| 15 Nov 20 | r01  | Ashanti GoldAshanti Gold | 2 - 2 | Karela UnitedKarela United |
| |
| 24 Nov 20 | r02 | Hearts of OakHearts of Oak | 2 - 2 | Ashanti GoldAshanti Gold |
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| 13 Dec 20 | r05 | Ashanti GoldAshanti Gold | 4 - 2 | Elmina SharksElmina Sharks |
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| 16 Dec 20 | r03 | Ashanti GoldAshanti Gold | 5 - 1 | King FaisalKing Faisal |
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| 20 Dec 20 | r06 | Eleven WondersEleven Wonder | 1 - 1 | Ashanti GoldAshanti Gold |
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| 27 Dec 20 | r04 | Bechem UnitedBechem United | 1 - 0 | Ashanti GoldAshanti Gold |
| |
| 03 Jan 21 | r07 | Ashanti GoldAshanti Gold | 2 - 1 | Berekum ChelseaBerekum Chels |
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| 10 Jan 21 | r08 | Great OlympicsGreat Olympic | 1 - 2 | Ashanti GoldAshanti Gold |
| |
| 17 Jan 21 | r09 | Ashanti GoldAshanti Gold | 0 - 0 | MedeamaMedeama |
| |
| 22 Jan 21 | r10 | Legon CitiesLegon Cities | 5 - 2 | Ashanti GoldAshanti Gold |
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| 31 Jan 21 | r11 | Ashanti GoldAshanti Gold | 0 - 0 | Asante KotokoAsante Kotoko |
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| 03 Feb 21 | r12 | Ebusua DwarfsEbusua Dwarfs | 2 - 1 | Ashanti GoldAshanti Gold |
| |
| 07 Feb 21 | r13 | Ashanti GoldAshanti Gold | 0 - 1 | Liberty ProfessionalsLiberty Profe |
| |
| 13 Feb 21 | r14 | WAFAWAFA | 0 - 0 | Ashanti GoldAshanti Gold |
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| 19 Feb 21 | r15 | Ashanti GoldAshanti Gold | 4 - 0 | Aduana StarsAduana Stars |
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| 25 Feb 21 | r16 | Dreams FCDreams FC | 4 - 1 | Ashanti GoldAshanti Gold |
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| 05 Mar 21 | r17 | Inter AlliesInter Allies | 1 - 1 | Ashanti GoldAshanti Gold |
| |
| 04 Apr 21 | r18 | Karela UnitedKarela United | 1 - 1 | Ashanti GoldAshanti Gold |
| |
| 10 Apr 21 | r19 | Ashanti GoldAshanti Gold | 1 - 0 | Hearts of OakHearts of Oak |
| |
| 17 Apr 21 | r20 | King FaisalKing Faisal | 0 - 0 | Ashanti GoldAshanti Gold |
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| 25 Apr 21 | r21 | Ashanti GoldAshanti Gold | 4 - 0 | Bechem UnitedBechem United |
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| 02 May 21 | r22 | Elmina SharksElmina Sharks | 2 - 1 | Ashanti GoldAshanti Gold |
| |
| 09 May 21 | r23 | Ashanti GoldAshanti Gold | 1 - 1 | Eleven WondersEleven Wonder |
| |
| 12 May 21 | r24 | Berekum ChelseaBerekum Chels | 3 - 1 | Ashanti GoldAshanti Gold |
| |
| 16 May 21 | r25 | Ashanti GoldAshanti Gold | 1 - 0 | Great OlympicsGreat Olympic |
| |
| 23 May 21 | r26 | MedeamaMedeama | 1 - 0 | Ashanti GoldAshanti Gold |
| |
| 30 May 21 | r27 | Ashanti GoldAshanti Gold | 0 - 1 | Legon CitiesLegon Cities |
| |
| 06 Jun 21 | r28 | Asante KotokoAsante Kotoko | 1 - 0 | Ashanti GoldAshanti Gold |
| |
| 13 Jun 21 | r29 | Ashanti GoldAshanti Gold | 1 - 0 | Ebusua DwarfsEbusua Dwarfs |
| |
| 24 Jun 21 | r30 | Liberty ProfessionalsLiberty Profe | 1 - 5 | Ashanti GoldAshanti Gold |
| |
| 27 Jun 21 | r31 | Ashanti GoldAshanti Gold | 0 - 0 | WAFAWAFA |
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| 05 Jul 21 | r32 | Aduana StarsAduana Stars | 1 - 0 | Ashanti GoldAshanti Gold |
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| 11 Jul 21 | r33 | Ashanti GoldAshanti Gold | 0 - 0 | Dreams FCDreams FC |
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| 17 Jul 21 | r34 | Ashanti GoldAshanti Gold | 7 - 0 | Inter AlliesInter Allies |
Team 2020-2021 Schedules
Aduana Stars
Asante Kotoko
Ashanti Gold
Basake Holy Stars
Bechem United
Berekum Chelsea
Bibiani Gold Stars
Debibi United
Dreams FC
Heart of Lions
Hearts of Oak
Karela United
Medeama
Port City FC
Samartex
Swedru All Blacks
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