| 14 Nov 20 | r01  | Legon CitiesLegon Cities | 1 - 1 | Berekum ChelseaBerekum Chels |
| 15 Nov 20 | r01 | WAFAWAFA | 4 - 3 | King FaisalKing Faisal |
| 15 Nov 20 | r01 | Ashanti GoldAshanti Gold | 2 - 2 | Karela UnitedKarela United |
| 15 Nov 20 | r01 | MedeamaMedeama | 1 - 1 | Great OlympicsGreat Olympic |
| 15 Nov 20 | r01 | Ebusua DwarfsEbusua Dwarfs | 2 - 2 | Elmina SharksElmina Sharks |
| 15 Nov 20 | r01 | Asante KotokoAsante Kotoko | 1 - 1 | Eleven WondersEleven Wonder |
| 16 Nov 20 | r01 | Liberty ProfessionalsLiberty Profe | 1 - 1 | Bechem UnitedBechem United |
| 16 Nov 20 | r01 | Inter AlliesInter Allies | 0 - 0 | Dreams FCDreams FC |
| |
| 20 Nov 20 | r02 | Eleven WondersEleven Wonder | 2 - 0 | Ebusua DwarfsEbusua Dwarfs |
| 20 Nov 20 | r02 | Great OlympicsGreat Olympic | 3 - 0 | Legon CitiesLegon Cities |
| 21 Nov 20 | r02 | Bechem UnitedBechem United | 1 - 0 | WAFAWAFA |
| 22 Nov 20 | r02 | Berekum ChelseaBerekum Chels | 1 - 1 | Asante KotokoAsante Kotoko |
| 22 Nov 20 | r02 | Dreams FCDreams FC | 2 - 1 | MedeamaMedeama |
| 22 Nov 20 | r02 | King FaisalKing Faisal | 1 - 1 | Aduana StarsAduana Stars |
| 22 Nov 20 | r02 | Elmina SharksElmina Sharks | 1 - 1 | Liberty ProfessionalsLiberty Profe |
| 22 Nov 20 | r02 | Karela UnitedKarela United | 1 - 0 | Inter AlliesInter Allies |
| 24 Nov 20 | r02 | Hearts of OakHearts of Oak | 2 - 2 | Ashanti GoldAshanti Gold |
| |
| 27 Nov 20 | r03 | Legon CitiesLegon Cities | 0 - 0 | MedeamaMedeama |
| 28 Nov 20 | r03 | Liberty ProfessionalsLiberty Profe | 1 - 1 | Eleven WondersEleven Wonder |
| 29 Nov 20 | r03 | WAFAWAFA | 1 - 1 | Elmina SharksElmina Sharks |
| 29 Nov 20 | r03 | Ebusua DwarfsEbusua Dwarfs | 1 - 0 | Berekum ChelseaBerekum Chels |
| 29 Nov 20 | r03 | Aduana StarsAduana Stars | 0 - 0 | Bechem UnitedBechem United |
| 29 Nov 20 | r03 | Karela UnitedKarela United | 2 - 1 | Dreams FCDreams FC |
| 29 Nov 20 | r03 | Inter AlliesInter Allies | 1 - 0 | Hearts of OakHearts of Oak |
| |
| 03 Dec 20 | r04 | Elmina SharksElmina Sharks | 1 - 0 | Aduana StarsAduana Stars |
| 04 Dec 20 | r04 | King FaisalKing Faisal | 1 - 0 | Inter AlliesInter Allies |
| 04 Dec 20 | r04 | Hearts of OakHearts of Oak | 0 - 0 | Karela UnitedKarela United |
| 05 Dec 20 | r04 | Berekum ChelseaBerekum Chels | 1 - 0 | Liberty ProfessionalsLiberty Profe |
| 05 Dec 20 | r04 | Dreams FCDreams FC | 0 - 0 | Legon CitiesLegon Cities |
| 05 Dec 20 | r04 | Eleven WondersEleven Wonder | 0 - 1 | WAFAWAFA |
| |
| 11 Dec 20 | r05 | Asante KotokoAsante Kotoko | 1 - 0 | Legon CitiesLegon Cities |
| 12 Dec 20 | r05 | Inter AlliesInter Allies | 1 - 2 | Bechem UnitedBechem United |
| 12 Dec 20 | r05 | Ebusua DwarfsEbusua Dwarfs | 0 - 1 | MedeamaMedeama |
| 13 Dec 20 | r05 | WAFAWAFA | 2 - 0 | Berekum ChelseaBerekum Chels |
| 13 Dec 20 | r05 | Ashanti GoldAshanti Gold | 4 - 2 | Elmina SharksElmina Sharks |
| 13 Dec 20 | r05 | Liberty ProfessionalsLiberty Profe | 2 - 0 | Great OlympicsGreat Olympic |
| 13 Dec 20 | r05 | Aduana StarsAduana Stars | 1 - 1 | Eleven WondersEleven Wonder |
| 13 Dec 20 | r05 | Karela UnitedKarela United | 2 - 0 | King FaisalKing Faisal |
| 13 Dec 20 | r05 | Hearts of OakHearts of Oak | 3 - 0 | Dreams FCDreams FC |
| |
| 16 Dec 20 | r01 | Aduana StarsAduana Stars | 2 - 0 | Hearts of OakHearts of Oak |
| |
| 16 Dec 20 | r03 | Ashanti GoldAshanti Gold | 5 - 1 | King FaisalKing Faisal |
| 17 Dec 20 | r03 | Asante KotokoAsante Kotoko | 0 - 1 | Great OlympicsGreat Olympic |
| |
| 18 Dec 20 | r06 | Bechem UnitedBechem United | 2 - 1 | Karela UnitedKarela United |
| 18 Dec 20 | r06 | Legon CitiesLegon Cities | 1 - 2 | Ebusua DwarfsEbusua Dwarfs |
| 19 Dec 20 | r06 | King FaisalKing Faisal | 1 - 2 | Hearts of OakHearts of Oak |
| 20 Dec 20 | r06 | Great OlympicsGreat Olympic | 1 - 0 | WAFAWAFA |
| 20 Dec 20 | r06 | Dreams FCDreams FC | 0 - 1 | Asante KotokoAsante Kotoko |
| 20 Dec 20 | r06 | MedeamaMedeama | 0 - 0 | Liberty ProfessionalsLiberty Profe |
| 20 Dec 20 | r06 | Elmina SharksElmina Sharks | 1 - 0 | Inter AlliesInter Allies |
| 20 Dec 20 | r06 | Eleven WondersEleven Wonder | 1 - 1 | Ashanti GoldAshanti Gold |
| 21 Dec 20 | r06 | Berekum ChelseaBerekum Chels | 1 - 1 | Aduana StarsAduana Stars |
| |
| 24 Dec 20 | r04 | Great OlympicsGreat Olympic | 1 - 1 | Ebusua DwarfsEbusua Dwarfs |
| 27 Dec 20 | r04 | MedeamaMedeama | 1 - 1 | Asante KotokoAsante Kotoko |
| 27 Dec 20 | r04 | Bechem UnitedBechem United | 1 - 0 | Ashanti GoldAshanti Gold |
| |
| 01 Jan 21 | r07 | King FaisalKing Faisal | 1 - 1 | Dreams FCDreams FC |
| 02 Jan 21 | r07 | Hearts of OakHearts of Oak | 6 - 1 | Bechem UnitedBechem United |
| 03 Jan 21 | r07 | Inter AlliesInter Allies | 1 - 0 | Eleven WondersEleven Wonder |
| 03 Jan 21 | r07 | WAFAWAFA | 5 - 4 | MedeamaMedeama |
| 03 Jan 21 | r07 | Ashanti GoldAshanti Gold | 2 - 1 | Berekum ChelseaBerekum Chels |
| 03 Jan 21 | r07 | Liberty ProfessionalsLiberty Profe | 1 - 0 | Legon CitiesLegon Cities |
| 03 Jan 21 | r07 | Aduana StarsAduana Stars | 2 - 1 | Great OlympicsGreat Olympic |
| 03 Jan 21 | r07 | Karela UnitedKarela United | 3 - 1 | Elmina SharksElmina Sharks |
| |
| 08 Jan 21 | r08 | Legon CitiesLegon Cities | 1 - 0 | WAFAWAFA |
| 09 Jan 21 | r08 | MedeamaMedeama | 2 - 1 | Aduana StarsAduana Stars |
| 10 Jan 21 | r08 | Berekum ChelseaBerekum Chels | 1 - 0 | Inter AlliesInter Allies |
| 10 Jan 21 | r08 | Great OlympicsGreat Olympic | 1 - 2 | Ashanti GoldAshanti Gold |
| 10 Jan 21 | r08 | Dreams FCDreams FC | 2 - 0 | Ebusua DwarfsEbusua Dwarfs |
| 10 Jan 21 | r08 | Bechem UnitedBechem United | 1 - 1 | King FaisalKing Faisal |
| 10 Jan 21 | r08 | Eleven WondersEleven Wonder | 3 - 1 | Karela UnitedKarela United |
| 10 Jan 21 | r08 | Elmina SharksElmina Sharks | 1 - 1 | Hearts of OakHearts of Oak |
| 11 Jan 21 | r08 | Asante KotokoAsante Kotoko | 2 - 0 | Liberty ProfessionalsLiberty Profe |
| |
| 15 Jan 21 | r09 | Inter AlliesInter Allies | 0 - 2 | Great OlympicsGreat Olympic |
| 16 Jan 21 | r09 | Liberty ProfessionalsLiberty Profe | 1 - 2 | Ebusua DwarfsEbusua Dwarfs |
| 17 Jan 21 | r09 | WAFAWAFA | 1 - 1 | Asante KotokoAsante Kotoko |
| 17 Jan 21 | r09 | King FaisalKing Faisal | 1 - 1 | Elmina SharksElmina Sharks |
| 17 Jan 21 | r09 | Ashanti GoldAshanti Gold | 0 - 0 | MedeamaMedeama |
| 17 Jan 21 | r09 | Aduana StarsAduana Stars | 2 - 1 | Legon CitiesLegon Cities |
| 17 Jan 21 | r09 | Bechem UnitedBechem United | 1 - 1 | Dreams FCDreams FC |
| 17 Jan 21 | r09 | Karela UnitedKarela United | 4 - 1 | Berekum ChelseaBerekum Chels |
| 17 Jan 21 | r09 | Hearts of OakHearts of Oak | 2 - 0 | Eleven WondersEleven Wonder |
| |
| 20 Jan 21 | r07 | Ebusua DwarfsEbusua Dwarfs | 0 - 1 | Asante KotokoAsante Kotoko |
| |
| 22 Jan 21 | r10 | Legon CitiesLegon Cities | 5 - 2 | Ashanti GoldAshanti Gold |
| 23 Jan 21 | r10 | Berekum ChelseaBerekum Chels | 0 - 0 | Hearts of OakHearts of Oak |
| 23 Jan 21 | r10 | Great OlympicsGreat Olympic | 0 - 0 | Karela UnitedKarela United |
| 24 Jan 21 | r10 | Dreams FCDreams FC | 4 - 1 | Liberty ProfessionalsLiberty Profe |
| 24 Jan 21 | r10 | MedeamaMedeama | 2 - 1 | Inter AlliesInter Allies |
| 24 Jan 21 | r10 | Ebusua DwarfsEbusua Dwarfs | 1 - 1 | WAFAWAFA |
| 24 Jan 21 | r10 | Elmina SharksElmina Sharks | 2 - 1 | Bechem UnitedBechem United |
| 24 Jan 21 | r10 | Eleven WondersEleven Wonder | 1 - 0 | King FaisalKing Faisal |
| 24 Jan 21 | r10 | Asante KotokoAsante Kotoko | 0 - 1 | Aduana StarsAduana Stars |
| |
| 29 Jan 21 | r11 | Bechem UnitedBechem United | 3 - 1 | Eleven WondersEleven Wonder |
| 30 Jan 21 | r11 | King FaisalKing Faisal | 4 - 3 | Berekum ChelseaBerekum Chels |
| 30 Jan 21 | r11 | Hearts of OakHearts of Oak | 0 - 2 | Great OlympicsGreat Olympic |
| 31 Jan 21 | r11 | Inter AlliesInter Allies | 0 - 1 | Legon CitiesLegon Cities |
| 31 Jan 21 | r11 | WAFAWAFA | 5 - 0 | Liberty ProfessionalsLiberty Profe |
| 31 Jan 21 | r11 | Ashanti GoldAshanti Gold | 0 - 0 | Asante KotokoAsante Kotoko |
| 31 Jan 21 | r11 | Elmina SharksElmina Sharks | 2 - 2 | Dreams FCDreams FC |
| 31 Jan 21 | r11 | Aduana StarsAduana Stars | 2 - 2 | Ebusua DwarfsEbusua Dwarfs |
| 31 Jan 21 | r11 | Karela UnitedKarela United | 2 - 0 | MedeamaMedeama |
| |
| 02 Feb 21 | r12 | Great OlympicsGreat Olympic | 3 - 1 | King FaisalKing Faisal |
| 03 Feb 21 | r12 | Berekum ChelseaBerekum Chels | 2 - 0 | Bechem UnitedBechem United |
| 03 Feb 21 | r12 | Dreams FCDreams FC | 3 - 0 | WAFAWAFA |
| 03 Feb 21 | r12 | Ebusua DwarfsEbusua Dwarfs | 2 - 1 | Ashanti GoldAshanti Gold |
| 03 Feb 21 | r12 | Liberty ProfessionalsLiberty Profe | 0 - 0 | Aduana StarsAduana Stars |
| 03 Feb 21 | r12 | Eleven WondersEleven Wonder | 0 - 0 | Elmina SharksElmina Sharks |
| 03 Feb 21 | r12 | Asante KotokoAsante Kotoko | 1 - 0 | Inter AlliesInter Allies |
| 04 Feb 21 | r12 | Legon CitiesLegon Cities | 0 - 0 | Karela UnitedKarela United |
| 04 Feb 21 | r12 | MedeamaMedeama | 1 - 0 | Hearts of OakHearts of Oak |
| |
| 06 Feb 21 | r13 | Inter AlliesInter Allies | 0 - 2 | Ebusua DwarfsEbusua Dwarfs |
| 07 Feb 21 | r13 | Ashanti GoldAshanti Gold | 0 - 1 | Liberty ProfessionalsLiberty Profe |
| 07 Feb 21 | r13 | Aduana StarsAduana Stars | 1 - 0 | WAFAWAFA |
| 07 Feb 21 | r13 | Bechem UnitedBechem United | 3 - 1 | Great OlympicsGreat Olympic |
| 07 Feb 21 | r13 | Karela UnitedKarela United | 0 - 2 | Asante KotokoAsante Kotoko |
| 07 Feb 21 | r13 | Eleven WondersEleven Wonder | 0 - 2 | Dreams FCDreams FC |
| 07 Feb 21 | r13 | Hearts of OakHearts of Oak | 1 - 1 | Legon CitiesLegon Cities |
| 08 Feb 21 | r13 | Elmina SharksElmina Sharks | 1 - 1 | Berekum ChelseaBerekum Chels |
| 09 Feb 21 | r13 | King FaisalKing Faisal | 1 - 0 | MedeamaMedeama |
| |
| 13 Feb 21 | r14 | WAFAWAFA | 0 - 0 | Ashanti GoldAshanti Gold |
| 14 Feb 21 | r14 | Berekum ChelseaBerekum Chels | 2 - 0 | Eleven WondersEleven Wonder |
| 14 Feb 21 | r14 | Dreams FCDreams FC | 4 - 2 | Aduana StarsAduana Stars |
| 14 Feb 21 | r14 | MedeamaMedeama | 2 - 0 | Bechem UnitedBechem United |
| 14 Feb 21 | r14 | Ebusua DwarfsEbusua Dwarfs | 1 - 2 | Karela UnitedKarela United |
| 14 Feb 21 | r14 | Liberty ProfessionalsLiberty Profe | 2 - 2 | Inter AlliesInter Allies |
| 15 Feb 21 | r14 | Legon CitiesLegon Cities | 1 - 1 | King FaisalKing Faisal |
| 16 Feb 21 | r14 | Great OlympicsGreat Olympic | 1 - 0 | Elmina SharksElmina Sharks |
| |
| 19 Feb 21 | r15 | Ashanti GoldAshanti Gold | 4 - 0 | Aduana StarsAduana Stars |
| 20 Feb 21 | r15 | Inter AlliesInter Allies | 1 - 0 | WAFAWAFA |
| 21 Feb 21 | r15 | Berekum ChelseaBerekum Chels | 1 - 0 | Dreams FCDreams FC |
| 21 Feb 21 | r15 | Hearts of OakHearts of Oak | 3 - 2 | Ebusua DwarfsEbusua Dwarfs |
| 21 Feb 21 | r15 | Elmina SharksElmina Sharks | 1 - 2 | MedeamaMedeama |
| 21 Feb 21 | r15 | Bechem UnitedBechem United | 1 - 1 | Legon CitiesLegon Cities |
| 21 Feb 21 | r15 | Karela UnitedKarela United | 2 - 0 | Liberty ProfessionalsLiberty Profe |
| 21 Feb 21 | r15 | Eleven WondersEleven Wonder | 1 - 0 | Great OlympicsGreat Olympic |
| |
| 24 Feb 21 | r16 | WAFAWAFA | 3 - 1 | Karela UnitedKarela United |
| 24 Feb 21 | r16 | MedeamaMedeama | 2 - 0 | Eleven WondersEleven Wonder |
| 24 Feb 21 | r16 | Ebusua DwarfsEbusua Dwarfs | 1 - 0 | King FaisalKing Faisal |
| 24 Feb 21 | r16 | Liberty ProfessionalsLiberty Profe | 0 - 1 | Hearts of OakHearts of Oak |
| 24 Feb 21 | r16 | Aduana StarsAduana Stars | 2 - 1 | Inter AlliesInter Allies |
| 24 Feb 21 | r16 | Legon CitiesLegon Cities | 2 - 0 | Elmina SharksElmina Sharks |
| 25 Feb 21 | r16 | Dreams FCDreams FC | 4 - 1 | Ashanti GoldAshanti Gold |
| 26 Feb 21 | r16 | Great OlympicsGreat Olympic | 1 - 0 | Berekum ChelseaBerekum Chels |
| |
| 28 Feb 21 | r14 | Asante KotokoAsante Kotoko | 0 - 0 | Hearts of OakHearts of Oak |
| |
| 05 Mar 21 | r17 | Inter AlliesInter Allies | 1 - 1 | Ashanti GoldAshanti Gold |
| 05 Mar 21 | r17 | Elmina SharksElmina Sharks | 1 - 0 | Asante KotokoAsante Kotoko |
| 06 Mar 21 | r17 | King FaisalKing Faisal | 1 - 0 | Liberty ProfessionalsLiberty Profe |
| 06 Mar 21 | r17 | Karela UnitedKarela United | 2 - 1 | Aduana StarsAduana Stars |
| 07 Mar 21 | r17 | Berekum ChelseaBerekum Chels | 1 - 1 | MedeamaMedeama |
| 07 Mar 21 | r17 | Dreams FCDreams FC | 0 - 1 | Great OlympicsGreat Olympic |
| 07 Mar 21 | r17 | Hearts of OakHearts of Oak | 4 - 0 | WAFAWAFA |
| 07 Mar 21 | r17 | Bechem UnitedBechem United | 1 - 1 | Ebusua DwarfsEbusua Dwarfs |
| 07 Mar 21 | r17 | Eleven WondersEleven Wonder | 1 - 0 | Legon CitiesLegon Cities |
| |
| 10 Mar 21 | r15 | King FaisalKing Faisal | 0 - 1 | Asante KotokoAsante Kotoko |
| |
| 02 Apr 21 | r18 | Great OlympicsGreat Olympic | 1 - 0 | MedeamaMedeama |
| 03 Apr 21 | r18 | Eleven WondersEleven Wonder | 1 - 1 | Asante KotokoAsante Kotoko |
| 04 Apr 21 | r18 | Dreams FCDreams FC | 1 - 1 | Inter AlliesInter Allies |
| 04 Apr 21 | r18 | King FaisalKing Faisal | 0 - 0 | WAFAWAFA |
| 04 Apr 21 | r18 | Elmina SharksElmina Sharks | 1 - 0 | Ebusua DwarfsEbusua Dwarfs |
| 04 Apr 21 | r18 | Bechem UnitedBechem United | 2 - 0 | Liberty ProfessionalsLiberty Profe |
| 04 Apr 21 | r18 | Karela UnitedKarela United | 1 - 1 | Ashanti GoldAshanti Gold |
| 04 Apr 21 | r18 | Berekum ChelseaBerekum Chels | 2 - 1 | Legon CitiesLegon Cities |
| 04 Apr 21 | r18 | Hearts of OakHearts of Oak | 2 - 0 | Aduana StarsAduana Stars |
| |
| 07 Apr 21 | r16 | Asante KotokoAsante Kotoko | 4 - 0 | Bechem UnitedBechem United |
| |
| 09 Apr 21 | r19 | Ebusua DwarfsEbusua Dwarfs | 1 - 1 | Eleven WondersEleven Wonder |
| 10 Apr 21 | r19 | Liberty ProfessionalsLiberty Profe | 4 - 0 | Elmina SharksElmina Sharks |
| 10 Apr 21 | r19 | Ashanti GoldAshanti Gold | 1 - 0 | Hearts of OakHearts of Oak |
| 11 Apr 21 | r19 | WAFAWAFA | 1 - 0 | Bechem UnitedBechem United |
| 11 Apr 21 | r19 | Legon CitiesLegon Cities | 2 - 0 | Great OlympicsGreat Olympic |
| 11 Apr 21 | r19 | MedeamaMedeama | 2 - 0 | Dreams FCDreams FC |
| 11 Apr 21 | r19 | Aduana StarsAduana Stars | 3 - 1 | King FaisalKing Faisal |
| 11 Apr 21 | r19 | Inter AlliesInter Allies | 2 - 0 | Karela UnitedKarela United |
| 11 Apr 21 | r19 | Asante KotokoAsante Kotoko | 2 - 0 | Berekum ChelseaBerekum Chels |
| |
| 16 Apr 21 | r20 | Great OlympicsGreat Olympic | 0 - 0 | Asante KotokoAsante Kotoko |
| 17 Apr 21 | r20 | King FaisalKing Faisal | 0 - 0 | Ashanti GoldAshanti Gold |
| 17 Apr 21 | r20 | Elmina SharksElmina Sharks | 1 - 0 | WAFAWAFA |
| 18 Apr 21 | r20 | Berekum ChelseaBerekum Chels | 2 - 1 | Ebusua DwarfsEbusua Dwarfs |
| 18 Apr 21 | r20 | MedeamaMedeama | 2 - 1 | Legon CitiesLegon Cities |
| 18 Apr 21 | r20 | Bechem UnitedBechem United | 4 - 0 | Aduana StarsAduana Stars |
| 18 Apr 21 | r20 | Eleven WondersEleven Wonder | 0 - 1 | Liberty ProfessionalsLiberty Profe |
| 18 Apr 21 | r20 | Hearts of OakHearts of Oak | 1 - 0 | Inter AlliesInter Allies |
| 19 Apr 21 | r20 | Dreams FCDreams FC | 1 - 0 | Karela UnitedKarela United |
| |
| 24 Apr 21 | r21 | Liberty ProfessionalsLiberty Profe | 2 - 0 | Berekum ChelseaBerekum Chels |
| 24 Apr 21 | r21 | Asante KotokoAsante Kotoko | 1 - 2 | MedeamaMedeama |
| 24 Apr 21 | r21 | Ebusua DwarfsEbusua Dwarfs | 4 - 1 | Great OlympicsGreat Olympic |
| 25 Apr 21 | r21 | Inter AlliesInter Allies | 0 - 1 | King FaisalKing Faisal |
| 25 Apr 21 | r21 | Ashanti GoldAshanti Gold | 4 - 0 | Bechem UnitedBechem United |
| 25 Apr 21 | r21 | Legon CitiesLegon Cities | 1 - 1 | Dreams FCDreams FC |
| 25 Apr 21 | r21 | Aduana StarsAduana Stars | 2 - 1 | Elmina SharksElmina Sharks |
| 25 Apr 21 | r21 | WAFAWAFA | 1 - 0 | Eleven WondersEleven Wonder |
| 25 Apr 21 | r21 | Karela UnitedKarela United | 1 - 1 | Hearts of OakHearts of Oak |
| |
| 30 Apr 21 | r22 | Berekum ChelseaBerekum Chels | 2 - 3 | WAFAWAFA |
| 01 May 21 | r22 | Eleven WondersEleven Wonder | 2 - 1 | Aduana StarsAduana Stars |
| 01 May 21 | r22 | Legon CitiesLegon Cities | 0 - 1 | Asante KotokoAsante Kotoko |
| 02 May 21 | r22 | Great OlympicsGreat Olympic | 2 - 0 | Liberty ProfessionalsLiberty Profe |
| 02 May 21 | r22 | Dreams FCDreams FC | 2 - 0 | Hearts of OakHearts of Oak |
| 02 May 21 | r22 | King FaisalKing Faisal | 1 - 1 | Karela UnitedKarela United |
| 02 May 21 | r22 | MedeamaMedeama | 3 - 0 | Ebusua DwarfsEbusua Dwarfs |
| 02 May 21 | r22 | Elmina SharksElmina Sharks | 2 - 1 | Ashanti GoldAshanti Gold |
| 02 May 21 | r22 | Bechem UnitedBechem United | 2 - 1 | Inter AlliesInter Allies |
| |
| 07 May 21 | r23 | WAFAWAFA | 2 - 3 | Great OlympicsGreat Olympic |
| 08 May 21 | r23 | Asante KotokoAsante Kotoko | 3 - 1 | Dreams FCDreams FC |
| 09 May 21 | r23 | Inter AlliesInter Allies | 2 - 0 | Elmina SharksElmina Sharks |
| 09 May 21 | r23 | Ashanti GoldAshanti Gold | 1 - 1 | Eleven WondersEleven Wonder |
| 09 May 21 | r23 | Ebusua DwarfsEbusua Dwarfs | 0 - 3 | Legon CitiesLegon Cities |
| 09 May 21 | r23 | Liberty ProfessionalsLiberty Profe | 0 - 0 | MedeamaMedeama |
| 09 May 21 | r23 | Aduana StarsAduana Stars | 1 - 0 | Berekum ChelseaBerekum Chels |
| 09 May 21 | r23 | Karela UnitedKarela United | 2 - 1 | Bechem UnitedBechem United |
| 09 May 21 | r23 | Hearts of OakHearts of Oak | 2 - 0 | King FaisalKing Faisal |
| |
| 12 May 21 | r24 | Berekum ChelseaBerekum Chels | 3 - 1 | Ashanti GoldAshanti Gold |
| 12 May 21 | r24 | Dreams FCDreams FC | 3 - 0 | King FaisalKing Faisal |
| 12 May 21 | r24 | MedeamaMedeama | 1 - 2 | WAFAWAFA |
| 12 May 21 | r24 | Elmina SharksElmina Sharks | 1 - 1 | Karela UnitedKarela United |
| 12 May 21 | r24 | Bechem UnitedBechem United | 0 - 1 | Hearts of OakHearts of Oak |
| 12 May 21 | r24 | Eleven WondersEleven Wonder | 1 - 1 | Inter AlliesInter Allies |
| 12 May 21 | r24 | Legon CitiesLegon Cities | 2 - 1 | Liberty ProfessionalsLiberty Profe |
| 13 May 21 | r24 | Asante KotokoAsante Kotoko | 2 - 1 | Ebusua DwarfsEbusua Dwarfs |
| 13 May 21 | r24 | Great OlympicsGreat Olympic | 2 - 3 | Aduana StarsAduana Stars |
| |
| 15 May 21 | r25 | WAFAWAFA | 1 - 0 | Legon CitiesLegon Cities |
| 16 May 21 | r25 | Inter AlliesInter Allies | 5 - 0 | Berekum ChelseaBerekum Chels |
| 16 May 21 | r25 | King FaisalKing Faisal | 3 - 1 | Bechem UnitedBechem United |
| 16 May 21 | r25 | Ashanti GoldAshanti Gold | 1 - 0 | Great OlympicsGreat Olympic |
| 16 May 21 | r25 | Liberty ProfessionalsLiberty Profe | 1 - 1 | Asante KotokoAsante Kotoko |
| 16 May 21 | r25 | Aduana StarsAduana Stars | 2 - 0 | MedeamaMedeama |
| 16 May 21 | r25 | Karela UnitedKarela United | 2 - 0 | Eleven WondersEleven Wonder |
| 16 May 21 | r25 | Hearts of OakHearts of Oak | 2 - 0 | Elmina SharksElmina Sharks |
| 17 May 21 | r25 | Ebusua DwarfsEbusua Dwarfs | 1 - 1 | Dreams FCDreams FC |
| |
| 21 May 21 | r26 | Eleven WondersEleven Wonder | 0 - 1 | Hearts of OakHearts of Oak |
| 22 May 21 | r26 | Asante KotokoAsante Kotoko | 1 - 1 | WAFAWAFA |
| 22 May 21 | r26 | Great OlympicsGreat Olympic | 1 - 0 | Inter AlliesInter Allies |
| 23 May 21 | r26 | Berekum ChelseaBerekum Chels | 1 - 1 | Karela UnitedKarela United |
| 23 May 21 | r26 | Dreams FCDreams FC | 2 - 1 | Bechem UnitedBechem United |
| 23 May 21 | r26 | Legon CitiesLegon Cities | 2 - 0 | Aduana StarsAduana Stars |
| 23 May 21 | r26 | MedeamaMedeama | 1 - 0 | Ashanti GoldAshanti Gold |
| 23 May 21 | r26 | Ebusua DwarfsEbusua Dwarfs | 2 - 1 | Liberty ProfessionalsLiberty Profe |
| 23 May 21 | r26 | Elmina SharksElmina Sharks | 0 - 1 | King FaisalKing Faisal |
| |
| 28 May 21 | r27 | Karela UnitedKarela United | 1 - 1 | Great OlympicsGreat Olympic |
| 29 May 21 | r27 | Liberty ProfessionalsLiberty Profe | 2 - 1 | Dreams FCDreams FC |
| 29 May 21 | r27 | Aduana StarsAduana Stars | 0 - 0 | Asante KotokoAsante Kotoko |
| 30 May 21 | r27 | Inter AlliesInter Allies | 3 - 0 | MedeamaMedeama |
| 30 May 21 | r27 | WAFAWAFA | 2 - 1 | Ebusua DwarfsEbusua Dwarfs |
| 30 May 21 | r27 | King FaisalKing Faisal | 0 - 1 | Eleven WondersEleven Wonder |
| 30 May 21 | r27 | Ashanti GoldAshanti Gold | 0 - 1 | Legon CitiesLegon Cities |
| 30 May 21 | r27 | Bechem UnitedBechem United | 1 - 1 | Elmina SharksElmina Sharks |
| 30 May 21 | r27 | Hearts of OakHearts of Oak | 2 - 0 | Berekum ChelseaBerekum Chels |
| |
| 05 Jun 21 | r28 | MedeamaMedeama | 1 - 0 | Karela UnitedKarela United |
| 06 Jun 21 | r28 | Asante KotokoAsante Kotoko | 1 - 0 | Ashanti GoldAshanti Gold |
| 06 Jun 21 | r28 | Berekum ChelseaBerekum Chels | 5 - 0 | King FaisalKing Faisal |
| 06 Jun 21 | r28 | Dreams FCDreams FC | 2 - 0 | Elmina SharksElmina Sharks |
| 06 Jun 21 | r28 | Ebusua DwarfsEbusua Dwarfs | 1 - 0 | Aduana StarsAduana Stars |
| 06 Jun 21 | r28 | Liberty ProfessionalsLiberty Profe | 3 - 2 | WAFAWAFA |
| 06 Jun 21 | r28 | Eleven WondersEleven Wonder | 2 - 1 | Bechem UnitedBechem United |
| 06 Jun 21 | r28 | Great OlympicsGreat Olympic | 1 - 1 | Hearts of OakHearts of Oak |
| 07 Jun 21 | r28 | Legon CitiesLegon Cities | 1 - 0 | Inter AlliesInter Allies |
| |
| 11 Jun 21 | r29 | Elmina SharksElmina Sharks | 2 - 1 | Eleven WondersEleven Wonder |
| 13 Jun 21 | r29 | WAFAWAFA | 1 - 1 | Dreams FCDreams FC |
| 13 Jun 21 | r29 | King FaisalKing Faisal | 1 - 0 | Great OlympicsGreat Olympic |
| 13 Jun 21 | r29 | Ashanti GoldAshanti Gold | 1 - 0 | Ebusua DwarfsEbusua Dwarfs |
| 13 Jun 21 | r29 | Aduana StarsAduana Stars | 2 - 0 | Liberty ProfessionalsLiberty Profe |
| 13 Jun 21 | r29 | Bechem UnitedBechem United | 2 - 0 | Berekum ChelseaBerekum Chels |
| 13 Jun 21 | r29 | Karela UnitedKarela United | 2 - 0 | Legon CitiesLegon Cities |
| 13 Jun 21 | r29 | Hearts of OakHearts of Oak | 2 - 0 | MedeamaMedeama |
| 14 Jun 21 | r29 | Inter AlliesInter Allies | 2 - 3 | Asante KotokoAsante Kotoko |
| |
| 23 Jun 21 | r30 | Asante KotokoAsante Kotoko | 2 - 1 | Karela UnitedKarela United |
| 23 Jun 21 | r30 | Berekum ChelseaBerekum Chels | 2 - 1 | Elmina SharksElmina Sharks |
| 23 Jun 21 | r30 | Great OlympicsGreat Olympic | 1 - 0 | Bechem UnitedBechem United |
| 23 Jun 21 | r30 | Dreams FCDreams FC | 2 - 1 | Eleven WondersEleven Wonder |
| 23 Jun 21 | r30 | WAFAWAFA | 3 - 2 | Aduana StarsAduana Stars |
| 24 Jun 21 | r30 | MedeamaMedeama | 1 - 1 | King FaisalKing Faisal |
| 24 Jun 21 | r30 | Ebusua DwarfsEbusua Dwarfs | 1 - 0 | Inter AlliesInter Allies |
| 24 Jun 21 | r30 | Liberty ProfessionalsLiberty Profe | 1 - 5 | Ashanti GoldAshanti Gold |
| 24 Jun 21 | r30 | Legon CitiesLegon Cities | 1 - 2 | Hearts of OakHearts of Oak |
| |
| 26 Jun 21 | r31 | Eleven WondersEleven Wonder | 3 - 1 | Berekum ChelseaBerekum Chels |
| 27 Jun 21 | r31 | Inter AlliesInter Allies | 0 - 2 | Liberty ProfessionalsLiberty Profe |
| 27 Jun 21 | r31 | Ashanti GoldAshanti Gold | 0 - 0 | WAFAWAFA |
| 27 Jun 21 | r31 | Hearts of OakHearts of Oak | 1 - 0 | Asante KotokoAsante Kotoko |
| 27 Jun 21 | r31 | Elmina SharksElmina Sharks | 1 - 1 | Great OlympicsGreat Olympic |
| 27 Jun 21 | r31 | Aduana StarsAduana Stars | 2 - 0 | Dreams FCDreams FC |
| 27 Jun 21 | r31 | Bechem UnitedBechem United | 0 - 0 | MedeamaMedeama |
| 28 Jun 21 | r31 | King FaisalKing Faisal | 2 - 0 | Legon CitiesLegon Cities |
| 28 Jun 21 | r31 | Karela UnitedKarela United | 1 - 4 | Ebusua DwarfsEbusua Dwarfs |
| |
| 03 Jul 21 | r32 | Asante KotokoAsante Kotoko | 1 - 1 | King FaisalKing Faisal |
| 03 Jul 21 | r32 | WAFAWAFA | 1 - 0 | Inter AlliesInter Allies |
| 03 Jul 21 | r32 | Legon CitiesLegon Cities | 1 - 1 | Bechem UnitedBechem United |
| 04 Jul 21 | r32 | Great OlympicsGreat Olympic | 0 - 1 | Eleven WondersEleven Wonder |
| 04 Jul 21 | r32 | Dreams FCDreams FC | 0 - 1 | Berekum ChelseaBerekum Chels |
| 04 Jul 21 | r32 | MedeamaMedeama | 3 - 2 | Elmina SharksElmina Sharks |
| 04 Jul 21 | r32 | Liberty ProfessionalsLiberty Profe | 3 - 2 | Karela UnitedKarela United |
| 04 Jul 21 | r32 | Ebusua DwarfsEbusua Dwarfs | 1 - 1 | Hearts of OakHearts of Oak |
| 05 Jul 21 | r32 | Aduana StarsAduana Stars | 1 - 0 | Ashanti GoldAshanti Gold |
| |
| 11 Jul 21 | r33 | King FaisalKing Faisal | 2 - 0 | Ebusua DwarfsEbusua Dwarfs |
| 11 Jul 21 | r33 | Inter AlliesInter Allies | 2 - 4 | Aduana StarsAduana Stars |
| 11 Jul 21 | r33 | Berekum ChelseaBerekum Chels | 2 - 1 | Great OlympicsGreat Olympic |
| 11 Jul 21 | r33 | Ashanti GoldAshanti Gold | 0 - 0 | Dreams FCDreams FC |
| 11 Jul 21 | r33 | Hearts of OakHearts of Oak | 1 - 1 | Liberty ProfessionalsLiberty Profe |
| 11 Jul 21 | r33 | Elmina SharksElmina Sharks | 2 - 0 | Legon CitiesLegon Cities |
| 11 Jul 21 | r33 | Bechem UnitedBechem United | 2 - 1 | Asante KotokoAsante Kotoko |
| 11 Jul 21 | r33 | Karela UnitedKarela United | 0 - 2 | WAFAWAFA |
| 11 Jul 21 | r33 | Eleven WondersEleven Wonder | 3 - 1 | MedeamaMedeama |
| |
| 17 Jul 21 | r34 | Great OlympicsGreat Olympic | 2 - 1 | Dreams FCDreams FC |
| 17 Jul 21 | r34 | WAFAWAFA | 1 - 0 | Hearts of OakHearts of Oak |
| 17 Jul 21 | r34 | Ashanti GoldAshanti Gold | 7 - 0 | Inter AlliesInter Allies |
| 18 Jul 21 | r34 | Asante KotokoAsante Kotoko | 0 - 1 | Elmina SharksElmina Sharks |
| 18 Jul 21 | r34 | Legon CitiesLegon Cities | 3 - 2 | Eleven WondersEleven Wonder |
| 18 Jul 21 | r34 | MedeamaMedeama | 1 - 0 | Berekum ChelseaBerekum Chels |
| 18 Jul 21 | r34 | Ebusua DwarfsEbusua Dwarfs | 2 - 1 | Bechem UnitedBechem United |
| 18 Jul 21 | r34 | Liberty ProfessionalsLiberty Profe | 0 - 0 | King FaisalKing Faisal |
| 18 Jul 21 | r34 | Aduana StarsAduana Stars | 2 - 1 | Karela UnitedKarela United |
Team 2020-2021 Schedules
Aduana Stars
Asante Kotoko
Basake Holy Stars
Bechem United
Berekum Chelsea
Bibiani Gold Stars
Dreams FC
Eleven Wonders
Heart of Lions
Hearts of Oak
Hohoe United
Karela United
Medeama
Nations FC
Samartex
Swedru All Blacks
Vision
Young Apostles
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