| 08 Sep 24 | r01  | Karela UnitedKarela United | 0 - 1 | Asante KotokoAsante Kotoko |
| |
| 15 Sep 24 | r02 | Berekum ChelseaBerekum Chels | 1 - 0 | Karela UnitedKarela United |
| |
| 22 Sep 24 | r03 | Karela UnitedKarela United | 1 - 1 | Accra LionsAccra Lions |
| |
| 29 Sep 24 | r04 | Legon CitiesLegon Cities | 0 - 2 | Karela UnitedKarela United |
| |
| 06 Oct 24 | r05 | Karela UnitedKarela United | 1 - 1 | SamartexSamartex |
| |
| 13 Oct 24 | r06 | Basake Holy StarsBasake Holy S | 1 - 0 | Karela UnitedKarela United |
| |
| 20 Oct 24 | r07 | Karela UnitedKarela United | 1 - 0 | Heart of LionsHeart of Lion |
| |
| 27 Oct 24 | r08 | Bechem UnitedBechem United | 0 - 0 | Karela UnitedKarela United |
| |
| 03 Nov 24 | r09 | Karela UnitedKarela United | 0 - 1 | Nations FCNations FC |
| |
| 10 Nov 24 | r10 | Aduana StarsAduana Stars | 1 - 0 | Karela UnitedKarela United |
| |
| 17 Nov 24 | r11 | Karela UnitedKarela United | 0 - 1 | Hearts of OakHearts of Oak |
| |
| 24 Nov 24 | r12 | Dreams FCDreams FC | 0 - 1 | Karela UnitedKarela United |
| |
| 14 Dec 24 | r13 | Karela UnitedKarela United | 1 - 1 | Bibiani Gold StarsBibiani Gold |
| |
| 29 Dec 24 | r15 | Karela UnitedKarela United | 1 - 1 | VisionVision |
| |
| 01 Jan 25 | r14 | MedeamaMedeama | 1 - 0 | Karela UnitedKarela United |
| |
| 05 Jan 25 | r16 | Young ApostlesYoung Apostle | 2 - 0 | Karela UnitedKarela United |
| |
| 19 Jan 25 | r17 | NsoatremanNsoatreman | 1 - 0 | Karela UnitedKarela United |
| |
| 26 Jan 25 | r18 | Asante KotokoAsante Kotoko | 1 - 0 | Karela UnitedKarela United |
| |
| 02 Feb 25 | r19 | Karela UnitedKarela United | 2 - 1 | Berekum ChelseaBerekum Chels |
| |
| 09 Mar 25 | r23 | Karela UnitedKarela United | 1 - 1 | Basake Holy StarsBasake Holy S |
| |
| 16 Mar 25 | r24 | Heart of LionsHeart of Lion | 1 - 0 | Karela UnitedKarela United |
| |
| 20 Mar 25 | r20 | Accra LionsAccra Lions | 0 - 0 | Karela UnitedKarela United |
| |
| 23 Mar 25 | r25 | Karela UnitedKarela United | 2 - 1 | Bechem UnitedBechem United |
| |
| 02 Apr 25 | r21 | Karela UnitedKarela United | 2 - 0 | Legon CitiesLegon Cities |
| |
| 07 Apr 25 | r26 | Nations FCNations FC | 1 - 0 | Karela UnitedKarela United |
| |
| 13 Apr 25 | r27 | Karela UnitedKarela United | 2 - 0 | Aduana StarsAduana Stars |
| |
| 16 Apr 25 | r22 | SamartexSamartex | 2 - 0 | Karela UnitedKarela United |
| |
| 20 Apr 25 | r28 | Hearts of OakHearts of Oak | 0 - 0 | Karela UnitedKarela United |
| |
| 27 Apr 25 | r29 | Karela UnitedKarela United | 1 - 2 | Dreams FCDreams FC |
| |
| 04 May 25 | r30 | Bibiani Gold StarsBibiani Gold | 0 - 1 | Karela UnitedKarela United |
| |
| 18 May 25 | r31 | Karela UnitedKarela United | 3 - 1 | MedeamaMedeama |
| |
| 25 May 25 | r32 | VisionVision | 1 - 0 | Karela UnitedKarela United |
| |
| 01 Jun 25 | r33 | Karela UnitedKarela United | 3 - 0 | Young ApostlesYoung Apostle |
| |
| 07 Jun 25 | r34 | Karela UnitedKarela United | - | NsoatremanNsoatreman |
Team 2024-2025 Schedules
Aduana Stars
Asante Kotoko
Basake Holy Stars
Bechem United
Berekum Chelsea
Bibiani Gold Stars
Dreams FC
Eleven Wonders
Heart of Lions
Hearts of Oak
Hohoe United
Karela United
Medeama
Nations FC
Samartex
Swedru All Blacks
Vision
Young Apostles
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