| 21 Mar 21 | r00        | Houston SaberCatsHouston Saber | 30 - 24 | Seattle SeawolvesSeattle Seawo |
| 29 Mar 21 | r00        | LA GiltinisLA Giltinis | 57 - 26 | Seattle SeawolvesSeattle Seawo |
| 11 Apr 21 | r00        | Utah WarriorsUtah Warriors | 15 - 20 | Seattle SeawolvesSeattle Seawo |
| 17 Apr 21 | r00        | Toronto ArrowsToronto Arrow | 52 - 7 | Seattle SeawolvesSeattle Seawo |
| 25 Apr 21 | r00        | Austin GilgronisAustin Gilgro | 42 - 15 | Seattle SeawolvesSeattle Seawo |
| 03 May 21 | r00        | Seattle SeawolvesSeattle Seawo | 21 - 23 | Rugby United New YorkRugby United |
| 10 May 21 | r00        | Seattle SeawolvesSeattle Seawo | 21 - 15 | San Diego LegionSan Diego Leg |
| 16 May 21 | r00        | Old Glory DCOld Glory DC | 22 - 18 | Seattle SeawolvesSeattle Seawo |
| 24 May 21 | r00        | Seattle SeawolvesSeattle Seawo | 6 - 25 | Rugby ATLRugby ATL |
| 07 Jun 21 | r00        | Seattle SeawolvesSeattle Seawo | 28 - 29 | Utah WarriorsUtah Warriors |
| 13 Jun 21 | r00        | New England Free JacksNew England F | 25 - 21 | Seattle SeawolvesSeattle Seawo |
| 21 Jun 21 | r00        | Seattle SeawolvesSeattle Seawo | 31 - 36 | Austin GilgronisAustin Gilgro |
| 28 Jun 21 | r00        | Seattle SeawolvesSeattle Seawo | 14 - 29 | LA GiltinisLA Giltinis |
| 03 Jul 21 | r00        | San Diego LegionSan Diego Leg | 34 - 21 | Seattle SeawolvesSeattle Seawo |
| 12 Jul 21 | r00        | Seattle SeawolvesSeattle Seawo | 30 - 6 | New Orleans GoldNew Orleans G |
| 16 Jul 21 | r00        | Seattle SeawolvesSeattle Seawo | 40 - 21 | Houston SaberCatsHouston Saber |