70 | Long Island Rough RidersLong Island R | 6 - 1 | FA Euro New YorkFA Euro New Y |
| 14 Jul 22 | r70 | West Chester United IIWest Chester | 2 - 2 | Philadelphia Lone Star FCPhiladelphia |
| 14 Jul 22 | r70 | AFC Ann ArborAFC Ann Arbor | 3 - 0 | Midwest United FCMidwest Unite |
| |
| 14 Jul 22 | r09 | Louisiana Krewe FCLouisiana Kre | 7 - 2 | LA Parish ACLA Parish AC |
| |
| 14 Jul 22 | r69 | Chicago City SCChicago City | 3 - 3 | Saint LouisSaint Louis |
| |
| 14 Jul 22 | r71 | Patuxent Football AthletiPatuxent Foot | 0 - 4 | Christos FCChristos FC |
| 14 Jul 22 | r71 | Hudson Valley HammersHudson Valley | 8 - 0 | Morris Elite SCMorris Elite |
| 14 Jul 22 | r71 | Blue Goose SCBlue Goose SC | - | Mississippi Brilla FCMississippi B |
| 14 Jul 22 | r71 | Tennessee SCTennessee SC | 3 - 1 | Dalton Red Wolves SCDalton Red Wo |
| |
| 14 Jul 22 | r69 | Lansing City FootballLansing City | 0 - 2 | Flint City BucksFlint City Bu |
| |
| 14 Jul 22 | r07 | Marin FC LegendsMarin FC Lege | 0 - 0 | San Francisco GlensSan Francisco |
| |
| 15 Jul 22 | r71 | Round Rock SCRound Rock SC | 2 - 0 | Corpus Christi FCCorpus Christ |
| 15 Jul 22 | r71 | Brazos Valley Cavalry FCBrazos Valley | 3 - 1 | AHFC RoyalsAHFC Royals |
| 15 Jul 22 | r71 | Colorado Rush SCColorado Rush | 2 - 1 | New Mexico United U-23New Mexico Un |
| |
| 16 Jul 22 | r72 | Oakland County FCOakland Count | 2 - 4 | Kalamazoo FCKalamazoo FC |
| 16 Jul 22 | r72 | Kings Hammer FCKings Hammer | 4 - 1 | Dayton Dutch LionsDayton Dutch |
| 16 Jul 22 | r72 | Wake FCWake FC | 2 - 2 | North Carolina FC U23North Carolin |
| 16 Jul 22 | r72 | Thunder Bay ChillThunder Bay C | 1 - 3 | FC ManitobaFC Manitoba |
| 16 Jul 22 | r72 | Western Mass PioneersWestern Mass | 4 - 0 | AC ConnecticutAC Connecticu |
| 16 Jul 22 | r72 | Minneapolis CityMinneapolis C | 1 - 0 | St. Croix SCSt. Croix SC |
| 16 Jul 22 | r72 | Park City Red Wolves SCPark City Red | 0 - 1 | Colorado ISAColorado ISA |
| 16 Jul 22 | r72 | OVF AllianceOVF Alliance | 2 - 3 | Portland Timbers U23Portland Timb |
| 16 Jul 22 | r72 | Ventura County FusionVentura Count | 2 - 1 | FC Golden State ForceFC Golden Sta |
| 16 Jul 22 | r72 | PDX FCPDX FC | 2 - 0 | Oly Town FCOly Town FC |
| |
| 16 Jul 22 | r73 | Southern California SeahoSouthern Cali | 2 - 1 | San Francisco City FCSan Francisco |
| |
| 16 Jul 22 | r49 | Davis Legacy SCDavis Legacy | 2 - 1 | Marin FC LegendsMarin FC Lege |
| |
| 16 Jul 22 | r73 | Central Valley Fuego IICentral Valle | 4 - 2 | San Francisco GlensSan Francisco |
| 16 Jul 22 | r73 | Colorado Rush SCColorado Rush | 3 - 1 | New Mexico United U-23New Mexico Un |
| 16 Jul 22 | r73 | Manhattan SCManhattan SC | 5 - 0 | Westchester FlamesWestchester F |
| 16 Jul 22 | r73 | Miami ACMiami AC | 0 - 0 | Weston FCWeston FC |
| 16 Jul 22 | r73 | New Jersey Copa FCNew Jersey Co | 2 - 1 | Morris Elite SCMorris Elite |
| 16 Jul 22 | r73 | Saint LouisSaint Louis | 0 - 1 | Kaw Valley FCKaw Valley FC |
| |
| 16 Jul 22 | r49 | Blackwatch RushBlackwatch Ru | 1 - 3 | Boston City FCBoston City F |
| |
| 17 Jul 22 | r54 | West Virginia UnitedWest Virginia | 2 - 1 | North Carolina Fusion U23North Carolin |
| |
| 17 Jul 22 | r73 | Tampa Bay United SCTampa Bay Uni | - | FC Miami CityFC Miami City |
| |
| 17 Jul 22 | r74 | Tobacco Road FCTobacco Road | 2 - 3 | Charlotte EaglesCharlotte Eag |
| 17 Jul 22 | r74 | Boston BoltsBoston Bolts | 0 - 0 | FC Málaga City New YorkFC Málaga Cit |
| 17 Jul 22 | r74 | South Bend Lions FCSouth Bend Li | 8 - 0 | Dayton Dutch LionsDayton Dutch |
| 17 Jul 22 | r74 | Reading United ACReading Unite | 3 - 2 | Lehigh Valley UnitedLehigh Valley |
| |
| 17 Jul 22 | r75 | Philadelphia Lone Star FCPhiladelphia | 0 - 4 | Ocean City NoreastersOcean City No |
| |
| 17 Jul 22 | r74 | Lionsbridge FCLionsbridge F | 7 - 1 | Commonwealth Cardinals FCCommonwealth |
| 17 Jul 22 | r74 | Thunder Bay ChillThunder Bay C | 2 - 1 | FC ManitobaFC Manitoba |
| 17 Jul 22 | r74 | Fort Wayne FCFort Wayne FC | 3 - 0 | Cleveland Force SCCleveland For |
| 17 Jul 22 | r74 | Flint City BucksFlint City Bu | 6 - 0 | Midwest United FCMidwest Unite |
| 17 Jul 22 | r74 | The Villages SCThe Villages | 3 - 2 | Caledonia SCCaledonia SC |
| 17 Jul 22 | r74 | Virginia Beach United FCVirginia Beac | 1 - 3 | Christos FCChristos FC |
| |
| 17 Jul 22 | r75 | Springfield ASCSpringfield A | 2 - 4 | Chicago City SCChicago City |
| 17 Jul 22 | r75 | SC United BantamsSC United Ban | 3 - 3 | Asheville City SCAsheville Cit |
| 17 Jul 22 | r75 | Peachtree City MOBAPeachtree Cit | 2 - 3 | Tri-Cities OttersTri-Cities Ot |
| 17 Jul 22 | r75 | East Atlanta FCEast Atlanta | 1 - 1 | Dalton Red Wolves SCDalton Red Wo |
| 17 Jul 22 | r75 | Southern Soccer AcademySouthern Socc | 1 - 3 | Tennessee SCTennessee SC |
| 17 Jul 22 | r75 | Des Moines MenaceDes Moines Me | 2 - 0 | Peoria CityPeoria City |
| 17 Jul 22 | r75 | Mississippi Brilla FCMississippi B | 2 - 0 | Blue Goose SCBlue Goose SC |
| |
| 17 Jul 22 | r76 | Little Rock RangersLittle Rock R | 2 - 1 | Louisiana Krewe FCLouisiana Kre |
| 17 Jul 22 | r76 | AC Houston SurAC Houston Su | 3 - 3 | AHFC RoyalsAHFC Royals |
| 17 Jul 22 | r76 | Brazos Valley Cavalry FCBrazos Valley | 7 - 1 | Round Rock SCRound Rock SC |
| 17 Jul 22 | r76 | Park City Red Wolves SCPark City Red | 4 - 1 | Colorado ISAColorado ISA |
| 17 Jul 22 | r76 | Saint LouisSaint Louis | - | Kaw Valley FCKaw Valley FC |
| 17 Jul 22 | r76 | Manhattan SCManhattan SC | 2 - 0 | FC Motown IIFC Motown II |
| 17 Jul 22 | r76 | OVF AllianceOVF Alliance | 3 - 0 | Lane United FCLane United F |
| 17 Jul 22 | r76 | Ballard FCBallard FC | 8 - 1 | PDX FCPDX FC |
| |
| 17 Jul 22 | r75 | Northern Virginia FCNorthern Virg | 3 - 1 | Patuxent Football AthletiPatuxent Foot |
| |
| 17 Jul 22 | r76 | Seacoast United PhantomsSeacoast Unit | 2 - 0 | AC ConnecticutAC Connecticu |
| 17 Jul 22 | r76 | Vermont Green FCVermont Green | 1 - 0 | Western Mass PioneersWestern Mass |
| |
| 18 Jul 22 | r77 | Hudson Valley HammersHudson Valley | 3 - 5 | FA Euro New YorkFA Euro New Y |
| 18 Jul 22 | r77 | Round Rock SCRound Rock SC | 2 - 3 | Houston FCHouston FC |
| 18 Jul 22 | r77 | FC Golden State ForceFC Golden Sta | 2 - 0 | San Francisco City FCSan Francisco |
| 18 Jul 22 | r77 | Central Valley Fuego IICentral Valle | 2 - 2 | Project 51OProject 51O |
| |
| 20 Jul 22 | r29 | Christos FCChristos FC | - | Northern Virginia FCNorthern Virg |
| |
| 22 Jul 22 | r00 | Peoria CityPeoria City | 3 - 1 | Chicago FC UnitedChicago FC Un |
| 22 Jul 22 | r00 | Brazos Valley Cavalry FCBrazos Valley | 0 - 3 | Asheville City SCAsheville Cit |
| 22 Jul 22 | r00 | Nona FCNona FC | 1 - 2 | West Virginia UnitedWest Virginia |
| 22 Jul 22 | r00 | Seacoast United PhantomsSeacoast Unit | 4 - 1 | Christos FCChristos FC |
| 22 Jul 22 | r00 | Kalamazoo FCKalamazoo FC | 2 - 2 | Kings Hammer FCKings Hammer |
| 22 Jul 22 | r00 | Ocean City NoreastersOcean City No | 1 - 3 | Long Island Rough RidersLong Island R |
| 22 Jul 22 | r00 | Flint City BucksFlint City Bu | 3 - 1 | South Bend Lions FCSouth Bend Li |
| 22 Jul 22 | r00 | Western Mass PioneersWestern Mass | 1 - 0 | Manhattan SCManhattan SC |
| 23 Jul 22 | r00 | The Villages SCThe Villages | 1 - 1 | North Carolina Fusion U23North Carolin |
| 23 Jul 22 | r00 | South Bend Lions FCSouth Bend Li | 3 - 1 | Flint City BucksFlint City Bu |
| 23 Jul 22 | r00 | One Knoxville SCOne Knoxville | 4 - 2 | Texas UnitedTexas United |
| 23 Jul 22 | r00 | Lionsbridge FCLionsbridge F | 1 - 2 | Vermont Green FCVermont Green |
| 23 Jul 22 | r00 | Manhattan SCManhattan SC | 1 - 0 | Western Mass PioneersWestern Mass |
| 23 Jul 22 | r00 | Southern California SeahoSouthern Cali | 3 - 1 | Park City Red Wolves SCPark City Red |
| 23 Jul 22 | r00 | Des Moines MenaceDes Moines Me | 4 - 0 | Kaw Valley FCKaw Valley FC |
| 23 Jul 22 | r00 | Ballard FCBallard FC | 2 - 1 | Project 51OProject 51O |
| 23 Jul 22 | r00 | Project 51OProject 51O | 2 - 1 | Ballard FCBallard FC |
| 23 Jul 22 | r00 | Ventura County FusionVentura Count | 3 - 2 | Colorado Rush SCColorado Rush |
| 24 Jul 22 | r00 | Chicago FC UnitedChicago FC Un | 2 - 1 | Flint City BucksFlint City Bu |
| 24 Jul 22 | r00 | San Francisco GlensSan Francisco | 3 - 2 | Ballard FCBallard FC |
| 24 Jul 22 | r00 | Southern California SeahoSouthern Cali | 1 - 2 | Ventura County FusionVentura Count |
| 24 Jul 22 | r00 | Western Mass PioneersWestern Mass | 0 - 1 | Seacoast United PhantomsSeacoast Unit |
| 24 Jul 22 | r00 | One Knoxville SCOne Knoxville | 2 - 0 | West Virginia UnitedWest Virginia |
| 25 Jul 22 | r00 | Long Island Rough RidersLong Island R | 2 - 1 | Vermont Green FCVermont Green |
| 25 Jul 22 | r00 | Seacoast United PhantomsSeacoast Unit | 0 - 1 | Western Mass PioneersWestern Mass |
| 25 Jul 22 | r00 | North Carolina Fusion U23North Carolin | 2 - 1 | Asheville City SCAsheville Cit |
| 25 Jul 22 | r00 | Ventura County FusionVentura Count | 1 - 2 | Southern California SeahoSouthern Cali |
| 25 Jul 22 | r00 | West Virginia UnitedWest Virginia | 2 - 0 | One Knoxville SCOne Knoxville |
| 25 Jul 22 | r00 | Des Moines MenaceDes Moines Me | 4 - 1 | Kings Hammer FCKings Hammer |
| 29 Jul 22 | r00 | Seacoast United PhantomsSeacoast Unit | 1 - 2 | Long Island Rough RidersLong Island R |
| 29 Jul 22 | r00 | Ballard FCBallard FC | 0 - 1 | Ventura County FusionVentura Count |
| 29 Jul 22 | r00 | Long Island Rough RidersLong Island R | 1 - 2 | Seacoast United PhantomsSeacoast Unit |
| 30 Jul 22 | r00 | One Knoxville SCOne Knoxville | 1 - 1 | North Carolina Fusion U23North Carolin |
| 30 Jul 22 | r00 | One Knoxville SCOne Knoxville | 1 - 2 | North Carolina Fusion U23North Carolin |
| 30 Jul 22 | r00 | Des Moines MenaceDes Moines Me | 1 - 1 | Flint City BucksFlint City Bu |
| 01 Aug 22 | r00  | Ventura County FusionVentura Count | 1 - 0 | Flint City BucksFlint City Bu |
| 01 Aug 22 | r00 | North Carolina Fusion U23North Carolin | 0 - 2 | Long Island Rough RidersLong Island R |
| 07 Aug 22 | r00 | Ventura County FusionVentura Count | 2 - 1 | Long Island Rough RidersLong Island R |
Team 2022 Schedules
AC Connecticut
AC Houston Sur
Academica SC
AFC Ann Arbor
AHFC Royals
Akron City
Albany Rush
Albion SC Colorado
Almaden FC
AMSG FC
Annapolis Blues
Apotheos FC
Appalachian
Asheville City SC
Ballard FC
Bethesda SC
Bigfoot FC
Birmingham Legion 2
Black Rock FC
Boston Bolts
Boston City
Brave SC
Brevard SC
Brooke House
Cedar Stars Rush
Charlotte Eagles
Charlotte Independence II
Charlottesville Blues
Chicago City Dutch Lions
Christos FC
CISA
City SC
Cleveland Force
Colorado Storm
Columbus United
Connecticut Rush
Davis Legacy
Dayton Dutch Lions
Delaware FC
Denton Diablos
Des Moines Menace
Dothan United
Eagle FC
East Atlanta
Edgewater Castle
Erie Sports Center
FC Buffalo
FC Capo II
FC Miami City
FC Olympia
FC Tucson
Flatirons FC
Flint City Bucks
Fort Lauderdale United
Fort Worth Vaqueros
GFI Academy
Hattiesburg FC
Hickory FC
Hill City
Hill Country Lobos
Houston FC
Hudson Valley Hammers
Inter Gainesville
Ironbound SC
Jackson Boom
Kalamazoo FC
Kings Hammer Columbus
Lakeland United
Lansing City Football
Laredo Heat
Lehigh Valley United
Lionsbridge FC
Little Rock Rangers
Lonestar SC
Long Island Rough Riders
Lorain County Leviathan
Loudoun United 2
Louisiana Krewe
Louisville City II
Lubbock Matadors
Manhattan SC
Marin FC Legends
McKinney Chupacabras
Memphis FC
Miami AC
Midlakes United
Midwest United
Minneapolis City
Mississippi Brilla
Montgomery United
Morris Elite
Motown STA
New England FC
New Jersey Copa
Nona FC
North Carolina FC U23
Northern Indiana
Northern Virginia FC
Oakland County
Ocean City Nor'easters
Patuxent Football Athletics
Pennsylvania Classics
Peoria City
Pittsburgh Riverhounds 2
Port City
Portland Bangers
Project 51O
Reading United
Real Central New Jersey
Real Colorado
Red River
Redlands FC
River Light
RKC Third Coast
Rochester FC
Rockford Raptors
Salem City
San Antonio FC 2
San Francisco City FC
San Francisco Glens
San Juan SC
Santafé Wanderers
Seacoast United Phantoms
Shark Coast
Snohomish United
South Carolina United
Southern California Eagles
Sporting JAX II
Springfield FC
St. Croix Legends
St. Louis Ambush
Stars FC
Staten Island Athletic
Steel City
Sueño FC
Sunflower State
Swarm FC
Tacoma Stars
Texoma
Tobacco Road
Toledo Villa
Twin City Toucans
Union FC Macomb
Utah United
Ventura County Fusion
Vermont Green
Virginia Beach United
Virginia Marauders
Wake FC
West Chester United II
West Seattle Junction
West Texas
West Virginia United
Westchester Flames
Western Mass Pioneers
Weston FC
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