| 16 Feb 25 | r00        | Houston SaberCatsHouston Saber | 22 - 25 | Chicago HoundsChicago Hound |
| 23 Feb 25 | r00        | Chicago HoundsChicago Hound | 31 - 45 | Utah WarriorsUtah Warriors |
| 02 Mar 25 | r00        | Chicago HoundsChicago Hound | 36 - 7 | New England Free JacksNew England F |
| 08 Mar 25 | r00        | Miami SharksMiami Sharks | 18 - 31 | Chicago HoundsChicago Hound |
| 15 Mar 25 | r00        | Chicago HoundsChicago Hound | 30 - 26 | Old Glory DCOld Glory DC |
| 29 Mar 25 | r00        | New Orleans GoldNew Orleans G | 18 - 20 | Chicago HoundsChicago Hound |
| 06 Apr 25 | r00        | San Diego LegionSan Diego Leg | 20 - 27 | Chicago HoundsChicago Hound |
| 13 Apr 25 | r00        | Chicago HoundsChicago Hound | 28 - 20 | Anthem RCAnthem RC |
| 19 Apr 25 | r00        | Seattle SeawolvesSeattle Seawo | 28 - 22 | Chicago HoundsChicago Hound |
| 27 Apr 25 | r00        | Utah WarriorsUtah Warriors | 41 - 31 | Chicago HoundsChicago Hound |
| 04 May 25 | r00        | Chicago HoundsChicago Hound | 14 - 7 | Miami SharksMiami Sharks |
| 10 May 25 | r00        | New England Free JacksNew England F | 27 - 17 | Chicago HoundsChicago Hound |
| 20 May 25 | r00        | Chicago HoundsChicago Hound | 24 - 26 | Rugby FC Los AngelesRugby FC Los |
| 24 May 25 | r00        | Anthem RCAnthem RC | 19 - 33 | Chicago HoundsChicago Hound |
| 31 May 25 | r00        | Chicago HoundsChicago Hound | 38 - 17 | New Orleans GoldNew Orleans G |
| 04 Jun 25 | r00        | Chicago HoundsChicago Hound | 15 - 12 | Houston SaberCatsHouston Saber |
| 14 Jun 25 | r00        | Chicago HoundsChicago Hound | 27 - 16 | Old Glory DCOld Glory DC |
| 21 Jun 25 | r00        | New England Free JacksNew England F | 21 - 20 | Chicago HoundsChicago Hound |